Basic Information

Insect: Zaprionus africanus
Gene Symbol: -
Assembly: GCA_018151435.1
Location: JAECXB010000076.1:10343160-10348104[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.9e-15 1.2e-11 43.8 0.0 9 73 302 363 295 366 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.9e-15	1.2e-11	43.8	0.0	9	73	302	363	295	366	0.89

Sequence Information

Coding Sequence: ATGAGTTCGCCCGACGACAACCACGACGCGAGCAATAGCTCAAAGTCAGGTTCGAAAAGGCACTTGGAAGACTCTTCAAGCGATGATTCACAATTCGCTACTAACAATAATAATCACTATGAGAATGATTCGGATCTATCCGGACAATCGCAAACAACATCGGCCAACAATGTCGTTCAGAACGGCACATCTTCTAGTCGCAAGGCAAAGAAGCGCAAGGCCAAGAGGGCCAAGGAGCGACGTGGCTCAAAGGAGTCAGCTCTAGTTGGCTGGAACGGTGCGTTCCCCAATCTCTCCTCGACGCACAGCCTGGAGAGCAACTCTGATCTGGAGCAGCAGAAACGGAAACGTTTAAAGAAGCAGCACAGCTCCTCGTCGGCGTCGGGGCCACCTCCTACTCCTCCTCCAGCTGCAGCTGCTGCAACTGCCGAAGAGTCCTCGAATTCCAATGCCTCAGGCGGGGGCTCCTCAAGCAAAAGCTCCCGTAAACGTGCCATCTCAAGCAATGCAGGCTCAGGCAGCGAACAAGGCGGCGGCGATAAGAAGCGTTTAAAAAATATGAATCAGGATGCAAAGCAACAAGTTGATGAAAATCAAGAAGAGGCACCTGGGAAAGGTGGCCATAATCTGCGCACACGCTCCAAGTCTTTGTATGAACTGAACACTGAGTCGCCGCCGCGCCGTATGACACGCGCTCGCAGTATTTGCGCTGCTGCTGCAGCAGACGACATTGTCATTGACAAATCCCTTCTAAGGTCCGCCAAGAAGGAGGCAAAGACACCTCTACGCAGTAGCAACAGCAACAACAACCTTAACGATAATAATAAGACTGGAGCCAAGACCCCCACAAGGCGTCGCTCCGGGGCAGCAGTGAAGCTACCTGCCACTGATGAATTTTATACCCTACCTTTTCGTTACGGTTGGAGGCGTGAATTGGTGCTCCGCAGCAATCCTGGTTCGTCGCGTCATCGCGGTGATGTCGTATTCATAGCGCCAGATGGAAGGAAGATGCGCTCGCGAGAGGACATTCTGTTTCTGTTGCACGGTACCGAACTGACCATAGATCATTTCTGTTTCCAACGTCAACTGCAACATGCCGGAGAACCGTACGAGACAGTTCGCCAGGCGCAGTCGGCTCCATCTCGTCGTAAGTCCTTGCTCGCAGCCAAGAAGCAGCAGCTCGAACTACATCATCAAATATACATGAAGTTAAATCCGAATTTCAATCAACAATCAACAGCAGCAGCAGTCTCTGCCACCACAACGCCGGTCTCTGGAAAACGTGTGCCCAAACCGAAAGTGCCCAAAGGCGCCAGCCCGCCACCAGAAGGCTGGACATCAACCATGGCCGTAAAAGGAAACGCGCGCGTCCTGGCTGCAAGTAATGGTAACTCTGGCAGTGGTTCCGGCTCAAGTACAGGCAATGCGGCACGCGGCAAACGTGGCAACCACATGAAGCAATCTCCTAAGATTGCAGCTGTTGCTGCATCGCAGGCAAAGACCCAGTCGCAGCCGCAGCAACCACAGGCTCAGCTAGTGGGAGAGAACAAGATCTGTGTGTATTGCTTGCAGCCAATTAAGGAGAAGCTTAATGCGTCCCACTCGGTGGGAGCACCCAACAATTATACATGCAAGCGCTGTGCTAAGCTTGGCAGCAAAGCTGTCGCGCTAGCTAAGGCAGGAGGATTACCCACGGCACGTGGAAACGCCAATGGCATTAAGAAACAGGACAAGGAGAAAGAGCCGATTGATGAGAATATAAACGCCAATGCAAACGGCGTCAAGCAATCACCAGCAGCTGGAGCTGTTGATGGTGACGAGACAACAAAGGAAGCAAATGCAGATGCTGATGCTGATCAGAATGGGGGCGATGGCAGCGGAAGCGGTGTCATGCTTGAAATTGGTGGCGAGATAGAGCTACCCGGTGCTCTGCCACCAGATCAGCTCTTAAGCGATGATAATTCCAATCGGTCTGGTAACAAGATCACTGCCAAGCCACAAGAGGTGGTTGTCATTAATGGACGCAAGGCGCTGGCAATTGCGGGCGAGCCACCGCGTCCGCGTTTACAAGTTGCACCTCGCGAGCCAGACTTAGAAGCATATGAGAAACATTATCATCCCAAGCGCAACTCAACGGCCAAGGAGAAGCGTCAGAGCTTCATCGAGTGCATTGCCAGCGGCAATCAGAGTTGCCAGGTAATGCTGGCCGTAATGAAGACACTGGATCTACATGATCGTGTACGCATGTCCAAAGTCTGCAAGACCTGGGCCATGATTGCCCGCGATCGCAGTGTGTGGCGCACTTTGAAGCTGCGTGACACGCGCATCACCAACTGGCTGTTCTGTCTGCGTGACATGGCGCGCAATCGCACTCGCGAACTGGACATGATGGGCGTGAAAATGGACACACCCAAGCTGCGCATGGAGGGTGATCTGCGTGTGCTTAAGTCGTTGCGCATCCTGCGTACTGATGCTTGCGAGGCTGAGTTCATACAGGCGGTGATAAAGCGTATACCACGCCTGCTCGAGCTGCGCACCACCTGCACCAGTCGTGCCCTTAATTTGGCCAACATTGAGAAGATGGTCGATCTGCGCGTGTTGCGCATACGCATGACCGAGCCGAAGGCAGGCATTGTGTCGTTGCAACCGTTGCAGAAGTTGCAACACTTGCGTGAGCTGAGTCTGCGCGGCATCAACAACATGGCACAGCTGGAGCTGACGCAGCTGCAGGAGTTGACCAATCTAGAGACATTGGTGTTGGGCTCATCGCGTGGCATGAAGATTGCTGTGCTGGGACAGCAAGTGTTGCCCAATCTGAAGAAGTTGCTTCATCTGCGCATCGAGAATCAAAACAATAATCGCTCCTTCAGCATCTCGGAACTGATGGATGGACTCGCCGCCGGCGGTGGCAGCAGTGTGAAGCGTCTGGAGCTGGTTAATGTCAATGTGGATGCTGCATTTAGTCGTCAGTTGGCCGATTGTAAATCGGTTCAGGAACTGCTGCTAATGCCAAACTTCCACAATAACACCGCATACATGATGCACTACGTCATCCAGGCCATTAATGAGAACTGCGAACAGCTGAACGTGTTCCGCCTGGGCTTGACCTATGAGCTGTTGCGCGTCACTCGCGCACTGGCCATGAACAATGAGAAGGACTGCGTACCAGTGGCACTGCCCATACCCGGCGTGCCCGAGAATGATCTGCTGAATGAGTCGGACGAGCCGATTGCCTATTTGCCAGTTGACCGGCTTGAGTCTATACTGCATCACATGATGCCACAGGCCTGGCTGACTGTCGCCAAGGTTTCACAGAGCGAGACATGCAATCTTCAATTCCCAGCATCGCCGAAGTCCGATCCCAATGGCTCTCTACACACTTAG
Protein Sequence: MSSPDDNHDASNSSKSGSKRHLEDSSSDDSQFATNNNNHYENDSDLSGQSQTTSANNVVQNGTSSSRKAKKRKAKRAKERRGSKESALVGWNGAFPNLSSTHSLESNSDLEQQKRKRLKKQHSSSSASGPPPTPPPAAAAATAEESSNSNASGGGSSSKSSRKRAISSNAGSGSEQGGGDKKRLKNMNQDAKQQVDENQEEAPGKGGHNLRTRSKSLYELNTESPPRRMTRARSICAAAAADDIVIDKSLLRSAKKEAKTPLRSSNSNNNLNDNNKTGAKTPTRRRSGAAVKLPATDEFYTLPFRYGWRRELVLRSNPGSSRHRGDVVFIAPDGRKMRSREDILFLLHGTELTIDHFCFQRQLQHAGEPYETVRQAQSAPSRRKSLLAAKKQQLELHHQIYMKLNPNFNQQSTAAAVSATTTPVSGKRVPKPKVPKGASPPPEGWTSTMAVKGNARVLAASNGNSGSGSGSSTGNAARGKRGNHMKQSPKIAAVAASQAKTQSQPQQPQAQLVGENKICVYCLQPIKEKLNASHSVGAPNNYTCKRCAKLGSKAVALAKAGGLPTARGNANGIKKQDKEKEPIDENINANANGVKQSPAAGAVDGDETTKEANADADADQNGGDGSGSGVMLEIGGEIELPGALPPDQLLSDDNSNRSGNKITAKPQEVVVINGRKALAIAGEPPRPRLQVAPREPDLEAYEKHYHPKRNSTAKEKRQSFIECIASGNQSCQVMLAVMKTLDLHDRVRMSKVCKTWAMIARDRSVWRTLKLRDTRITNWLFCLRDMARNRTRELDMMGVKMDTPKLRMEGDLRVLKSLRILRTDACEAEFIQAVIKRIPRLLELRTTCTSRALNLANIEKMVDLRVLRIRMTEPKAGIVSLQPLQKLQHLRELSLRGINNMAQLELTQLQELTNLETLVLGSSRGMKIAVLGQQVLPNLKKLLHLRIENQNNNRSFSISELMDGLAAGGGSSVKRLELVNVNVDAAFSRQLADCKSVQELLLMPNFHNNTAYMMHYVIQAINENCEQLNVFRLGLTYELLRVTRALAMNNEKDCVPVALPIPGVPENDLLNESDEPIAYLPVDRLESILHHMMPQAWLTVAKVSQSETCNLQFPASPKSDPNGSLHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01551725; iTF_01557555; iTF_01550273; iTF_01553959; iTF_01552450; iTF_01559754; iTF_01556827;
90% Identity: iTF_01557555;
80% Identity: -