Alit038259.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrochola litura
Gene Symbol
egg
Assembly
GCA_949152395.1
Location
OX424517.1:10430183-10463668[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.86 8.6e+03 -2.1 0.1 29 38 385 394 353 396 0.63
2 2 2.3e-13 2.3e-09 38.1 0.0 4 73 426 488 423 492 0.88

Sequence Information

Coding Sequence
ATGAACAACTTGCAGACTCGTCATGCCAAGCGTCGTTTGTCGTCGACCAGTGAAACTCCAGCAAAACGTCCTGCCATACCTCTTGGATATGCTCCTTTAGATGGCGGCGACTCTAAGgaGAAAGCAGCTATTCCTGGACCAGATATTAAATTAGATGACGACAAAGACATATCAGTAGTAAAACTCTCAGCGGAAGCCGCCCCGGCAGACCTGCCCCCCCCTGGAGAGATATCCCGCCCCCCTCTGCGCGTGGGCATGCCGGTCTACGCCATGAAGAATGCCTTTGGACCCTGGCTTAAAGGCAGGGTGGTGGAGATACAGCCCAAGAATACGAGTGGGgGCAACCCCTTCTCTCTGTGTCTTGTGAAATTCGACCATAAAGTCAAGACTAACGGGAAAGTATTGCAAGCAAGGTGCATCGCATATTCGGAGCCCGCTGATGTCAGAATGACTATTGgtaCTCGTCTGATTGCCCTGTTCAAGGATTCGAACAAGCGTGAATCATACTACTCGGGAGTTGTAGCTGAAATACCCAATCCAGTCAATAATTATAGATATCTAGTATTCTTCGATGATGGCTACGCTCAATACGTCCAACATCAATTCACTCGCCTTGTCTGCGAAAGCTCCCCCTTAGTATGGGAGGAAGTACATCCGTTCTCGCGGGAATTCGTCCGCGAGTACCTGCTGGCGTATCCAGAGAGACCCATGGTCAGGCTGCATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGAGTGACCCGCGTGGACGCGTCTCTCGCGCAGGTGATGTTCGTGGGCGACGGCCGGCGCGAGTGGGTGTACCGCGGCTCCACGCGCCTCGCGCCGCTCTACCTCGAGCTGCGCGCGGCCGAGCGACACCGGCCCAGGCCCATGCCGAGGAGCAAGGCGCAGCCTAGGTTCAATATGCCGTACGTGGAGTACACTCGGTCGGATGAGCCGGAATCGGGCAAGCCAGTGGATGCGCAGGCGCAGCAACAACAGCAAGAGCAGCAGCAGATACAAAATGACGAGATacgtcgccaacgcgccgtggCCAAGAAGTCCACCTCAGCACCTCCTCAAGTGCTCCCGCCTTCACAACAGATCATGCCGCCCACACACATGGATCCTGTTACCAGCAGAGTTGTGTACTACACACCAAAGAATGCAGTGaaaccattgaagatggtgccACACAGATGCGGTCCGAGATGCAAGAGGAGTGACGTACTCTCACTAAAAGAGTTAAGGACATATAACCCATTGGCAAAACCGCTGCTCAGTGGATGGGAACGACAAATAGTCCGCTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCCTGCGGCCGTCGCTTACGAAACATGCGCGAGTTACATCACTACTTACGTTCCATAGACAGCGACTTACCTGTAGATCTGTTTGACTTCCACTACTCAACGCATTGCCTCGCGGAATTCGTGCTCAACAAGTGTCTTGTGGGGAAAAAGGACCTCTCTCACGGCAAAGAGAACGTCCCAGTACCCTGCGTGAACTACTACGACGACTCCTTACCGGAGTTCTGTTCGTACAACACCGAACGCACTCCCACCGCCGGCGTGCCGCTCAACTTGGAGCCCGAGTTCTTGTGCGGCTGTGACTGTACCGACGACTGTCAgGATAAGTCAAAATGCGCTTGTTGGAAAATGACTCTAGAGGGCGCTCGAACCATTGGGCTACGTGGCCCTAATGTGGGCTATGTTTACAAGAGATTGCCTGAACCGTTACCGTCCGGAATATACGAGTGTAATTCTAGatgtAAATGCAAGCATACGTGTCTAAATCGCGTAGCGCAGCATCCGCTACAATTAAAGTTACAGGTATTCAAAACCCCGAACCGCGGTTGGGGTATCCGTGCACTGAACGACGTCCCCAAAGGCTCCTTCCTGTGCGTGTACGCTGGTAACCTGCTTACAGATGCCACCGCTAACTTGGATGGTTTGAACGAGGGTGACGAATACCTAGCAGAGTTAGATTACATAGAAGTTGTGGAGCAGATGAAAGAGGGATATGAAGAGGACATTCCTGAAGCCGATAAAAAATTAGACAAGAAAGAAGTTAAGGATGAAGACGACACTGAGGAGGATGAACCGTCATCCTCCGAGGAAGAGGAGAAGGCGGATAAGAATGACAAAGAGGATGATGACTTCAGACCGGGATACATTGGACTAGGCGTTACAGAGTTCAACAAACGTCTCCGTAAACGCGAAAAATCTAAGAAAGATAAAGAAAAATCGGTGACTGATGAGAAAGAAAAGGAGAAAGATACGACTAAAGAAGCAAATGGTGAAGAGGATTGTATTACTATCAGTGATGATGAAGAAGTACGAGAACCATCGAGATTCATGGCTCAAACAAACATGGGAGCTAACGAGTATATTTCTAAATACAAGTCTGTTCGCACGTTGTTCGGCAAGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATACCTCAATCACTCCTGCACCCCGAATGTCTTCGTACAGAACGTGTTCGTGGACACCCACGACCCTCGCTTCCCTTGGGTCGCGTTCTTTGCGCTATCACACATCAAAGCAGGTACCGAGCTCACCTGGAACTACAACTATGATGTGGGTTCTGTTCCTGGGAAGATACTTTATTGTTACTGTGGAGCTCCTAATTGTAGGGGACGGCtgttgtaa
Protein Sequence
MNNLQTRHAKRRLSSTSETPAKRPAIPLGYAPLDGGDSKEKAAIPGPDIKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVVEIQPKNTSGGNPFSLCLVKFDHKVKTNGKVLQARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLLAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWVYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEPESGKPVDAQAQQQQQEQQQIQNDEIRRQRAVAKKSTSAPPQVLPPSQQIMPPTHMDPVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKEVKDEDDTEEDEPSSSEEEEKADKNDKEDDDFRPGYIGLGVTEFNKRLRKREKSKKDKEKSVTDEKEKEKDTTKEANGEEDCITISDDEEVREPSRFMAQTNMGANEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01342242; iTF_00906179; iTF_00924708; iTF_00171781; iTF_01026214; iTF_00041802;
90% Identity
iTF_00622853;
80% Identity
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