Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.011 1.5e+02 3.7 0.1 16 43 121 149 114 154 0.68

2 5 0.0049 63 4.9 0.0 22 45 157 180 153 187 0.85

3 5 0.001 13 7.0 0.1 22 45 185 208 179 211 0.88

4 5 3.6e-05 0.47 11.7 0.1 21 52 212 243 210 243 0.88

5 5 0.00095 12 7.1 0.0 21 48 240 267 236 269 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.011	1.5e+02	3.7	0.1	16	43	121	149	114	154	0.68
2	5	0.0049	63	4.9	0.0	22	45	157	180	153	187	0.85
3	5	0.001	13	7.0	0.1	22	45	185	208	179	211	0.88
4	5	3.6e-05	0.47	11.7	0.1	21	52	212	243	210	243	0.88
5	5	0.00095	12	7.1	0.0	21	48	240	267	236	269	0.90

Coding Sequence: ATGTGGCAATGTTATAGCCAACCATCTAAACTTGTTTTTGGTACTAATGTCATCCCCTCTCAAGTTGGAGCTCAACAAGCAGATCCGGCTGGACCATTAGCATTTTGTGGGGAAGACTCCTACTACGATGACGATGTCATCGATACAAGTCACATACAAGCACAAATTGGTCCCGAGGTATCTCTTATACCAGTCAAAAAGAATCCAATCAAAATTAAAATGTTTGGAAAGCTTTCGTGTAAGGATAAATCCAATTTGGAAGTGTACAAAATTCAAAAAATAGTGCAACAAAGATCTCCACGTCAAAACGTAAGACTGATATCGAAAGAAGAAGAGATACAAGCAGAAACAGAGGTTATAAATTCAAAACGAAAATCACTTCCACTGGAGAAGTGTCCTATTTGTAAGAAATTTTTCCGCCGCATGAAAACTCATCTACAAAAGCACGAAAATGTTACTCGAGATCCAAACGATCCATTAACATGCCAATTTTGTAAGAAAGTTTTTAATACCGGCAGTAATTTAAGTATACACATGCGTACCCACACGGGTGACAAACCATACATATGCGAGATATGTACGAAAGGTTTTGCACAATCATGTAATTTGATTAATCATATGCGTATTCACACAGGTGAGAGGCCTTTTAAATGTCCGCATTGTGACCGTGCTTTTACACAATCAGGCAACCTAAATAATCACGTAAGATTACATACTGACGAAAAACCATTTAAATGTCACTTTTGTGAAAAAGCATTTACTCAATCAGGCAACCTCAATTCCCATATTCGAAACAATCACAAAATTCCAAACATAGAAAACGATTTGAGTGATATCGAACTGGTTCAGTAA
Protein Sequence: MWQCYSQPSKLVFGTNVIPSQVGAQQADPAGPLAFCGEDSYYDDDVIDTSHIQAQIGPEVSLIPVKKNPIKIKMFGKLSCKDKSNLEVYKIQKIVQQRSPRQNVRLISKEEEIQAETEVINSKRKSLPLEKCPICKKFFRRMKTHLQKHENVTRDPNDPLTCQFCKKVFNTGSNLSIHMRTHTGDKPYICEICTKGFAQSCNLINHMRIHTGERPFKCPHCDRAFTQSGNLNNHVRLHTDEKPFKCHFCEKAFTQSGNLNSHIRNNHKIPNIENDLSDIELVQ

Sequence clustering based on sequence similarity using MMseqs2