Basic Information

Gene Symbol
-
Assembly
GCA_963565655.1
Location
OY751428.1:3299640-3308054[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 6.8e-06 0.00057 20.3 1.0 1 23 218 240 218 240 0.98
2 30 0.0029 0.24 12.0 1.9 1 23 263 286 263 286 0.96
3 30 0.00025 0.021 15.4 1.0 2 23 293 315 292 315 0.96
4 30 0.00024 0.02 15.5 0.5 1 21 335 355 335 356 0.95
5 30 0.01 0.85 10.3 0.1 3 23 452 472 450 472 0.93
6 30 0.093 7.7 7.3 0.1 1 23 478 501 478 501 0.86
7 30 0.00013 0.011 16.3 0.1 1 23 564 587 564 587 0.96
8 30 0.0078 0.65 10.7 0.5 1 23 593 616 593 616 0.96
9 30 0.16 13 6.6 1.9 1 23 629 651 629 651 0.97
10 30 3.8e-05 0.0032 17.9 1.0 3 23 692 713 690 713 0.95
11 30 0.28 23 5.8 1.1 2 23 771 794 770 794 0.94
12 30 3.4 2.8e+02 2.4 0.0 2 23 803 825 803 825 0.84
13 30 0.65 54 4.6 0.0 2 23 832 854 831 854 0.91
14 30 1.4e-05 0.0012 19.3 1.2 1 23 862 884 862 884 0.98
15 30 0.22 18 6.1 0.4 3 23 916 938 914 938 0.84
16 30 0.00023 0.019 15.5 3.3 1 23 941 964 941 964 0.97
17 30 0.0028 0.23 12.1 0.2 2 23 971 993 970 993 0.95
18 30 0.0035 0.29 11.8 5.1 1 21 1019 1039 1019 1040 0.95
19 30 0.0029 0.24 12.0 1.8 2 23 1054 1075 1053 1076 0.93
20 30 0.23 19 6.1 0.9 1 23 1079 1102 1079 1102 0.94
21 30 0.0042 0.35 11.5 2.0 2 23 1109 1130 1108 1130 0.95
22 30 1 87 4.0 0.2 2 23 1138 1160 1138 1160 0.95
23 30 3.9 3.3e+02 2.2 0.0 2 23 1167 1189 1166 1189 0.87
24 30 0.24 20 6.0 2.7 2 23 1198 1220 1198 1220 0.96
25 30 1.4 1.2e+02 3.6 0.9 2 23 1226 1248 1226 1248 0.92
26 30 0.074 6.2 7.6 0.2 1 23 1305 1328 1305 1328 0.95
27 30 0.00036 0.03 14.9 1.1 1 22 1353 1374 1353 1374 0.95
28 30 0.53 45 4.9 1.3 2 23 1473 1495 1472 1495 0.94
29 30 0.18 15 6.4 1.4 2 23 1502 1524 1501 1524 0.94
30 30 0.75 63 4.4 2.5 1 23 1535 1557 1535 1557 0.97

Sequence Information

Coding Sequence
