Amel005367.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles melas
Gene Symbol
-
Assembly
GCA_000473525.2
Location
AXCO02002227.1:16595-23095[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0066 0.36 11.2 2.8 2 23 421 442 420 442 0.97
2 25 0.0004 0.021 15.1 2.0 1 23 448 470 448 470 0.99
3 25 0.046 2.5 8.5 2.0 1 23 480 502 480 502 0.97
4 25 2.6 1.4e+02 3.0 0.1 3 23 527 554 525 554 0.77
5 25 0.98 53 4.4 1.3 2 23 561 582 560 582 0.89
6 25 0.9 49 4.5 0.3 1 23 588 608 588 608 0.85
7 25 0.00014 0.0074 16.5 0.2 1 20 620 639 620 640 0.97
8 25 0.0091 0.49 10.8 1.0 2 23 649 670 648 670 0.97
9 25 0.00014 0.0075 16.5 0.4 2 23 676 697 675 697 0.93
10 25 0.83 45 4.6 2.0 2 23 706 727 705 727 0.95
11 25 0.00023 0.013 15.8 1.8 2 21 734 753 733 754 0.94
12 25 0.0021 0.11 12.8 3.1 1 23 765 787 765 787 0.98
13 25 0.0011 0.059 13.7 2.5 1 23 793 816 793 816 0.98
14 25 4.1 2.2e+02 2.4 1.5 1 21 1193 1215 1193 1218 0.62
15 25 0.015 0.8 10.1 3.3 2 23 1225 1246 1224 1246 0.97
16 25 0.021 1.1 9.6 2.8 2 23 1253 1274 1252 1274 0.98
17 25 0.015 0.81 10.1 0.9 1 23 1284 1306 1284 1306 0.97
18 25 2.6 1.4e+02 3.0 0.0 9 23 1343 1358 1330 1358 0.82
19 25 1.1 57 4.3 0.3 2 23 1365 1386 1364 1386 0.95
20 25 0.00014 0.0076 16.5 0.3 1 20 1424 1443 1424 1444 0.96
21 25 0.0097 0.52 10.7 1.9 2 23 1453 1474 1452 1474 0.97
22 25 0.00053 0.029 14.7 0.7 2 23 1480 1501 1479 1501 0.95
23 25 0.00051 0.028 14.7 2.0 3 21 1539 1557 1537 1558 0.94
24 25 1.5e-05 0.0008 19.5 0.8 1 23 1569 1591 1569 1591 0.99
25 25 0.0011 0.059 13.7 2.5 1 23 1597 1620 1597 1620 0.98

Sequence Information

Coding Sequence
ATGGCCCACATCACCAGTTGTGCGCTTTGTTTAACAACCGAGTCGCAGTGGTTCGTTCGAGTATTTGACGAAGCTAACACGACGCTCAATATGGCACAGATCATATCCAAATATTTATGGTTTGATCTAAAACCGGACGCCCAGCCGTGTGTGTGCGGTGAATGCTGGAGCAGTGTACACGATTTTCATCAATTCTACACCAAACTGGAGAACATTCATTGTGACGAGTTAGTTGCAGCGGACAGTACAGAGCAACAACCGCCTGAATTTGAGCTGCCAGAAGAAACCCACCAGAAGGAAGATCAGTTGCAGAAAAACATCGATGATGGGTATGAAAGGAAGCATGTTCCCACAGTTGAAGTCATTGACAGCAACGAGAAGAGAAACAACTCAGATAGTGCTGCCATCGAACCGGCGAAACCTCACACGCAATCAGACGCCATCGACATTATGGACAAAGGAGACAAGAAACATTTCGTGGAGGTGGAAGATTATGCTAGCAATGATGATGACACCGGCGGCTATTGCCCATCGGATGATAACATGCTGGATGGTGATACACTTAACACCGAAGGCAGGGATGAATCTATCGATAAAAAACCTACGATAAATAACGTAACCGTTGTCGCCATACCTGTGGAACAGCTCTCCGTAAAGCGTGGTAGAGGCCGTCCACCAAAACCAAAGCTGGAACAGCAAAGCGTAGCAGTAGATGCAAAAGAATCTCCAAAGGATACGAGCGCCTCGGAGGAAACACCTGCGAAACGTCCCAGGGGTCGTCCACCAAAGCGAAAGCTGGACATTTCTGGACCCCTGGACAAAAATGAAGCATCGCCTGCTGTACTTGAAACGTCACTTGTTGCCATCACTACCGAACCCGTTAAGCGACGCAGAGGTAGACCACCGAAAAATGCCCTTACCGCCGTTGCAGTACATTCTGTCCGTGGGAGGAAAGTTCACTCTGTTACCGGCAACAAACGGTCTATCGCGCTGCGGACGAAAGTGAAGAAAGAAATAATACGTGGACAGGAGCCAACATGCACGGATAGCAGTGAGTGCGAATCGGAGAATGGTTCAGATTATGAAGCGGCGAGTGCTAAAAAAAAGCCGCCAAAGCGTGAGAAGAGCGACCGGGACGAGCGAATATTTAAGTACGTCGATGAGTTTTGCTGCCATTACTGTGTGGAAAATGTGACGTTCAAGCGGTTCGTCGATGCGGACCGCCACTACAAGCTGGTGCACAACGAGCCGGGCTTTCTGAAGTGTACGAAATGCGAGAAGAAGTGTTTTACGCCAGGCATGTTCGTGAGCCACATGGAGACGCACGAAGATCCGGAAAAGTATAAATGCAACATTTGCGGCAAAATAACGGACTGTAACATCTCGCTCAAGAAGCACATGCGAGTGCATTTGAGTCAGCTGGAAGAGAACCTACCCTTCCCTTGCAGTCGTTGCAAGCGAAAGTTTGAATCGGAGGAGCAGCGCAACAAGCACGAAAAGCTGCACGTGCCCAAACCGCTGGTCAAGCGGGAAAAGGGCCCGGATCTGGAGGTGCTTGCGTTCTACAAACGCATTTACTGCGATGTGTGCGAAGAGCAAACCCCCAATTCGACCTCGTTCGAGAACTTCTGGGACCTGCGGGTGCACATGGAGCAGGAGCACAACAAGGGAGCGTACCTGAAATGTCCGATCTGCAACAAGAGGAATCTGTACCGGCAGCATCTCATCACGCATATCGATATGCACAATAATCCGGAGAAGTATCGGTGCGAGGTTTGCAAGGAAGTCTATCAGAATCTGGATTCGCACATGATCAAAGCCCACACACCCACGACTGCGATTCCGGCGGATAGAAAGTACAAGTGTGACCAGTGCGGACGGATGTTTAACTTCCTGGCCAATTTGAAAATGCATATTGACTGTGTTCATGGCTCGAAAGACATCCGTTGCAATGTATGCAATAAGTACTTCAATCTCAAAGCGTTCCAGGTGCACAAGCGAACAGCACACACCGACCAGATGCTGATGTGCGAACATTGTCCCAAAATGTTCAAAACACGCGGCGCGCTAGAGGTGCACAAGGGCATTCACGATGATACGCTGGTGCAGTTTACGACCTGCAAGCTCTGCAACAAGCAAATACGGCTTACGAACGTTAAGAAGCACATGACCTCGCAGCACTCCGACGATGGGCCGGTCAGCTGCGAAATGTGTGGCAAATCGTTCCGCTCCATGTTCCACATGAAGCGGCACCAGAAGAACACGTGCGAGGCGACGATCGATTCGCGCAAACACAAGTGCGAAATCTGTGGCAAGGGCTTCTGTTTGAAGCTGACGATGATCGAGCACATGACGACACACACGCGCACGAACAAGTACCAGTGTGCGTTTTGTTTTAAATCGTTCGGCTACATTTCGAATCTGTACAAGCATCGCAAGAAGGCACATCCGCTGGAATGGCAAGAGATACAGGCACGTCCGGAGGAAAATATTGCTTCGGTTATAGTTCTGAATCCCGCCAGCGAGCCTCACATTTGTATGGATTGCTGGACCACCATACACAACTTCCATCGGTACTACACCAAGCTCGAAGCCCTCCACGATCCGGACGATGGAACCACAGTCGATGAGTCGACCCCGAACGATGAGATGGGAGAGCTGAAAAATATTGAATTCCTCGAGGAAGATGCCGAGGAACTGCTGATGCAGATGAAACAGATTCCCAATGCTTCGTACGATGGAAGCGATGAGCAGGAAAGCCCCAGCAGGGGCTCGGCACTTGAGAGCAAGAAGAAGTCAAACGATCAGGAGTTTAGCCTTTTCGAAATCGAGGTCGAGCAGGATGGAGATGGAACGGTGTACCGGCTGGATGCATTTGAAAACCACGAACAGACGGACCAACCCAAACCAGAAACCCGCAAACAACCTGTTATATTGAACGGCCAAATGAAACCGTCCAGTGCTGGAGAAAGTTCAACCGTCGCTATCGACTTCTTCGTACCGGAGGACGAACCGCCTGTCAAGCGTGGCCGAGGCCGCCCACGGAAGCAGATCAAAGAGGAACCGGACACATCATTGCGGATTATTAAAAAAGAAAACAATTCCAGCATGGACGAGCACAACACCTCCCTGGATTCGACGGGTGGCAACGATGAGCAAGTGCCTGTTAAGCGTCGCAGAGGTCGCCCACCGAAGAATGCGAGTGTGCAGCGAAACGCCTCACCAATCGTACCCAACCCAAGGGCATTAAAGAGGGAGGTAAAAACGGAGCGAGAAGACGAGGATGCGCCAGACAGTGGTGGTGCCTCACGACCCGAACGAAGATCGACACGTGTGCGGAAGGCAAAATATTTCAGCGATATGGAGCAGGACAGCGATGAGGAGGAGGAAGTAGAGGTAAAAGAGGAAGAAACAGAGCCGAGCGAATATGAACCGGGCGATGATCCGGAGTACGAGGCGAGGCTGCAGCTTCAACGGGAACTAAATATGGATGATTTTGCCTTCTACGAGTATCAGTGCAGTCTGGAGAACGATCACGGTGCGCGCGATAACAAGATCTTTCAGTATGTGGACGAGTTTGCGTGTCACATCTGTGAGGAGAAAGTTACGTTCAAACGGTTTGCCGAGGCGCACTTGCACTACCGGGTGGAGCACAACCAGCCGCCGTATTTGAAGTGTCCCAGGTGTGAGAAGAAATGCCACACACCGGGAATGTTCGTGAGTCACATGGAGACGCACGACGATCCGGAGAAGAATAAGTGCCAGATCTGCGGCAAGTACACGGACTGCAACATATCGCTGAAAAAGCACATGCGCGTGCACCAGAGCCAGCTGGAGGAGAACCTCCCGTATCCGTGCAGTTTGTGCAAGCGAAAGTTCGAGACGGAGGATCTGCGGGAGAAGCACGAGAAGCTGCACGTGCCGAAACCGTACGTACCGAAGGAGAAAGGACCCGACCAGGAGGTGCTGGACTTTTACAAGGTCATCGCGTGCGATATATGCGAGGAGGAGCAGACCGACTCGCCGACGTACGACAACTTGAGCGACCTGCGCGCCCACATGGTGAAGGAGCACAACAAAAACATGTACCTGCGGTGTCCCTATTGTTCCACCAGGCAGGTCAACCGGCAACAGGTCATCACGCACATCGACATGCACAACAATCCGGAAAAATATCGATGCGAGGTCTGCAAGGAGGTGCACCAGAATCTGCATCAACACATGATGAAGGCCCATGCGCCAACTACGGCGAACGAGGCGGACAAAAAGTACAAGTGCGATCAGTGTGGAAGATCGTTCAACTTCCTGGCGAACTTAAAGATGCACGTGGATTGCGTCCACGGCGTGAAGGATGTGAAGTGCAATGTGTGCAACAAATTCTTCAACTACAGAGCCTATCGGACGCACAAGCGTACCGCGCACACCGACCTGATGCTGATGTGCGAGCTCTGCCCAAAGATGTTCAAAAATCGAAAGTCGTTCGAAGTGCACAAAGCTTCGCACGAGGGCCTGATGCTGCGGATGACGAACTGTGTGCTGTGCGGTAAGCTCATACGCACCTGCAGCATGTCGAAGCACATGAAAACGATCCACTCGGAGGAGGATCCGGTCAATTGCGATCTGTGCGGCAAAATGTTCCGCACCACGTTCCACATGAAGCGCCATCAGAAGAACACGTGCGAGGTGACGATGGATTCGCGCTCCTTCAAGTGCGAGGTGTGCGGCAAGGGTTTCTCCACCAAGCTGACGATGATGGAACATATGACGACGCACACGCGCACCAATCAGTATCAGTGCGCGTTCTGCTTCAAATCGTTCGGCTACATCTCGAACCTGTACAAGCACCGGAAGAAGGCACACCCGCTCGAGTGGCAGGAGGTGCAGGCGCACCCGGAAGAAAACATTGCATCGGTAATCGTCGTTAGAAACTGA
