Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027928.1:41176720-41183609[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0061 0.32 11.2 2.8 2 23 425 446 424 446 0.97

2 24 0.00037 0.019 15.1 2.0 1 23 452 474 452 474 0.99

3 24 0.043 2.2 8.6 2.0 1 23 484 506 484 506 0.97

4 24 2.4 1.3e+02 3.1 0.0 3 23 531 558 529 558 0.78

5 24 0.9 47 4.4 1.3 2 23 565 586 564 586 0.89

6 24 1.5 77 3.7 0.3 1 22 592 610 592 612 0.76

7 24 0.00013 0.0067 16.5 0.2 1 20 624 643 624 644 0.97

8 24 0.0084 0.44 10.8 1.0 2 23 653 674 652 674 0.97

9 24 0.00013 0.0067 16.5 0.4 2 23 680 701 679 701 0.93

10 24 0.76 40 4.6 2.0 2 23 710 731 709 731 0.95

11 24 0.00022 0.011 15.8 1.8 2 21 738 757 737 758 0.94

12 24 0.0019 0.1 12.8 3.1 1 23 769 791 769 791 0.98

13 24 0.001 0.053 13.7 2.5 1 23 797 820 797 820 0.98

14 24 6.8 3.5e+02 1.6 1.6 1 22 1199 1222 1199 1224 0.62

15 24 0.077 4 7.8 4.3 2 23 1234 1255 1231 1255 0.95

16 24 0.014 0.72 10.1 0.9 1 23 1265 1287 1265 1287 0.97

17 24 2.4 1.3e+02 3.0 0.0 9 23 1324 1339 1311 1339 0.82

18 24 0.98 52 4.3 0.3 2 23 1346 1367 1345 1367 0.95

19 24 0.00013 0.0068 16.5 0.3 1 20 1405 1424 1405 1425 0.96

20 24 0.0089 0.47 10.7 1.9 2 23 1434 1455 1433 1455 0.97

21 24 0.00049 0.026 14.7 0.7 2 23 1461 1482 1460 1482 0.95

22 24 0.00047 0.025 14.7 2.0 3 21 1520 1538 1518 1539 0.94

23 24 1.4e-05 0.00072 19.6 0.8 1 23 1550 1572 1550 1572 0.99

24 24 0.001 0.053 13.7 2.5 1 23 1578 1601 1578 1601 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0061	0.32	11.2	2.8	2	23	425	446	424	446	0.97
2	24	0.00037	0.019	15.1	2.0	1	23	452	474	452	474	0.99
3	24	0.043	2.2	8.6	2.0	1	23	484	506	484	506	0.97
4	24	2.4	1.3e+02	3.1	0.0	3	23	531	558	529	558	0.78
5	24	0.9	47	4.4	1.3	2	23	565	586	564	586	0.89
6	24	1.5	77	3.7	0.3	1	22	592	610	592	612	0.76
7	24	0.00013	0.0067	16.5	0.2	1	20	624	643	624	644	0.97
8	24	0.0084	0.44	10.8	1.0	2	23	653	674	652	674	0.97
9	24	0.00013	0.0067	16.5	0.4	2	23	680	701	679	701	0.93
10	24	0.76	40	4.6	2.0	2	23	710	731	709	731	0.95
11	24	0.00022	0.011	15.8	1.8	2	21	738	757	737	758	0.94
12	24	0.0019	0.1	12.8	3.1	1	23	769	791	769	791	0.98
13	24	0.001	0.053	13.7	2.5	1	23	797	820	797	820	0.98
14	24	6.8	3.5e+02	1.6	1.6	1	22	1199	1222	1199	1224	0.62
15	24	0.077	4	7.8	4.3	2	23	1234	1255	1231	1255	0.95
16	24	0.014	0.72	10.1	0.9	1	23	1265	1287	1265	1287	0.97
17	24	2.4	1.3e+02	3.0	0.0	9	23	1324	1339	1311	1339	0.82
18	24	0.98	52	4.3	0.3	2	23	1346	1367	1345	1367	0.95
19	24	0.00013	0.0068	16.5	0.3	1	20	1405	1424	1405	1425	0.96
20	24	0.0089	0.47	10.7	1.9	2	23	1434	1455	1433	1455	0.97
21	24	0.00049	0.026	14.7	0.7	2	23	1461	1482	1460	1482	0.95
22	24	0.00047	0.025	14.7	2.0	3	21	1520	1538	1518	1539	0.94
23	24	1.4e-05	0.00072	19.6	0.8	1	23	1550	1572	1550	1572	0.99
24	24	0.001	0.053	13.7	2.5	1	23	1578	1601	1578	1601	0.98