ATGGAGTCAAGGGAACGTTACGACGAATTGTGCAGGCTGTGTGCCTCATATGATGCTGTTAAAATGGATATATTCGGTAAGGAAGGAAAGAATCGTCAGCTAGTCGACAAAATCCAGACGTGTCTTCCCTTCAAGattgcTGAGGATGATCGACTACCAAAGTGCTTGTGCTACCGATGTATGTACaatcttgaaaatttttacgaCTTCAGAACGGCCTGTGTTAATGCAGTTGCATTATTGGAACGATCACTACCACCTACTGAATCCAAAAATGGCCAGGTTCAAAATGACATGGAAAAACATTCAGAATTACGCTCTGAGTTACtcaaggagaaagaaaaaatgccAATTTTGATACCAGAGGCTCCAATTGTCAATCCAAATGCTGCATTGGGTACTCCTCCTCGATTGAACTCTGACGGAGAGGCAGATCCAGAGATTGAGGAAGTCATGGATCAAAGTGGAACAGAAGAGGGAATGGAAGACACAGAGGATAGGAAATCTGATGAATACGAGATGGATATGGAGACAAATCCCAGTGATTTCTTGGAGATGCCACCGATGGTTACAGATGATTTGGAAGAGCCACagaatcataattttaatacaTCCGCTGTCTTTCAACACACATCAGAGCAACACGAGGTCTACGTTTGTTCTCTCTGCAACAAGGCATTCAGCTCCAAGGGTCACCTGTCACTTCATGCACGTATTCACGTGGGTGCTGGAGACGTAATCGGCTCGAAAGTAATCACTGATGATCACACATCCTATAAACGTCCATATCAGTGTGATTTGTGCAACAAATCTTACTCAACAGCCAAGCACAGGTGGGGTCACGTATCAACGACTCATCGGGGCCATCCAGCAGTCACATGCAGATACTGCTCGAGAATTTATTCAACGAGAACTAACCTTGAGGAGCACATTAAATCTAGGCACACTGGtttaccaccaccaccagaaTTACCAGTACCTTATGTACAACAAGACACTAGATATCAATGTAAAACATGTCCGAAAATGTATACAAACGTCACTGATCTCAACAAACACAGCAGAATTTGCTTGGGAGAACGTCAGAGGGAATTAACGAGTCGTCCTCCTCCAGTTCAACCAAAGGGAAGAAGTCTCATGGATACTTCAGATATGTCGAGCTTGGAATCGGACGAGGAGAATCGAGAGTACAGAAATGCTGAAGccaaattatcgaaaaatccacaattaacTATTTTGAAGCAAGCTCTAACAAGAACTGATGGTTTAAAacgagatgagaaaaattctccttACAAAACTATGAAGACCATTAAAACTGAGAATGAACAGGAGAGCACGAAAAAATGGTTCTGTGAATTTTGTCCACAGAGTTTTACTTCGGTTGATGCACTGAAAGAGCACGAAGTAGTTCATGAATCTGATAAACCTTATATTTGTATTCTTTGTGAGAAAGATTTCGTTCTGAAGTCATCATTGAGTCGTCATATTGTCGCTTCACATGGTGTTGATCCTGTGCCGATAATTGACAGTGACACTtgcttgaagaaaaatattcttcataaaaCGAGAATCGAGGAATTAAAACGTGAACCACCAGCATCACCATTTTCACCAGACAGACAATTAGATAATGAAGAGGATGATCCAGAGAGTAGAGATGATAATATGATTGAAATTGAAACTGTATTTGTTTGTGAAATATGCACGAGGGATTTCAATGATCGTGCTTCACTCTGGTTACACATCAGAGCAACGCACAAAGAATTTGCTGCATTTGCCTGTGGCGTTTGCTTGAAAATATGCTCTGATAATGAACAATTGTTGAATCACGTTAATATGTATCATGGTGGCTCAAAGCTTTTAGTATCAGAACAAAGAAGATACAGTTGTACAATATGTGGGCGTCAGCATGATtccaggaaaaaattgatgacgCACGTTTCAATTCACAATATTGATCCTAGCTACGACCCAGCGAATTTTGTCCAATTAAACAGTAATTATTACAACGAAAATTTAAATACAGAGCAAGATGGTGATTTTGATGCTGAGGATGGGGAAAAAGTTAACTGTTATGTCTGCAGAAAATCATTTCCCAATGAGGATCACTTGATACGTCATCAGAGAAATGCACATAAAACTGATCAATTGTTGGGTGAGCCTTCAGCAAATGGTGGAGTCAATCCAAATGGTAATAAAGCACAGTATCATCTATTCTTTGTTTGTGAACTCTGCGGCAGTTCTCATCCATCAAAATGGGAGAGATGGCTTCACGTGAGCAGTATCCATGGTGATGAACCAACGATAAGATGCGAACGTTCAGATTGTGCCAAGATATTCGCTACAAAGTCATTGAAGAATGAACACGTACAGCATCACATGCTGCAGGGCTCCTCGCCAAATACATGTGAAATATGTGGGAAATTATGGGGCAGTAGAGTTGATTATTGGAAGCACGTGATGGGGGTACATGCTGATACAGTGCCATTAATTTGCGGTGTATGCTTGAAGGTATTTCCAGATGTTATGCAACTCAGTGGCCATGTAAAGGCCAATCATTGGCCATTAACAAATGGTGATTTTAGTTGTGATATTTGTGGACGTCCTTACTCGAATAAATCGAAAATGTCAAGAcatcgaaaaattcatggattggACGGTGATGGATTTAATAATGGTAtaaatgaatcaataaatgaTTCTATGAATTTAGAGCAGAGTCCACCAGAAGTTGATCTCACTTGTGAAATGTGTGCTGATGTTAATTTCTCATCTTGGGAGGATCTCTGTAATCATCGTCGACTAATTCACGCTCTATTTCCATGTGATTTGTGTAATAAATGTTATGGCAGAACATCTCATCTCTGGAAGCACGTTAATCGAGTTCACAAAGGCCACAAGGACGTAACTTGTCCCTATTGCATGAAGACGAGTGCTTCCAAGGATCATTTAGCAGCGCACATTGCTAAAATTCATCGCTACGAGCCAGAGACAAAGCAGAACAAGGAGTCAACGAATTATCCATCACCCAGTGCTGAAGAGGAAACCATTCATCACTGTGAAAAGTGTAATAAAGGCTTTCACAAACGTTATTTACTCAGACGTCACATGAAAGGCTGCCAGAATTATCGTAAAGATCCTGGAGCATTGCTGACACGTTGCAGAGCTTGTGAGAGAATATTCAAAGATCGTGCAAGCCTGCAGAAACATATCGAGAATCATCACAGCAGTTATACTTGTCATTTGTGTGATGAAACCATCACGTCTAAACTTGGTATAATGACACACAATAGAGTCAATCATATGCATCATCCCGATTTAACTTGCAGCAGTTGTAAGAAGCTTTTTAGAACTAAAGAGGATTTAGAATCACACAAGAAAGATCACAAATATCATAATTCACCGAATGTCTGTGATTTTTGTGGTGATacagttgaaaataaattaaaattaaaaatgcacATTCTATCACTTCATAGAAATGAAATTGGAGTTTCATGTGGTGTTTGTTTGATTCCAATGAAGGATCCAAAGGATCTGAAGAAACACGTTGAGGATGTACATGCTGGAATACTTTTAAAGCCTAATACTTGTCAAGTTTGTGGTAAACAGTATGCATCAAAGTGGAAGGCATTTGATCACACGAAAAAGTGTCATGGAAAAGTATTCAGAACTTGCAAACAATGTTTAGCAGTTTTTACGACTGATTCAGATATTAGATATCATTATGAGCACATTCACAATGTTCCAAAGGATCAATTATCTGGCTTTGAGAATCACGTTGAGTTAGCTAGTAAAACTGATGAGCCAGTAGCTGTTAAAGAGGAGCCTGAGGATTTAGAATACGAGGATGGTGTATATGATGATAATCCACATGTACCAGAGTCAAAACGCAAGAGAACAGATACATTTGATTGTGAAATTTGTCCAGAAATATTCCTAAATCAACAAACACTATCAGAGCACTACAAAAATGTCCACAACAAAGATCCTGAGAGAAtgtttaagaaaattaaaactGGCACAAAGAAACGAATGAGAGCTCGTGAGAattttgaatgtaaaaattgcACCAAACAATTTAGTACAAAGACTCTATTCTGGAATCACATAGAAACATGTACACGAAGAAGTTCAAAGGATGAAACTAGACCTAGTTACTCATCATCAATTCTAGAGTCtcatttaaagaataataatcagATTAAGAAAGAGCCTGTTGATACAACTGCTAATGAAACTAATCTCAATATTCcagattttaatttattcgaagatattaatcttcaattatctGGACAAAAGGCAATACCAAATTTGATGCCATTGTCTCAGGTAAAAATTTCCCAAAACATGAGATGTTACAGGAAGGATTCGAGAAAGGTTTACGATGAATCAACGAATACTGTGTGTGCCTGTGAAGTTTGTGGCAAACAGTGGCCAGCTAAGAAGCATCTCTGGCAGCATTTGATACGTTTTCATCGTTCAGAGGCTGCTGTTACGTGTGGAGTATGCTTAAAATTATGTACAACATACAAAAATCTTTCTCAGCACTTGAAAGATGCACATGAAGCTATATTATCATGTGAAGGGAATAATTTCACATGTAAAACGTGTGGAAGATATCACAATGCTAGAAGTAAACTCCTTCTTCACATGAGCATtcacattaataataatgagcaTATCTGGTGTCAGAAATGTGCAGCGAGTTTTGATTGTCAGGAGAAACTGGAGCAGCATGCTAATAACTGTATTGTTAAGCGGAAAGAGGTGGAATTCGAGGAACCTGGAGATGAGATGGATGAGGAGATGATAAAGCACGAGAATGAAGAGGACAAGGGCAGTTTAATTGGAGATGGTGCATCACTCATGGAAGAAGTTGAGGAAGACGTGGATTTTGACTCTGAACCAGATGCCAGtgaaaatggagataattCAGGGCAATCGGAGGATTCAGGTGGGAGCAGTGACTCTGGAACTGAGAATGAacatgaagagaatgaattaGAGTCCAGAGCTAATAGCAGAGTCACTGGAGACGTCAGTTGCCACACTGACACTGAAGAGAGAGACTCAGATACACCTGAGCCAATTTCTGAAGTACCTGAAGAGCAGAACAAGTCTCCGAAACCCGATGAATCTAAATCCAGTGAttctaatgaagaattaaagcACAATGAcgttaaagaaaataaaaaatccgatAAGAGAGATAATGTTAAAGAATCTAATGAGACTAAATCAGAGATTGGGGAAAAGTCTCAGGATGATTCTGATGACGAGGGACCTCCTATTTTAAGTCCCATGATGCCATTGCCTCCTGAGAACGAGTCTGAGGAGCCTCCTGTCTCTCCGGAAGGCGACAAAGATGAAAACAGTCAACAAGAGTCATTGAGCATTAAAGAAGAAgctgaggaagaggaagaagaggaggacgAGATTCCTGAGCTCGATGgaatggagaataatgaaaaagaacctCTATCACCAAATTCTAATGTCGTTGATTATGAGGAATACTCTTCGACAGCTAAATCAGCAAGTGCAGCTGAGGAAATAGAGTCTGgggatgaaattgatgatgatgacagtAGATTGCAGATTGACCAAGCAGCTGAGGGCGATGGTAAAGGCTCTGAGGAGAGTGAAAGTGTCAGGGGACATGATGAAGAGGGTGAAGAGATGTTTGTAGATGAAGATGGGGAAATTGAAGAGGCTGAaggagaggaagaagagggaaaTGAAGTGCAGATAGAGGGCTTGGATGGTACTGTTCTCATGGTTGCGAATGATGCTGATGGCAATCAGATTCTAATACAACGAAATGTATCGGAGATGAGTAATGATTCGATGGGCGAAGTTGGCTTTATTTATCAGGAGGAGAATggaaatgaagatgaagagcAGGAAGAGGCTGAAGAAGAGGATGATGCAGAACAGGGTGAAGAGGGGGACGATGTTGAAGAGGGATACAGTAATGATGTTgttaatgaagaagaagatgaGGAAATGGAGATAGATGAAGCTGAAAAGACTGGAGAAGAGGGGGATGACACTGATGATAATTTGAGTGCCAAAAATAATGTGTCAAGGACGTAG
Protein Sequence
