Epel032628.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ericerus pela
Gene Symbol
Hr39
Assembly
GCA_011428145.1
Location
WOFM01002315.1:42023-55177[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.042 7.3e+02 0.2 7.5 55 160 125 229 79 241 0.74
2 4 0.27 4.7e+03 -2.4 4.0 74 170 247 361 228 365 0.42
3 4 3.7e-06 0.064 13.6 0.1 1 28 431 458 431 466 0.81
4 4 1.3e-72 2.2e-68 232.5 0.1 144 408 460 715 451 715 0.83

Sequence Information

Coding Sequence
ATGTCTTCGATTTGGAGCCGTGCAGCACATAGTGTTGTTTCCTCGGGGCCGGTTACTGTAACGTCAGTGAATGTGGAAGATGTATCGGGAATGAAGGATCAGAATATTACCTCGATCACTGATGctgAAGATTTTAGTATCAAAAAAGAACCGAATATGCTTGATAACAATGTCGATGATATTTCTGATTCGGAAGGAGAGCTGAGTAAAATAGATTTTTCTGGTGTGACGATGAGAAGTAAAAAGTCAAGATCGAATGAAGTGCAGAATGATCAAGTCGAACGACCTATGTCATGGGAAGGTGAATTATCTGACTCTGAAATGAAACAAGATAACGACAATGGTGACGCATCAGTCATTGTAACAGAAACCGATTCGTCGCAATCAAGAATGGAAAATGTTCATCATGAAGATGATACTAAGCCCACACCCTTAAAATTCACCACTGAAGTTGAACAAATGACCGACAGCATAAAAGTGAACAAATCGACATCACATTCTGAAATTCCTCTCTTAGTCGATAAATTATTAGCTGGTAGTTGCTATAGTCCAGTGCTGCAGCATCGTACTAGTAAAACGCAAATTCCGCCTACTCCTAGCCCTGATTCTGCCATACATAGTTGCTATTCGCCTACGCAATCACCTGTTACATCCAGGCATTTACCCTCATCTGGATTTTCATCTCCATTTACACCTTCCCTTTCTCGTAATAATAGCGATGCTTCTCAATACGGAGGATCTCAGCATAGTTCATGTTACAGTCAAAGTTACTCTTCCGTGTCAGTGTCTCCTACGCAATTTTCACCCACACATTCGCCGATTCAAGGAAGACATGGCTACCGAAATGTGTCTGAGTTCTCTTCGTCTcatgCAATGAATAACAATAATGGTAATCTTTACAATGTCGCTAGACATAGTGTACTTGAAGACAATCAGTCTATTGAGAACAATTTACCTGATAACATCGAAGAAAATAACGTTTACGAAGATCGAGTGCCGCCATTTACGACCGAAATGGGTCATAATTCGCCGAATCTCAATACATCTTCTGGTATTTCAAGACAGCAGCTGATAAATAGTCCTTGTCCTATCTGCGGTGACAAAATATCTGGTTTTCACTATGGTATATTTTCTTGCGAAAGTTGCAAAGGATTTTTCAAGCGAACTGTCCAGAATCACAAGAATTACGTTTGTTTACGCGGCTCTTCTTGCTTGGTCACCATTGCCACGCGAAAAAAATGCCCTGCTTGTCGATTCGATAAATGCCTGAATATGGGTATGAAACTTGAAGCCATAAGAGTTGACCGAACGCGAGGTGGTCGAAGCACGTACCCGTTTTCGTATACTTTACCCGCCAGTATTACTCCAATGCAGAATTCCAACGATTCATCTGTCAACTTGATGAAACAGGAAACAACATCTGATACGTCTCCATCATCGCCACAAATGTGCAATCGTCTTATTCCTCCATTGTTACAGgaaATAATGGAGGTCGAGCATTTGTGGCAGTACAACGAAGGAGAGACCCCAAATATTCGAACCAACGCTAATAATCCCGACTTCCTGGCGAATTTATGCAACATTGCCGACCATCGTTTATATAAAATTGTGAAATGGTGCAAATCATTGccattatttaaaaacatttctATCGATGATCAAATTTCACTTCTGATAAACGCTTGGTGCGAACTGCTACTGTTCAGTTGTTGTTACCGTTCAGTCGGATGTCCTGGAGAAATTAGAGTTAGTTTAGGGAAGTCGATTACTCTACAGAAAGCCAGAGAACTGGGATTAGCTCCGTGCATTGAGCGCATGTTGAACTTCACCGAGCATTTACGAAGACTTCGTGTGGATCGATATGAATATGTGGCGATGAAAGTTATTGTGCTTTTGTCTTCGGATTCCAGTGATTTACGAGAACCAGAAAAAGCTagagcttcgcaagaaaaagcgTTACAAGCCCTGCAACAGTATACTATTGCCCATTATCCAGATATGCCATCAAAATTTGGAGAATTGCTTTTGCGGATTCCTGATCTGCAGAGAACGTGTCAAGTTGGTAAAGAGATGTTATCAATGAAACACAAGGAAGGTGAGGGACAAAGTTTCAATCTGTTAATGGAATTATTAAGAGGTGACCATTAA
Protein Sequence
MSSIWSRAAHSVVSSGPVTVTSVNVEDVSGMKDQNITSITDAEDFSIKKEPNMLDNNVDDISDSEGELSKIDFSGVTMRSKKSRSNEVQNDQVERPMSWEGELSDSEMKQDNDNGDASVIVTETDSSQSRMENVHHEDDTKPTPLKFTTEVEQMTDSIKVNKSTSHSEIPLLVDKLLAGSCYSPVLQHRTSKTQIPPTPSPDSAIHSCYSPTQSPVTSRHLPSSGFSSPFTPSLSRNNSDASQYGGSQHSSCYSQSYSSVSVSPTQFSPTHSPIQGRHGYRNVSEFSSSHAMNNNNGNLYNVARHSVLEDNQSIENNLPDNIEENNVYEDRVPPFTTEMGHNSPNLNTSSGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNHKNYVCLRGSSCLVTIATRKKCPACRFDKCLNMGMKLEAIRVDRTRGGRSTYPFSYTLPASITPMQNSNDSSVNLMKQETTSDTSPSSPQMCNRLIPPLLQEIMEVEHLWQYNEGETPNIRTNANNPDFLANLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCYRSVGCPGEIRVSLGKSITLQKARELGLAPCIERMLNFTEHLRRLRVDRYEYVAMKVIVLLSSDSSDLREPEKARASQEKALQALQQYTIAHYPDMPSKFGELLLRIPDLQRTCQVGKEMLSMKHKEGEGQSFNLLMELLRGDH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00005508;
90% Identity
iTF_00669646;
80% Identity
iTF_00669646;