Basic Information

Insect: Zaprionus nigranus
Gene Symbol: -
Assembly: GCA_018903425.1
Location: JAEIGD010000059.1:459422-464366[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.9e-15 1.2e-11 44.2 0.0 9 73 293 354 287 357 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.9e-15	1.2e-11	44.2	0.0	9	73	293	354	287	357	0.92

Sequence Information

Coding Sequence: ATGAGTTCGCCCGACGACAACCACGACGCGAGCAGCAGCTCAAAGTCACGTTCGAAGAGGCACTTGGAAGACTCCTCAAGCGATGATTCACAATTCACTACCAACAATAATAATCACTACGAGAATGATTCGGATCTATCCGGACAGTCGCAAACAACATCGGCCAACAATGTCCCCGTACAGAACGGCACATCTTCTAGTCGCAAGGCAAAGAAGCGCAAGGCCAAGAGGGCCAAGGAGCGACGTGGCTCGAAGGAGTCAGCTCTAGTTGGCTGGAACGGTGTGTTCCCCAATCTCTCCTCCACGCACAGCCTGGAGAGCAACTCTGATCTGGAGCAGCAGAAACGGAAACGTTTTAAGAAGCAGCACAGCTCCTCGTCGGCCTCGGCGCCAACTCCTCCTCCAGCTGCAGCTGCACCTGTCGAAGAGTCCTCGAATTCGAATGCCTCAGGTGGGGGCTCCTCAAGCAAAAGGTCCCGCAAACGTGCCATCTCAAGCAACGCAGGCTCAGGCAGTGAACAAGGCGGCAGCGGCGGTGATAAGAAACGTTTAAAGAAACTGAATCAGGATGTAAAGCAGCAACAAGTTGATGCACATCAAGAAGATGCAACTGGTAAAGGCGGCCATAATCTGCGCAAACGTGCCAAGTCGTTGTATGAACTGAACACTAATACGCCGCCGCGCATGACACGCGCTCGCAGTATTTGCGCTGCCGCTGCAGGCGACATTACCATTGACAAATCCCTTCTAAGGGCGGCCAAGAAGAGCAACAGCAACAACAATATTAACAATAATAACAAGACTAGAGCCAAGACTCCTACAAGGCGTCGCTCTGTGGCAGCAGTGAAGCTACCTGCCACCGATGTATTCTATACCCTTCCCTTTCGTTACGGTTGGAGGCGTGAACTGGTACTGCGCAGCAATCCGGGTTCGTCGCGTCATCGTAGTGATGTCATATTCATATCGCCAGATGGCAGGAAGATGCGCTCGAGGGAGGACATTTTGCCTCTTCTAAAGGCTGACGAACTGACTATAGATCATTTCTGCTTTCAACGTCAACTGCAACATGCCGGAGAACCGTACGAGACGGTTCGTCAGGCGCAGTCGGCTCCATCTCGGCGTAAGTCCTTGCTGGCAGCCAAGAAGCAACTTGACTATCATCAACAAATATACATGAAATTAAATCTCAATCAACAATCAACAGCAGCAGCAGCCTCTGCCACTACTACCGCCGTCTCCGGTAAACGTGTGCCCAAGCCGAAGGTGCCCAAAGGCGCCAGCCCGCCACCAGAGGGCTGGACATCAACCATGGCCGTCAAGGGAAACGCACGCGTTTTGGCTGCAAGCAATGGTAACTCTGGCAGCGGGTCCGGCTCTAGTACAGGCAATGCAACACGTGGCAAACTGGGAGAGAACAAGATCTGTGTGTATTGCCTGCAGCCAATTAAGGAGCTCAATTCGGCATACACGGTGGGAGCACCGAACATCAATTATATATGCAAGCGCTGTGTTAAGCCTGGCAGCAAAGCTGTCGCTAAGGCAGGAGGATTACCCACGGCACGTGGACATGCCAATGGCATCAAGAAACAGGACAAGAAGGAACCGATTGATGAGAATCTTGGCGCAAATGGCGCCAAACCATCACCAGCAGCTGCAGCTGTTTATGGCTACGAGACAACAAATGCAGATGCTGAAAAGAATGGGGTCAATGGCAGCGGAAGTGGTATCATGCTTGAAATCGGTGGCGAGATAGAGCTACCCGGTGCCCTGCCGCCAGATCAGTTATTAAGCGATGATAATACCAATTGGGCTGGCAACAAGATCACTGCCAAGCCGCAGGAGGTGGTTGTCATAAATGGACGCAAGGCGCTGGCAATTGCTGGCGAGCCACCGCGTCCGCGTTTACAAGTTGCGCCTCGCGAGCCCGACTTGGAGGCCTATGATAAACACTATCATCCCAAGCGCAACTCAACAGCCAAGGAGAAGCGTCAGAGTTTCATCGAGTGCATTGCCAGTGGCAATCAGAGCTGCCAGGTTATGCTGGCCGTGATGAAGACACTGGATCTACATGATCGTGTACGCATGTCCAATGTGTGCAAGACCTGGGCCATGATTGCCCGCGATCGCAGTGTGTGGCGCTCATTGAAGCTGCGTGACACGCGCATCACCAACTGGCTGTTCTGTCTGCGTGACATGGCGCGCAACCGCACTCGCGAACTGGACATGATGGGCGTGAAAATGGACTCGCCCAAGCTGCGCATGGAGGGTGATCTCCGTGTGCTGAAGTCGTTGCGCATCCTGCGTACCGACGCTTGCGAGGCTGAGTTCATACAGGCGGTGATAAAGCGTATACCACGCCTGCTCGAGCTGCGCGCCACTTGCACCAGTCGTGCCCTTAATTTGACCAACATTGATAAGATGGTGGATCTGCGCGTATTGCGCATACGCATGACCGAGCCGAAGGCAGGCATTGTGTCGCTGCAACCGTTGCAGAAGTTGCAACACTTGCGTGAGTTGAGTCTGCGCGGCATCAACAACATGGCACAGCTGGAGCTGACGCAGCTGAAGGAGTTGACCAATCTGGAGACGCTGGTGTTGGGCTCATCACGTGGCATGAAGATTGCTGTGCTGGGGCAGCATGTGTTGCCCAATCTGAAGAAGTTGCTTCACCTGCGCATCGAGAATCAAAACAATAATCGCTCCTTCAGCATCTCGGAACTGATGGATGGCCTTGCTGCCGGCGGTGGCAGCAGTGTGAAGCGTCTGGAGCTGGTCAATGTCAATGTGGATGCTGCATTCAGTCGCCAGTTGGCCGATTGTAAATCGGTTCACGAACTGCTGCTAATGCCGAACTTCCACAACAACACCGCATACATGATGCACTACGTCATCCAGGCCATCAATGAGAACTGCGAACAGCTCAACGTATTCCGCCTGGGCTTGACCTACGAACTGTTGCGCGTCACTCGAGCACTGGCCATGAACAATGAGAAGGACTGTGTACCAGTGGCACTGCCTATACCCGGTGTGCCCGAGAATGATCTGCTGAATGAGTCGGACGAGCCCATTGCCTATTTGCCAGTTGATCGCCTGGAGTCTATACTGCATCACATGATGCCACAGGCCTGGCTGACTGTCGCCAAGGTTTCACAAAGCGAAACATGCAATCTGCAATTTCCAGCTTCGCCCAAGTGTGATCCCAATGGCTCTCTACACACTTAG
Protein Sequence: MSSPDDNHDASSSSKSRSKRHLEDSSSDDSQFTTNNNNHYENDSDLSGQSQTTSANNVPVQNGTSSSRKAKKRKAKRAKERRGSKESALVGWNGVFPNLSSTHSLESNSDLEQQKRKRFKKQHSSSSASAPTPPPAAAAPVEESSNSNASGGGSSSKRSRKRAISSNAGSGSEQGGSGGDKKRLKKLNQDVKQQQVDAHQEDATGKGGHNLRKRAKSLYELNTNTPPRMTRARSICAAAAGDITIDKSLLRAAKKSNSNNNINNNNKTRAKTPTRRRSVAAVKLPATDVFYTLPFRYGWRRELVLRSNPGSSRHRSDVIFISPDGRKMRSREDILPLLKADELTIDHFCFQRQLQHAGEPYETVRQAQSAPSRRKSLLAAKKQLDYHQQIYMKLNLNQQSTAAAASATTTAVSGKRVPKPKVPKGASPPPEGWTSTMAVKGNARVLAASNGNSGSGSGSSTGNATRGKLGENKICVYCLQPIKELNSAYTVGAPNINYICKRCVKPGSKAVAKAGGLPTARGHANGIKKQDKKEPIDENLGANGAKPSPAAAAVYGYETTNADAEKNGVNGSGSGIMLEIGGEIELPGALPPDQLLSDDNTNWAGNKITAKPQEVVVINGRKALAIAGEPPRPRLQVAPREPDLEAYDKHYHPKRNSTAKEKRQSFIECIASGNQSCQVMLAVMKTLDLHDRVRMSNVCKTWAMIARDRSVWRSLKLRDTRITNWLFCLRDMARNRTRELDMMGVKMDSPKLRMEGDLRVLKSLRILRTDACEAEFIQAVIKRIPRLLELRATCTSRALNLTNIDKMVDLRVLRIRMTEPKAGIVSLQPLQKLQHLRELSLRGINNMAQLELTQLKELTNLETLVLGSSRGMKIAVLGQHVLPNLKKLLHLRIENQNNNRSFSISELMDGLAAGGGSSVKRLELVNVNVDAAFSRQLADCKSVHELLLMPNFHNNTAYMMHYVIQAINENCEQLNVFRLGLTYELLRVTRALAMNNEKDCVPVALPIPGVPENDLLNESDEPIAYLPVDRLESILHHMMPQAWLTVAKVSQSETCNLQFPASPKCDPNGSLHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01548849;
90% Identity: -
80% Identity: -