Acus049193.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Arma custos
Gene Symbol
Hr39
Assembly
GCA_037127475.1
Location
CM073762.1:101301970-101322546[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.16 6.3e+03 -1.7 5.0 62 172 198 326 155 334 0.66
2 3 3.1e-08 0.0012 20.4 0.1 1 21 445 465 445 474 0.88
3 3 5.7e-70 2.2e-65 223.8 0.0 160 408 478 721 466 721 0.96

Sequence Information

Coding Sequence
ATGGAAGAAGGTCTAGAGGAAGATCTCGACATACCCGGGAAGAAGGTGTTAAAGAAAGCGACTAGAAATCTGGAATGGAACAGAAGATGGGAATTAGTGGAGGATCATAAAGTGTGGCCCGGGCTAGGAGGCAGGAGAAGCGAGGAGGCCCAGGGAGAGAAGACATCCTGCGATGGGGAGGTAGCACACGCTCAAGACATGGAGGGCGGTGTCAAATGCAGGCCCACTTCTGCTGGGGTGGTCCTTAGTCTCCGTCCCGCGGGCTCAAGCAGTGCATGTTCCGTTGTAGTAAGCAATGAACAAATGAATGTTGATGATGACTCATCAGCAGCTGATGCCGAAGTCAGCACCTTTACAAGTGAAACTGTTAACCTTAGGAATAGGCATGGAGAGGACCCGAGGCTACCGATGGAAAGGCCAATGTCTTGGGAGGGTGAGCTCTCTGATTCGGAGGTTGTCACAATCAAAccgGAGCCAGAAGATGTGGCCGATACGATAGACAATCAAAATTCTAGCAAGGGCAACCAAATGAAAGGGGATAGTGAAGTGCCTCAGCCTTTGAAACTGAACAACGAGACAATCAATGAAAAAGTTTTGGACCAAACAAGGACAAATCATATTAATGCTCAAACTGAGCTTCCTCTTCTAGTGGATAAGATTTTGaGTAGTGGCAACTATCTGAAAGGAGCTGGCCCAACGCCCAGCCCTGACTCCGCCGTGTACTCCTGCTACTCCCCGACAGCTAGTCCTgtcacctctcgccatatcttGTCTTCCTCCTCCGGGATTTCATCTCCATTCACGCCATCTTTATCGAGAAACAACAGTGATGCGTCGCAGTATGGTGGTTCTCAACATTCATCATGCTACAGTCacagttacTCATCGGTATCGGTCTCTCCGACCCAGTTCTCTCCGACTCACTCGCCGATCCAGGGTAGGCACATCCCAAGGCCAGGCTTTCCGTCACCTGTTCTCAACTCTAGGAGTGTCCATGACTATTCCATTCAAgATGATGGAAGTGTGCTTGAAGATAAATTCTCATCACTGACTGCTGATATGGTGCAGCATTCTGCTGGCCTCGCTTCACCTGGAATTAGCAGGCAGCAACTTATAAACAgcccCTGTCCTATTTGTGGAGATAAAATCTCAGGATTCCACTACGGCATCTTTTCCTGTGAGAGCTGTAAAGGATTCTTTAAAAGAACAGTACAGAATAGGAAAAACTACGTCTGCCTCAGGGGATCCTCTTGCCCTGTCACGATTGCGACAAGAAAGAAGTGTCCGGCGTGTAGGTTCGACAAGTGCTTAAACATGGGCATGAAGTTGGAAgCAATTAGGGAAGATCGAACACGAGGTGGCAGGAGTACCTACCAGTGCTCGTACACCGTACCAGCAGGTCTTGTAGAAACAAAGTGTTCAGATTTAAGGCCAGAACATGCTCAGCCGACATCACTCATTCCTCCCCTCCTTCAGGAAATCATGGAAGTAGAACACCTTTGGCAATACAACGAGGGGGAAGTGAGAGGTGGTGGTCGAGGAGGCCCTCAGAGCAGCGGAGGCAGCAACTCGACAGATCTCATGGCCAACCTCTGCAATATCGCTGACCATCGTCTCTACAAGATCGTCAAGTGGTGCAAGTCGCTTCCACTCTTCAAGAACATTTCTattGATGATCAGACTTCTCTCCTCATCAACGCTTGGTGCGAACTTCTCCTGTTCTCGTGCTGCTTCAGGTCAATGAGTTCTCCCGGGGAGATAAGGGTGTCCCTTGGCAAGTGCATTACGCTGCCAGAAGCCAGGACTCTTGGCCTGGGGCCGCCGATTGAACGGATGCTGAACTTCACGGAGCATCTGAGGCGGCTGAGGGTAGACCGTTACGAATATGTGGCTATGAAGGTCATCGTTCTCTTGTCTTCTGaCACGAGTGAATTAAGAGAACCAGAGAAGGTAAGAGCTTCCCAGGAGAAAGCGCTGCAAGCACTCCAGCACTACACTCTTGCCCATTATCCAGACATTCCGTCCAAGTTCGGAGAACTACTTCTTAGGATACCAGACCTACAAAGGACCTGCCAGgtTGGTAAAGAAATGCTTTCTATCAAAAGTAAAGAGGGAGAAGGACCCAGTTTCAATCTGCTCATGGAACTGTTGAGGGGTGACCACTGA
Protein Sequence
MEEGLEEDLDIPGKKVLKKATRNLEWNRRWELVEDHKVWPGLGGRRSEEAQGEKTSCDGEVAHAQDMEGGVKCRPTSAGVVLSLRPAGSSSACSVVVSNEQMNVDDDSSAADAEVSTFTSETVNLRNRHGEDPRLPMERPMSWEGELSDSEVVTIKPEPEDVADTIDNQNSSKGNQMKGDSEVPQPLKLNNETINEKVLDQTRTNHINAQTELPLLVDKILSSGNYLKGAGPTPSPDSAVYSCYSPTASPVTSRHILSSSSGISSPFTPSLSRNNSDASQYGGSQHSSCYSHSYSSVSVSPTQFSPTHSPIQGRHIPRPGFPSPVLNSRSVHDYSIQDDGSVLEDKFSSLTADMVQHSAGLASPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVTIATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTVPAGLVETKCSDLRPEHAQPTSLIPPLLQEIMEVEHLWQYNEGEVRGGGRGGPQSSGGSNSTDLMANLCNIADHRLYKIVKWCKSLPLFKNISIDDQTSLLINAWCELLLFSCCFRSMSSPGEIRVSLGKCITLPEARTLGLGPPIERMLNFTEHLRRLRVDRYEYVAMKVIVLLSSDTSELREPEKVRASQEKALQALQHYTLAHYPDIPSKFGELLLRIPDLQRTCQVGKEMLSIKSKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00373210;
90% Identity
iTF_01298468; iTF_00763919; iTF_01298415; iTF_00715153; iTF_00763893; iTF_00715193; iTF_00165309;
80% Identity
iTF_00165309;