Basic Information

Insect: Zaprionus nigranus
Gene Symbol: Hr39
Assembly: GCA_018903425.1
Location: JAEIGD010000094.1:240765-244576[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 2.1e+04 -8.9 10.4 76 77 65 95 7 210 0.35

2 3 0.26 2.7e+03 -2.4 2.2 52 110 159 217 145 242 0.70

3 3 9.1e-85 9.6e-81 272.5 2.4 83 408 368 661 342 661 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	2.1e+04	-8.9	10.4	76	77	65	95	7	210	0.35
2	3	0.26	2.7e+03	-2.4	2.2	52	110	159	217	145	242	0.70
3	3	9.1e-85	9.6e-81	272.5	2.4	83	408	368	661	342	661	0.88

Sequence Information

Coding Sequence: ATGTCCAGCACGATGACCTCGACCTCGAGCAGCTCCACGACCACAAGCCGTCACAATGTGTCCGTGACGAACATCAAGTGCGAGCTGGAGGATCAGTTGCCGCAGACGCCCAATGGGAATCATCTGGTGCCTGTGATAGCCAGCTACGCGACGCATCCCCACAACAATCACAGTAGCAGCAGCAATCACATCAATCACAACAATCACAGCAGCAGCCTGCGCATACCGCTAGGCATGGGCGGGGGTGGTCAGAAGGAGGATGAGGAGTCCGACTCAGAGGCGGAGCTGGCGAATATTGAGAATCAAAAGCTGGCGCCCACGCAAAGTGATCCCATCAATCTGAAGTATGAACCCGCTGTCGGCGTCGGCGTTTGCGATCGCAGCAAATCATCAAGCGGTGGCCACCTCCCACTGTTGCCCGCCAATCCGAGTCCAGATTCTGCCATACATTCCGTCTACACGCACAGCAGCCCATCGCAATCGCCACTGACGTCACGGCACGCCCCCTACACACCCTCGCTGAGCCGGAACAACAGCGACGCATCGCACAGCAGCTGCTACAGCTATAGCTCTGAGTTCAGTCCCACCCATTCACCCATCCAGGCACGCCATGCCCCACCCGCCGGTTCAGCACTGTTTCCTGGCGGCACCGCAGCCGGCAATGGTTTGCTCTACAGGCCGCTCAATGTAGATGCTGCTGCGGCGCAGGAGCCGCAAAATCTCAGCATGGATGGAAGCGGTGTAGGTGCAGGTGCAGGTGCTGGCTCCAACCAACTGGATGCCACAGCTGCGCTGCCTGCCTCGCCAGCGGGCATCTCACGGCAACAGCTCATCAACTCACCCTGCCCCATTTGTGGTGATAAGATCAGTGGCTTCCATTACGGCATCTTCTCCTGCGAATCGTGCAAGGGCTTCTTCAAGCGCACCGTACAGAATCGCAAGAACTATGTGTGCGTACGTGGAGGTCCCTGTCAGGTGAGCATATCCACGCGCAAGAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCCATACGAGAGGATCGCACACGTGCGAGTCCCAGTCTGGGTGCATCCATTAAAACGGAGCAGACAGAGACGCTAAATCATCACGCGTCGCGTGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATTATGGATGTTGAACATCTCTGGCAATACACAGATGCGGAGCTGGCGCGCATCAATCAACCTTTGTCCTCATTTGCCAGCGGCGGCGGCGGCGGCGGCTCCACGTCGGGCTCTACGGCGAGCAATGCAACGGGTGCGGGTGGCACAGCTGGTGCCAGTGCCCAACAGATGACCAATCCACTGCTGGCCAGTGCGGGTCTCTCATCCAATGGGGAGAATGCCAATCCCGATCTGATTGCCCATCTCTGCAACGTGGCCGATCATCGACTGTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATCGATGATCAGATCTGCCTGCTAATTAATTCATGGTGCGAGCTGTTGCTCTTCTCCTGCTGCTTTCGTTCCGTTGACACGCCTGGGGAGATCAAGATGTCGCAGGGTCGAAAGATCACACTGGCACAAGCCAAAACCAATGGACTGCAGGCCTGCATTGAGCGCATGTTGAATCTGACAGATCATTTGCGACGTTTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCTGACACCACAGAGCTGCACGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGACTGCAGGCTTATACGCTGGCTCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTGTTGCGCATACCCGATCTTCAGCGCACGTGTCAGTTGGGCAAGGAAATGTTAACGATCAAGACGCGCGACGGTGCCGACTTCAATTTGCTGATGGAGCTGCTACGCGGAGAACATTGA
Protein Sequence: MSSTMTSTSSSSTTTSRHNVSVTNIKCELEDQLPQTPNGNHLVPVIASYATHPHNNHSSSSNHINHNNHSSSLRIPLGMGGGGQKEDEESDSEAELANIENQKLAPTQSDPINLKYEPAVGVGVCDRSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSALFPGGTAAGNGLLYRPLNVDAAAAQEPQNLSMDGSGVGAGAGAGSNQLDATAALPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRASPSLGASIKTEQTETLNHHASRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGGGGGSTSGSTASNATGAGGTAGASAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01559808;
90% Identity: iTF_01558327;
80% Identity: iTF_01556883;