Basic Information

Insect: Anopheles albimanus
Gene Symbol: egg
Assembly: GCA_013758885.1
Location: NC:71122622-71127364[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.5e-15 1.7e-11 42.9 0.1 9 74 792 852 785 854 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.5e-15	1.7e-11	42.9	0.1	9	74	792	852	785	854	0.87

Sequence Information

Coding Sequence: ATGGATGCTCAAGCCTCTAAGAAGGCTGAAgctgaaacggaaacgataTTGTTAGAATCAGACGATGAAACCGAAACTGCCGCCCCTCAAACCTTGGATAGTACCGAAGCTCCTTCAAAAGCTACCGCGAACGAACCGGCTAAATCAGACATTGAAGCACCAGAAATCACTCGGGAGGAACCACCTGAAGATCCGGAGGGGATGGAGCAAATTACAGAAACACCTGCAgcagaaaaggaggaagacgTGATCCTGATTGTGGATGACGAAAAAGAACCCGAAAACGTCGACCAAGCTGTTGAACCCACATCGCAGGAACCTTCCACATTGGAGGCAGATTCCACTGTTGCCGATGGACTAGCGTCGCAAATAGGAAAACTCTGTACTACTGGGGACAGCCAGGACGTGGTGAATGGAACAATCGACGAGGTAATGAATGAAGACGGTCAGGAACAGGAGAACGCTGAAGCACCCAGTGAAGCAGAACCCCAGCAGAACGATATGGAAAATGAGGAGCAAACGACGCAGACGGAAAGTGGAGATGCTTTTGAGATGCTGGTAgaggaaacgatcgaaaaTATTGCCGCAGCCGTTGACGGTAACATTGAGTTGGAAGCTGAACCCGTTGAAGATATCAACGAAAAGGTGAACGCAGAGCCTGTGAAGGACGAGCAGACGAAAACCGATCCTGGCCTTCCTCGGTCCGACTGTTGCAATCTGGAATGTAGTTCGACATCCCGGGAGTACGTTGAGGCACCTTTGTTCGCGATTAACTTTTACGACGTTtcgaagaaaaagaacaaaGCCCCGCTATTGTGCACCGATTGCTTCGGAGCAGTTATCAGAGAGTACGAGAATTATTGCACGATGATAGTAAACCAAACGCCGGTGGTTCGGAATAATCCGACAAAGAAGGAGGTGGTAGAAATTATAGATAGCGATGACGAGGACAAAGATAAGATGGGCCTGCTAAAACATGACAATGAGACACCATTGCCTCAGGATATAATAGCGCTCGTTGAATCGGAGCTGGAGGACGTCATTAAAGAAACATTTGATAAATACAAGATACAGGAACAGATGACGCAGTCCTTCGATTACATTAAGCAGATGATTGCCAAGAATGAAGAATGCTCCAAATATCTCGAACCTACGTTTAAGCAGATGTCGAAGAGGTCGGACGAACAGCTATTTGCCATTTACGGGGCcagaaaattggaaataaaaCAGCTTCCCGAACTAATCATCAACGACCACAACAGTGACATGCATCGCCGGGAGCCAATAACCCAGAGCCAGGTGTACTATGCCTATGGGGACAAACTGTTTGCCAAGTGGAGAGAGTGTCGAGTGATAGATAAAGTGAAGCGAAATAACGAAATCATGTACTATATCAAGTTTCTGCAGCCGGAAGGAAGTCCGTTGCAGTTACGGTCAGCCAAAGGTATTGCTTACCGAACGGCGCCGATAGGAAAGCTGATGCTCGGGACGCGTGTGATTGCGAAGATTGATTCGTACGTTGGCAAAGGTGGAAGTGTGCAAGACGAGTTCTACCCGGGTGTTGTTGCTGAATCGCTGGGAAGCTACAACCGCTTCCGGTATCTGATTTTCTATGACGATGGTTACGCCCAGTACGTGCCACCGAAAGACGTTCGTGTCGTGTGTTTCCAATCGAGGAACGTTTGGGAGGATGTGGATATTCATTCGCGCGAGTTTATCAAGGACTACTTGATCAAAATTTACAAAATCAGGCCGATGGTGCATGTGAAACCCCAGCAACGGCTTATGACCGAGCGAAACGCCACCTGGTACGATACGGTCGTCACGCGGCTCGATGCCAGCCTGATCGAGGTTTATTTCTTCGCGTTAAAGCGCCACGAATGGATTTACCGTGGCTCCACCCGATTTGCACCGTTGTTCTACGGCAAGGGCAAGAATCAGCAACAGTTTGGCAATAAGAAGTACTCCAAACTTCAACAACGCAACGAACCGTCGATCGAGTACATGAcaatcgatgacgacgacgagaacagCGCCGATGGAAAAGAGGGTATCACGAAAAGTCGCTACGATATTATGGGACAGACGGCGGAGCCATCGCCTCCGTCGCAAGGCAGCAAAGCGCCACAAGAAGCCCGCAGCGACGCTGGAAGCAAAGCGAAGCAGGCGCAAACGGCTCGCAAGAGTACGGTCGATCGGCCAACGTATCTCAATCAAAACATCATCTATTGCGATAACGATCGGCCGGAGGGATCTACGACGAACTACACGACGAAGCGCTATCCACCGCCGCAAAAGTTCAAACCGCACAACTGCGGGCCGGACTGTCTGTACAAATCGTCGTTCGATATGCGCTCGTTCAGCCATCTCGGCAAACCATTGCTGTGTGGCTGGGAGCGACAGATATGCAAATCTCGCTTCAAGAAGGTGCCCAGTGTGGTGTACCGGGGTCCGTGTGGTCGCCGTTTGCGGTCGATGGCGGAAGTGCATCGTTACCTGCGCATCACGAAGGCCACGCTGAACGTTGATAACTTCGAGTTCGATCCACagctgcgtgtgtttgcggaGTACCGGCCGCAAAACCTCGTTGTCGACATACCGGACGTTTCGAATGGGCTCGAGTACACGCCCGTTTCGTGTGTGAACTACTTTGACGATACGAAGCCGCCGCCATGCGAGTACTCAACCAAGCGCATACCGACCGAGGGCGTGGATCTGAATTTGGATGAAGATTTTCTGGTCTGCTGTGACTGCGAAGATGATTGCTTCGATAAGAGCAAGTGCCAGTGCTGGCAGTTGACGATCGAGGGCGCGAAATTTCTGGCACCTGACCaaccgatcgaatcgatcggctACGTGTACAAGCGGCTAGATGAATCGGTCATGACCGGTATCTACGAGTGTAATGCGCGGTGTAAGTGCAAAATGAATTGCCTCAACCGTGTCGTCCAGCATCCGCTGCTCACCAAGCTGCAAATTTTCAAAACGAGCAACCGGGGCTGGGGTATCCGTTGCCTCAATGATATAGCCAAAGGCAGCTTCATCTGTGTGTACTCCGGGCACCTGATCACGGACGAGGCGAGCAATCAGATCTGCGCCCAGAACGAGGACCAAACGGGTGACGAGTATTACGCCGAGCTGGACTACATCGAAACGGTGCAGAACACAAAGGAAGGCTACGAGAGCGATGTATCGAAtatcgaggaggaggaagatccGTTGCAGGATCCGACCATCCTGAACGAGGAGTCCGACTCGGGGCCCGAGTATGGGGCTAGCAATATGGATGCCGATTCGGATGAGGAATTCACCTACAAAAGCAAACCATCGCGAATGGCTATTAAGACACGGTCTCAGATTCGAAAGCTGGTAACGGAATCCCAGGACGACGAGCTGACGGATgagaaacaaaaggaaaagaattcTGAAGAGCGCGAACCTATCAATCTCGCACCCAACAAGGACATGTCGCATGCCGAGGCGCTGGGCAAAACTAAGAAAAGAAAGTCTCTTCGCGAATACTACGGAGAGAACGAAGCCACCTACATTATGGACGCCAAAAAGTCTGGCAATCTGGGCCGCTATTTTAATCACTCCTGTGTACCTAATCTGTTCGTACAGAACGTTTTCGTCGACACGCACGATGCCCGGTTTCCGTGGGTGGCCTTCTTTGCGCAGAAATTGATAAAGGCCGGCTCGGAGTTAACGTGGAACTACAACTACGATGTCGGCTCGGTGGCCGGCAAGGTACTCTACTGTCACTGCGGGGAAAAGGAATGCCGTAAACGTTTGCTTTAA
Protein Sequence: MDAQASKKAEAETETILLESDDETETAAPQTLDSTEAPSKATANEPAKSDIEAPEITREEPPEDPEGMEQITETPAAEKEEDVILIVDDEKEPENVDQAVEPTSQEPSTLEADSTVADGLASQIGKLCTTGDSQDVVNGTIDEVMNEDGQEQENAEAPSEAEPQQNDMENEEQTTQTESGDAFEMLVEETIENIAAAVDGNIELEAEPVEDINEKVNAEPVKDEQTKTDPGLPRSDCCNLECSSTSREYVEAPLFAINFYDVSKKKNKAPLLCTDCFGAVIREYENYCTMIVNQTPVVRNNPTKKEVVEIIDSDDEDKDKMGLLKHDNETPLPQDIIALVESELEDVIKETFDKYKIQEQMTQSFDYIKQMIAKNEECSKYLEPTFKQMSKRSDEQLFAIYGARKLEIKQLPELIINDHNSDMHRREPITQSQVYYAYGDKLFAKWRECRVIDKVKRNNEIMYYIKFLQPEGSPLQLRSAKGIAYRTAPIGKLMLGTRVIAKIDSYVGKGGSVQDEFYPGVVAESLGSYNRFRYLIFYDDGYAQYVPPKDVRVVCFQSRNVWEDVDIHSREFIKDYLIKIYKIRPMVHVKPQQRLMTERNATWYDTVVTRLDASLIEVYFFALKRHEWIYRGSTRFAPLFYGKGKNQQQFGNKKYSKLQQRNEPSIEYMTIDDDDENSADGKEGITKSRYDIMGQTAEPSPPSQGSKAPQEARSDAGSKAKQAQTARKSTVDRPTYLNQNIIYCDNDRPEGSTTNYTTKRYPPPQKFKPHNCGPDCLYKSSFDMRSFSHLGKPLLCGWERQICKSRFKKVPSVVYRGPCGRRLRSMAEVHRYLRITKATLNVDNFEFDPQLRVFAEYRPQNLVVDIPDVSNGLEYTPVSCVNYFDDTKPPPCEYSTKRIPTEGVDLNLDEDFLVCCDCEDDCFDKSKCQCWQLTIEGAKFLAPDQPIESIGYVYKRLDESVMTGIYECNARCKCKMNCLNRVVQHPLLTKLQIFKTSNRGWGIRCLNDIAKGSFICVYSGHLITDEASNQICAQNEDQTGDEYYAELDYIETVQNTKEGYESDVSNIEEEEDPLQDPTILNEESDSGPEYGASNMDADSDEEFTYKSKPSRMAIKTRSQIRKLVTESQDDELTDEKQKEKNSEEREPINLAPNKDMSHAEALGKTKKRKSLREYYGENEATYIMDAKKSGNLGRYFNHSCVPNLFVQNVFVDTHDARFPWVAFFAQKLIKAGSELTWNYNYDVGSVAGKVLYCHCGEKECRKRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092819; iTF_00098401;
90% Identity: -
80% Identity: -