Basic Information

Insect: Bombus lapidarius
Gene Symbol: Rreb1
Assembly: GCA_936014575.1
Location: CAKXZU010000001.1:5006098-5012484[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0079 0.55 10.7 0.2 1 23 60 82 60 82 0.96

2 16 0.00032 0.022 15.1 0.4 1 23 96 118 96 118 0.97

3 16 7.7e-07 5.4e-05 23.3 1.2 1 23 124 147 124 147 0.98

4 16 0.011 0.79 10.2 0.0 1 23 242 266 242 266 0.95

5 16 0.07 4.9 7.7 3.0 2 23 272 294 272 294 0.95

6 16 1.8 1.3e+02 3.2 0.6 1 19 350 368 350 370 0.89

7 16 0.52 36 5.0 0.1 1 23 483 505 483 505 0.96

8 16 2.8e-05 0.0019 18.4 0.3 1 23 514 536 514 536 0.98

9 16 0.0012 0.085 13.2 2.8 1 23 542 565 542 565 0.97

10 16 0.00044 0.031 14.6 3.0 1 23 949 972 949 972 0.97

11 16 0.00064 0.045 14.1 0.1 3 23 1249 1269 1247 1269 0.97

12 16 0.57 40 4.8 6.0 1 23 1275 1298 1275 1298 0.97

13 16 0.004 0.28 11.6 2.2 1 23 1336 1360 1336 1360 0.97

14 16 6.2 4.4e+02 1.6 7.4 1 23 1444 1467 1444 1467 0.96

15 16 0.011 0.76 10.2 0.4 2 23 1518 1539 1517 1539 0.94

16 16 1.3 90 3.7 8.2 1 23 1545 1567 1545 1567 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0079	0.55	10.7	0.2	1	23	60	82	60	82	0.96
2	16	0.00032	0.022	15.1	0.4	1	23	96	118	96	118	0.97
3	16	7.7e-07	5.4e-05	23.3	1.2	1	23	124	147	124	147	0.98
4	16	0.011	0.79	10.2	0.0	1	23	242	266	242	266	0.95
5	16	0.07	4.9	7.7	3.0	2	23	272	294	272	294	0.95
6	16	1.8	1.3e+02	3.2	0.6	1	19	350	368	350	370	0.89
7	16	0.52	36	5.0	0.1	1	23	483	505	483	505	0.96
8	16	2.8e-05	0.0019	18.4	0.3	1	23	514	536	514	536	0.98
9	16	0.0012	0.085	13.2	2.8	1	23	542	565	542	565	0.97
10	16	0.00044	0.031	14.6	3.0	1	23	949	972	949	972	0.97
11	16	0.00064	0.045	14.1	0.1	3	23	1249	1269	1247	1269	0.97
12	16	0.57	40	4.8	6.0	1	23	1275	1298	1275	1298	0.97
13	16	0.004	0.28	11.6	2.2	1	23	1336	1360	1336	1360	0.97
14	16	6.2	4.4e+02	1.6	7.4	1	23	1444	1467	1444	1467	0.96
15	16	0.011	0.76	10.2	0.4	2	23	1518	1539	1517	1539	0.94
16	16	1.3	90	3.7	8.2	1	23	1545	1567	1545	1567	0.98

