Basic Information

Insect: Xestia xanthographa
Gene Symbol: IKZF1
Assembly: GCA_905147715.1
Location: LR990655.1:20157580-20167690[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.6 7.2e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 20 0.099 20 7.9 4.1 1 23 84 107 84 107 0.97

3 20 5.8 1.1e+03 2.3 4.0 1 23 197 219 197 219 0.96

4 20 0.002 0.39 13.2 1.0 2 23 225 246 224 246 0.97

5 20 2.4 4.7e+02 3.5 1.4 1 23 252 274 252 275 0.94

6 20 0.24 47 6.7 3.4 2 22 508 528 507 528 0.95

7 20 0.099 20 7.9 2.6 1 23 625 647 625 647 0.95

8 20 0.68 1.4e+02 5.2 0.3 2 23 781 802 780 802 0.96

9 20 0.0013 0.26 13.8 0.5 2 23 882 903 881 903 0.96

10 20 0.25 50 6.6 0.6 1 23 911 933 911 933 0.97

11 20 5.7 1.1e+03 2.3 2.6 1 23 969 991 969 991 0.93

12 20 0.00028 0.055 15.9 4.0 1 23 999 1021 999 1021 0.99

13 20 0.26 51 6.6 1.8 1 23 1102 1124 1102 1124 0.98

14 20 0.55 1.1e+02 5.5 0.5 1 19 1208 1226 1208 1230 0.94

15 20 0.0022 0.44 13.1 0.8 1 23 1297 1319 1297 1319 0.96

16 20 0.032 6.3 9.4 1.1 1 23 1325 1347 1325 1347 0.95

17 20 0.0077 1.5 11.4 2.6 1 23 1436 1458 1436 1458 0.97

18 20 0.00019 0.038 16.4 1.4 1 23 1464 1486 1464 1486 0.99

19 20 0.96 1.9e+02 4.8 2.7 1 23 1578 1600 1578 1600 0.96

20 20 0.011 2.2 10.8 5.6 1 23 1611 1633 1611 1633 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.6	7.2e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	20	0.099	20	7.9	4.1	1	23	84	107	84	107	0.97
3	20	5.8	1.1e+03	2.3	4.0	1	23	197	219	197	219	0.96
4	20	0.002	0.39	13.2	1.0	2	23	225	246	224	246	0.97
5	20	2.4	4.7e+02	3.5	1.4	1	23	252	274	252	275	0.94
6	20	0.24	47	6.7	3.4	2	22	508	528	507	528	0.95
7	20	0.099	20	7.9	2.6	1	23	625	647	625	647	0.95
8	20	0.68	1.4e+02	5.2	0.3	2	23	781	802	780	802	0.96
9	20	0.0013	0.26	13.8	0.5	2	23	882	903	881	903	0.96
10	20	0.25	50	6.6	0.6	1	23	911	933	911	933	0.97
11	20	5.7	1.1e+03	2.3	2.6	1	23	969	991	969	991	0.93
12	20	0.00028	0.055	15.9	4.0	1	23	999	1021	999	1021	0.99
13	20	0.26	51	6.6	1.8	1	23	1102	1124	1102	1124	0.98
14	20	0.55	1.1e+02	5.5	0.5	1	19	1208	1226	1208	1230	0.94
15	20	0.0022	0.44	13.1	0.8	1	23	1297	1319	1297	1319	0.96
16	20	0.032	6.3	9.4	1.1	1	23	1325	1347	1325	1347	0.95
17	20	0.0077	1.5	11.4	2.6	1	23	1436	1458	1436	1458	0.97
18	20	0.00019	0.038	16.4	1.4	1	23	1464	1486	1464	1486	0.99
19	20	0.96	1.9e+02	4.8	2.7	1	23	1578	1600	1578	1600	0.96
