Basic Information

Insect: Anastrepha fraterculus
Gene Symbol: L
Assembly: GCA_037575425.1
Location: JAYXIM010006598.1:106339-119050[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 6.7e-06 0.00092 20.8 1.7 1 23 145 167 145 167 0.98

2 19 0.56 77 5.3 5.8 1 23 173 195 173 195 0.98

3 19 2.9e-07 4e-05 25.1 3.1 1 23 201 223 201 223 0.99

4 19 1.3e-05 0.0018 19.8 0.3 1 23 229 251 229 251 0.98

5 19 0.72 99 5.0 1.5 2 23 315 338 314 338 0.90

6 19 0.0055 0.75 11.6 0.1 2 23 367 389 366 389 0.96

7 19 0.11 15 7.5 0.9 1 23 481 503 481 503 0.97

8 19 0.57 79 5.3 2.3 2 23 511 532 510 532 0.94

9 19 0.00044 0.061 15.1 0.1 1 23 540 565 540 565 0.89

10 19 4.1 5.7e+02 2.6 0.1 1 19 570 588 570 590 0.88

11 19 2.2 3e+02 3.5 0.9 2 23 601 623 600 623 0.95

12 19 0.023 3.1 9.7 4.5 1 23 660 682 660 683 0.96

13 19 0.62 86 5.2 0.3 1 23 857 881 857 881 0.91

14 19 0.0013 0.17 13.6 4.6 2 23 890 912 889 912 0.96

15 19 0.15 21 7.1 0.1 1 23 918 940 918 940 0.92

16 19 0.023 3.1 9.7 0.3 2 23 948 969 947 969 0.97

17 19 0.81 1.1e+02 4.8 1.0 2 23 1067 1088 1067 1088 0.94

18 19 0.018 2.5 10.0 0.3 1 23 1098 1120 1098 1120 0.96

19 19 0.097 13 7.7 1.1 1 23 1127 1149 1127 1149 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	6.7e-06	0.00092	20.8	1.7	1	23	145	167	145	167	0.98
2	19	0.56	77	5.3	5.8	1	23	173	195	173	195	0.98
3	19	2.9e-07	4e-05	25.1	3.1	1	23	201	223	201	223	0.99
4	19	1.3e-05	0.0018	19.8	0.3	1	23	229	251	229	251	0.98
5	19	0.72	99	5.0	1.5	2	23	315	338	314	338	0.90
6	19	0.0055	0.75	11.6	0.1	2	23	367	389	366	389	0.96
7	19	0.11	15	7.5	0.9	1	23	481	503	481	503	0.97
8	19	0.57	79	5.3	2.3	2	23	511	532	510	532	0.94
9	19	0.00044	0.061	15.1	0.1	1	23	540	565	540	565	0.89
10	19	4.1	5.7e+02	2.6	0.1	1	19	570	588	570	590	0.88
11	19	2.2	3e+02	3.5	0.9	2	23	601	623	600	623	0.95
12	19	0.023	3.1	9.7	4.5	1	23	660	682	660	683	0.96
13	19	0.62	86	5.2	0.3	1	23	857	881	857	881	0.91
14	19	0.0013	0.17	13.6	4.6	2	23	890	912	889	912	0.96
15	19	0.15	21	7.1	0.1	1	23	918	940	918	940	0.92
16	19	0.023	3.1	9.7	0.3	2	23	948	969	947	969	0.97
17	19	0.81	1.1e+02	4.8	1.0	2	23	1067	1088	1067	1088	0.94
18	19	0.018	2.5	10.0	0.3	1	23	1098	1120	1098	1120	0.96
19	19	0.097	13	7.7	1.1	1	23	1127	1149	1127	1149	0.95