Sequence Information

Coding Sequence: ATGATATCGTTCTCGGAAGTTTGCTCCAACGGTAGCTTGCAGAATAGAAAAGACTTGGTAAATAAGGACGATTGTGGTTCAATTACTGTTAAGAACGGACCCACCCAGGAAAATGAGAACGAAGCACCAGCTGATGCTGCATCCTCACCATCTAGTGTTGAACTACCAGAAAGCGCACACCCATGTCCAGCTTGTTCGACCGTTTTGCCCACCTCCAGGGAGTTAACGAACCACTTACGCGGCCATAATTCGCCTCGCAGCACAGACTGTAGCGGCGAGGATGACTATTGCTGCGGCGTGTGCAATAAGGTGCTGAGCTCTGCAAGTTCCCTCGACAGACATGTGTTGGTGCACTCCGGGGAACGGCCGTTCAAATGCAAGTACTGTGAGATGGCGTTCACCACGAACGGCAATATGAACAGGCATTTGAGGACAGCGCACAGAGGCGCCTCGCCTAACAGCTGTACCGACTCCGAGGGTAGCAGCGACTCGGACAAATCATCCAGGCAGCGACATCTCGAGGAATACAACAACAACGAGATTACAAAAAGAAACTCGCCAAATATCGGAGACAAACGGGACGAGGAACAGACCTCGTCGTTAACTGGAAAGAGAAAGTGCCCTAACTATGTGAGCGACAGCGAAACACAAAAGAGGCACAAGATTCTTTTAAATAGCTCGAGAAGCGAGATGAAATCGAGACCGGATGACAACCAGAATATTTACAATTGTCCAGTATGCGGGCGACAAGATTTTGCCACTAGCGCCCTCTTAGAAGCGCATCTGGAACGAAGTCATCCGGAATTCCCGGCGAAATGCGACACGTGCAACTTGTCGTTCAAAAACCACAGAGTACTGAATCTGCATCGGTTCATGATACATTTCGCGGAACACTCGATGGGAAATACCGCGAGAAATCTGAGAAACTCGATAGTAGGTTTCAACGATTTAACGTTCGTTGATTTCTCGTCCGATAAGTTCCCAGCAATAGCAAGAGCTGTCTGCGAACAATCGCTTCACCGGCCAGCTTCTGGCGAGGTAGCCAAATTCCAATGCTCCAAATGTCTGCGAGCATTCCCTTGTAGATCCGCGTTGGACGCCCACGAAACTGACTGCGGCACGATGAATTTGCAAAGCAGAACAACCGACGATAGCCAATCGAGAAGAGACGATTTCTTCGCTGGCTTGGATCTTCAAAACAAGGCTGCTTTGAGGGAAGCGAAGGAAGGTAAAGATCTTGCCGATATCCAGAGTATCATATCTGTCACCTCTGGACCTATCTTACAGAGTTTTCGATCAGACACCAGTACACCCGAGAACAACATCAAATTTAATACCAGTGTAAATTCTTCTGGTAGTTCAAGTACGTATTGCGCAGAGTATCACGAGGAGGAAGCTCAAGACGCGTTTTCCGCGGAGTTCAGAAAAATGAAATTGAAAGGGGAGTTCCCTTGCAGGCTCTGTTCCTCGATATTTCCTAATCTAAGAGCCCTAAAAGGTCACAACAGGGCGCACATGGGCGTGGGACCTGGCATGCCATATCCTTGTAATATGTGCCCTTATACCAGCACTGATAAAGCGACTCTGGTGAGGCATCTGAGGTCTCACAATGGCGACAGACCTTACGAATGCTCTCTCTGCAATTACGCTTTCACAACTAAAGCAAATTGTGAGCGCCATGTACGAAACCGACATGGAAAATTGACAAGAGAAGACATTAAGAGCGTTCTCATCTATCATCCAAATGAAGATTCTACGAACGAGAACGTGGAACGTGGAAACTCACCCAGAGTTTTGAAAGATGAAGTGAGGAAGAGCCTGGTATATCCGCCAGAACGCGAAGATCTTCACCACCAGGCCCAAATACATTATCCTCCGGTTTCTATGGAGGTAAGAGGTGAGATCAGAATAATAGAAGAGGCGAAGCTGCAAAATTCCTCGATGTCGATATACAGCACTAGCCACTTTGAAAAAAATGATGCGTTTTCAAGGCATGGTCAGCCTTTGGAGCTGACCCAAAGGAACTCCGAGGAGACAAAACCTGGTCAAGATGCCAAATCGGATTATTCGAAGTTGGACGACGATTTGGAGTCGAGATCATCCGAGGGTAGCGTATCTCTAGTCACAGAAACCAAAACAGATTCGCACCAAAGAATACAAGCTAGTCCTATGAATTTAAAGAAAGGTCTCAACATATCGGAAAACGTAGGCGAAGACGGTCCGTTGGACCTTTCCATGGACGTACTGGATCTCAGCAAGAAGTCGAAGGAGAAGGAGAACGATAACTTCGCCGCGGCTCACGAACAATTTGGAAAAAACCAAAAAGATTTGTACAGTGCTACCAGTCAATTATTGTTGACCGAGGCTTTGTTGAAGGCTGGCCAGGGTAGCTCTCAACCTACATCTACATCTCTGGAAGCTCTGTACGCTAACGCGATCTACAGAAACTTCAGTACATTCCCTGGTAGCGTAGGAGCTGGAATATTGCCACCGTACATGTTCAATCCTCATGTCTTTGGCCAGGATTTCTCTATGAAGGAAAGATTACAGAAGGAATTGGTCAGAGGTCTACAGTTGACAAGTGGAGGTACTTTGGTGGAGCCACCCATAGGTAGCGCGGGATTTACCACCTTTTCTCAAAATAGAGACATGAATTCCCAGTCTCATTCAACAACCGACCAAAGTGAATATGCCAAATTAATATCTTCTAAGATGGCCAACAAGAGTCTGACAGCCCGCGATAAACCGGACAATCTGCCCTCGTCCAATTCTGTGAAGATGGTGATCAAAAATGGAGTCCTGATGCCTAAACAAAAGCAGCGAAGGTACAGAACCGAGAGGCCTTTTACCTGTGAACATTGCTCAGCGAGATTTACCTTGAGGAGCAATATGGAAAGGCATATTAAACAACAACATCCTCAGCACTGGAGCCAGCGACCCAGAGGAGGTCACTCGACAAGGGGAAGACCACCTTCCAGCCATCCTACGCTGATTCAAAACCTTGGACAGGCAACTACTCAAGGCAGTCAATCGTATAACAACATCCTGCCAAAAGTGGAACAGTCGACGAATCCGGAATTTACGAGGCACTCTATCTCCGACCAAGTGAAGTACGCTATCCTGGCACAGCAATTAAAGGCAAACAAAGTGGAAGACAATGACTCTGAAGAAGAACTGGTCATAGACGAAGGGCCACAGGAGAAAGAAAATCAAGAATCTCAGGATCAAAGGGAGAAGAGTCTGTTGAGAGGACAATTGGAAGCTACAGAATCTACGAAAGAAATTGTAGTGAAGGAAGAACCCATGGAATGTTCAAACGATGGCCAAAACGAGACAAATGTTGAGCTGGAGAAGAACGAACAAACTGTTACTGAACAACAGAAAAAATCTAACACGGAGAAGGCTATTGTCACGGAAAATTCGGTTGAAAAGAATCCTGACAGAGTGCTCAAAACGGAATCAGTTAATATGAACAACGTGAAGATGGAGGATGGAGCACCTGATCTCGCTAGCGTATCAGAACTGTTAGACAATGCCTCCCAACAATACCAGCAGTTTCAACCCCAGTATTTAAGCGATGAAGAAGGACTAGTAGCATCGAACAGTGATTGCAATAATTCTGGCAGTGATGAGAAATCCGACTCTGTAAATTCATCACATTCGACGAACGCGTCGAAAAAAAAGAAGAAAAAGAAGAAAAAAAAGAAGAAATCAGCATATTCAATGGCGCCGAACAGAGTAATCTGTCCATACTGTGAACGACCATTTCCATGGACCTCGTCTCTCAGACGACATATTTTGACACACACTGGACAGAAACCTTATCAATGCGTTCACTGTTCATTGCTATTCACAACAAAATCCAACTGCGACCGTCATCTGCTCCGAAAACATAAAGCAAATCCGAACAAGATGCGTAGAGTAAGAAACTCTTCTTCTCCAGATTCTCAGGCGGTCATCAACAATAGTAACTCGTTCTCCATGAGGAACGTTCCTGAAAGACCCTACAAGTGCAATCAGTGTCCCAGCTCAACATTTTCGACGTTGGGTAACCTAAAGAAACATCGTTCCACTAAACACGCTCGGAAGATGAAGACCAGGTCGGACACTCCATCCAGTGAACCTCAAACAAGCCCACAGGAGTGTCCAAAGCCGAATAACGAACAAACTGATTATGATAGTCAGTCTTCGAGCGTGTCTGAAGGGATAGAAACTTCTTCGATGCCAGGGCTTACTAAATCGAATTCTAACGTTTCACAATTGGCCAACGAAACAGCTAGGTCAAGGAGACCTTCGCCGAGATCATCACCTGGGCCCAGTGATGTGCCTTTTAAGTGCCACTTGTGCGATTGTGGTTTCGCAGAACGACACGACTGCCTCGAACACATCAAAATGAACCACAAAAAATCCTACGAAATGTTAGTGGCGAAAGGGGCACTGGACATGGACATCGACGCGGTTGAAGACCAACAACAGCAACCGCCCCAACATCATACCAGCGACGGAGAAGAAAAACGGGGACGTTTCCCAGACTATAGTAACAGAAAGGTTGTATGTGCATTCTGTATGAGGCGGTTCTGGTCTGCAGAGGATCTCCGGCGGCATATGAGAACACACACCGGAGAACGACCTTTCTCCTGCGATATATGCTGCAGAAGATTCACCTTGAAACATAGTATGCTGCGGCACAGAAAGAAGCACGAGTCCATTGATTCTACCATGTATGTTGGTACAAGCGGAGACGAAGAAAATTCACCTGCACAGCCACCTACGATCACACCACGAAGTCAACAACAACAACAAATTCTGGTGACAGCCAACAACGGAAATTCCCGTATTCAAGACAGAATCTCTTTACCAACTGTTACTCCAGTCGCGACCGGTGATGCAGCCCCGAGTGGATTGATAAGATTCAATCCATACGAGAAATTAACCACTCTGACAGGAAAATTGGCCAGTATTCCATCAAACGCAAATCCAGATGCAGAGAGCACGGATAATGATTTGATCTCGAACCTGCTGGGAATAAGAGACAAGAGTTTCATCGACAGAGTACTACAGGCATCCGCTGATGACGCCGCCAAGCTATTAGGAGTAAAGCGTAGCCATGAGTGA
Protein Sequence: MISFSEVCSNGSLQNRKDLVNKDDCGSITVKNGPTQENENEAPADAASSPSSVELPESAHPCPACSTVLPTSRELTNHLRGHNSPRSTDCSGEDDYCCGVCNKVLSSASSLDRHVLVHSGERPFKCKYCEMAFTTNGNMNRHLRTAHRGASPNSCTDSEGSSDSDKSSRQRHLEEYNNNEITKRNSPNIGDKRDEEQTSSLTGKRKCPNYVSDSETQKRHKILLNSSRSEMKSRPDDNQNIYNCPVCGRQDFATSALLEAHLERSHPEFPAKCDTCNLSFKNHRVLNLHRFMIHFAEHSMGNTARNLRNSIVGFNDLTFVDFSSDKFPAIARAVCEQSLHRPASGEVAKFQCSKCLRAFPCRSALDAHETDCGTMNLQSRTTDDSQSRRDDFFAGLDLQNKAALREAKEGKDLADIQSIISVTSGPILQSFRSDTSTPENNIKFNTSVNSSGSSSTYCAEYHEEEAQDAFSAEFRKMKLKGEFPCRLCSSIFPNLRALKGHNRAHMGVGPGMPYPCNMCPYTSTDKATLVRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLTREDIKSVLIYHPNEDSTNENVERGNSPRVLKDEVRKSLVYPPEREDLHHQAQIHYPPVSMEVRGEIRIIEEAKLQNSSMSIYSTSHFEKNDAFSRHGQPLELTQRNSEETKPGQDAKSDYSKLDDDLESRSSEGSVSLVTETKTDSHQRIQASPMNLKKGLNISENVGEDGPLDLSMDVLDLSKKSKEKENDNFAAAHEQFGKNQKDLYSATSQLLLTEALLKAGQGSSQPTSTSLEALYANAIYRNFSTFPGSVGAGILPPYMFNPHVFGQDFSMKERLQKELVRGLQLTSGGTLVEPPIGSAGFTTFSQNRDMNSQSHSTTDQSEYAKLISSKMANKSLTARDKPDNLPSSNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPSSHPTLIQNLGQATTQGSQSYNNILPKVEQSTNPEFTRHSISDQVKYAILAQQLKANKVEDNDSEEELVIDEGPQEKENQESQDQREKSLLRGQLEATESTKEIVVKEEPMECSNDGQNETNVELEKNEQTVTEQQKKSNTEKAIVTENSVEKNPDRVLKTESVNMNNVKMEDGAPDLASVSELLDNASQQYQQFQPQYLSDEEGLVASNSDCNNSGSDEKSDSVNSSHSTNASKKKKKKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCVHCSLLFTTKSNCDRHLLRKHKANPNKMRRVRNSSSPDSQAVINNSNSFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHARKMKTRSDTPSSEPQTSPQECPKPNNEQTDYDSQSSSVSEGIETSSMPGLTKSNSNVSQLANETARSRRPSPRSSPGPSDVPFKCHLCDCGFAERHDCLEHIKMNHKKSYEMLVAKGALDMDIDAVEDQQQQPPQHHTSDGEEKRGRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKHESIDSTMYVGTSGDEENSPAQPPTITPRSQQQQQILVTANNGNSRIQDRISLPTVTPVATGDAAPSGLIRFNPYEKLTTLTGKLASIPSNANPDAESTDNDLISNLLGIRDKSFIDRVLQASADDAAKLLGVKRSHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00625690;
90% Identity: iTF_00220802; iTF_00233459; iTF_00216599; iTF_00217300; iTF_00221468;
80% Identity: -