Protein Sequence
MAHITSCALCLTTESQWFVRVFDEANTTLNMAQIISKYLWFDLKPDAQPCVCGECWSSVHDFHQFYTKLENIHCDELVAADSTEQQPPEFELPEETHQKEDQLQKNIDDGYERKHVPTVEVIDSNEKRNNSDSAAIEPAKPHTQSDAIDIMDKGDKKHFVEVEDYASNDDDTGGYCPSDDNMLDGDTLNTEGRDESIDKKPTINNVTVVAIPVEQLSVKRGRGRPPKPKLEQQSVAVDAKESPKDTSASEETPAKRPRGRPPKRKLDISGPLDKNEASPAVLETSLVAITTEPVKRRRGRPPKNALTAVAVHSVRGRKVHSVTGNKRSIALRTKVKKEIIRGQEPTCTDSSECESENGSDYEAASAKKKPPKREKSDRDERIFKYVDEFCCHYCVENVTFKRFVDADRHYKLVHNEPGFLKCTKCEKKCFTPGMFVSHMETHEDPEKYKCNICGKITDCNISLKKHMRVHLSQLEENLPFPCSRCKRKFESEEQRNKHEKLHVPKPLVKREKGPDLEVLAFYKRIYCDVCEEQTPNSTSFENFWDLRVHMEQEHNKGAYLKCPICNKRNLYRQHLITHIDMHNNPEKYRCEVCKEVYQNLDSHMIKAHTPTTAIPADRKYKCDQCGRMFNFLANLKMHIDCVHGSKDIRCNVCNKYFNLKAFQVHKRTAHTDQMLMCEHCPKMFKTRGALEVHKGIHDDTLVQFTTCKLCNKQIRLTNVKKHMTSQHSDDGPVSCEMCGKSFRSMFHMKRHQKNTCEATIDSRKHKCEICGKGFCLKLTMIEHMTTHTRTNKYQCAFCFKSFGYISNLYKHRKKAHPLEWQEIQARPEENIASVIVLNPASEPHICMDCWTTIHNFHRYYTKLEALHDPDDGTTVDESTPNDEMGELKNIEFLEEDAEELLMQMKQIPNASYDGSDEQESPSRGSALESKKKSNDQEFSLFEIEVEQDGDGTVYRLDAFENHEQTDQPKPETRKQPVILNGQMKPSSAGESSTVAIDFFVPEDEPPVKRGRGRPRKQIKEEPDTSLRIIKKENNSSMDEHNTSLDSTGGNDEQVPVKRRRGRPPKNASVQRNASPIVPNPRALKREVKTEREDEDAPDSGGASRPERRSTRVRKAKYFSDMEQDSDEEEEVEVKEEETEPSEYEPGDDPEYEARLQLQRELNMDDFAFYEYQCSLENDHGARDNKIFQYVDEFACHICEEKVTFKRFAEAHLHYRVEHNQPPYLKCPRCEKKCHTPGMFVSHMETHDDPEKNKCQICGKYTDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFETEDLREKHEKLHVPKPYVPKEKGPDQEVLDFYKVIACDICEEEQTDSPTYDNLSDLRAHMVKEHNKNMYLRCPYCSTRQVNRQQVITHIDMHNNPEKYRCEVCKEVHQNLHQHMMKAHAPTTANEADKKYKCDQCGRSFNFLANLKMHVDCVHGVKDVKCNVCNKFFNYRAYRTHKRTAHTDLMLMCELCPKMFKNRKSFEVHKASHEGLMLRMTNCVLCGKLIRTCSMSKHMKTIHSEEDPVNCDLCGKMFRTTFHMKRHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMMEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQAHPEENIASVIVVRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101121;
90% Identity
iTF_00095805;
80% Identity
-