Aips024770.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrotis ipsilon
Gene Symbol
egg
Assembly
GCA_028554685.1
Location
CM052981.1:6506565-6527853[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.1 4.9e+03 -1.8 0.1 28 38 295 309 271 311 0.65
2 2 1.8e-13 7.9e-10 39.2 0.0 4 73 341 403 338 407 0.88

Sequence Information

Coding Sequence
ATGCTGAGCTTGCGTTTCGTGCCCATAGGTGCCGTGTGCAATGTATATGCAGGTATGCCGATGCAGCGATCTATTAAGGGCAACCCGTATTCCTTTTGTCGCGTGAGATTCGACCACAAAGCCAAGACCAACGGAAAGGTGTTGAAAGCTAGTTCCGTCGCTTATTCTGACCCTGCCGATGTTAGAATGACTATTGGTACTCGTCTCATAGCTCTAATCAAGGATTCTAATAAGCGCGAAACTTACTATGCGGGCGTGGTAGCCGAAATACCTAATCCTGTCAACAGTTATAGATACCTCGTATTTTTCGACGACGGCTACGCTCAGTACGTACAACATCAACACACGCGCCTGGTCTGTGAGAGCTCGCCGTTAGTGTGGGAAGAGGTACATCAGTTCTCACGGGACTTCGTGCGCGAGTACCTGCTGGCGTATCCCGAGAGACCCATGGTCAGGCTGCACAAGGGACAGCATCTCAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGTGTGACCCAGGTGGACGCGTCCCTGGCGCAGGTGTTGTTCGTGGGCGACGGTCGCCGGGAGTGGATCTACCGCGGGTCCACCCGCCTGGCGCCGCTGTACCTGGAGCTGCGGGCCGCCGAGAGACACCGACCACGACCCATGCCCAGGAGTAAAGTACAACCTAGGTCCAACATGCCGTACGTGGAGTACACTCGTTCAGACGAGCAGTCCGAGTCTAACAAACAGACGGACACACAACCACAGACGCTGCAACAGATacagcaacaacaacagcaaCTGCAGAACGAGGAGATCCGTCGTCAGCGCGCGGTGGCCAAGAAGTCGACGTCCTCCCTCCCTGCGCCCGCGCCTCCTCCCGCGGCGCTCCCTGCCAGTGCGGACCCCGTCACCAGCAGGGTCGTGtacTACACGCCAAAGAACGCAGTGAAACCACTAAAGATGGTGCCACACAAGTGTACTCCTAAATGTAAACGAAGCGACGTACTGTCTCTAAAGGAGCTGAGGACTTACAACCCACTAGCTAAACCACTGCTCAGTGGATGGGAGAGgcaAATAGTCCGCTTCAAAGGCCATAAGGATGTAATGTACCGCGCTCCATGCGGCCGTCGTATCCGTAACATGCGCGAGCTACATCACTACCTGCGCTCCATAGACAGCGACCTGCCTGTAGACCTGTTCGACTTCCACTACTCCACGCACTGCCTCGCTGAGTTCGTGCTCAACAAGTGTCTCGTTGGGAAGAAGGATCTCTCCCACGGCAAAGAGAACGTTCCAGTCCCATGCGTGAACTACTACGACGACTCCCTCCCGGAGTTCTGTTCGTACAACACGGAGCGTACTCCCACCGCTGGGGTCCCACTCAACTTGGACCCCGAGTTTCTGTGTGGATGTGACTGTACTGATGATTGTCAGGACAAATCAAAATGCGCCTGCTGGAAGATGACGCTAGAGGGCGCTCGTACTATCGGACTGGAAGGACCTAACGTGGGATATGTATATAAACGACTGCCTGAACCATTACCTTCAGGAATATATGAATGTAACTCTAGgtgtAAATGCAAGCATACGTGTCTAAATCGCGTTGCACAACATCCGCTACAGTTGAAGTTACAGgtatTCAAAACACCTAACCGTGGTTGGGGTATCCGTGCTCTGAACGACGTGCCTAAGGGTTCATTCCTCTGTGTTTACGCCGGCAACCTACTAACAGATGCTACGGCTAACTTGGATGGTTTAAACGAGGGCGACGAATATCTAGCAGAGTTAGATTATATAGAAGTAGTAGAACAGATGAAGGAAGGATTTGAAGAAGACATTCCTGAGGCCGATAAGAAACTAGACAAGAAAGGACAAGGTAAGGAGGAGTCCAGTGACTCAGAGGAGGCCTCATCATCAGAGGGAGAGGACACCGCCTCCAAGACTGAcaaggaagatgatgacttcAGACCAGGGTTTATTGGACTGGGTGTCGCTGAGTTTAACAAACGTCTCCGTAAACGCGAGAAATCGaagaaagataaagataaaactgGGACTGACGATAAGGACAAGGAAAAAGATAACAAAGATACAAAAGATAATAAAGATGTGAAGGAATCGAATGGTGATGAAGATTGTATTACTATTAGTGATGATGAAGAAGtacGAGAACCATCAAGATTCATGGCACAGATGAACATGGGAGCTAACgactatatttctaaatacaaATCTGTCCGCACATTGTTCGGTAAGGACGAGGCGTGCTACATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGGTATCTCAATCACTCGTGTTGTCCCAACGTATTTGTCCAAAACGTATTCGTGGACACCCACGACCCTCGCTTCCCCTGGGTGGCGTTCTTCGCACTCTCACACATCAAGGCAGGCACTGAGCTCACTTGGAATTACAACTACGATGTGGGTTCGGTGCCCGGGAAGATACTCTACTGCTATTGTGGCGCTGTGAACTGTAGGGGTcgacttttataa
Protein Sequence
MLSLRFVPIGAVCNVYAGMPMQRSIKGNPYSFCRVRFDHKAKTNGKVLKASSVAYSDPADVRMTIGTRLIALIKDSNKRETYYAGVVAEIPNPVNSYRYLVFFDDGYAQYVQHQHTRLVCESSPLVWEEVHQFSRDFVREYLLAYPERPMVRLHKGQHLKTEWNGKWWSSRVTQVDASLAQVLFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKVQPRSNMPYVEYTRSDEQSESNKQTDTQPQTLQQIQQQQQQLQNEEIRRQRAVAKKSTSSLPAPAPPPAALPASADPVTSRVVYYTPKNAVKPLKMVPHKCTPKCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKDVMYRAPCGRRIRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLEGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGFEEDIPEADKKLDKKGQGKEESSDSEEASSSEGEDTASKTDKEDDDFRPGFIGLGVAEFNKRLRKREKSKKDKDKTGTDDKDKEKDNKDTKDNKDVKESNGDEDCITISDDEEVREPSRFMAQMNMGANDYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAVNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00036748;
90% Identity
-
80% Identity
-