Basic Information

Insect: Bombus hortorum
Gene Symbol: Rreb1
Assembly: GCA_905332935.1
Location: HG995194.1:7589340-7596576[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.003 0.32 11.8 0.0 1 23 39 61 39 61 0.98

2 15 0.0057 0.61 10.9 1.2 1 20 75 94 75 100 0.93

3 15 0.0094 1 10.2 0.0 1 23 195 219 195 219 0.95

4 15 0.059 6.3 7.7 3.0 2 23 225 247 225 247 0.95

5 15 1.5 1.6e+02 3.3 0.6 1 19 303 321 303 323 0.89

6 15 0.43 46 5.0 0.1 1 23 436 458 436 458 0.96

7 15 2.3e-05 0.0025 18.5 0.3 1 23 467 489 467 489 0.98

8 15 0.001 0.11 13.3 2.8 1 23 495 518 495 518 0.97

9 15 0.00037 0.04 14.7 3.0 1 23 901 924 901 924 0.97

10 15 0.00054 0.057 14.2 0.1 3 23 1201 1221 1199 1221 0.97

11 15 0.48 51 4.9 6.0 1 23 1227 1250 1227 1250 0.97

12 15 0.0034 0.36 11.6 2.2 1 23 1288 1312 1288 1312 0.97

13 15 5.2 5.6e+02 1.6 7.4 1 23 1396 1419 1396 1419 0.96

14 15 0.0091 0.97 10.3 0.4 2 23 1470 1491 1469 1491 0.94

15 15 1.1 1.2e+02 3.8 8.2 1 23 1497 1519 1497 1519 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.003	0.32	11.8	0.0	1	23	39	61	39	61	0.98
2	15	0.0057	0.61	10.9	1.2	1	20	75	94	75	100	0.93
3	15	0.0094	1	10.2	0.0	1	23	195	219	195	219	0.95
4	15	0.059	6.3	7.7	3.0	2	23	225	247	225	247	0.95
5	15	1.5	1.6e+02	3.3	0.6	1	19	303	321	303	323	0.89
6	15	0.43	46	5.0	0.1	1	23	436	458	436	458	0.96
7	15	2.3e-05	0.0025	18.5	0.3	1	23	467	489	467	489	0.98
8	15	0.001	0.11	13.3	2.8	1	23	495	518	495	518	0.97
9	15	0.00037	0.04	14.7	3.0	1	23	901	924	901	924	0.97
10	15	0.00054	0.057	14.2	0.1	3	23	1201	1221	1199	1221	0.97
11	15	0.48	51	4.9	6.0	1	23	1227	1250	1227	1250	0.97
12	15	0.0034	0.36	11.6	2.2	1	23	1288	1312	1288	1312	0.97
13	15	5.2	5.6e+02	1.6	7.4	1	23	1396	1419	1396	1419	0.96
14	15	0.0091	0.97	10.3	0.4	2	23	1470	1491	1469	1491	0.94
15	15	1.1	1.2e+02	3.8	8.2	1	23	1497	1519	1497	1519	0.98