20	20	0.011	2.2	10.8	5.6	1	23	1611	1633	1611	1633	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGAGCGCACAAGTCGGCGAGGTCGCGACTGTCGTGCGCCACCTTGAAGGCCGAGTCTGCGGCGACGTGTCTTCGGAGGCCTCCTCCGATGCCGCCGAGGATTTTGAATTACCAGAGTGCAAGATAAAGAGGAATTATAATTGCACCAAATGCACATTCTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGCGACGCACACTTCGTTAGACTCAAGATTTACGATTGTCCACACTGTGTTTACGCTTCGAGACATCATCAGAAACTTATAAGACACGTCAAAATGGTTCACTCAGGATCGAAGGCAAATGCTGCGGCCGGTAAAGTGGGTACTTTACCGGCCGCAGAGCTATCATCTCCCCCCAACGACAACATGGAGCCAGCAGAGCGCATTGAAGACATGCTAGAGGAAGTCGAAGACTGCGAGGATATGATGATGGAAGTAGATGAGGACTCCATGGACCAACCTGATGATATCGACGGCGACTGCGATAGAAATGTTGACTACACTTCGCCGTCTTATCGGAGGGCACATCTGTCTAAAGCTAAGGGCAAATTCTTCTCATGCGATAAGTGTAACTATGTCACCCACATAAGAGCTAGATTCACAAAGCATGTAAAGTATCATTCCATGCCTATGATCAAGTGTACAATGTGCGATTTCCGAACACCGTACAAGTGGAATTTGGACCGTCACATGAAGAACCACGGTGGAAGTGGAAGTTTCAATTGTTCGATGTGCAACTTCACGGCGGACATCAAGCAGAGTCTGACGGTGCACGAAATGAATCATCACATTCCGCCAGCGGGCCAATCGTTGTCGAGTCGGCGCCGCAACCGGGTGGGCGCCAGCGACACGGTGTCCGCCGAGTTCGACGCAGCGAGCGCGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCACGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATACGCAGACAGAGAACTAGTCAGTTGCAAAAGTGATTCCAATGACGGTACAGCGTCAGATGCAATCACCCGAAAGGAGAACTCGCAAGATGGGTACAACCAGCTTTCACCGACCAACAGCACAGATGAGAGGCTACAAAAACAAAGCAGAAAGATTCCACGACCAATACCACAACTGATACCGCTAAACTCTTCAACTCCCAACCAAAAACAAACAGGCTCAGGTGAACCGCCACAGAAAAAGTTCAAGGAATCTTTACCCATAGACATTGACGATATATCTGCTGAGAATACTCTTTTCCCAACAAATACTTCATCAAAAGAAACTGCAGGTCGAAAGAAAAATGAATCATTTTTCGACAGATTAAAAGAAAGACTGCTAACAGAAACAGGCGAAGAAGGTTCACTCATATGCAAGATCTGTGGATTTGAAAGTAAATGCCTATCAGAACATTCTGTCCACGAGAAAAATTGTTCACCACAAACGAACCGGATCAACGCAAACACGTCGGTCAAAAGTTTAAGTTCCACTCGATGTCAGAATTGCAGACACAGATGTAAATCTAGCGCAGACTTGTACATTCACATGCAAACTTGCGGAAAGACCGAGAACATCGACGATCACACTATcaaaaatgaaaatagtaaTGATGGAATCATTCCGATCCATGAAAAAGAGACTGAACCGCACCCAATGGAAAACGTCGTTTTTGTTTGGAACAATATTAATCATGACCCTAACAAGTTTGAAATACCTCTAGACATAAACATAAATGATGATTCCACACTACCAGAAATACATCGAAGTTTTGATCCTGCAGAGATTGTTGATGACAATGAAAGCATAAATTTGTCGCCGAGTCAAGCTATTGGAAGGAAGGTATTTAAATGTCCACATTGTCCATTTTTCTCCACAACAGCGTCCAGATTTCACGTTCATATCGTGGGTCACTTAAACAAAAAACCATTTGAGTGTTCCCTCTGCAAATATAAATCTAATTGGAGATGGGATATAACAAAACACATTAAATTGAAATCCGCGAGAGATCCCGAACATAACGAAGCAAAAGTACTTATGACTGATGAAACAGGGAGAAGAAACTATAGCAAATACAACAAATTCTTAGCAATGCCGGTTTTAAATGAATATGGTGAAAATGAGTTCACTTACCTGGATTCTAATACTGCTGTTGATAGCACGATGGAAATGGATGAATCATTTAATGATATATCAGACGTACAATTTGAAATGCAACCGCTTAACTTACAGACTCAACACATTGAAGATAATTACAACTTTATTGATATTAGAGGTCTGAATGATATGAAGAAGCCCAAGAAAACATTATGGAaatgtaaaaaatgtaattacaAaGATCCTTCaaaagaagcccttcttgagcACGTTCGTGAACACTCCAGATCGGATGGCTTCCATGACGAACACAACAAAACACCTgttaaaaaacctgaaaataatACTCCCGATCCAGCAGATCTGGCGTATCGTTGTGGGCATTGTAATCAATTGTCTAATTGGAAGCATGTCATCCAGCGCCATTGCCGATTAAAACACGATGGAATAATCAAAGTGATAACTACAGTCAAACCAAAACCTGACCCACCCATGAACATCAATGAGATTAACATCGATACTTGCAACAAGTGCCCCTACAGAACGAGTGACAAGAAACTACTCATCGCGCATTTACAACAGCATCAGCCCTCGGCGAACTCTATATTCAAGTGCTACTTCTGCCAATTCTTTGTAAAGGATGAGCCAGAATTGATCCAACATCTACTGCTGCACGGCATCACTGACCCAGAAGATTACATCGCTAAAGCAAGCGGAACTAAATCCCCAGGACCAGAACCCCCACCACCTGTTCCTACGCCACTAAACTCCACCAAGCGTCACAAATGCATAGAATGCCCATACGAAACAAATAGCAAGTCACAATTCATGTACCACGAACAGTTCCATCGACTTCCGGCCGACACGCCTTACAAATGTCCAGAATGCAACTACAGCGTATCTAAGAGACACCTGCTGCACCAGCATTTGCGAGTACACGGAATAGCAACCAAAAGAACTGAAACTGAGGCCGAATTAGAAGCATCAACATCAGCACAAAACAAATTTGACTTCCAAATGAATCTTGATGAAATACCATTTGTTTGGGTTTCGGCAAAGAATGAGTTCCATAAAATGTACAAGTGCCGATATTGTTCATACGTTAACGCTATCAAGTGCAAAATTCCAAATCACGAAAAAATTCATTGCATCGTATTCGAAAACAATGATACAACCATTTACAAGTGTTTGGAATGCAAATTCACATGTGATAACGCCGGCCGGCTAGCAGAGCATTCCAAATCACACGGGGAAATATATGGTCGCATTTATTGTCCTGTGGAATACGATGTACCCGATGAAGAACAAATCACTAAATTGAGGAAAGTTATAGAAATTGAAAAGTCAGCAAATCCAGAAAGTTTCTCCAGAGATGAAGGCACTACGCACGAAAATAGAGAgctaaaaatattgtacttttGTCAAAAATGCCCTGCAAGATTTTTTGAAGAGGGCGAAATTGACACTCATGAAAAATGCCATGATGTAACTTTGCCTCATAAATGTAAAAGTTGTGACTTTTCAGTTACCGAAGAAAGTGAATTAGCGGCACATGATACCGTGCACACGGATGAATATCACACAAAAACGAAGATGCTTAAATTTGTTCACCACTCACATCCTTCGCACAGACAACCCGTGCTAGAGCTTACTCACTGTCCCAACACTTCCGATATTACGTGGATAGCCACTGGACCAAGTAAAGTTGAATATATCGAAAGTCCtatgaaaaaaacaaatgataCAAAACACGCGCCAAAACAATATAGCTGCAAACAATGTCCAGCGAAATTTTTCAAAAGTTCCGCGCTTACATATCACATGGGTCTACACGGAGGTGATGGCGAGCATAAGTGCAAGAAGTGTAACTACGCCGTGAAGAACATTGGGAATCTAGGCAAACACGAACTTCTTCACGACAATGAGAACAAGACAAATTGCGACTATGAATCCGGTGAAGATATGGATTACAAAAATATCCCACTGTCGGGCACAGATTTGTTCCAGAGGAAGACTGAAGCTCAGAAAAGAGTTTTAAATGATAAAGATAAGTTAGTTAAACCAAATGACCATTTTCCGCCTGTCTTACAAGCCGATCCCCAATTCGGTTATTTAATGCATGGGAATCCAGAATTCATATATCCCACATACCTGAAAAATGGACGCCAAAAAGAAAAGCGATACAAATGCCACAAGTGCCCCTCAGCCTTTGAGAAAAGAGAGCaatataaaattcatttatCATTACACGGCTCCAAGCAAAGATATAAATGTGAGTTATGTGATTATTCAGTAAAATATTACGCTAATTACGTTCAACATATGCGAAAACATCAAATGAACGATGAAGCTCAagctgaaagaaagaaagataataATGATTTTACAGAATCTGAACATCAAGAAGACGTTAAGCAAGAGGACAGTAGTGATAATATAAAACTCGCAATAAAAACTATGCCAAAAGGAACTGCCAAGAGCGACTTCCAACAATTCTCAATTAGCGACCAGCAAACCCTCAGACTGCTACAGAGGAGACGGTCTATGAATAATTCTGGAAAGGACCCTAACGCTTCAGAAACTTCGCCGATCAAAGAACGTAAAATGCACATGTGTCTACTGTGTCCGTACACCAACCAACGTCAAGATTCTTTGAGTAATCATTACAGAAGACACGGTGACACTGATGTGATGAACGCCGGAAGTCATAAATGTTCCCATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTTCGGGAACATCTGAAGACACACTTCAATTACCACAAAATTCTTATTCCCGAATGTTTCGTGGCTAATGAAGCTGTTAGTTTTACAATAACCAAGTTGGATGAAGATAGTGAATCAGTTGATCTCAAATTAGACCTGCAGAACAAGAGTTTTGCATGTAATGATGAAAAGATATTTGTGAAAATTAAAACGGGAGAGCTATTGGTCGAATAA
Protein Sequence: MLQQMSSPPSAQVGEVATVVRHLEGRVCGDVSSEASSDAAEDFELPECKIKRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHSGSKANAAAGKVGTLPAAELSSPPNDNMEPAERIEDMLEEVEDCEDMMMEVDEDSMDQPDDIDGDCDRNVDYTSPSYRRAHLSKAKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFNCSMCNFTADIKQSLTVHEMNHHIPPAGQSLSSRRRNRVGASDTVSAEFDAASALLPKEEEGSGDSRSSHSVSDMGLQYADRELVSCKSDSNDGTASDAITRKENSQDGYNQLSPTNSTDERLQKQSRKIPRPIPQLIPLNSSTPNQKQTGSGEPPQKKFKESLPIDIDDISAENTLFPTNTSSKETAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSVKSLSSTRCQNCRHRCKSSADLYIHMQTCGKTENIDDHTIKNENSNDGIIPIHEKETEPHPMENVVFVWNNINHDPNKFEIPLDININDDSTLPEIHRSFDPAEIVDDNESINLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNEYGENEFTYLDSNTAVDSTMEMDESFNDISDVQFEMQPLNLQTQHIEDNYNFIDIRGLNDMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSRSDGFHDEHNKTPVKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGIIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSANSIFKCYFCQFFVKDEPELIQHLLLHGITDPEDYIAKASGTKSPGPEPPPPVPTPLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRTETEAELEASTSAQNKFDFQMNLDEIPFVWVSAKNEFHKMYKCRYCSYVNAIKCKIPNHEKIHCIVFENNDTTIYKCLECKFTCDNAGRLAEHSKSHGEIYGRIYCPVEYDVPDEEQITKLRKVIEIEKSANPESFSRDEGTTHENRELKILYFCQKCPARFFEEGEIDTHEKCHDVTLPHKCKSCDFSVTEESELAAHDTVHTDEYHTKTKMLKFVHHSHPSHRQPVLELTHCPNTSDITWIATGPSKVEYIESPMKKTNDTKHAPKQYSCKQCPAKFFKSSALTYHMGLHGGDGEHKCKKCNYAVKNIGNLGKHELLHDNENKTNCDYESGEDMDYKNIPLSGTDLFQRKTEAQKRVLNDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKDNNDFTESEHQEDVKQEDSSDNIKLAIKTMPKGTAKSDFQQFSISDQQTLRLLQRRRSMNNSGKDPNASETSPIKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDVMNAGSHKCSHCDLVVVQSHFLREHLKTHFNYHKILIPECFVANEAVSFTITKLDEDSESVDLKLDLQNKSFACNDEKIFVKIKTGELLVE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00726922;
80% Identity: -