MESRERYDELCRLCASYDAVKMDIFGKEGKNRQLVDKIQTCLPFKIAEDDRLPKCLCYRCMYNLENFYDFRTACVNAVALLERSLPPTESKNGQVQNDMEKHSELRSELLKEKEKMPILIPEAPIVNPNAALGTPPRLNSDGEADPEIEEVMDQSGTEEGMEDTEDRKSDEYEMDMETNPSDFLEMPPMVTDDLEEPQNHNFNTSAVFQHTSEQHEVYVCSLCNKAFSSKGHLSLHARIHVGAGDVIGSKVITDDHTSYKRPYQCDLCNKSYSTAKHRWGHVSTTHRGHPAVTCRYCSRIYSTRTNLEEHIKSRHTGLPPPPELPVPYVQQDTRYQCKTCPKMYTNVTDLNKHSRICLGERQRELTSRPPPVQPKGRSLMDTSDMSSLESDEENREYRNAEAKLSKNPQLTILKQALTRTDGLKRDEKNSPYKTMKTIKTENEQESTKKWFCEFCPQSFTSVDALKEHEVVHESDKPYICILCEKDFVLKSSLSRHIVASHGVDPVPIIDSDTCLKKNILHKTRIEELKREPPASPFSPDRQLDNEEDDPESRDDNMIEIETVFVCEICTRDFNDRASLWLHIRATHKEFAAFACGVCLKICSDNEQLLNHVNMYHGGSKLLVSEQRRYSCTICGRQHDSRKKLMTHVSIHNIDPSYDPANFVQLNSNYYNENLNTEQDGDFDAEDGEKVNCYVCRKSFPNEDHLIRHQRNAHKTDQLLGEPSANGGVNPNGNKAQYHLFFVCELCGSSHPSKWERWLHVSSIHGDEPTIRCERSDCAKIFATKSLKNEHVQHHMLQGSSPNTCEICGKLWGSRVDYWKHVMGVHADTVPLICGVCLKVFPDVMQLSGHVKANHWPLTNGDFSCDICGRPYSNKSKMSRHRKIHGLDGDGFNNGINESINDSMNLEQSPPEVDLTCEMCADVNFSSWEDLCNHRRLIHALFPCDLCNKCYGRTSHLWKHVNRVHKGHKDVTCPYCMKTSASKDHLAAHIAKIHRYEPETKQNKESTNYPSPSAEEETIHHCEKCNKGFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHSSYTCHLCDETITSKLGIMTHNRVNHMHHPDLTCSSCKKLFRTKEDLESHKKDHKYHNSPNVCDFCGDTVENKLKLKMHILSLHRNEIGVSCGVCLIPMKDPKDLKKHVEDVHAGILLKPNTCQVCGKQYASKWKAFDHTKKCHGKVFRTCKQCLAVFTTDSDIRYHYEHIHNVPKDQLSGFENHVELASKTDEPVAVKEEPEDLEYEDGVYDDNPHVPESKRKRTDTFDCEICPEIFLNQQTLSEHYKNVHNKDPERMFKKIKTGTKKRMRARENFECKNCTKQFSTKTLFWNHIETCTRRSSKDETRPSYSSSILESHLKNNNQIKKEPVDTTANETNLNIPDFNLFEDINLQLSGQKAIPNLMPLSQVKISQNMRCYRKDSRKVYDESTNTVCACEVCGKQWPAKKHLWQHLIRFHRSEAAVTCGVCLKLCTTYKNLSQHLKDAHEAILSCEGNNFTCKTCGRYHNARSKLLLHMSIHINNNEHIWCQKCAASFDCQEKLEQHANNCIVKRKEVEFEEPGDEMDEEMIKHENEEDKGSLIGDGASLMEEVEEDVDFDSEPDASENGDNSGQSEDSGGSSDSGTENEHEENELESRANSRVTGDVSCHTDTEERDSDTPEPISEVPEEQNKSPKPDESKSSDSNEELKHNDVKENKKSDKRDNVKESNETKSEIGEKSQDDSDDEGPPILSPMMPLPPENESEEPPVSPEGDKDENSQQESLSIKEEAEEEEEEEDEIPELDGMENNEKEPLSPNSNVVDYEEYSSTAKSASAAEEIESGDEIDDDDSRLQIDQAAEGDGKGSEESESVRGHDEEGEEMFVDEDGEIEEAEGEEEEGNEVQIEGLDGTVLMVANDADGNQILIQRNVSEMSNDSMGEVGFIYQEENGNEDEEQEEAEEEDDAEQGEEGDDVEEGYSNDVVNEEEDEEMEIDEAEKTGEEGDDTDDNLSAKNNVSRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00438255;
90% Identity
iTF_00047440; iTF_00046423;
80% Identity
-