Zkol004865.1
Basic Information
- Insect
- Zaprionus kolodkinae
- Gene Symbol
- Hr39
- Assembly
- GCA_018901885.1
- Location
- JAEIFM010000247.1:772336-775777[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.058 4.8e+02 -0.2 0.6 59 133 22 98 5 126 0.55 2 4 0.065 5.3e+02 -0.4 7.7 52 176 314 433 296 440 0.81 3 4 1.3e-08 0.0001 21.7 0.0 1 23 503 525 503 533 0.92 4 4 1.7e-84 1.4e-80 271.6 4.6 82 408 615 904 589 904 0.86
Sequence Information
- Coding Sequence
- ATGCCCAACATGTCCAGCATTAAGACGGAGCAGGGCGTGTCTCCCAGTGGCTCCATCGGCAGCAGTTACCAGTTGCCGGTGAACATGTCCACAACGTCGAGCAGCTCCACGACCCGCCACAATGTGTCCGTGACGAACATCAAATGCGAGCTGGAGGATCAATTGCCGCAGACACCGAACGGGAATGGGAATGGGAATCATCTGGTGCCCGTGATAGCCAGCTATGCGACGAGCCACAACAATCACAGCAGCAATCACATCAATCACAACAATCACAACAATCACAGCAGCAGCAGCAGCCTGCGTATTCCACTGGGCGGCATCCATGGCGGACTGGAGCAGCGTGAGGATGCCGATGAGGAGTCCGATTCGGATGCAGAGTTGGCGAATATTGAGAATCAAAAGGTGCGACGACGCGGCAACGATAAGAACGGACCGCGTCCCATGTCCTGGGAGGGGGAACTGAGTGAACCCGAAGGGGGCAATCAGGAGCAGGGCGAGGAGCTGATGGACACGGAGACGGTGATCAAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACTGAAACTGGCGCCCACGCAAAGTGATCCCATTAATCTGAAGTATGAGCCTGCTGCCAGCATTGTGGGTCAACCCTCAACCCTTTGCGATCGCAGCAAATCCTCCAGTGGCAGCCATTTACCGTTGCTGCCCGCCAATCCGAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGTCCGTCACAGTCGCCGTTGACATCACGCCACGCCCCCTACACGCCCTCGCTGAGTCGCAACAACAGCGATGCATCGCATAGCAGCTGCTACAGCTACAGCTCCGAATTCAGTCCCACCCACTCGCCCATCCAGGCACGACATGCACCGCCAGCCGGGTCTACGCTGTTCCCGGGCAGCGCAACCAACGGATCTGCTTCACTGCATCATAGTGTGCTCTACAGGCCGCTCAATGTGGAAGCCACAACGCAGGAGGCACAAAATCTCAGCATGGATGCGAGTGCAGGTGGTTCCACACTGGATGCAAGTGCCACACTGCCAGCCTCCCCGGCAGGCATCTCACGGCAACAGCTCATCAATTCACCCTGCCCCATTTGCGGTGATAAGATCAGTGGCTTCCATTATGGCATCTTCTCCTGCGAATCGTGCAAGGGCTTCTTCAAGCGCACCGTACAGAATCGCAAGAATTATGTGTGTGTGCGCGGTGGTCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCCGCCTGCCGCTTTGAGAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATACGGGAGGATCGCACACGTGGCGGTCGTTCAACCTATCAATGCTCCTACACGTTGCCCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGGATCGCATTCCTTGCCAGCTAGTCCCAGTCTGGGCGCATCCATTAAAACGGAACAAACGGAGCCGCTCAATCATCATCATGCAACGCGTGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCAGAACTGGCGCGCATCAATCAACCCTTGTCCTCCTTCGCCACCGGCGGCACCTCGTCCACGGGCTCCACGACAGGCTCCAGTGGCGGTGCAGCAGGTACAGCTGCAGCCAGTGCCCAACAGATGACCAATCCACTGCTGGCCAGTGCAGGTCTCTCATCCAATGGCGAGAATGCCAATCCCGATTTGATTGCCCATCTCTGCAATGTCGCCGATCATCGACTGTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATCGACGATCAGATCTGCCTGCTCATCAACTCATGGTGCGAATTGCTGCTCTTCTCCTGCTGTTTTCGTTCCATCGATACGCCCGGCGAAATTAAGATGTCGCAGGGTCGCAAGATTACGCTGGCACAGGCCAAAACCAATGGACTGCAGGCCTGCATTGAGCGCATGTTGAATCTGACCGATCATTTGCGACGTTTACGCGTTGATCGCTATGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCGGACACCACAGAGCTGCACGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGCACTGCAGGCCTATACGCTGGCACATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTGTTGCGCATACCCGATCTGCAGCGCACATGTCAGTTGGGCAAGGAAATGCTGACGATCAAGACGCGCGATGGGGCCGACTTCAATTTGCTAATGGAGCTGCTACGCGGAGAACATTGA
- Protein Sequence
- MPNMSSIKTEQGVSPSGSIGSSYQLPVNMSTTSSSSTTRHNVSVTNIKCELEDQLPQTPNGNGNGNHLVPVIASYATSHNNHSSNHINHNNHNNHSSSSSLRIPLGGIHGGLEQREDADEESDSDAELANIENQKVRRRGNDKNGPRPMSWEGELSEPEGGNQEQGEELMDTETVIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKLAPTQSDPINLKYEPAASIVGQPSTLCDRSKSSSGSHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSTLFPGSATNGSASLHHSVLYRPLNVEATTQEAQNLSMDASAGGSTLDASATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSHSLPASPSLGASIKTEQTEPLNHHHATRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGTSSTGSTTGSSGGAAGTAAASAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01551029;
- 90% Identity
- iTF_01559065;
- 80% Identity
- iTF_01554752;