Sver009522.1
Basic Information
- Insect
- Shargacucullia verbasci
- Gene Symbol
- egg
- Assembly
- GCA_947562105.1
- Location
- OX387308.1:2634479-2650255[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.2 3.8e+03 -2.2 0.0 29 38 293 302 262 304 0.69 2 2 8.1e-14 2.5e-10 40.1 0.0 4 75 334 398 331 400 0.89
Sequence Information
- Coding Sequence
- ATGCCGGTGTACGCCATGAAGAACGCCTTCGGACCCTGGCTGCGCGGCAGGATACTGGAGATACAGCCCAAGAACCCCAACTCGCCAAACTCATTCTCTGTATGTCGCGTCAAATTTGACCACAAAACGAAAACCAACGGCAAAGTGTTGCCAGCGAGGTGTATAGCGTACGCAGAGCCGGCTGACGTCAGAATGACTATTGGTACACGTCTCATAGCCCTTTTCAAGGACTCCAATAAGCGAGAGTCGTACTATTCTGGTGTCGTGGCTGAAATACCAAACCCTGTTAATGATTACAGGTACCTAGTGTTCTTCGACGATGGCTACGCGCAGTACGTGCAGCACTCGTTCACGCGCCTCGTGTGCGAGAGCTCGCCCCTGGTGTGGGAGGAGGTGCACCCGTTCTCCAGGGAGTTCGTCCGGGAGTACCTGCTGGCGTACCCCGAGAGACCCATGGTCAGGCTGCATGAGGGACAGCACCTTAAGACTGAGTGGGACGGAAAATGGTGGTCGTCCCGAGTGACTCGAGTGGACGCGTCTCTAGCTCAAGTGACGTTTGTCGGCGATGGGCGCAGAGAATGGATCTACCGCGGCTCTACCCGCCTTGCTCCACTGTATCTAGAGCTGCGGGCTGCTGAGCGACATCGACCCAGGCCCATGCCCAGGAGCAAGGCTCAGCCTAGGTCAAATATGCCTTACGTGGAGTACACAAGATCAGATGAGCCGGACACGAACAAGCAACCGGATACGCAAGTGCAACAGCAGCAAAATGAGGAGATACGTCGTCAACGCGCAGTCGCCAAGAAGTCAACGACGGTGGCTCAGGTGGCGCCACCTCCTCAACAACACCCAGTAGCTCCTGGGAACCTGGACACAGTCACCAGCAGAGTTGTGTACTACACGCCAAAGAACGCAGTGAAGCCGTACAAGATGACACCACACAAGTGTGGTCCAAAATGCAAGAGAACAGATGTGTTATCACTTAAGGAGCTAAGGACTTACAACCCTCTCGCTAAACCGCTGCTCAGTGGGTGGGAAAGACAAATCGTGCGCTTCAAGGGCCACAAGGAGGTGATGTACCGGTCGCCGTGCGGGCGGCGCGTGCGCAGCGTGCGCGAGCTGCACGCGTACCTGCGCGCCGTGGACAGCGACCTGCCCGTCGACCTGTTCGACTTCCACCACGCCACGCACTGCCTCGCCGAGTTCGTGCTCAACAAGTGCCTCGTCGGGAAGAAGGACCTTTCCCACGGCAAAGAGAACGTCCCAGTTCCCTGCGTGAACTACTACGATGACTCGCTACCAGAGTTCTGTTCGTACAACACGGAGCGCACGCCCACTGCTGGGGTACCACTCAACCTGGACCCCGAGTTCTTGTGCGGCTGCGACTGTACTGATGACTGTCAGGATAAATCCAAATGTGCTTGCTGGAAGATGACACTAGAGGGCGCTCGTACTATTGGGCTACATGGTCCAAACGTGGGCTACGTGTACAAACGATTGCCCGAACCGTTACCTTCTGGAATATACGAGTGTAACTCTAGGTGTAAATGTAAGCACACGTGCTTGAACCGAGTTGCACAACACCCACTACAGTTGAAGTTACAGGTGTTCAAGACGCTGAACCGCGGCTGGGGCATCCGCGCGCTCAACGACGTGCCCAAGGGATCGTTCCTGTGCGTGTACGCAGGGAACCTGCTCACCGACGCCACTGCTAACCTGGACGGTTTGAACGAGGGCGACGAGTACCTGGCCGAGTTGGACTACATAGAAGTGGTGGAGCAGATGAAGGAGGGGTACGAGGAAGATATACCGGAGGCAGACAAGAAGTTAGACAAGAAAGAAACAGCTAAAGACGATGATGATGATGAAGACGACGAGCCTTCATCATCAGACGAAGAGGACACAGCCTCCAAGACTGACAAGGAAGATGATGACTTTAGACCTGGATACATTGGATTAGGAGTTACGGAGTTCAACAAACGTTTGCGCAGACGTGAGAAATCAAAAAAAGAGAAAGAGGGAAAGCTAGGAGAAGAGAAGGACAAAGATACTAAAGAAGGAAACGCAGATGAAGATTGTATCACCATCAGTGATGATGAAGAAGTGAGAGAGCCATCGCGATTCATGGTACAAGCCGGCATGGGAGCAAACGAATTTATTTCCAAATACAAATCAGTTCGTACGCTGTTCGGCAAAGATGAGGCGTGTTATATTATGGACGCTAAGGTTCAGGGCAACATCGGCCGATACCTTAACcactcctgctgccccaacgtgtttgtccagaatgtcttcgtggacacccacgacccccggttcccgtgggtggcgttcttcgcgctatcccacatcaaagctggcactgagctcacgtggaactacaactatgacgtaggttcggtgcccgggaaggtactttactgttactgtggagcgcctaattgtagaggacggctgttgtaa
- Protein Sequence
- MPVYAMKNAFGPWLRGRILEIQPKNPNSPNSFSVCRVKFDHKTKTNGKVLPARCIAYAEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNDYRYLVFFDDGYAQYVQHSFTRLVCESSPLVWEEVHPFSREFVREYLLAYPERPMVRLHEGQHLKTEWDGKWWSSRVTRVDASLAQVTFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRSNMPYVEYTRSDEPDTNKQPDTQVQQQQNEEIRRQRAVAKKSTTVAQVAPPPQQHPVAPGNLDTVTSRVVYYTPKNAVKPYKMTPHKCGPKCKRTDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRSPCGRRVRSVRELHAYLRAVDSDLPVDLFDFHHATHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLHGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKETAKDDDDDEDDEPSSSDEEDTASKTDKEDDDFRPGYIGLGVTEFNKRLRRREKSKKEKEGKLGEEKDKDTKEGNADEDCITISDDEEVREPSRFMVQAGMGANEFISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKVLYCYCGAPNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00036748;
- 90% Identity
- -
- 80% Identity
- -