Afon000092.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles fontenillei
Gene Symbol
-
Assembly
GCA_008817895.1
Location
VTWG01002017.1:87355-93895[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0059 0.34 11.2 2.8 2 23 425 446 424 446 0.97
2 25 0.00036 0.02 15.0 2.0 1 23 452 474 452 474 0.99
3 25 0.042 2.4 8.5 2.0 1 23 484 506 484 506 0.97
4 25 2.3 1.3e+02 3.0 0.0 3 23 531 558 529 558 0.78
5 25 0.87 49 4.4 1.3 2 23 565 586 564 586 0.89
6 25 1.4 81 3.7 0.3 1 22 592 610 592 612 0.76
7 25 0.00012 0.007 16.5 0.2 1 20 624 643 624 644 0.97
8 25 0.0081 0.46 10.8 1.0 2 23 653 674 652 674 0.97
9 25 0.00012 0.007 16.5 0.4 2 23 680 701 679 701 0.93
10 25 0.74 42 4.6 2.0 2 23 710 731 709 731 0.95
11 25 0.00021 0.012 15.8 1.8 2 21 738 757 737 758 0.94
12 25 0.0019 0.11 12.8 3.1 1 23 769 791 769 791 0.98
13 25 0.00098 0.055 13.7 2.5 1 23 797 820 797 820 0.98
14 25 6.6 3.7e+02 1.6 1.6 1 22 1199 1222 1199 1224 0.62
15 25 0.013 0.76 10.1 3.3 2 23 1231 1252 1230 1252 0.97
16 25 0.019 1.1 9.6 2.8 2 23 1259 1280 1258 1280 0.98
17 25 0.013 0.76 10.1 0.9 1 23 1290 1312 1290 1312 0.97
18 25 2.4 1.3e+02 3.0 0.0 9 23 1349 1364 1336 1364 0.82
19 25 0.95 54 4.3 0.3 2 23 1371 1392 1370 1392 0.95
20 25 0.00013 0.0071 16.5 0.3 1 20 1430 1449 1430 1450 0.96
21 25 0.0086 0.49 10.7 1.9 2 23 1459 1480 1458 1480 0.97
22 25 0.00047 0.027 14.7 0.7 2 23 1486 1507 1485 1507 0.95
23 25 0.00046 0.026 14.7 2.0 3 21 1545 1563 1543 1564 0.94
24 25 1.3e-05 0.00075 19.5 0.8 1 23 1575 1597 1575 1597 0.99
25 25 0.00098 0.055 13.7 2.5 1 23 1603 1626 1603 1626 0.98

Sequence Information

Coding Sequence
ATGGCCCACATCACCAGCTGTGCGCTTTGTTTAACAGCCGAGTCCCAGTGGTTCGTTCGAGTATTTGACGAAGCTAACACGACGCTCAATATGGCACAGATCATATCGAAATATTTATGGTTTGATcTAAAACCGGCCGCCCAGCCGTGCGTGTGCGGTGAATGCTGGAGCAGTGTGCacgattttcatcaattctACACCAAACTGGAGAACATTCATTGTGACGAGTTAGTTGCAGCGGACAGTACAGAGCAACAACCGCCTGAATTTGAGCTTCCAGAAGAAACCCACCAAAAGGAAGATCAGTTGCAGAAAAGCATCGATGATGGGTATGAAAGGAAGCATGTTCCCACAGTTGAAGTCATTGACAGCAGCGAGAAGAGAAACAACTCAGACAGCGCTGCGAACGAACCGGCGAAACTCCACACGCAAACAGACGCCATGGACACTATGGACAAAGGAGACAAGAAACATTTCGTGGAGGTGGAAGATTACGCTAGCAATGATGATGACACCGGCGGCTATTGCCCATCGGATGACAACATGCTGGATGGTGATACACTTAACACCGAAGGCAGGGATGAATCTATCGATAAAAAGCCTACGATGAATAACGTAACCGTTGTCGCCATACCTGTGGAACAGCTCTCCGTAAAGCGTGGTAGAGGCCGTCCACCAAAGCCAAAGCTGGAACAGCAAAGCGTAGCAGTAGATGCAAAAGAATCTCCAAAGGATACGAGCGTCTCGGAGCAAACACCTGCGAAACGTCCCAGGGGTCGTCCACCAAAGCGCAAGCTGGACATTTCAAGCGCTTCGCCGAACGTTGCTCAGCAAAATGAAGCACCGCCTGCTGTAATTGAAACGTCACTTGTTACCACCACGACCGAACCCGTTAAGCGACGCAGAGGTAGACCACCGAAAAATGCCCTTACCGCCGTTGCGGTACATTCTGGCCGTGGGAGGAAAGTTCACTCTGTTACCGGCAACAAACGGTCAACCGCGCTGCGGACgaaagtgaagaaagaaataatACGTGGACAGGAGCCAACATACACGGACAGCGGTGAGAGCGAATCGGAGAATGGTTCAGAATATGAAGCGACGAgtgctaaaaaaaaaccgccaaaGCGTGAGAAGAGCGACCGGGACGAGCGAATATTTAAGTACGTCGATGAGTTTTGCTGCCATTACTGTGTGGAAAATGTGACGTTCAAGCGGTTCGTCGATGCGGACCGCCACTACAAGCTGGTGCACAACGAGCCGGGCTTTCTGAAGTGTACGAAATGCGAGAAGAAGTGTTTTACGCCCGGCATGTTCGTGAGCCACATGGAGACGCACGAAGATCCGGAAAAGTATAAATGCAACATTTGCGGCAAAATAACGGACTGTAACATCTCGCTCAAGAAGCACATGCGAGTGCATTTGAGTCAGCTGGAAGAGAACCTACCCTTCCCTTGCAGTCGTTGCAAGCGAAAGTTCGAATCGGAGGAGCAGCGCAACAAGCACGAAAAGCTGCACGTGCCCAAACCGCTGGTCAAGCGGGAAAAGGGCCCGGATCTGGAGGTGCTGGCGTTCTACAAACGCATCTACTGCGATGTGTGCGAAGAGCAAACCCCCGATTCGACCTCGTTCGAGAACTTTTGGGACCTGCGGGTGCACATGGAGCAGGAGCACAACAAGGGAGCGTACCTGAAATGCCCGATCTGCAACAAGAGGAATCTGTACCGGCAGCATCTCATCACGCATATCGATATGCACAATAATCCGGAGAAGTATCGGTGTGAGGTTTGCAAGGAAGTCTATCAAAATCTCGATTCGCACATGGTCAAAGCCCACACACCCACGACTGCGATTCCGGCGGACAGAAAGTACAAGTGTGACCAGTGCGGACGAATGTTTAACTTCCTGGCCAATTTGAAAATGCACATTGATTGTGTTCATGGCTCGAAAGACATCCGTTGCAATGTATGCAATAAGTACTTCAATCTCAAAGCGTTCCAGGTGCACAAGCGAACAGCTCACACCGACCAGATGCTGATGTGCGAACATTGTCccaaaatgttcaaaacacGTGGCGCGCTGGAGGTACACAAGGGCATTCACGATGATACGCTGGTGCAGTTTACGACCTGCAAGCTCTGCAACAAGCAGATACGGCTTACCAACGTGAAGAAGCACATGACCTCGCAGCACTCCGACGATGGGCCGGTCAGCTGCGAAATGTGTGGCAAATCGTTCCGCTCCATGTTCCACATGAAGCGACACCAGAAGAACACGTGCGAAGCGACGATCGATTCGCGCAAACACAAGTGCGAAATCTGTGGCAAGGGCTTCTGTTTGAAGCTGACGATGATCGAACACATGACGACACATACGCGCACGAACAAGTAccagtgtgcgttttgttttaaatcgtTCGGCTACATTTCGAATCTGTACAAGCATCGCAAGAAGGCACATCCGCTCGAATGGCAAGAGATACAGGCACGTCCGGAGGAAAATATTGCTTCGGTTATAGTTCTGAATCCCGCCAGCGAGCCTCACATTTGTATGGATTGCTGGACCACCATACACAACTTCCATCGGTACTACACCAAGCTCGAAGCCCTCCACGATTCGGACGATGGAACCACAGTCGATGAGTTGACCGCAAACGATGAGATGGGAGAACTGAAAAACATTGAATTCCTCGAGGAAGATGCCGAGGAACTCCGGATGCAGATGAAACAGATTCCCAATGCTTCGTACGATGGAAGCGATGAGCAGGAAAGCCCCAGCAGGGGCTCGGCACtcgagagaaagaagaagtcAAACGATCAGGAGTTTAGCCTTTTCGAAATCGAGGTCGAGCAGGACGGAGATGGAACGGTTTACCGACTGGATGCATTTGAAAACCACGAACGGACGGACCGGCCCGAATCAGAAACCCGCCAACAGCCTGTTATATTGAACGGCCAAATGAAACCGTCCAGTGCTGGGGAAAGTTCAACCGTCGCTATCGACTTCTTCGTGCCGGAGGACGAACAGCCCGTCAAGCGTGGCCGAGGCCGGCCACGGAAGCAGATCAAAGTGGAACCGGACACATCGTTGCGGatcattaaaaaagaaaacaattccaGCATGGACGAGCACAACACCTCCCTGGATTCGACGGGTGGCAACGATGAGCAAGTGCCTGTTAAGCGTCGCCGAGGTCGTCCACCGAAGAATGCGAGTGTGCAGCGAAACGCCTCACCAATCGTACCCACCCCAAGGGCAATAAAGAGAGAGGTAAAAATGGAGCGGGAAGACGAGGATGCGCCAGACAGTGGTGGTGCCTCACGTCCCGAACGAAGATCGACACGTGTGCGGAAGGCAAAATATTTCAGCGATATGGAGCAGGACagcgatgaggaggaggatgaggaggaagaggtaaaagaggaagaaacagAGCCGAGCGAATATGAACCGGGCGATGATCCGGAGTACGAGGCGAGGCTGCAGCTGCAACGGGAACTGAATATGGATGATTTTGCCTTCTACGAGTATCAGTGCAGTCTGGAAAACGATCACGGTGCGCGCGATAACAAGATCTTTCAGTATGTGGACGAGTTTGCGTGTCACGTCTGTGAGGAGAAAGTTACGTTCAAACGGTTTGCCGAGGCGCACTTGCACTACCGGGTGGAGCACAACCAGCCGCCGTATCTGAAGTGTCCCAGGTGTGAGAAGAAATGCCACACGCCGGGAATGTTCGTGAGTCACATGGAGACGCACGACGATCCGGAGAAGAATAAGTGCCAGATCTGCGGCAAGTACACGGACTGCAACATATCGCTGAAGAAGCACATGCGCGTGCACCAGAGCCAGCTGGAGGAGAACCTCCCGTATCCGTGCAGTTTGTGCAAGCGAAAGTTCGAGACGGAGGATCTGCGGGAGAAGCACGAGAAGCTGCACGTGCCGAAACCGCACGTACCGAAGGAGAAAGGACCCGACCACGAGGTGCTGGACTTTTACAAGGTCATCGCGTGCGATATATGCGAGGAGGAGCAGACCGACTCGCCGACGTACGACAACTTGAGCGACCTGCGCGCCCACATGGTGAAggagcacaacaaaaacatgtacCTGCGGTGTCCCTATTGCTCCACCAGGCAGGTCAACCGGCAACAGGTCATCACGCACATCGACATGCACAACAATCCGGAAAAGTATCGATGCGAAGTCTGCAAGGAGGTGCACCAGAATCTGCATCAACACATGATGAAGGCCCATGCGCCTACTACGGCGGACGAGGCGGACAAAAAGTACAAGTGCGATCAGTGTGGAAGGTCGTTCAACTTCCTGGCGAACTTAAAGATGCACGTGGATTGCGTCCACGGCGTGAAGGATGTGAAGTGCAATGTCTGCAACAAATTCTTCAACTACAGAGCCTATCGGACGCACAAGCGTACCGCGCACACCGACCTGATGCTGATGTGCGAGCTCTGCCCAAAGATGTTCAAAAATCGAAAGTCGTTCGAAGTGCACAAAGCTTCGCACGAGGGCCTGATGCTGCGGATGACGAACTGTGTGCTGTGCGGTAAGCTCATACGCACCTGCAGCATGTCGAAGCACATGAAAACGATCCACTCGGAGGAGGACCCGGTCAATTGTGATCTGTGCGGCAAAATGTTCCGCACCACGTTCCACATGAAGCGCCATCAGAAGAACACGTGCGAGGTGACGATGGATTCGCGCTCCTTCAAGTGCGAGGTGTGCGGCAAGGGTTTCTCCACCAAGCTGACGATGATGGAACATATGACGACGCACACGCGCACCAATCAGTATCAGTGCGCGTTCTGCTTCAAATCGTTCGGCTACATCTCGAACCTGTACAAGCACCGGAAGAAGGCACACCCGCTCGAGTGGCAGGAGGTGCAGGCGCACCCGGAAGAAAACATTGCATCGGTAATCGTCGTTCGAAACTGA