Sequence Information

Coding Sequence: ATGGACGACGCACGACGCTTTACTGTTAAGAACGGACCCACCCAGGAAAATGAGAACGAAGCACCAGCTGATGCTGCATCCTCACCATCTAGCGTTGAACTACCAGAAAGCGCGTACCCATGTCCAGCTTGTTCGACCGTTTTGCCCACCTCCAGGGAGTTAACGAACCACCTACGCGGCCATAATTCGCCTCGCAGCACAGACTGTAGCGGCGAGGATGACTATTGCTGCGGCGTGTGCAATAAGGTGCTGAGCTCTGCAAGTTCCCTCGACAGACATGTGCATTTGAGGACAGCGCACAGAGGCGCCTCGCCCAACAGCTGCACCGACTCCGAGGGTAGCAGCGACTCGGACAAATCATCCAGGCAGCGACATCTCGAGGAATACAACAACAACGAGATCACAAAAAGAAACTCGCCAAATATCGGGGACAGACGGGACGAGGAACAGACCTCGTCGTTAACTGGAAAGAGAAAGTGCCCTAGCTATGCGAGCGACAGCGAAACACAAAAGAGGCACAAGATCCTTCTAAATAGTTCGAGGAGCGAGATGAAATCGAGACCGGATGACAACCAGAACATTTACAATTGTCCAGTATGCGGGCGACAGGATTTTGCCACTAGCGCCCTCTTAGAGGCGCATCTGGAACGAAGTCACCCGGAATTCCCTGCGAAATGTGACACGTGCAACCTGTCGTTCAAAAACCACAGAGTACTGAATCTGCATCGGTTCATGATACATTTCGCGGAACACTCGATGGGAAATACCGCGAGAAATTTGAGAAACTCGATAGTAGGTTTCAACGATTTAACGTTCGTTGATTTCTCGTCCGACAAGTTCCCAGCAATAGCGAGAGCTGTCTGCGAACAATCGCTTCACCGGCCAGCTTCTGGCGAGGTAGCCAAATTCCAATGCTCCAAATGTCTGCGAGCATTCCCTTGTAGATCGGCGTTGGACGCCCACGAAACTGACTGCGGCACGATGAATTTGCAAAGCAGAACAACCGACGATAGCCAATCGAGAAGAGACGATTTCTTCGCTGGCTTGGATCTTCAAAACAAGGCTGCTTTGAGGGAAGCGAAGGAAGGCAAAGATCTTGCCGATATCCAGAGCATCATATCTGTCACCTCTGGACCTATCTTACAGAATTTCCGATCAGACGCCAGTACACCCGAGAACAACATCAAATTTAACGCCAGTATAAACTCTTCTGGTAGTTCAAGTACGTATTGCGCGGAGTACCACGAGGAGGAAGCTCAAGACGCGTTTTCTGCGGAGTTCAGAAAAATGAAATTGAAAGGGGAGTTCCCTTGCAGGCTCTGTTCCTCGATATTTCCTAATCTAAGAGCCCTAAAAGGTCACAACAGGGCGCACATGGGCGTGGGACCTGGCATGCCGTATCCTTGTAATATGTGCCCTTATACCAGCACTGATAAAGCGACTCTGGTGAGGCATCTGAGGTCTCACAATGGCGACAGACCTTACGAATGCTCTCTCTGCAATTACGCTTTCACAACTAAAGCAAATTGTGAGCGCCATGTACGAAACCGACATGGAAAATTGACAAGAGAAGACATTAAGAGCGTTCTCATTTATCATCCAAACGAAGATTCTACGAACGAGAACGTGGAACGTGGAAACTCACCCAGAGTTTTGAAGGATGAAGTGAGGAAGAGCCTGGTATATCCGCCAGAACGCGAAGATCTTCACCACCAGGCGCAGATACATTATCCGCCGGTTCCAATGGAGGTAAGAAGCGAGATCAGAATAATAGAAGAGGCGAAGCTGCAAAATTCCTCGATGTCGATGTACAGCACTAGCCACTTTGAAAAAAATGATGCGTTTTCAAGGCATAGCCAGCCTTTGGAGCTGACCCAAAGGAACTCCGAGGAGACAAAAGCTGGTCAAGATGCCAAATCGGATTATTCGAAGTTGGACGACGATTTGGAGTCGAGGTCGTCCGAGGGTAGCGTATCTCTAGTCACAGAAACCAAAACAGATTCGCACCAAAGAATACAAGCTAGTCCTATGAATTTAAAGAAAGGTCTCAACACATCGGAAAACATAGGCGAAGACGGCCCGTTGGACCTATCCATGGACGTACTGGATCTCAGCAAGAAGTCGAAGGGGAAGGAGGACGATAACGAGGTCGCCGCGGCTCACGAACAATTTGGAAAAAACCAAAAAGATTTGTACAGTGCTACCAGCCAATTATTGTTGACCGAGGCTTTGTTGAAGGCTGGCCAGGGTAGCTCTCAACCCACATCTCTGGAAGCTCTGTACGCTAACGCGATCTACAGAAACTTCGGTACATTCCCTGGTAGCGTAGGAGCTGGAATACTGCCACCGTACATGTTCAATCCTCATGTCTTTGGCCAGGATTTCTCTATGAAGGAAAGATTACAGAAGGAATTGGTCAGAGGTCTACAGTTGACAAGCGGAGGTACTTTGGTGGAGCCACCCATAGGTAGCGCGGGATTTACCACCTTTTCCCAAAATAGAGACATGAATTCCCAGTCTCATTCAACAGCCGACCAAAGTGAATATGCCAAATTAATATCTTCTAAGATGGCCAACAAGAGTCTGACAAACCGCGATAAACCAGACAATCTGCCCTCGTCCAATTCTGTGAAGATGGTGATCAAAAATGGAGTCCTGATGCCTAAACAAAAGCAACGAAGGTACAGAACTGAGAGGCCCTTCACCTGTGAACATTGCTCAGCGAGATTTACCTTGAGGAGCAATATGGAAAGGCACATTAAACAACAACATCCTCAGCACTGGAGCCAGCGACCCAGAGGAGGTCACTCGACAAGGGGAAGACCACCTTCGAGCCATCCTACGCTGATTCAAAACCTAGGACAGGCAACTTCTCAAAGCAGTCAGTCGTACAACAACATCCTGCCAAAAGTGGAACAGTCAACGAATCCGGAATTTACGAGGCATTCCATCTCCGACCAAGTGAAGTACGCTATCCTGGCACAGCAATTAAAGGCAAACAAAATGGAGGACAACGACTCTGAAGAAGAACTGGTAATAGACGAAGGGCCCCAGGAGAAAGAAAATCAAGAATCTCAGAATCAAAGGGAGAAGAGTCTGTTGAGAGGGCAATTGGAAGCTACAGAATCTACGAAAGAAATTGTAATAAAAGAAGAAGTCATGGAATGTTCAAACGATGACCCAAACGAGACAAATGTTCAGCTGGAGACGAACGAACAAACTGTTACTGAACAACAGAAAAAATCTGAAACGGAGAAGGCTACTGTGACGGAAAATTCTGTCGATAAGAACGTTGACAGAGTGCTCAAAACGGAATCAGTTAATATGAAAAGCGAGAAAATGGAGGATGCAGCAACCGATCTCGCTAGCGTGTCAGAACTGCTAGATAATGCATCCCAACAATACCAACAGTTTCAACCCCAGTATTTAAGCGACGAAGAAGGCCTAGTAGCATCGAACAGTGATTGCAATAATTCTGGCAGTGATGAGAAATCCGACTCTGTAAATTCATCACATTCGACGAACGCGTCAAAGAAAAAGAAGAAAAAGAAGAAAAAAAAGAAGAAATCGGCGTATTCAATGGCCCCGAATAGAGTAATCTGTCCATACTGTGAAAGACCATTTCCATGGACCTCGTCTCTCAGACGACATATTTTAACACACACCGGACAGAAACCATATCAATGCGTTCACTGTTCCTTGCTATTCACAACGAAATCCAACTGCGACCGTCATTTGCTCCGAAAACATAAAGCAAATCCGAACAAGATGCGTAGAGTTAGAAACTCTTCTTCTCCGGATTCTCAAGCGGTCATCAACAATAGTAACTCGTTCTCCATGAGGAACGTTCCCGAAAGACCCTACAAGTGCAATCAGTGTCCCAGCTCAACATTTTCAACGTTGGGTAACCTAAAGAAACATCGTTCCACTAAACACGCTCGGAAGATGAAGACCAGGTCGGACACTCCATCCAGTGAACCTCAAACTAGCCCGCAGGAGTGTCCAAAGCCGAATAACGAACAAACTGATTACGATAGTCAGTCTTCGAGCGTGTCCGAAGGGATAGAAACTTCTTCGATGCCAGGGCTTACCAAATCGAATTCTAACGCTTCACAATTGGCCAACGAAACAGCTAGGTCAAGGAGACCTTCGCCGAGATCATCACCTGGACCCAGTGATGTTCCTTTCAAGTGCCACTTGTGCGACTGTGGTTTCGCAGAACGACACGACTGCCTCGAACACATCAAAATGAACCACAAAAAGTCCTACGAAATGTTAGTGGCGAAAGGGGCATTGGACATGGACATCGACGCGGTTGAAGACCAGCAACAACCGCCGCCACAACATCATACCAGCGACGGGGAAGAAAAACGGGGACGTTTCCCAGACTATAGTAACAGGAAGGTTGTATGTGCATTCTGTATGAGGCGGTTCTGGTCTGCAGAGGATCTCCGGCGTCATATGAGAACACACACTGGGGAACGACCTTTCTCCTGCGATATATGCTGCAGAAGATTCACCTTGAAACATAGTATGCTGCGGCACAGAAAGAAGCACGAGTCCATTGATTCTACCATGTATGTAGGTACAAGCGGAGACGAAGAAAACTCACCTACACAGCCACCTACGATCACACCACGAAGTCAACAGCAGCAACAAATTCTGGTGACAGCCAACAACGGAAATTCCCGTATTCAAGACAGAATCTCTTTACCAACTGTTACTCCAGTCGCGACCGGTGATGCAGCCCCCAGTGGATTAATAAGATTCAATCCATACGAGAAATTAACCACTCTGACAGGAAAATTGGCCAGTATTCCATCAAACGCAAATCCAGACGCAGAGAGCACGGATAATGATTTGATCTCGAACCTGCTGGGAATAAGAGACAAGAGTTTCATCGACAGAGTACTGCAGGCATCCGCTGATGACGCCGCCAAGCTATTAGGAGTAAAGCGTAGCCATGAGTGA
Protein Sequence: MDDARRFTVKNGPTQENENEAPADAASSPSSVELPESAYPCPACSTVLPTSRELTNHLRGHNSPRSTDCSGEDDYCCGVCNKVLSSASSLDRHVHLRTAHRGASPNSCTDSEGSSDSDKSSRQRHLEEYNNNEITKRNSPNIGDRRDEEQTSSLTGKRKCPSYASDSETQKRHKILLNSSRSEMKSRPDDNQNIYNCPVCGRQDFATSALLEAHLERSHPEFPAKCDTCNLSFKNHRVLNLHRFMIHFAEHSMGNTARNLRNSIVGFNDLTFVDFSSDKFPAIARAVCEQSLHRPASGEVAKFQCSKCLRAFPCRSALDAHETDCGTMNLQSRTTDDSQSRRDDFFAGLDLQNKAALREAKEGKDLADIQSIISVTSGPILQNFRSDASTPENNIKFNASINSSGSSSTYCAEYHEEEAQDAFSAEFRKMKLKGEFPCRLCSSIFPNLRALKGHNRAHMGVGPGMPYPCNMCPYTSTDKATLVRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLTREDIKSVLIYHPNEDSTNENVERGNSPRVLKDEVRKSLVYPPEREDLHHQAQIHYPPVPMEVRSEIRIIEEAKLQNSSMSMYSTSHFEKNDAFSRHSQPLELTQRNSEETKAGQDAKSDYSKLDDDLESRSSEGSVSLVTETKTDSHQRIQASPMNLKKGLNTSENIGEDGPLDLSMDVLDLSKKSKGKEDDNEVAAAHEQFGKNQKDLYSATSQLLLTEALLKAGQGSSQPTSLEALYANAIYRNFGTFPGSVGAGILPPYMFNPHVFGQDFSMKERLQKELVRGLQLTSGGTLVEPPIGSAGFTTFSQNRDMNSQSHSTADQSEYAKLISSKMANKSLTNRDKPDNLPSSNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPSSHPTLIQNLGQATSQSSQSYNNILPKVEQSTNPEFTRHSISDQVKYAILAQQLKANKMEDNDSEEELVIDEGPQEKENQESQNQREKSLLRGQLEATESTKEIVIKEEVMECSNDDPNETNVQLETNEQTVTEQQKKSETEKATVTENSVDKNVDRVLKTESVNMKSEKMEDAATDLASVSELLDNASQQYQQFQPQYLSDEEGLVASNSDCNNSGSDEKSDSVNSSHSTNASKKKKKKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCVHCSLLFTTKSNCDRHLLRKHKANPNKMRRVRNSSSPDSQAVINNSNSFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHARKMKTRSDTPSSEPQTSPQECPKPNNEQTDYDSQSSSVSEGIETSSMPGLTKSNSNASQLANETARSRRPSPRSSPGPSDVPFKCHLCDCGFAERHDCLEHIKMNHKKSYEMLVAKGALDMDIDAVEDQQQPPPQHHTSDGEEKRGRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKHESIDSTMYVGTSGDEENSPTQPPTITPRSQQQQQILVTANNGNSRIQDRISLPTVTPVATGDAAPSGLIRFNPYEKLTTLTGKLASIPSNANPDAESTDNDLISNLLGIRDKSFIDRVLQASADDAAKLLGVKRSHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00625690;
90% Identity: iTF_00222715;
80% Identity: -