Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.041 9.7e+02 -0.2 0.1 29 37 16 24 11 24 0.81

2 3 0.35 8.3e+03 -3.2 0.4 30 37 40 47 36 47 0.75

3 3 1.1e-28 2.7e-24 84.8 0.4 1 51 57 108 57 109 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.041	9.7e+02	-0.2	0.1	29	37	16	24	11	24	0.81
2	3	0.35	8.3e+03	-3.2	0.4	30	37	40	47	36	47	0.75
3	3	1.1e-28	2.7e-24	84.8	0.4	1	51	57	108	57	109	0.97

Coding Sequence: atgcCGAAGTCGAAGGAATATCTGTCTGACACTGATGATAGCAGTGAGGAgGAAGCAAAGCCAAGTAAGAAGAGGCAACAGAAGGAAAAAGATGCAGATGAAGATAAAGCGGCGAAAGACGAAAAGAGACCAGCGAAAAAGGCAAAAACGGATGACGAAGAAACTATTTGGGACTTGGGTAACAATCGTCAAGTGAATGTGAGAAATTTCAAAGGCAAATATTATGTCGACATCCGAGAGATGTATTACGACAAGGATGGCGATTTAAAACCAGGAAAAAAAGGAATATGCTTAACTATGCAACAATGGCGAAAGTTCATGGATGTTGTGGAGGAGGTGGATAAAGTGGCAAAATCAAAGAGTTAG
Protein Sequence: MPKSKEYLSDTDDSSEEEAKPSKKRQQKEKDADEDKAAKDEKRPAKKAKTDDEETIWDLGNNRQVNVRNFKGKYYVDIREMYYDKDGDLKPGKKGICLTMQQWRKFMDVVEEVDKVAKSKS

Sequence clustering based on sequence similarity using MMseqs2