Protein Sequence
MAHITSCALCLTAESQWFVRVFDEANTTLNMAQIISKYLWFDLKPAAQPCVCGECWSSVHDFHQFYTKLENIHCDELVAADSTEQQPPEFELPEETHQKEDQLQKSIDDGYERKHVPTVEVIDSSEKRNNSDSAANEPAKLHTQTDAMDTMDKGDKKHFVEVEDYASNDDDTGGYCPSDDNMLDGDTLNTEGRDESIDKKPTMNNVTVVAIPVEQLSVKRGRGRPPKPKLEQQSVAVDAKESPKDTSVSEQTPAKRPRGRPPKRKLDISSASPNVAQQNEAPPAVIETSLVTTTTEPVKRRRGRPPKNALTAVAVHSGRGRKVHSVTGNKRSTALRTKVKKEIIRGQEPTYTDSGESESENGSEYEATSAKKKPPKREKSDRDERIFKYVDEFCCHYCVENVTFKRFVDADRHYKLVHNEPGFLKCTKCEKKCFTPGMFVSHMETHEDPEKYKCNICGKITDCNISLKKHMRVHLSQLEENLPFPCSRCKRKFESEEQRNKHEKLHVPKPLVKREKGPDLEVLAFYKRIYCDVCEEQTPDSTSFENFWDLRVHMEQEHNKGAYLKCPICNKRNLYRQHLITHIDMHNNPEKYRCEVCKEVYQNLDSHMVKAHTPTTAIPADRKYKCDQCGRMFNFLANLKMHIDCVHGSKDIRCNVCNKYFNLKAFQVHKRTAHTDQMLMCEHCPKMFKTRGALEVHKGIHDDTLVQFTTCKLCNKQIRLTNVKKHMTSQHSDDGPVSCEMCGKSFRSMFHMKRHQKNTCEATIDSRKHKCEICGKGFCLKLTMIEHMTTHTRTNKYQCAFCFKSFGYISNLYKHRKKAHPLEWQEIQARPEENIASVIVLNPASEPHICMDCWTTIHNFHRYYTKLEALHDSDDGTTVDELTANDEMGELKNIEFLEEDAEELRMQMKQIPNASYDGSDEQESPSRGSALERKKKSNDQEFSLFEIEVEQDGDGTVYRLDAFENHERTDRPESETRQQPVILNGQMKPSSAGESSTVAIDFFVPEDEQPVKRGRGRPRKQIKVEPDTSLRIIKKENNSSMDEHNTSLDSTGGNDEQVPVKRRRGRPPKNASVQRNASPIVPTPRAIKREVKMEREDEDAPDSGGASRPERRSTRVRKAKYFSDMEQDSDEEEDEEEEVKEEETEPSEYEPGDDPEYEARLQLQRELNMDDFAFYEYQCSLENDHGARDNKIFQYVDEFACHVCEEKVTFKRFAEAHLHYRVEHNQPPYLKCPRCEKKCHTPGMFVSHMETHDDPEKNKCQICGKYTDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFETEDLREKHEKLHVPKPHVPKEKGPDHEVLDFYKVIACDICEEEQTDSPTYDNLSDLRAHMVKEHNKNMYLRCPYCSTRQVNRQQVITHIDMHNNPEKYRCEVCKEVHQNLHQHMMKAHAPTTADEADKKYKCDQCGRSFNFLANLKMHVDCVHGVKDVKCNVCNKFFNYRAYRTHKRTAHTDLMLMCELCPKMFKNRKSFEVHKASHEGLMLRMTNCVLCGKLIRTCSMSKHMKTIHSEEDPVNCDLCGKMFRTTFHMKRHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMMEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQAHPEENIASVIVVRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00104557; iTF_00107159; iTF_00095805;
90% Identity
iTF_00095805;
80% Identity
-