Aaph013962.1
Basic Information
- Insect
- Aphidoletes aphidimyza
- Gene Symbol
- MBD2_1
- Assembly
- GCA_030463065.1
- Location
- CM059999.1:13988190-13989894[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.3e-21 1.3e-17 63.3 0.0 1 70 5 69 5 85 0.91 2 2 8.8e-05 0.22 11.3 0.0 28 73 126 184 96 187 0.80
Sequence Information
- Coding Sequence
- atgaatatcacaatcgaacgaaagaaaacaGATTGCAATGCACTGCCAAAGGGATGGCAACGCGAAGAGGTGCTTCGAAAAACTGGACTCTCGGCGGGCAAAGTGGATGTTTATTATTACAgCCCAAGTGGTGGTAAAGttgaaacaaaatcgaaactaGTGCGTCAGTTGGGCGAAACCATTGACCTTTCAACGTTTGATTATCAATCGGGTCGTCATCAAATGCTCaatacaaatccaaatttgTCTCCGTCTCCATCTCCATCTCAACCATCGAGCAGCAGTCAATCGATGGTAAATCCATTTCAACGAACTTCAATACGTCGTTCGATTCATGAATCACCAATGGGTCAACCTTCGCCTGTCGCATCAGGTGCATCAAGTCGTGGTGTTAGAACGGATGTTTCATTGGTGCCGCCGATTCGACAAACAGCATCCATATTCAAGCAACCGGTTACAGTTCATCGAAATCATGATTCCAAAGTGAAAAGTGACTTAAAACATGGCACATCACAAGAGAAGCCAAAACAACTATTCTGGGAGAAACGCTTAGAGgGATTACATGCATGTGACATGGATGGCAATGATTTTGGGCCAATTGAATTGCCACGTGGCTTGAAGCCGGTCGGGCCAAATGTCAACAATGGTACGTTGCTACAGTCGGTGACCACGGCATTGCACCTCAATAACACACAACCCATTACGGGGCAAACAGCATCCAAATCAGCTCTCACATCCAATGCAGGCGTCTTCTTGGATCCTGCACAACCACTTATGCATGCCGTCACAATCACCGATGATGACATTCGACGGCAAGAGGATCGTGTGACAAATGCACGCAAAAAACTACAAGATGCACTTAAATGCTGA
- Protein Sequence
- MNITIERKKTDCNALPKGWQREEVLRKTGLSAGKVDVYYYSPSGGKVETKSKLVRQLGETIDLSTFDYQSGRHQMLNTNPNLSPSPSPSQPSSSSQSMVNPFQRTSIRRSIHESPMGQPSPVASGASSRGVRTDVSLVPPIRQTASIFKQPVTVHRNHDSKVKSDLKHGTSQEKPKQLFWEKRLEGLHACDMDGNDFGPIELPRGLKPVGPNVNNGTLLQSVTTALHLNNTQPITGQTASKSALTSNAGVFLDPAQPLMHAVTITDDDIRRQEDRVTNARKKLQDALKC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01288132; iTF_00367216;
- 90% Identity
- iTF_00367216;
- 80% Identity
- -