Sequence Information

Coding Sequence: aTGTACTCAACGCACACCTCCTCAAATTACTCACCTTCTATATCAGATGGCACCTTAACGCCAAACTCTTTACAACACCAAGAACAAACAACGTCACACAACCCGCATGTACAAAGGACGCAATATTGCCCACAGCCAAATGGTAGCAAAGTTGGGAATATTGACGAAAGTGAAGTGGAGGGTAATGGAGATGTCAAAACGTCAGtgaaaaactcaacaaatataCTCGAATCTACGAAGCTAGAAGAAGATGGTGCCAACTTGGAATTGCAACACAAACGACAGACTCGCATTCATCGTCAGCACCTTTACCACCATGGAGAGTATCACAGCTCGAAAATCGTTACAAAAGTGCGGAAAATCGAAAGAGTTGCTGCAAAGTTTGATAAGTTGACAGGTGATGGCATTAACGGTAGCGGTGCTGATGGGTCTTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGGCttggttatttaaaaaagcacgaACAGAGTCATGCCGAGCATTTACCTTTTAAGTGTGATTATTGTGCTCGACTCTTTAAGCACAAGAGATCGAGAGATCGTCATACCAAACTACACACTGGGGATCGCCGATACCGCTGTCCACATTGTGAGGCAGCATTTTCTCGAAGCGATCATCTCAAAATTCACATGAAAACACACGACAATCAGAAACCATTCCAATGTACGATATGCAATCGCGGATACAATACCGCTGCTGCGTTAACGTCACATATGCAAAACCATAAAAAACAAGCAGCTATTCTAGCAGCGGGAGGAAATCCTCAAGCACTTAATTACAGTCCACGTTCTACTGGATCTGTTTCCAGTAGCGGAAGTTTTCACAAGAGGCGCTATGCCACGACATTGGCTCACACTGATGCTAAGCCAACCCGACTAGATTATCCAAAGCGACCACGAACTGTGAATCTTCTTTCCTGTAATTACTGCTCCAAGTCCGAGTTCAACTCGATTGAACAACTCAATGTACATATTCACACAAAGCATGACAAAGAAGTGTTTTCCTCGCAAAAAACACAGCCAATGGCCGCTCTTGGGGCCGCAGTTGCTGAACCAAATCCATTCCAGTTGAGATGTGAGTACTGTACTATGCAATTTGGAAATCTACCTGCGTTATTTCAACATATACGTCTCGCACATGTCGATCGTTTGGCGAGCCCAAACTCGTACTTCGAACATTTCAACCGTTTAGCTGCATCAGGGACTTTTAGTCCTCGCTTAGTGAGTGAAAAACCCACTTTGAGGGAAGAAAATACTACAAAGGAAAGTAATATTAAGGCAGAACAAAATTTACCATGCTCGGAGAACGCCAATGAGGAAAAACAAGAGGAAGAGCCCACTGACCTCAGCAAAAATAAACGCCGTTCAACAACCCCCGTTTCTCTGCAGGAGGAATCTCTTCAACCTGACATGTTTTTCTGCAATCAATGCAATGCAGGTCTGCCAGATTTTGAAAAGTTCCGTAGTCATTTAAAAACGCATATAACGCAAGGTTTAAATCTTATTTGCCACCACTGCGGTTTGGCGTTACGGGAACAATCGGAGCACGAGCGGCATGTAATCTCACATTATTTAATCTCTAATTCAGAATATATTTGTGCAAGCCCTAAATGCGACAAATCGTATGCAAAACCTGAGGAACTTCAAAACCATATGTTGGATCAGCACGCAATCCCTATGTTCAAGTGTGGTGTATGCTCTGAATTATTCGAGTCCAAAATAGCCATTCAGATGCACTTCGCTTGTGCACATTCCGTTGAAACTAAATTATTGCGATGTTCAGTCTGTATGGAATTATTCCAATCTGAGAGAGAGTTCAATACGCACGTAAAAACACGCCATCCAGGACTTAATGGACCAGTGCCCAATTCACTTCAATGTTTGTTTTGTCGAACTGTATGCGGTAATGATTTGGAAATGCATTTTCATCTCGCCGCACATGCTCGCCAATTCCAATGCCCCTCGTGCCCAGAAACTTTTCATGTGGAGTTTCTATTGGATCGACATATGCAACACCATCATACTGGCAATAATCGAGCGGCATTATCTTCAAAAGTATCCCTTGAGGAAGCTTCAATACCATCTAATATGCCGAATCAAATGAACCCTCTTTATGTGAACGCCTTACTTAGCAAAGCTCCCCAGATGCCGATTTCTTCGCAAAACAACAACTCTAGTGTTCTTGATTACAATATAGCTTTTGCAGCTCATCTCAATAAAAGCCTTTTTCCTGGTTCCACGGCATCAGCAACTCCATTCACAGACGACAAATTTTATAATGCATTGCAGGTAGATACAGGAGCCGTGAAACACCCTGGGCTCATGTATGGCCTCAGCCAGCGCTATTTCGATACAAGTCGAACACTAATTGAGATGTATACGCAGCAACGAATAGATAAACCAATAGTGGAAAGCTATTTCAATAGTCCGAAGCCGCAATCCGTTACACAGCATTTAAAATCTCAACCAGATTTACATGAAAATCGACCGCCAGCAGAATCGTCAAATCCAACTTCGGTTGGATTGAACTCTTCCATGGGTTATAGCTGTGATATTTGCGAACGCAATGATTTTCGATCTGAAAGTGAGGTGAACTCACATCGTAAAATCGTCCATAACATGAAAACTGGAGTGAGTTTGCGATGCGCCTACTGCTCGGGGAACTTTAAGTCACGTAGCGAATTGGAACATCATATGAAAACGTGTCACAATTCAACTGGAAAACATAAATGTCTGATTTGTGATGAAATTTTTCCCTCGTCAGCTATATTGGCAGAACACAAACTACAACACTCAAAGGTTGGTCAATCTGGCAAATGTTCACACTGCAGTAAGCCCTTGGACGGCGCTTCAGCTTTCAAAGCACATCTTAATGACCATAACAATGAGAGCCAACTTCCAATGCAATGTATTTGCTGTCGACAATCACTTCATTCCGATTTTGAAATCGGTTTACATGCACAATTCCATACCAAATCCTCCAACAATCCAGAAAGTGTGTGTGCTCTTTGCTTAGAACCCATACCAAATCCCATGAATGGCGAAGCTAAAGTCTGTGAAAAGTGCTGCCGAAAGCATAAACTAGGCCCTAAATTTAAAACTCAACGTTTACGTAGCGAAATTTTTGAACGTGACTCAGAGATTTGTCGAAGCGCATTAAAAACCGAAAATCGCTGCAATATCTGCAAATTAATGCTGCCACACACACAAAAACTACAAGAGCATTTGGTAGAGCACACTTTTGCCGGTTGTGAGGAACGGGGTTTCAATTGCTACATATGCTCCGCCGTATTCACAGCCCCAACTGGCCTACTATCCCATATGCATGAGCATGGACTGCAGTCTCGCCCTTACGACTGTAACATTTGCACCGATAAATTCTTCTTCCGCGCTGAATTGGAACATCACCTGCTAGCCCATGAAATCCAAGATCCGATAGAATTACGAAATATATTAAGCAGTAACGACAAGTTCTCGTTACCAAGAGAGAGTAATAATTCCGAGCCCTATTTAGCAGAGGTTAAAAAGGAAATACTTCTTTCCGATGATAAGGCGACAACAGGTGAAGAGGATGAgtacattgaaattgaaaatgtatCCGATGCAAATCAGATGTATAATCAGACACAGCAATCTTACATCACCCATAAGGAAAGAATACAATTGGAAGACTCGAAGCAACTATCACCACattga
Protein Sequence: MYSTHTSSNYSPSISDGTLTPNSLQHQEQTTSHNPHVQRTQYCPQPNGSKVGNIDESEVEGNGDVKTSVKNSTNILESTKLEEDGANLELQHKRQTRIHRQHLYHHGEYHSSKIVTKVRKIERVAAKFDKLTGDGINGSGADGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAAILAAGGNPQALNYSPRSTGSVSSSGSFHKRRYATTLAHTDAKPTRLDYPKRPRTVNLLSCNYCSKSEFNSIEQLNVHIHTKHDKEVFSSQKTQPMAALGAAVAEPNPFQLRCEYCTMQFGNLPALFQHIRLAHVDRLASPNSYFEHFNRLAASGTFSPRLVSEKPTLREENTTKESNIKAEQNLPCSENANEEKQEEEPTDLSKNKRRSTTPVSLQEESLQPDMFFCNQCNAGLPDFEKFRSHLKTHITQGLNLICHHCGLALREQSEHERHVISHYLISNSEYICASPKCDKSYAKPEELQNHMLDQHAIPMFKCGVCSELFESKIAIQMHFACAHSVETKLLRCSVCMELFQSEREFNTHVKTRHPGLNGPVPNSLQCLFCRTVCGNDLEMHFHLAAHARQFQCPSCPETFHVEFLLDRHMQHHHTGNNRAALSSKVSLEEASIPSNMPNQMNPLYVNALLSKAPQMPISSQNNNSSVLDYNIAFAAHLNKSLFPGSTASATPFTDDKFYNALQVDTGAVKHPGLMYGLSQRYFDTSRTLIEMYTQQRIDKPIVESYFNSPKPQSVTQHLKSQPDLHENRPPAESSNPTSVGLNSSMGYSCDICERNDFRSESEVNSHRKIVHNMKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSSAILAEHKLQHSKVGQSGKCSHCSKPLDGASAFKAHLNDHNNESQLPMQCICCRQSLHSDFEIGLHAQFHTKSSNNPESVCALCLEPIPNPMNGEAKVCEKCCRKHKLGPKFKTQRLRSEIFERDSEICRSALKTENRCNICKLMLPHTQKLQEHLVEHTFAGCEERGFNCYICSAVFTAPTGLLSHMHEHGLQSRPYDCNICTDKFFFRAELEHHLLAHEIQDPIELRNILSSNDKFSLPRESNNSEPYLAEVKKEILLSDDKATTGEEDEYIEIENVSDANQMYNQTQQSYITHKERIQLEDSKQLSPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00083398; iTF_00082379; iTF_01189849; iTF_00091678;
90% Identity: iTF_00083398; iTF_00082379;
80% Identity: -