Ahol033278.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Acleris holmiana
Gene Symbol
-
Assembly
GCA_949316455.1
Location
OX438782.1:12258495-12262588[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.021 2.5 10.0 0.1 5 23 418 436 417 436 0.97
2 12 0.023 2.7 9.9 0.2 1 23 442 464 442 464 0.91
3 12 0.61 71 5.4 0.3 3 23 473 493 471 493 0.87
4 12 7.8e-07 9.2e-05 23.9 0.7 2 23 499 520 499 520 0.98
5 12 0.003 0.35 12.7 4.1 1 23 526 548 526 548 0.98
6 12 0.00014 0.016 16.9 0.2 1 20 552 571 552 573 0.94
7 12 0.00031 0.037 15.7 0.0 1 23 606 629 606 629 0.95
8 12 0.0013 0.15 13.8 0.1 3 23 638 658 637 658 0.99
9 12 3.8e-05 0.0045 18.6 0.2 1 23 669 691 669 691 0.98
10 12 0.00015 0.017 16.8 6.7 1 23 697 719 697 719 0.98
11 12 0.0034 0.4 12.5 0.3 3 23 727 747 725 747 0.98
12 12 3.8e-05 0.0044 18.6 0.9 1 23 753 776 753 776 0.96

Sequence Information

Coding Sequence
ATGGAACGAAGTATGctatacataaaaaagaaagacaGAGAGAAGCTAAGTACCATAAGAAAGAGGACTAAGGTTAAGGATATATCTGTAGCAGTAAAAAGTCTGAAGTGGAAGTGGGCAGGACACATGGCAAGAGATCCTGGAAACAAATGGAACAAAGAGGTGGCAGAATGGTACCCAAGAGATGGAACTAGGAAACGGGGAAGACCAAGCCTAAGATGGGCAGGTGATCTCAGGAAACAAGCAGGGCAAAACTGGATTGGAAAGGCACAGGATAGAGATATTTGGAGAAGGCTGGAGGAGGCCTATGCCGTGGACGCCGATGACGGACTGCCTCAAAAGCTCTGCGGGCAGTGCTATGAAACCATGAGCTCCGCCTACCAGTTCCGGAAGCAATGCATCAGGATGGACACGGAACTGAAGCTACAACTAGAGACCCTGCTGACCCAGGCTGAGGAGGGACAGGTAGATGAAACAGAGGAGGCTATAGACCAAGACTATGACGACATAGCCAACAACCCCGAGAAACAATTAGAAGCCATCATCAAAAGAGAACCAACTGACAGTGATGATGACTATTATTATGTACTAGTAATCGATGACGCAAAAGataaaaatgaaaatcaaaCTGAAGAAGATATAGCTGTTCCTAATATTAAAGCTGAGATCGTGGAACAACAAGAAACAGAAGAAGCTGCAGAGGAAACTATTAATGAACAGCATTTTGAAATTGATCAGTTCCTTATGTCTGAAACGAAAGTCCCCACAAATGTCCCTGCTACCATATTGGAGAATGAAGAAGAGAGCCAAGAAAATGAGGAAGTGCAGTATGAGAATGCTATGGAAGTTCAAGAAAATCATGAAGAAAACTCTCAAGGTTTTGATGTTATGGATGCAGATATTGAGGACtcgcaggacaatgtcacagatTTAGTTGATGCTATCACTGGTGAGATTGGAGGTGGGTTAGCCAAAACCATTAGTAAAAACAgcttcattaaaataataacaagtgGAGCAGATGGCACAATCCTCCTTAAAGACAATGTGGCTTATTTGACTGAGGCCCAGTTAGATTCAAATGAGGAAGGAGAAGCTTTATCTCAAGAAGAAGAGGTAATTTTCTGTGAAGGTGATGAATCATCACAAttccaaatattaaaatgcgaGGGTTCAGAACTTGTTATAGAATATGCTGACGATGGCCAAATAGCTACAGTTTTGCAGCAAGAAGATGGCAGCTTTCTCTGTGACTGTGGAGAACAATTTGAAGACTTAGCTGACTATGAGAAACACCAGTACACCCACAATGCTACTGAAGAGCATGTCTGTAATCTATGTGGCAAGGGCTTTGAATCTGCTGAGATACTAACAGGACACACTTTGCTCCACAATGTTACTGGGCTCCTAGTCATGTGCCCGTTCTGTAAACAGCTAATAAGAAGAAGTGCTCTCACCCAGCATATAAAATATGGCCACAACAACATTAAACCACGCTGTgatgtttgttttaaaacattcgCTAATCCTAACAATTTGAAACGTCACATGATGATCCATAGTGGTGTTAGACAATTTGAATGTGATATCTGCTACAAACGGTTCCACCAGAAAATTACCATGCAGACACATAGACTGACCCATATCAATCCGTTTTCTTGTAACAAATGTGAAGAAACATTCAGCAACAAAGCAGAGCTAGCAGCTCACAAAGAATCAGACGAGTGTACGAAATCTAGAGTGGCCAAAGTTAGAGATGAGTTGATGAAGACTGCTAAGCATGAGATCACAACCAATTTAGGCAAGCTCCTGGGATATGCCTGTGCTTTATGTAAGAAAATGTTCTCTGTAGAATCTGCACTGGAACAGCATATAGACAGTGTACATCTAGTAGACCCAAATGAACTGCTCTGCTCTGAATGCGGTGAAGTGGTCCCAACCAGAAAAGATATGCAGTCACATATATTGACTCATAAAAGTATGAAGTTAAAGAATTCAAAGCGGTTTGAGTGCGGCATTTGTGGAAAAAGCTGTGCTAGTCAGGCTATGTTAGTGATGCATGAAAGAGTTCATACAAATGAAAGACCATTTCCCTGCCATCTCTGTTCACTcaggtttaaaacaaaaacacatcTTAGAACCCATCAGCTGACTCACACCAGAGAGAAGAAGTTTGGTTGCTCGGTTTGCATGAAATTCTTTGCTCTTAAAGGTAATTTGGTGGTCCACCTTAGAACGCATACGGGCGAAAGGCCCTATATTTGCACACTGTGTGGAGAGGCCTTCATTGActctaaatatttgaaaaagcaTAAACTAAAGAAGCACTCTATACAAAACGTTCCCTGGAACAAGTACTGA
Protein Sequence
MERSMLYIKKKDREKLSTIRKRTKVKDISVAVKSLKWKWAGHMARDPGNKWNKEVAEWYPRDGTRKRGRPSLRWAGDLRKQAGQNWIGKAQDRDIWRRLEEAYAVDADDGLPQKLCGQCYETMSSAYQFRKQCIRMDTELKLQLETLLTQAEEGQVDETEEAIDQDYDDIANNPEKQLEAIIKREPTDSDDDYYYVLVIDDAKDKNENQTEEDIAVPNIKAEIVEQQETEEAAEETINEQHFEIDQFLMSETKVPTNVPATILENEEESQENEEVQYENAMEVQENHEENSQGFDVMDADIEDSQDNVTDLVDAITGEIGGGLAKTISKNSFIKIITSGADGTILLKDNVAYLTEAQLDSNEEGEALSQEEEVIFCEGDESSQFQILKCEGSELVIEYADDGQIATVLQQEDGSFLCDCGEQFEDLADYEKHQYTHNATEEHVCNLCGKGFESAEILTGHTLLHNVTGLLVMCPFCKQLIRRSALTQHIKYGHNNIKPRCDVCFKTFANPNNLKRHMMIHSGVRQFECDICYKRFHQKITMQTHRLTHINPFSCNKCEETFSNKAELAAHKESDECTKSRVAKVRDELMKTAKHEITTNLGKLLGYACALCKKMFSVESALEQHIDSVHLVDPNELLCSECGEVVPTRKDMQSHILTHKSMKLKNSKRFECGICGKSCASQAMLVMHERVHTNERPFPCHLCSLRFKTKTHLRTHQLTHTREKKFGCSVCMKFFALKGNLVVHLRTHTGERPYICTLCGEAFIDSKYLKKHKLKKHSIQNVPWNKY