Zcuc010031.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Zeugodacus cucurbitae
Gene Symbol
Hr39
Assembly
GCA_028554725.2
Location
CM053020.1:59212762-59218667[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.03 5.7e+02 0.7 0.2 143 190 38 85 16 92 0.75
2 4 2 3.8e+04 -6.3 8.8 35 156 217 358 207 391 0.58
3 4 0.26 5.1e+03 -2.4 3.5 54 118 337 408 304 467 0.45
4 4 1.6e-96 3e-92 311.3 9.3 1 408 549 920 549 920 0.86

Sequence Information

Coding Sequence
ATGTCCTCCACAAAGGCAGAGAGCGCCGCCGGCGCCAATCCCACCGTGGCTGCCTTTGGCACAGCGCTGGCCGGTAGTGCATTCCAGCTCCCCGTGAATATGCATAGCCATGCACAGCAGCTCGCCACGAATGGCAGCAATAGTCACAGTACGAATGGCACAACTACAACaagcaccacaacaacaacacgcaacaATATATCCGTGACGAATATCAAATGCGAAATGGATGAGGGTAGTGTTGTGGCAACACTAATGCCCAACGGCAACAATATAGTGCCTGTCATAGCCACAACGGGCGCTGCTAGCTATTATAATGGTGGCAGCGGTTCAGGAGGTGTGGGTATACGCATACCAGTGACAAAAGCGGAAGATTCAGATTCCGAAGCTGAGTTGacgaatattgaaaatttaaaagtgaCGCGACGTGCGCACAACAACGCCGACAGCAGCTGTGGCACAGTGGCAGGTGGTGGTGCCGTCAGTATTGGCAACACCAATAATGGCAATCACAATAAGAATGGCCCGCGACCCATGTCTTGGGAGGGTGAACTCTCCGAAACGGAGACGACTGAAACAGAACTCATGGAGACGGAGAACTCGTTGAGTAACAGCGGTGTGACGGCGCACAATTACAGCGCTACCAGCATAGGTGTAGCGGTGATTAAGAGTGAGGCGACCACAACAACGCCGGGACACACATTGGCGCCGACGCCAACACATCCCATAAAGCCCGAGCAAATGGAGCAGATTTCCGTAGAAGTGCATGGTGGCGCGTTAGCCGGACTGGGTCCTACGATCCGCAGCGGTTTGGGCAGCAGCAGTAGCGCGGGAAGTCTTTATTCGGCCACGCATACAAAGCTCGCGCCCACACAAAGTGATCCCATCAATTTGAAGTATGAACCCGACGCTGTTGCCACGGGCTTAATGCCTGGCGGCGCTAATGTCAATTCGCCGCTTTTGACGCGCAACAAGTCTGCCACATTGCCACTGCCTGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTACACGCACAGCTCACCGTCCCAGTCGCCGTTGACCTCACGTCATGCGCCCTACACGCCGTCGCTGAGTCGTAATAATAGCGATGCATCGCATAGCTCGTGCTACTCCTACAGCTCGGAGTTTAGCCCAACACATTCACCCATCCAGGGTAGACATGCGCCACCGGCGCCAGCTCTTTACGGCAACTTCAATGGTTCGTTGCATCATTCGGTGATCTATCGACCAATCTCGGTAGCGGAGAGCGCTGCCGCTGGTGTAGCTGGTAACGGTAATACTAGCGGAAACTGCAATGCCGAAGCACAAAATCTTAGTATGGACACAAAGGTCTCGCCACTGAATATAGGTCTCGAAGGCTTGCCGTCCTCCCCAGCTGGTATTTCACGTCAGCAGCTCATCAATTCGCCATGTCCGATTTGTGGCGATAAAATTTCCGGCTTCCATTATGGTATTTTCTCGTGCGAATCCTGTAAGGGCTTCTTCAAGCGCACCGTACAGAATCGCAAGAACTATGTTTGCGTACGCGGCGGTCCATGCCCGGTTAGTATTTCGACGCGTAAGAAATGTCCCGCCTGTCGTTTTGAAAAATGCCTGCAGAAGGGCATGAAGCTCGAGGCGATACGTGAGGATCGTACACGTGGTGGACGTTCCACATACCAGTGCTCATATACGCTGCCCAACTCGATGCTGAGTCCATTAATGAGTCCGGAGCAGCAAGGCGTGGCGGCGGCGGTTGCAGCAGCTGCTGCGGCAGCTGctaatcagcaacaacaacagcacggaCGTTTGGGTGCGCAAATGATATccgcacagcagcagcaacaacagcacgcATTGAACGGCCTGGCTGCGGGACTCGGCGCTGGTCAATCCATCATCAAGTCGGAGCAATGCGACGAGAGTGGCGCGTCAGCGCGTGCAACAAACATTCCAACGCTGTTGCAGGAAATCATGGATGTTGAGCATCTGTGGCAATATAATGAAGCGGAATTGGCACGTCTCAATCAACCgatctccacatcatcatcgtctTCTTCCAATGCATCTTCGTCTTCATCTTCTACGGGGTCCGCTGCAGCCGCCAATCCACAAATGACCAACCCATTGCTAGCCAGTGCTGGTTTTGGCAATGGCGAAAACACCAATCCCGATCTGATTGCACACCTGTGCAATGTGGCCGATCATCGGCTCTACAAGATCGTGAAATGGTGCAAGAGCTTGCCGCTTTTCAAGCACATTTCGATCGACGATCAAATTTGCCTGCTAATCAATTCGTGGTGTGAGTTGTTGCTCTTCTCGTGTTGCTATCGCTCGATCGATACTCCCGGCGAAATCAAAATGTCACAAGGCAAGAAGATTAGTTTGGCCCAAGCGAAATCAAGTGGCTTACAGGCCTGCATTGAACGTATGTTGAACCTGACGGAGAATTTGAGACGTTTACGTGTCGATCGCTATGAATATGTTGCCATGAAAGTGATTGTGCTGCTGCAGTCGGACACCAGTGAATTGCATGAGCCCGTCAAGGTGCGCGAATGCCAGGAGAAGGCGCTGCAAGCTCTCCAGGCCTACACGCTTGCGCATTACCCCGATACACCGTCGAAATTCGGCGAATTGCTGCTGCGCATACCAGATCTGCAAAAGACATGTCAGCTTGGCAAGGAAATGCTCACGATTAAGTCACGTGATGGCGGTGATTTCAATTTGCTTATGGAATTGTTGCGTGGAGAGCATTGA
Protein Sequence
MSSTKAESAAGANPTVAAFGTALAGSAFQLPVNMHSHAQQLATNGSNSHSTNGTTTTSTTTTTRNNISVTNIKCEMDEGSVVATLMPNGNNIVPVIATTGAASYYNGGSGSGGVGIRIPVTKAEDSDSEAELTNIENLKVTRRAHNNADSSCGTVAGGGAVSIGNTNNGNHNKNGPRPMSWEGELSETETTETELMETENSLSNSGVTAHNYSATSIGVAVIKSEATTTTPGHTLAPTPTHPIKPEQMEQISVEVHGGALAGLGPTIRSGLGSSSSAGSLYSATHTKLAPTQSDPINLKYEPDAVATGLMPGGANVNSPLLTRNKSATLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAPPAPALYGNFNGSLHHSVIYRPISVAESAAAGVAGNGNTSGNCNAEAQNLSMDTKVSPLNIGLEGLPSSPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLMSPEQQGVAAAVAAAAAAAANQQQQQHGRLGAQMISAQQQQQQHALNGLAAGLGAGQSIIKSEQCDESGASARATNIPTLLQEIMDVEHLWQYNEAELARLNQPISTSSSSSSNASSSSSSTGSAAAANPQMTNPLLASAGFGNGENTNPDLIAHLCNVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKISLAQAKSSGLQACIERMLNLTENLRRLRVDRYEYVAMKVIVLLQSDTSELHEPVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQKTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00082980;
90% Identity
iTF_00192848;
80% Identity
iTF_01562963;