Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.22 4.9e+03 -2.6 0.1 30 37 17 24 6 24 0.65

2 3 0.066 1.4e+03 -0.9 0.4 29 37 31 39 27 39 0.75

3 3 5.1e-27 1.1e-22 79.5 0.1 1 51 52 103 52 104 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.22	4.9e+03	-2.6	0.1	30	37	17	24	6	24	0.65
2	3	0.066	1.4e+03	-0.9	0.4	29	37	31	39	27	39	0.75
3	3	5.1e-27	1.1e-22	79.5	0.1	1	51	52	103	52	104	0.97

Coding Sequence: ATGCCGAAAACGAAAGAGTACGTGTCGACCGATGATGACAGCAGCGAGgagGAGGTGAAGCCAAAGAAGAAACCAAAGAGGGAGAGCGAAGAGAAGGAAGAAAAGCCAGCGAAGAAGCCTAAGAAAGAATCTACCGAGGACGAAGATACTGTTTGGGATCTTGGAAATAACCGTCAGATTAGTGTACGGGACTTCAAAGGGAAATTGTACGTGGACATTAGAGAAATGTATTACGACAAGGATGCGAATTTGAAGCCCGGAAAGAAAGGAATCTGCCTCAGCATGCCGCAATGGCGAAAATTATTGTCCGCTGTGGAAGATGTAGACAAACTCGTCAAATCCAAATGTTAA
Protein Sequence: MPKTKEYVSTDDDSSEEEVKPKKKPKRESEEKEEKPAKKPKKESTEDEDTVWDLGNNRQISVRDFKGKLYVDIREMYYDKDANLKPGKKGICLSMPQWRKLLSAVEDVDKLVKSKC

Sequence clustering based on sequence similarity using MMseqs2