Alag008206.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Acanthococcus lagerstroemiae
Gene Symbol
Hr39
Assembly
GCA_031841125.1
Location
CM063108.1:8514766-8529301[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.17 3.2e+03 -1.8 4.5 116 160 183 227 67 299 0.51
2 3 9e-09 0.00017 22.2 0.0 1 47 425 469 425 482 0.85
3 3 6.1e-72 1.1e-67 230.3 0.0 199 408 505 709 483 709 0.96

Sequence Information

Coding Sequence
ATGTCATCGATTTGGACCCGTGCTGCGCATAGCGTTGTATCCTCGGGACCGGTTACAGTGACGTCTATCAATGTCGAAGACATACCCAACACTAATGATCAGAATATCTCCATAAGTAAAGCCGAAGATTTCAGCATTAAAAAAGAAGTGCAGATGCCGGAGAACATAGAAGATGTATCAGACTCCGAAGGAGAGCTCAGCCAAATTGACTTCACTGGTGTCACGATGAGAAACAAGAAATCGAAAAACGACGAAGTTCCTAATGATAGAATCGAGCGGCCTATGTCTTGGGAAGGCGAACTATCTGACTCGGATATGAAACAAGAAAATCAAGACGGTGACACGTCCATAACGATTAGTGAGAACAATTCCTCAAATTCACGTATGGAAAATGCCGATAATGCTGATGATTCGAAGCCGGCTCCGTTAAAATTTACTACCGAAGTTACTGTGGATCAGATGACCGACGGTGTGAAAGTATGCAAAGCATCACACTCAGAAATTCCTCTACTAGTTGATAAATTATTAGGTAGCTGTTACAGTCCGGTGTTACAACACAGAACCGGAAAATCTCAGATACCGCCAACTCCTAGCCCAGACTCCGCCATACACAGTTGTTACTCGCCGACGCAGTCTCCGGTAACGAGCAGACATTTACCGTCTTCAGGCTTTTCTTCGCCATTTACACCTTCGCTTTCACGTAACAACAGCGATGCATCGCAGTATGGCGGCTCGCAGCATAGTTCTTGTTACAGTCAAAGTTACTCTTCAGTGTCAGTATCGCCGACCCAGTTTTCGCCTACGCATTCGCCAATTCAAGGTAGACACGGATATCGAAGTTCGTCGGATTTTCCATCGCACAGTGTCAATGGTACTTTGTATAATGTAAACAGACATGGTATGATGGATGATGGATCGCATATGGAAAACGGTTCAGCAAATCATACCGATGATAATAACATGTACGAAGACAGAGTACCGCCATTTACGGCCGATATGGGCCATAATTCGCCTAATTTAAGTACTTCGTCCGGTATCTCAAGACAACAGCTAATCAACAGTCCTTGTCCGATATGTGGCGATAAAATATCCGGTTTCCATTACGGCATTTTTTCGTGCGAAAGTTGCAAAGGGTTTTTCAAGCGCACCGTGCAGAATCACAAGAATTACGTTTGTCTTCGTGGTTCCTCGTGTTTAGTGACAATAGCGACTCGGAAAAAGTGTCCAGCTTGTCGTTTCGATAAATGTCTCAATATGGGAATGAAATTAGAAGCTATAAGAGTGGACAGAACCCGAGGAGGCAGAAGCACGTATCCGTTTTCGTATACGTTACCCGCCAGTCTAACCCAGATGCAGAATTCCAGTGATTCATCGGCCAATATGGTGAAACAGGAAACGCCGTCGGATGCGTCGCCCCCGTCTTCTCACTTGTCGAATGGATTCATACCGCCTTTACTACAGGAAATCATGGAGGTCGAACATTTATGGCAGTACAACGAAAACGAGACGCCGAATATCAGAACCAACACCAATAACCCGGACTTCGTTGCTAATTTGTGTAACATCGCCGATCATCGCCTGTATAAAATCGTCAAATGGTGCAAATCACTGCCTCTCTTCAAAAATATATCGATCGACGATCAGATATCGTTGTTGATCAACGCCTGGTGCGAGTTGCTGCTGTTCAGCTGTTGTTATCGGTCTGTGAGTACTCCCGGCGAAATACGGGTCAGTCTGGGCAAATCAATAACGCTGAACCAAGCCAGAGAGCTTGGACTGGCGCCGTGCATAGAGAGAATGCTGAACTTCACCGACCATTTGCGAAGACTCCGAGTGGATCGGTACGAATACGTTGCCATGAAAGTCATCGTGCTTCTGTCCTCGGATTCCAGCGATCTGAGGGAACCGGAGATGGCGAGAGCGTCGCAGAAGAAAGCGCTGCAAGCGTTGCAGCAATATACGATAGCCCACTACCCAGATATGCCGTCAAAGTTCGGTGAACTATTGCTGAGAATTCCAGATCTGCAGAGAACCTGTCAAGTTGGAAAAGAAATGCTGTCTATTAAACACAAAGAAGGAGAAGGACCTAGTTTTAACCTTTTGATGGAGTTACTTCGGGGAGATCACTGA
Protein Sequence
MSSIWTRAAHSVVSSGPVTVTSINVEDIPNTNDQNISISKAEDFSIKKEVQMPENIEDVSDSEGELSQIDFTGVTMRNKKSKNDEVPNDRIERPMSWEGELSDSDMKQENQDGDTSITISENNSSNSRMENADNADDSKPAPLKFTTEVTVDQMTDGVKVCKASHSEIPLLVDKLLGSCYSPVLQHRTGKSQIPPTPSPDSAIHSCYSPTQSPVTSRHLPSSGFSSPFTPSLSRNNSDASQYGGSQHSSCYSQSYSSVSVSPTQFSPTHSPIQGRHGYRSSSDFPSHSVNGTLYNVNRHGMMDDGSHMENGSANHTDDNNMYEDRVPPFTADMGHNSPNLSTSSGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNHKNYVCLRGSSCLVTIATRKKCPACRFDKCLNMGMKLEAIRVDRTRGGRSTYPFSYTLPASLTQMQNSSDSSANMVKQETPSDASPPSSHLSNGFIPPLLQEIMEVEHLWQYNENETPNIRTNTNNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCYRSVSTPGEIRVSLGKSITLNQARELGLAPCIERMLNFTDHLRRLRVDRYEYVAMKVIVLLSSDSSDLREPEMARASQKKALQALQQYTIAHYPDMPSKFGELLLRIPDLQRTCQVGKEMLSIKHKEGEGPSFNLLMELLRGDH