Sequence Information

Coding Sequence: ATGGCCCACATCACCAGTTGTGCGCTTTGTTTAACAGCCGAGTCCCAGTGGTTCGTTCGAGTATTTGACGAAGCTAACACGACGCTCAATATGGCACAGATCATATCGAAATATTTATGGTTTGATCTAAAACCGGCCGCCCAGCCGTGCGTGTGCGGTGAATGCTGGAGCAGTGTGCACGATTTTCATCAATTCTACACCAAACTGGAGAACATTCATTGTGACGAGTTAGTTGCAGCGGACAGTACAGAGCAACAACCGCCTGAATTTGAGCTGCCAGAAGAAACCCACCAAAAGGAAGATCAGTTGCAGAAAAGCATCGATGATGGGTATGAAAGGAAGCATGTTCCCACAGTTGAAGTCATTGACAGCAGCGAGAAGAGAAACAACTCAGACAGCGCTGCGAACGAACCGGCGAAACCCCACACGCAAACAGACGCCATGGACACTATGGACAAAGGAGACAAGAAACATTTCGTGGAGGTGGAAGACTATGCTAGCAATGATGATGACACCGGCGGCTATTGCCCATCGGATGACAACATGCTGGATGGTGATACACTTAACACCGAAGGCAGGGATGAATCTATCGATAAAAAGCATACGATGAATAACGTAACCGTTGTCGCCATACCTGTGGAACAGCTCTCCGTAAAGCGTGGTAGAGGCCGTCCACCAAAGCCAAAGCTGGAACAGCAAAGCATAGCAGTAGATGCAAAAGAATCTCCAAAGGATACGAGCATCTCGGAACAAACACCTGCGAAACGTCCCAGGGGTCGTCCACCAAAGCGAAAGCTGGACATTTCAAGCGCCTCGCCGAACGTTGCTCAGAAAAGTGAAGCACCGCCTGCTGTAATTGAAACGTCACTTGTTGCCACCACGACCGAACCCGTTAAGCGACGCAGAGGTAGACCTCCGAAAAATGCCCTTACCGCCGTTGCGGTACATTCTGGCCGTGGGAGGAAAGCTCACTCTGTTACTGGCCACAAACGGTCGATCGCGCTGCGGACGAAAGTGAAGAAAGAAATAATACGTGGACAGGAGCCAACATACACGGATAGCGGTGAGAGCGAATCGGAGAATGGTTCGGATTATGAAGCGGCGAGTGCTAAAAAAAAGCCGCCAAAGCGTGAGAAGAGCGACCGGGACGAGCGAATATTTAAGTACGTCGATGAGTTTTGCTGCCATTACTGTGTGGAAAATGTGACGTTCAAGCGGTTCGTCGATGCGGACCGCCACTACAAGCTGGTGCACAACGAGCCGGGCTTTCTGAAGTGTACGAAATGCGAGAAGAAGTGTTTTACGCCCGGCATGTTCGTGAGCCACATGGAGACGCACGAAGATCCGGAAAAGTATAAATGCAACATTTGCGGCAAAATAACGGACTGTAACATCTCGCTCAAGAAGCACATGCGAGTGCATTTGAGTCAGCTGGAAGAGAACCTACCCTTCCCTTGCAGTCGTTGCAAACGAAAGTTTGAATCGGAGGAGCAGCGCAACAAGCACGAAAAGCTGCACGTGCCCAAACCGCTGGTCAAGCGAGAAAAGGGCCCGGATCTGGAGGTGTTGGCGTTCTACAAACGCATCTACTGCGATGTGTGCGAAGAGCAAACCCCCGATTCGACCTCGTTTGAGAACTTCTGGGACCTGCGGGTGCACATGGAGCAGGAGCACAACAAGGGAGCGTACCTGAAATGCCCGATCTGCAACAAGAGGAATCTGTACCGGCAGCATCTCATCACGCATATCGATATGCACAATAATCCGGAGAAGTATCGGTGTGAGGTTTGCAAGGAAGTCTATCAAAATCTCGATTCGCACATGGTCAAAGCCCACACACCCACGACTGCGATTCCGGCGGACAGAAAGTACAAGTGTGACCAGTGCGGACGAATGTTTAACTTCCTGGCCAATTTGAAAATGCACATTGACTGTGTTCATGGCTCAAAAGACATCCGTTGCAATGTATGCAATAAGTACTTCAATCTCAAAGCGTTCCAGGTGCACAAGCGAACAGCTCACACCGACCAGATGCTGATGTGCGAACATTGTCCCAAAATGTTCAAAACACGCGGCGCGCTAGAGGTGCACAAGGGCATTCACGATGATACGCTGGTGCAGTTTACGACCTGCAAGCTCTGCAACAAGCAGATACGGCTTACCAACGTGAAGAAGCACATGACCTCGCAGCACTCCGACGATGGGCCGGTCAGCTGCGAAATGTGTGGCAAATCGTTCCGCTCCATGTTCCACATGAAGCGGCACCAGAAGAACACGTGCGAAGCGACGATCGATTCGCGCAAACACAAGTGCGAAATCTGTGGCAAGGGCTTTTGTTTGAAGCTGACGATGATCGAACACATGACGACACACACGCGCACGAACAAGTACCAGTGTGCGTTTTGTTTTAAATCGTTTGGCTACATTTCGAATCTGTACAAGCATCGCAAGAAGGCACATCCGCTCGAATGGCAAGAGATACAGGCACGTCCGGAGGAAAATATTGCTTCGGTTATAGTTCTGAATCCCGCCAGCGAGCCTCACATTTGTATGGATTGCTGGACCACCATACACAACTTCCATCGGTACTACACCAAGCTCGAAGCCCTCCACGATCGGGACGATGGAATCACAGTCGATGAGTCGACCGCGAACGATGAGATGGGAGAGCTGAAAAACATTGAATTCCTCGAGGAAGATGCCGAGGAGCTCCGGATGCAGATGAAACAGATTCCCAATGCTTCGTACGATGGAAGCGAAGAGCAGGAAAGCCCCAGCAGGGGCTCGGCACTTGAGAGAAAGAAGAAGTCAAACGATCAGGAGTTTAGCCTTTTCGAAATCGAGGTCGAGCAGGACGGAGATGGAACGGTTTACCGACTGGATGCATTTGAAAACCACGAACAGACGGACCGGCCCGAATCAGAAACCCGCAAACAGCCTGTTATATTGAACGGCCAAATGAAACCGTCCAGTGCTGGAGAAAGTTCAACCGTCGCTATCGACTTCTTCGTACCGGAGGACGAACCGCCCGTCAAGCGTGGCCGAGGCCGCCCACGGAAGCAGATCAAAGTAGAACCGGACACATCGTTGCGGATCATTAAAAAAGAAAACAATTCCAGCATGGACGAGCACAACACCTCCCTGGATTCGACGGGTGGCAACGATGAGCAAGTGCCTGTTAAGCGTCGCCGAGGTCGTCCACCGAAGAATGCGAGTGTGCAGCGAAACGCCTCACCAATCGTACCCACCCCAAGGGCAATAAAGAGAGAGGTAAAAACGGAGCGGGAAGACGAGGATGCGCCAGACAGTGGTGGTACCTCACGACCCGAACGGAGATCGACACGTGTGCGGAAGGCAAAATATTTCAGCGATATGGAGCAGGACAGCGATGAGGAGGAGGATGAGGAGGAGGAGGTACAAGAGGAAGAAACAGAGCCGAGCGAATATGAACCGGGCGATGATCCGGAGTACGAGGCGAGGCTGCAGCTGCAACGGGAACTGAATATGGATGATTTTGCCTTCTACGAGTATCAGTGCAGTCTGGAGAACGATCACGGTGCGCGCGATAACAAGATCTTTCAGTATGTGGACGAGTTTGCGTGTCACGTCTGTGAGGAGAAAGTGACGTTCAAACGGTTTGCCGAAGCGCACTTGCACTACCGGGTGGAGCACAACCAGCCGCCGTATCTGAAGTGTCCCAGGTGCCAGATCTGCGGCAAGTACACGGACTGTAACATATCGCTGAAGAAGCACATGCGCGTGCACCAGAGCCAGCTGGAGGAGAACCTCCCGTATCCGTGCAGTTTGTGCAAGCGAAAGTTCGAGACGGAGGATCTGCGGGAGAAGCACGAGAAGCTGCACGTGCCGAAACCGCACGTACCGAAGGAGAAAGGACCCGACCACGAGGTGCTGGACTTTTACAAGGTCATCGCGTGCGATATATGCGAGGAGGAGCAGACCGACTCGCCGACGTACGACAACTTGAGCGACCTGCGCGCCCACATGGTGAAGGAGCACAACAAAAACATGTACCTGCGGTGTCCCTATTGTTCCACCAGGCAAGTCAACCGGCAACAGGTCATCACGCACATCGACATGCACAACAATCCGGAAAAGTATCGATGCGAAGTCTGCAAGGAGGTGCACCAGAATCTGCATCAACACATGATGAAGGCCCATGCGCCAACTACGGCGGACGAGGCGGACAAAAAGTACAAGTGCGATCAGTGTGGAAGGTCGTTCAACTTCCTGGCGAACTTAAAGATGCACGTGGATTGCGTCCACGGCGTGAAGGACGTGAAGTGCAATGTGTGCAACAAATTCTTCAACTACAGAGCCTATCGGACGCACAAGCGTACCGCGCACACCGACCTGATGCTGATGTGCGAGCTCTGTCCAAAGATGTTCAAAAATCGAAAGTCGTTCGAAGTGCACAAAGCTTCGCACGAGGGCCTGATGCTGCGGATGACGAACTGTGTGCTGTGCGGTAAGCTCATACGCACCTGCAGCATGTCGAAGCACATGAAAACGATCCACTCGGAGGAGGACCCGGTCAATTGCGATCTGTGCGGCAAAATGTTCCGCACCACGTTCCACATGAAGCGCCATCAGAAGAACACGTGCGAGGTGACGATGGATTCGCGATCCTTCAAGTGCGAGGTGTGTGGCAAGGGTTTCTCCACCAAGCTGACGATGATGGAACATATGACGACGCACACGCGCACCAATCAGTATCAGTGCGCGTTCTGCTTCAAATCGTTCGGCTACATCTCGAACCTGTACAAGCACCGGAAGAAGGCACACCCGCTCGAGTGGCAGGAGGTGCAGGCGCACCCGGAAGAAAACATTGCATCGGTAATCGTCGTTCGAAACTGA
Protein Sequence: MAHITSCALCLTAESQWFVRVFDEANTTLNMAQIISKYLWFDLKPAAQPCVCGECWSSVHDFHQFYTKLENIHCDELVAADSTEQQPPEFELPEETHQKEDQLQKSIDDGYERKHVPTVEVIDSSEKRNNSDSAANEPAKPHTQTDAMDTMDKGDKKHFVEVEDYASNDDDTGGYCPSDDNMLDGDTLNTEGRDESIDKKHTMNNVTVVAIPVEQLSVKRGRGRPPKPKLEQQSIAVDAKESPKDTSISEQTPAKRPRGRPPKRKLDISSASPNVAQKSEAPPAVIETSLVATTTEPVKRRRGRPPKNALTAVAVHSGRGRKAHSVTGHKRSIALRTKVKKEIIRGQEPTYTDSGESESENGSDYEAASAKKKPPKREKSDRDERIFKYVDEFCCHYCVENVTFKRFVDADRHYKLVHNEPGFLKCTKCEKKCFTPGMFVSHMETHEDPEKYKCNICGKITDCNISLKKHMRVHLSQLEENLPFPCSRCKRKFESEEQRNKHEKLHVPKPLVKREKGPDLEVLAFYKRIYCDVCEEQTPDSTSFENFWDLRVHMEQEHNKGAYLKCPICNKRNLYRQHLITHIDMHNNPEKYRCEVCKEVYQNLDSHMVKAHTPTTAIPADRKYKCDQCGRMFNFLANLKMHIDCVHGSKDIRCNVCNKYFNLKAFQVHKRTAHTDQMLMCEHCPKMFKTRGALEVHKGIHDDTLVQFTTCKLCNKQIRLTNVKKHMTSQHSDDGPVSCEMCGKSFRSMFHMKRHQKNTCEATIDSRKHKCEICGKGFCLKLTMIEHMTTHTRTNKYQCAFCFKSFGYISNLYKHRKKAHPLEWQEIQARPEENIASVIVLNPASEPHICMDCWTTIHNFHRYYTKLEALHDRDDGITVDESTANDEMGELKNIEFLEEDAEELRMQMKQIPNASYDGSEEQESPSRGSALERKKKSNDQEFSLFEIEVEQDGDGTVYRLDAFENHEQTDRPESETRKQPVILNGQMKPSSAGESSTVAIDFFVPEDEPPVKRGRGRPRKQIKVEPDTSLRIIKKENNSSMDEHNTSLDSTGGNDEQVPVKRRRGRPPKNASVQRNASPIVPTPRAIKREVKTEREDEDAPDSGGTSRPERRSTRVRKAKYFSDMEQDSDEEEDEEEEVQEEETEPSEYEPGDDPEYEARLQLQRELNMDDFAFYEYQCSLENDHGARDNKIFQYVDEFACHVCEEKVTFKRFAEAHLHYRVEHNQPPYLKCPRCQICGKYTDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFETEDLREKHEKLHVPKPHVPKEKGPDHEVLDFYKVIACDICEEEQTDSPTYDNLSDLRAHMVKEHNKNMYLRCPYCSTRQVNRQQVITHIDMHNNPEKYRCEVCKEVHQNLHQHMMKAHAPTTADEADKKYKCDQCGRSFNFLANLKMHVDCVHGVKDVKCNVCNKFFNYRAYRTHKRTAHTDLMLMCELCPKMFKNRKSFEVHKASHEGLMLRMTNCVLCGKLIRTCSMSKHMKTIHSEEDPVNCDLCGKMFRTTFHMKRHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMMEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQAHPEENIASVIVVRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101121;
90% Identity: iTF_00101121; iTF_00104557; iTF_00107159;
80% Identity: -