Bmaj008392.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombylius major
Gene Symbol
Lztr1
Assembly
GCA_932526615.1
Location
CAKOBF010000140.1:291798-294808[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1.1e-13 1.4e-11 44.7 0.1 1 107 366 497 366 500 0.84
2 4 0.74 97 3.4 0.1 77 108 499 530 497 532 0.90
3 4 1.4e-19 1.9e-17 63.6 0.0 8 97 591 680 585 695 0.85
4 4 2.2 2.9e+02 1.8 0.1 72 106 689 723 681 726 0.86

Sequence Information

Coding Sequence
ATGTCACATTCCACATCAAATTCTATAAAAGGTCACCACAAGTCTATATCACCGGGAAGTTTCAGTTGTAATGCACTAAATGTGGACTTTTCATCATATACGGCTACACATCAATGGACAAAGACATTAGATTGTGCAGAATTTGTTGGAGCAAAACGGAGTAAACATACCGTTGTTGCTTACAAGGATGCAATGTATGTTTTTGGTGGTGATAATGGAAAAACAATGCTTAATGATCTAATACGATTTGGTGTTAAAGACAAGTCATGGGGCAGAGCATGTGCAACTGGTACACCTCCTGCACCAAGATACCATCATTCAGCAGTCGTTTATGGAAGTTCAATGTTTATATTTGGCGGTTATACAGGTGATATTCATTCAAATTCAAATTTAACAAACAAAAATGATCTCTTCGAGTATAAATTTCAAAACGCACAATGGGTTGAATGGAAATTTAGCGGAAAAACAACTCCAGTTCCAAGATCAGCTCATGGAGCAGCTGTTTATGATAACAAACTTTGGATTTATGCAGGTTATGATGGAAATGCAAGACTTAATGACATGTGGACTCTGGATTTGACGAGTGAAGTACATCAATGGGAAGAAATTGAACAGAAAGGTGATCGTCCACCGACCTGTTGTAATTTTCCAGTTGCTGTTGCTCGAGATTGTATGTATGTGTTCTCCGGACAAAGTGGATTACAAATAACTAATGCATTATTTGAATTTCATTTTAAAAAGAAAACTTGGACAAAAATTTCAAATGAACATGTTTTACGTGGTGCATCAGCACCACCATCACGTCGTTATGGTCATACTATGGTACATCATGATCGTTTCTTATACGTTTTTGGTGGCTCTGCAGATTCAACATTACCAAATGATTTACATTGTTATGATTTAGATTCACAAGTTTGGTCAATAATAACACCAGAAGCAAATTCACAAGTACCATCTGGTCGTGTATTTCATGCTTCAGCAGTTATTGGAGATGCAATGTATATTTTTGGTGGTACTGTAGATAATAGTGTTAGACGAGGTGATACATACCGTTTTCAATTTTCAAGTTATCCACGTTGTACATTACGTGATGATTTTGGTAAATTTTTCAATGAGAAACAATTTTGTGATATTCAATTTATTGTTGGACCAGAAGAAATTAAAATTCAAGCTCATATTGCAATGGTTGCAGCCCGATCAAAATTTTTAAGAACAAAAATATTAGCTGCTCGTGATGCAAGTAATCAACATCTTGAAAAATTATTTGGAACTCTTGATGTACCATTCACTGATAGACCCATGTTAGAAGTTCGTTTACCAAATGCTACACCAGAAGCTTTTGAAATTATTCTAAATTACGTTTATACAGATCGAATTGATTTGAAGGAATCATACAGTAAAAATATTGTTATACTTATAACGGATATATACCAATTGGCTGGACAATTTTTGATGCCACGTCTTGCACAAGGATGTATTCAATATTTAGACTTTAAAATCTCCAAAACAAATGTTTTAGAAGCTCTCTACAATGCAGATAAAAATAAAATTCAAATTGTCAAAGATCATTGTATGGCATTCATTGTAAAAGATGAAAATTTCTCTGAAGTCGTTATGTCCAGTGAATTCAGTGATCTTGATAAATCATTACTTGTTGAAATTATTCGTAAAAGGCTTAATCCAGGAAAAATAACAGTCGAAGTAAATTATGATAAAAATACTGGAACAACACTTGAAAGTGATATGGCAGCATTCTTAGAATCCAGCGGAAAGGATTTTTGCGATATTCATCTTGTGTTGGATGGTCATGTAATTCCAGCACATAAATCAATTTTATCAGCACGTTGCTCTTATTTTCAAGCAATGTTTAGATCTTTTATGCCACCAGATAATACAGTTAATATTCAAATTGGTGAAATTTCTCCATCATTGGAAGCATTTAATTCACTTTTACGTTATATTTATTATGGTGAAACAAAATTACCACCACAAGATTCATTATATTTATTTCAAGCCCCCTGTTTTTATGGGCTCTCAAACAATCGTTTGCATTCGTTTTGTAAATATTCTTTGGAACATAATATCACATATGAGAATGTGTTGCAGACATTGGAAGCAGCAGACATAACAAAAGTTTATGACATTAAAGAACATGCATTAAAATTGATTGTTAAAGAATTTTCAACGGTTGCAAGATTACCAAAAATGAGTACATTAAGTCGTGAACTTCTATTAGAGATTATACGTGCTGTAGCTGATGCACATGGAGAATTTCTAATGACTCAAGACCTATCATCTATCAGTATTAATACAGATCTCTGA
Protein Sequence
MSHSTSNSIKGHHKSISPGSFSCNALNVDFSSYTATHQWTKTLDCAEFVGAKRSKHTVVAYKDAMYVFGGDNGKTMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVYGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQNAQWVEWKFSGKTTPVPRSAHGAAVYDNKLWIYAGYDGNARLNDMWTLDLTSEVHQWEEIEQKGDRPPTCCNFPVAVARDCMYVFSGQSGLQITNALFEFHFKKKTWTKISNEHVLRGASAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSIITPEANSQVPSGRVFHASAVIGDAMYIFGGTVDNSVRRGDTYRFQFSSYPRCTLRDDFGKFFNEKQFCDIQFIVGPEEIKIQAHIAMVAARSKFLRTKILAARDASNQHLEKLFGTLDVPFTDRPMLEVRLPNATPEAFEIILNYVYTDRIDLKESYSKNIVILITDIYQLAGQFLMPRLAQGCIQYLDFKISKTNVLEALYNADKNKIQIVKDHCMAFIVKDENFSEVVMSSEFSDLDKSLLVEIIRKRLNPGKITVEVNYDKNTGTTLESDMAAFLESSGKDFCDIHLVLDGHVIPAHKSILSARCSYFQAMFRSFMPPDNTVNIQIGEISPSLEAFNSLLRYIYYGETKLPPQDSLYLFQAPCFYGLSNNRLHSFCKYSLEHNITYENVLQTLEAADITKVYDIKEHALKLIVKEFSTVARLPKMSTLSRELLLEIIRAVADAHGEFLMTQDLSSISINTDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01055302;
90% Identity
iTF_01461249; iTF_00118785; iTF_00424738; iTF_00455011; iTF_01431012; iTF_00937382; iTF_01432136; iTF_00936654; iTF_01540432; iTF_01519411; iTF_00877173; iTF_00453656; iTF_00717880; iTF_01256474; iTF_01049756; iTF_00628447; iTF_01183904;
80% Identity
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