Aaqu001319.1
Basic Information
- Insect
- Anopheles aquasalis
- Gene Symbol
- egg
- Assembly
- GCA_002846955.1
- Location
- NJHH01001250.1:10324-15233[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.49 1.2e+03 -1.3 0.0 44 65 307 328 296 339 0.81 2 2 4.3e-15 1.1e-11 43.7 0.1 9 74 800 860 793 862 0.88
Sequence Information
- Coding Sequence
- ATGGATTCTGAAGCCGCCAAGAAGGCTGAAggtgaaacggaaacaatttTGTTAGAATCAGACGATGAAACCGAAACTGCCGCTCTTCCAACCTCGATGGAGAAGTCCGAAGCTGCACCAGCCACCGCGGACGAACCCGCTAAATCCAACATAGAAACGCCAGAAGCCGCTCTACGGAAACCACCAGAAACTCCTAAAGAGCTGGAGAAAGTTGCAGAAACACCTGCAGCAGAACAACACGAGGAAGATGTGATCCTGATTGTGGATGACGATAAAGAACCCGATAATCCCGTCCAAGCGGATGAACCTATATCGGAGCAACCTTCTACTGCAGTAGAGCCACAGCCGGCCAACTGTATCGCAGAAGATTCCACGGTTACCGATGCTCTAGCGTctcaaattggaaaactttgcacTACAGAGAACGGCCAGGACATTGTGAATGAAAGTGCCGACGAGAAAATGAAGGAAGACGCCCAGGAACAAGAGAACGCTGAAGCTCCCAGTGAAgcagaacagcagcataacgatGAGGAGCAGGCGAAGCTGCAGGAAGGTGAGGATGCTTTTGAGATGCTGGTGGAGGCAGCGATCGAAAATATTGCCGCAGCAGTCGACGGTAACTTTGAGCTGGAACCCGGTGAAGATGTGGACGTAAAGGTTGACGCGGATGCGGTTAAGGTTGAGCAGGTGAAACCCGAACCTGCCCTTCCCCGTTCCGATTGTTGCAATCTGGAGTGTAGTTCGACGTGCCGGGAGTACGTTGAAGCACCTCTGTTCGCGATAAACTTTTACGATgtttcgaagaaaaagaaaaaagttcCGCTTTTGTGCACCGACTGCTTTGGGGCAGTTATCAGCGAGTACGAGAATTATTGCTCGATGATAGTGAACCAAACTCCGGTGGtccggaacgatcgaacgaagaaGGAAGTAGTAGAAATTATCGAtagtgatgatgacgaggacaAAGAAAAGATTGACCTgcaaaaatgtcaaaatgAAACACCACTGCATCAGGACATAATAGCGCTCGTTGAATCGGAGCTGGAGGACGTCATTAAAGAAACATTTGATAAATACAAGATACACGAACAGGTGGAGGAGTCTTTCGACTACATTAAAAAGATAATTGCGAAAAATGAAGAATGCTCCAAATACCTTGAACCTGCGATGAAGCAGATGTCGAAGAAAGCGGACGAACATCTATTTGCCATTTACGCGGCcagaaagatagaaagaaaacatCTTCCCGAACTGATCATTGACGACGACCTCAACAGCGACATCCATCGCCGGGAACCTATAACCCAGAGCCACGTGTACTATGCCTCTGGGGACAAACTGTTTGCCAAGTGGAATGAGTGTCGAATTATAGATAAAGTGAAGCGAAATAACGAACTCATGTACTATATCAAATTTCTACAGCCGGAAGGAAGTCCTTTGCAGTTACGGTCATCCAAATGTATTGCCTACCGAACGGCACCGATAGGAAAGCTGATGCTCGGGACGCGCGTGATTGCCAAGATTGATTCGTACGTTGGCAAGGGTGGAAGTGTGCAGGACGCGTTCTACCCGGGCGTGGTTGCTGAATCGCTGGGCAGCTACAACCGCCACCGGTATCTGGTGTTCTATGACGATGGCTACGCCCAGTACCTGCCACCGAAAGACGTTCGGGTCGTGTGTTCCCAATCGAAAAACGTTTGGGAGGACGTGGATATTCATTCGCGCGAGTTTATCAAGGACTATCTAATCAAAATTCACAAAATCAGGCCGATGGTGCATGTGAAACCCCAGCAACGGCTTATGACAGAGCGAAACGCCACCTGGTACGATACAGTCGTAACGCGGCTCGATGCCAGCCTGATCGAGGTTTATTTCGTCGCGTTAAAACGTCATGAATGGATTTACCGTGGCTCCACTCGGTTTGCACCACTGTTCTACGGCATGGGTCAGCATCAGTTTGGCAATAAAAAGTACTCCAAACTTCAACAACGCAACGAACCGTCGATCGAGTACATGaccatcgatgacgatgacgatgacgatgagaagTGCAGCGACGGAAAAGACGGGACTGCGAAAAGCAGCTGCGATATTACGGGCCAGAGGGCAGAGCCATCACCTACCTCGCAAGACAACCACCGGTCAAAAGAAGCCCGCAGCGACAATGGAGGCAAAGCGAAACCGACGCAAACGGCACGGAAAAGTACGGTCGATCGGCCAACGTACCTCAATCAAAACATCATCTATTGCGATAACGATCGGCCGGAAGGATCGACGACGAACTACACGACGAAGCGCTATCCACCGCCGCAAAAGTTCAAACCGCACAACTGCGGACCGGACTGTCTGTACAAATCGTCGTTCGATATGCGCTCGTTCAGTCATCTCGGTAAACCGTTGCTCTGTGGCTGGGAGCGACAGGTTTGCAAATCTCGCTTCAAGAAGATGCCCAGCGTGGTGTACCGGGGTCCGTGTGGTCGCCGTATGCGCTCGATGGCGGAGGTGCACCGTTACCTGCGCATCACCAAGGCAACGCTGAACGTCGATAACTTTGAGTTCGATCCACAGCTGCGAGTATTTGCGGAGTACCGGCCCCAGTACCTGGTGGTCGACATACCGGACGTTTCGAATGGGCTCGAGTATACGCCCGTTTCGTGTGTGAACTACTTCGACGATACGAAACCGCCGCCATGCGAGTACTCAACCAAGCGCATACCCACCGAGGGCGTGGACCTGAATTTGGATGAAAATTTTCTGGTCTGCTGTGATTGCGAAGATGATTGCTTCGATAAAAGCAAATGCCAGTGCTGGCAGCTGACGATCGAGGGCGCGAAATTTCTGGCACCTGAAcaaccgatcgattcgatcggcTACGTGTACAAGCGGCTGGAGGAATCGGTCATGACCGGTATCTACGAATGTAACGCACGGTGTAAGTGCAAAATGGATTGCCTCAACCGAGTCGTCCAGCACCCGCTGCTCACGAAGCtacaaattttcaaaacaagcAACAGGGGCTGGGGTATTCGTTGCCTCAATGACATAGCCAAGGGCAGCTTCATCTGTGTGTACTCCGGTCACCTGATCACGGACGAGGCAAGCAACCAGATCTGCGCCCAGAACGATGACCAAACGGGTGACGAGTATTACGCCGAGTTGGACTACATCGAAACGGTGCAGAACACAAAGGAAGGCTACGAGAGCGATGTATCGAAcgttgaggaggaggaagaggaagatgagtTACAGGATAAGAACAGCCAGAACGAGGATTCCGACTCCGCCCTCGAAACTAGCAATCTGGAACACGATTCGGATGAAGAATTCACCTACAACAGCAGATCATCGCGCAAGACCATGGCAGTCAAGACACGGTCTCAGATTCGAAAGCTGGTAACGGAAACACAGGATGATGAGCTGACcggagagaaacaaaaggaaaaggattccgGAGAGCGCGAACCAATCAATTTCGCCCCCAACATGGAAATGTCGCGTGCGGAGGCGCTGGGTAAAGctaagaaaaggaaatctcTTCGCGAATACTACGGAGAGAACGAAGCCACCTACATTATGGACGCCAAAAAGTCGGGCAACCTGGGCCGCTATTTTAATCACTCCTGTGTACCTAATCTGTTTGTGCAGAACGTGTTCGTCGATACGCACGATGCCCGGTTCCCGTGGGTGGCCTTCTTTGCGCAGAAATTGATAAAGGCCGGCTCGGAGTTAACGTGGAACTACAACTACGATGTCGGGTCGGTGGCCGGCAAGGTACTCTACTGTCACTGCGGGGAAAAGGAATGCCGTAAACGTTTGCTTTAA
- Protein Sequence
- MDSEAAKKAEGETETILLESDDETETAALPTSMEKSEAAPATADEPAKSNIETPEAALRKPPETPKELEKVAETPAAEQHEEDVILIVDDDKEPDNPVQADEPISEQPSTAVEPQPANCIAEDSTVTDALASQIGKLCTTENGQDIVNESADEKMKEDAQEQENAEAPSEAEQQHNDEEQAKLQEGEDAFEMLVEAAIENIAAAVDGNFELEPGEDVDVKVDADAVKVEQVKPEPALPRSDCCNLECSSTCREYVEAPLFAINFYDVSKKKKKVPLLCTDCFGAVISEYENYCSMIVNQTPVVRNDRTKKEVVEIIDSDDDEDKEKIDLQKCQNETPLHQDIIALVESELEDVIKETFDKYKIHEQVEESFDYIKKIIAKNEECSKYLEPAMKQMSKKADEHLFAIYAARKIERKHLPELIIDDDLNSDIHRREPITQSHVYYASGDKLFAKWNECRIIDKVKRNNELMYYIKFLQPEGSPLQLRSSKCIAYRTAPIGKLMLGTRVIAKIDSYVGKGGSVQDAFYPGVVAESLGSYNRHRYLVFYDDGYAQYLPPKDVRVVCSQSKNVWEDVDIHSREFIKDYLIKIHKIRPMVHVKPQQRLMTERNATWYDTVVTRLDASLIEVYFVALKRHEWIYRGSTRFAPLFYGMGQHQFGNKKYSKLQQRNEPSIEYMTIDDDDDDDEKCSDGKDGTAKSSCDITGQRAEPSPTSQDNHRSKEARSDNGGKAKPTQTARKSTVDRPTYLNQNIIYCDNDRPEGSTTNYTTKRYPPPQKFKPHNCGPDCLYKSSFDMRSFSHLGKPLLCGWERQVCKSRFKKMPSVVYRGPCGRRMRSMAEVHRYLRITKATLNVDNFEFDPQLRVFAEYRPQYLVVDIPDVSNGLEYTPVSCVNYFDDTKPPPCEYSTKRIPTEGVDLNLDENFLVCCDCEDDCFDKSKCQCWQLTIEGAKFLAPEQPIDSIGYVYKRLEESVMTGIYECNARCKCKMDCLNRVVQHPLLTKLQIFKTSNRGWGIRCLNDIAKGSFICVYSGHLITDEASNQICAQNDDQTGDEYYAELDYIETVQNTKEGYESDVSNVEEEEEEDELQDKNSQNEDSDSALETSNLEHDSDEEFTYNSRSSRKTMAVKTRSQIRKLVTETQDDELTGEKQKEKDSGEREPINFAPNMEMSRAEALGKAKKRKSLREYYGENEATYIMDAKKSGNLGRYFNHSCVPNLFVQNVFVDTHDARFPWVAFFAQKLIKAGSELTWNYNYDVGSVAGKVLYCHCGEKECRKRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092163;
- 90% Identity
- -
- 80% Identity
- -