Basic Information

Insect: Bombus sibiricus
Gene Symbol: -
Assembly: GCA_014737505.1
Location: JACXIM010000050.1:2616262-2623502[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.6e-16 2.7e-12 46.5 0.1 10 71 228 287 222 291 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.6e-16	2.7e-12	46.5	0.1	10	71	228	287	222	291	0.90

Sequence Information

Coding Sequence: ATGGACGGTATTAATGTGAATGGCGGGAATGCCGATGGGGCGCGCGAGGATCCTAACCTAGAAGCTGGTAGTATGCCGAATCTACAAGAGACGCAAGTTAAAGTGGATACCTCTAAAATGGATGGGCAGGACGTGAACGGCGACATTAGGAACTCGCCGAAAAAGGGACGCAAACGGAAGCTATCGGAACCGGACGATCTTAGCTCAGAGGAGTCTATGGAATTCAATGGTTTTGATATACAAGGAGATAACGAAGTGGAGCCAGCAAGTCATGTCTTGAAGAAATTAATTGCTGAAGCTGAAGTAGCAGAGGCACAATTGGCAAAACGATTTAGATATAGTATAAGGAAGAATTTTGATACAAAAAAAGATGATGAAGATTCGGATGATAACAGAATGCACGATAGTGAACATGTATTAGATATAGATAAAGTAAAGAAGGAAAAGGAATCTGATAAATCAGAAACAGAATCACTTGGAATGCCAAATACTGTTGAATCAGAAACAGAAGTACAAAAAACAGATGACACTTCCCTTAAGTCAACAAATTCATCATCTGCAGCCAGTAGTCCAGCAACATCGATAAAGTCTAAAGGTTATCGTTTATTACGTGGAGTTAGTCCAGGAAGTACTGGAAAACAAAAAGTATCAAGTGATATATCAAATCCAGCATTCAAAGAGCCTTTTAAGTATGGTTGGAGACGAGAATTGGTATTCAGAGCAAGTAATGATTCTAGTCTTAAAAGAATGGCTGATATCTATTATTATACACCAAAGGGCAAAAAGGTTAGAAGTTTCAGAGAAGTTGCAGAATTTCTTAATACGAAAGAGTTAACTATTGATAATTTTACTTTCCTCAAAGAACCAATTGGTCCTGATGATCCGGAAAAAGAGATTATTCGAGACGCAAAAAGAATGAGGGGACCTGGAATATCAGCTACTCCACCAAGAAAGAGTATAGGGTATAAGAGAGGTACACCTGGTAAAAGGGTTATAGAAGAACCTGCATCAGTGCCCGTTCCAGTGGCTACAAAAGCTACTACGAAATCACCAAAAGCTGCATCAACAGGATTTAAGGTGAAAGTGTCTGCAAAGAAAACCCCACACATAACAGAAATAAAGTCACCTTCTCAAGAAAGGGAGATACTTCCACCTCAAAGAACAACAAGTACAAGAAGAAGTCAGCTACCTGTAGAAAAACCACCGCCTCCTAAACCAAAAAGACAATTAACGCCCAAAGTTCAAGAACCATGCAGTATAAGATGCTCAACCAGTATGGGGTTGATACCAAGCTTACAATGTCGTGTGTGTCTCTGTTTATATCATCCTGAGTGTGTTGGTGGTACAGAGTTTGCAGGAAGTGACAATTATGTTTGCAAGAACTGTCAACAAGATACTAATGAATCTCATCAATCTCAAACGAATCCATCTTTGACACCTCCTCCACTGATACCAATCAGTATGCTAGGTGCACAAAATACAAAGTCAAAACATCAAGTAAATCTAAGTCCTCCAAAGCTTCAACGAATACCCAAATCTGATAATGCAGATTCACAATCGCGAAATGCTACTAAAATTTTAAAAACATCCTCTGCAACATCACATTCTCCTTTAAATTCAGATAATAAAGAAAGCAGTTGGTTTGCTCAAACAGAAAACGAATTTTTACAAAGTCATGACGGAATTTTACCAAAACCGGCCCAGAATATTGCTCTAATGGGGGGCAAGAGATATATTGTTGTACCAAAAAATAATGCTATGGCTGTTCAGCCAGCTATAACTGTGAAGCCTGATAAAATTGGTGATAAACCTCCTATACTTCAGGATGGTACACTTACGGATATATCAAACGCTGTTGACAATTCTATGTCCACAAAAGCACGTACTTCTTTAACAACAAAATTTGTGGAAAAAGATGCTTTTGATAAATCAATTGATAAAGACATGTCAAAAGATGCATCGCATACAGGACTTCCACCAAGTTCCATAATAGAGAAAGCCAATGAAACGTGCAATAGTAATGATAGAACTGATATATTGACTGCAACTAAATCACAAAATGACTTATCTAGTACAACAGATCTTGCAATAGAAAGTAAGAAATCAGAAAATTGTAACACAGTTGAAAAGAAGAGTATAGTAAAGAATTCAAATACAACTAACACAAATAATGACTTATTTAAAGTAGATACACAACATTTTGTGACAAGTAGTTTGGGTACTGTTAAAATAAGCAGCAAAAGGAAACAAAATCGGCAGGATAAAGAACAACAGCAGCATTTTATGGATTCAGTGTGTGCCGGTTATCATGCATTGCTGCGCATATTTCAATACCTTAAGGTACAAGAATTACTTCGGGCTGCAAGAGTGTGTAAAATGTGGCGAGATTTGGCTGCGCATCCTTCTCTGTGGAAAACTGTACGAATGAAAAATAGTCAAGTAACAGATTGGGATGGCTTAGCAGATACATTACAGAGGCATGGTACTCAACATTTAGATCTTCGAAAAATGCTTGTAGCAGGCGAATCTGACAGCATTTGGGAGAAGTTTTTAGTAGTAATACCACGTGTAACTAGCCTTGTCAAACTAGAATTATGTAAATGTCCTGTGATGGTTGTTGAAGAAGTTATTAGAAGTTGCCCTCAGTTAGAAGTATTGAGTGCAATGTCGATAAAGTGTGACTCCCTAAATTTAGAGTCAGTTGGAAATCTTAAACGTTGTCAAGAATTAAGGCTTAAAGCAATCAGTGGTATGTCTTTAAAAGAAGATCTCACACCTCTACAAGAACTAACGCAACTAACACAGTTGAGTTTGACATCAGTTAAGGAACTTGGAAAGAAGGGAATTAATATAATACAAGCATTAGTTAATTTGGAAACTCTAGAATTGGGTGAATGCTCAGATTTTCCAGATAAATTTGGTACTACAGTTTTAATAAAGTTACAAAAATTAGAACGTCTTAGGTTGGAAAAGGGTCAAGGCTCATGTTGTACATTTGACATTTTGGAAGGTGTATCTAAGTTACAAAACTTAAGTCAAATGGAACTGGTCAATTTTGATGTCAAAAATGGCTTTGACAAATGTCTTGCAAACTGCAAGAATATTAAAAGGCTGTTAATTATACCAACGTACATATCTCAATCGGCAACGTCTAACAATATGGTGCTTGGAGGTGTTACTGAACTATCGAATAATTTGACGCATTTCGTATGGGGCGTTACACTTGAGTTACTTAGGGTTACAGAATTATTTATTGATCAATGTAATCTAATAATAAGTAAACAGATCACTGGCGATGCGATACCAGTACTAAAACCGGTACCCTGTCTAAAGTTAATCGAGGATGTTGAAGATGAAAATGACAATCAAAAAGGTGATGACAAACAGGAACCAAATGAAACAAATCCTCAAGTGGATATATTACCATTACCACAACTTCAAAAACTTTTATTAACCGCTTTGCCTAAAACGAGGGTTAAAATCTTGAAGATCCCTTTCCATGCTACGTGGCGACAAAGCATTTCAGATACTGCTACACAATAG
Protein Sequence: MDGINVNGGNADGAREDPNLEAGSMPNLQETQVKVDTSKMDGQDVNGDIRNSPKKGRKRKLSEPDDLSSEESMEFNGFDIQGDNEVEPASHVLKKLIAEAEVAEAQLAKRFRYSIRKNFDTKKDDEDSDDNRMHDSEHVLDIDKVKKEKESDKSETESLGMPNTVESETEVQKTDDTSLKSTNSSSAASSPATSIKSKGYRLLRGVSPGSTGKQKVSSDISNPAFKEPFKYGWRRELVFRASNDSSLKRMADIYYYTPKGKKVRSFREVAEFLNTKELTIDNFTFLKEPIGPDDPEKEIIRDAKRMRGPGISATPPRKSIGYKRGTPGKRVIEEPASVPVPVATKATTKSPKAASTGFKVKVSAKKTPHITEIKSPSQEREILPPQRTTSTRRSQLPVEKPPPPKPKRQLTPKVQEPCSIRCSTSMGLIPSLQCRVCLCLYHPECVGGTEFAGSDNYVCKNCQQDTNESHQSQTNPSLTPPPLIPISMLGAQNTKSKHQVNLSPPKLQRIPKSDNADSQSRNATKILKTSSATSHSPLNSDNKESSWFAQTENEFLQSHDGILPKPAQNIALMGGKRYIVVPKNNAMAVQPAITVKPDKIGDKPPILQDGTLTDISNAVDNSMSTKARTSLTTKFVEKDAFDKSIDKDMSKDASHTGLPPSSIIEKANETCNSNDRTDILTATKSQNDLSSTTDLAIESKKSENCNTVEKKSIVKNSNTTNTNNDLFKVDTQHFVTSSLGTVKISSKRKQNRQDKEQQQHFMDSVCAGYHALLRIFQYLKVQELLRAARVCKMWRDLAAHPSLWKTVRMKNSQVTDWDGLADTLQRHGTQHLDLRKMLVAGESDSIWEKFLVVIPRVTSLVKLELCKCPVMVVEEVIRSCPQLEVLSAMSIKCDSLNLESVGNLKRCQELRLKAISGMSLKEDLTPLQELTQLTQLSLTSVKELGKKGINIIQALVNLETLELGECSDFPDKFGTTVLIKLQKLERLRLEKGQGSCCTFDILEGVSKLQNLSQMELVNFDVKNGFDKCLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSNNLTHFVWGVTLELLRVTELFIDQCNLIISKQITGDAIPVLKPVPCLKLIEDVEDENDNQKGDDKQEPNETNPQVDILPLPQLQKLLLTALPKTRVKILKIPFHATWRQSISDTATQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01065571;
90% Identity: iTF_00229354;
80% Identity: -