Cdis016278.1
Basic Information
- Insect
- Ceraclea dissimilis
- Gene Symbol
- MBD3
- Assembly
- GCA_963576895.1
- Location
- OY756374.1:15251141-15258637[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 6.2e-26 2.4e-22 78.7 0.0 2 73 6 72 5 76 0.93 2 2 0.00023 0.93 9.5 0.0 28 72 85 146 73 150 0.76
Sequence Information
- Coding Sequence
- ATGAGTGTGTCCATTGAGAAGAAGAAATCCGAATGTGCGGCACTTCCAAAAGGTTGGCAGAGAGAAGAGATTTTGAGAAAATCTGGATTGTCTGCCGGAAAAGTGGATGTTTATTACTATAGCCCGTCCGGTAAGAAGTTCCACAGTAAACCGCAGTTGGCTCGTTATTTGGGCGACTCCCTGGACCTAGCGTGCTTTGACTTCCAGCGAGGGAGAATAAACACAATGTTACTGCGGAAAAACAAGAAACCACGAGGCACGCAGTTTGATTACAGTCGAGGAGTGAGATCAGACGCATCGCTGGTCCCACCAATCCGACAGACGGCTTCCATCTTCAAGCAGCCCGTCACGGTCGTTAAAACACAGGAGAGTAAAGTTAAGACTGACTTCAAGCACGGACCTCAGGACAAACCCAAGCAGCTGTTCTGGGAGAAGAGACTGGAGGGTTTGAGTGCGTGTGATTCCTGGGGGGTGTTGGGAGGAGCCACTCTTCCAAAGAATATCAAATCCTTTGGCCCCTTTGTCAGTGATGCCACGACTATTCAAGCCCTAGCCACGGCCCTTCACGTGCAGCCACAGCCCGTCACAGGACAATGCGGTCTAAAGTCGGCCATAACTCAGAATCCCGGAGTGTTTTTAAATCCGGAACAACCCCTCGTACAATCCGTGACTGTCGTGGAAGAGGACATTAGACGGCAAGAGGAAAGAGTGAACAGGGCTCGAAGAAAATTACAGAACGCTCTGTTGGCCTGTAATCCTCCCCCACCTACGTAA
- Protein Sequence
- MSVSIEKKKSECAALPKGWQREEILRKSGLSAGKVDVYYYSPSGKKFHSKPQLARYLGDSLDLACFDFQRGRINTMLLRKNKKPRGTQFDYSRGVRSDASLVPPIRQTASIFKQPVTVVKTQESKVKTDFKHGPQDKPKQLFWEKRLEGLSACDSWGVLGGATLPKNIKSFGPFVSDATTIQALATALHVQPQPVTGQCGLKSAITQNPGVFLNPEQPLVQSVTVVEEDIRRQEERVNRARRKLQNALLACNPPPPT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00023790;
- 90% Identity
- iTF_00179359;
- 80% Identity
- -