Xsex016476.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Xestia sexstrigata
Gene Symbol
egg
Assembly
GCA_941918865.2
Location
CALNXB020000284.1:1034417-1085364[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 5.3 1.6e+04 -3.8 0.1 29 38 1851 1860 1820 1861 0.68
2 2 2.8e-13 8.1e-10 38.7 0.0 4 73 1892 1954 1889 1958 0.88

Sequence Information

Coding Sequence
ATGAGTGATAAGGAAGAAAAGGACAATAAAGAAAAAGAGATTGTGCGACCAAATCAAGACGGAGGTTCCAACAACCCAGAATCATTAACTGAGGGTAATGTACTATCTTTGGATTCGAATAAAAATACCGAAAATAGTATCACCGAAAATATGCCTCGATCAGCAGCTACAGAAGGCTCTGGAGATAATGCCGGCCGCATTGTTCAAGAAATCTCTGAACTTGATAAAATAGAAGCAGAATTGACTGAAATGTCAAAGGAGTTAATAAATACTGATGTAGGCATAGGCAGTGGTGATTATACAGCCAAAACAAAGGTCAGCGACATAGATGATAAAATAATTGAGGACATAAATACTGTAATTAATGCTAAAACATCCAAAACCGATGTAATTGCAGAGAAAGTTAGAAGTAATAATGATCTTCTTAAAAAATGTGATGACATAGAACTCAAAAAGGCTGATGATTTAGACGAATTTGATGATGAAGATATGCAACTAAGATGGGATGAGGATGATGATGCTAGCAATCAACTTGAGGGTGATGACAACGCAAATGTTGCCAATAAGAATGATGGTATTCTGTCAGAAGACAAACTTTTGGAAGATTCTATTGATGTTTTAACTGAAAAAGACAATCTTGAAAGTGTAACATTAAGAGACACTTTTATAGAATCAGAACCTAGCCCAAAAGTGGACATCCAAACAGACGAGGCTGATCTTGAAAAAAGCTTGGAAGATGAGCTTTTAGAAGAAACTGATGTTCATACTGAAGCAATAAAAAAACCTGAAATGGTTTTTTCTGCAGAAGAAAAATTGGATCGAGATTTCCTAGAAGACAAAATACTTGAAGACTCTGAAATGAACAGCAATACAGAATTTACAGCTCAGTCCAAAGAGATTATTGATGTGGAAAATATGAATGAACAGATAAAAAAGACTAAACCTGCAGAGAAACTAATAAATGAAGATGAACTGACACATTCTACTGAAACATTACAAATGACATCTACTAACAATGATGTTTTGTCAAAAGATAATCTTTTAGTAGAACCAGATCCTAAAGACGAATGTCTTGAAATTATTCCTGTAAAAGACGCAGAAAGTTCTGATAATATTGCGGAAAAGGAATTCCCAATGAACAAAGAACTAGATGATGATGTTCTGCTAGAAGAAAAGCTCTTAGAAGAACCTGAAACAGCTGAAGTTATTCCTGAAATTGATTTAACAATGGAAGTTGATGATGAAAATGAAGCAGAGTTACTAAAAGATGATGGAGGTCAAAACTCTATGGATGTTGATAGTACTGATCCATCTATTGAAGATCAAGCGAAGATAGAAGACAAGATTACGGATCTGCCAATGGATGATGAATCTGAAGTAGGAACTAAAGAGATAGCTCAAACTAATCTTGAAAAGGTTGATATAAATCGAGCAACAGATGAAATCAAAGTAATGAATGAATCTGATGCACAATTACAAATGACTGAGAAGATCATTCATCGACCGGTTGAAGATACAACCAAAACAATAGAGGTTATCAAAGAAATACCTGTTGAAGAAAAATCTGCAACAGTGGAATTTGATAACGAGAAAGCTATTGAGGATCAAGCTAAAATAGATGAGCAAAATATTGATTTAGCTATCTCAGAGATGGAAATTGTAAATCAACCAATGAATCATGAGAAGAAAATTGTTGAAAACAGCAAAGTACAATTAATTGTAAAAACAAATACAACTGAAGAGTTTATCAAGACTCCTGAAAAATCAGACGCACTGACTGTTTCTAATATTCCTAATATTGAAATTGAAGGACAAGAGGAATCCATCCCAGATAAATCTACACTTGAAAAAGAAATTAAAAGCAAAAAGGAGCAAGGGCAACCTAAATTGAATACAGAAACTGTACATGCACACATTAATTTTGAAAAATCTAAAGAAATTGCTGTACTCAACACAAGTTTAGACAAAAACAATGTGTTTGCTGAAGTTTCACCTAGTTCTTCTCCAATATTTCGAGATAGTCTATCACCAATCAAAAGTTTCCATGGTTTAAATAAACCAGATGTAATGCTAGAAATACCTACTCAAGAATTAATAGACATGGATATGACAGATTTATCTATGAATCTAGACCAATCTGAAGTTTTAGACAGTAATGACAGAGGTCCAAATATAAAAAAAGAGTTTGAAGATGACACAATTGATATGTCTATAGCTGAGGATGACACAGTAACTGAGAAATCAGTAGATAATATAACTAAAGTTGTTGGTGACTCAACAAACCAAAATGCAGTAGATCAAGATACCATAGTTACTGAGACAAAAGCTGATAAAATTACTTCTGAAAATGACACAGCAAATGAAAAATCAGTAGATCAACAAACCACAGTAACTGAGGCAACAGTAGATGAAATACCAATAGAAAGTAAAAGTGGAAAAAAAGAAGAAACTGTAGTTGAAGCGACTATTGAAGAAAATATGGAAATACTGTTTGCTGATGTTGAACCGGAAGTAGCTAAAGAAGTTCCTGATTGCGTTGGATCCACAAGCGAACAGCCATCGACTTCTACCACACAAATGACTCTGGACACATCGGATGAGGTTCCTGATGCAGAGGTATCAGATAGTCTGGGACTGTTGGCTGAGTCTACGAGGGTCATGGAAGATGATGAGGAACACGAAGATGAAGATGATGGTGATGAAGATGGTGATGATGATGATTTTGATCAGGATGAAAGCAGCAACCAAGTCTCAGCGGAACAATCGGAAGACTCGAATCCACCAGCCATAGAGTCTGAACCAGTGACGGAGACGGAAGACAAAGAGCTTGAGTCGCCAGCCCCTAAGGAAAGCGAGTTTCCGTTCTTACGTGATAGTTACCCCCAGGATAAGGCGGAGAAGGTGCATATGGAGTATGGGACGATGGAATTACAGGCGGAAACAATAAATGAGATGAGCGAAGAGACAACATCAGCTGTAGAGGCGTTGTTGAAAGCTGACAAACCTGTCATTGAGGAAGCTAAGGCCCCAAAAGAAAAAGAAACCCCAGAAGAAATGGATATAGAAACAGTCAAACTGTCAGACACGTCTGACAATGAGACTGACGTTGAACCTGCAGTGGGTTCAACGGTTGGCAAGACAGTGGCTGAAGCTGAATCTAGCAAGGAGGTTGAAGAAGAGCAAAAGAAATCACCATCGAAATCCCCACTCCAAAGCAACGCTTCCCCCAAGGGATCACCAAGCAAGCTGAAGAACTTAGCTATAACCGCACAAGCAGCTAGATCCGTTGTTAATATTGTGGATTTGGAAGAGAGCAGCTCTTCAGACGATGATATACAAGAAACGGAAGTCCAAAAACAGCCATTACCGGAACCAGAGACAAAAGACGACAAGCCTGCTTCCCCCGACCCGGACTCAGCAGTTACCAGCGTCAACATACCAACGGGCATTGAAATAATACGCAGTGTGTCTTCCGGCGGAATTACCTCGGAGATTACCACTAAAGATGGGGAAGCTGTGATCAGTGGGGTACCTAAACCTCCGCCGCATAAGCCTGCCAGATTGAATACGAGTGAAGTTTCGATCAAGACTGTTAGTTCCACCGAACCAATGGTTATACCTGAAACTAAGATAAACGAACAGACACCAACACAGTCTAAACCTAATCTGAGTCTAGAAATATTCAATCTAGATTCTGACGAAGAAGATAGTTCTGCTAAAGAAAAATCCACAACAAAACCCCAACACGAAATGACGCCCCTGGAACTGGAAAAAGCAAGAGAAACATCCAAATGTATCAACTATGGTTGCACTAGCGACAACATAGTGCCATTCAGGGTCGCGGAGGCCGCAGAGCTAGCGTACTACGACGCCAACAGGAAGAAACGCGCCCAGGTGTGCCAGCCGTGCGCTACTGTCGTCGCTGACAGGACTAAGAATCTTATCCAAGGCATGAAGGATCTAACTCCTCTTCTAGACCTGGACATGCGCAAGTCTTCACAGGAACTGGTGGAGATATCAGATTCTGACTCTGAAGACGAGAATATGAATTCTGAGGAGCCGAAGGAAACCATTGGAAAGGAGGGAGCTAAAATCTTAGAAGAGAGTCTGAGCCAGTTTTTGAACGACACTTGGAAGAAATACAATATGGATGCACGGCTCAAAGAGACGCAGATCATGTTGGATGATGAAATCGAGAAACTTGAACAGGACAGCAAAGAAATCGACGACATGCTGAACGCATGTCAGGTGGCGACAGACAAGCTTCGCAACGAGTTGTACGCAACATTCGAGTGTCGCCTGCAACAACTGCCCCCACTAGTCATACAAGACACGCCTGAGAAAAAaTTTATCGCCCAAGAAGAGCATGACGTCACCCCTCCTGTTGTTGGAGAATCAGCTGCAGTTCGTCATGCCAAGCGTCGTTTGTCGTCAACCACTAATGAGGTGCCTGCCAAACGCCCCGCCATACCGCTGGGATATGCTCCTTTAGATTCTGCAGACGCTAAGGAAAAAGCAGCTATTCCCGCACCGGAAAGTAAAATAGATGATGACAAAGATATATCAGTAGTGAAGCTATCAGCGGAAGCGGCCCCGGCCGACCTCCCCCCTCCCGGCGAGATCTCCCGCCCCCCCTTGCGAGTGGGGATGCCGGTGTTTGCCATGAAGAACGCCTTCGGACCGTTTCTCAAAGGCAAAGTGCTGGAGATACAGCCCAAAAATGTTGGTGGGGGCAACCCATTCTCTCTATGCCGCGTGAGATTCGACCATAAAGCCAAGTCTAACGGGAAGGTGCTGCAAGCAAGATCCATCGCTTATGCAGAGCCCGCTGACGTTAGAATGACTATTGGTACTCGTCTCATAGCTCTGTTCAAAGATTCGAATAAGCGCGAGTCTTACTACTCGGGCGTGGTCGCTGAAATACCGAATCCGGTCAATAATTACAGATACCTAGTTTTCTTCGACGATGGCTACGCTCAGTACGTACAGCATCAGTATACCCGCCTAGTTTGCGAGAGCTCCCATCATGTATGGGACGAAGTGCATCCATTCTCGAGGGAGTTCGTGCACAATTACCTGAAGGCGTACCCTGAGAGACCCATGGTCAGACTGCACACGGGGCAGCATCTGAAGACCGAGTGGAACGGAAAATGGTGGCCATCCCGAGTGACCCGGGTAGACGCATCATTAGCTCAGGTGATGTTCGTGGAGGATGGGCGGCGCGAGTGGATCTACCGTGGTTCAACACGACTCGCACCCTTGTACCTTGAGCTACAAGCCGCGGAACGACATCGGCCCCGACCATTGCCCCGGGGCAAGGCGCCGCCTAGGCTGAATATGCCATACGTGGAGTACATTCGGTCAGATGAGCAGGAATCCAGCAAGCCAACAGACGCGCAGGTGCAGGCTCAGCAGGAAATGCAAAAACAACAGCTGCAGCGAGATGAGGAGATTCGTCGCCAACGCGCCGTGGCCAAGAAGTCCACATCAGCACCTCCTCAAGTGTACCCGCCGGCGCATCCGGTCCTGCCGCCTCTTAATACAGATCCTGTCACCAGCAGAGTTGTGTACTACACACCAAAGAATGCAGTCAGGCCATTGAAGATGGTCCCACATAGATGCACTCCTAAATGCAAGAGAGGCGACGTGCTTTCACTAAAGGAGTTGAGAACTTATAACCCGCTGGCCAAACCACTGCTTAGCGGATGGGAAAGACAAATAGTCCGCTTCAAGGGCCACAAGGACGTAATGTACCGCGCGCCGTGCGGGCGGCGCATACGCAACATGCGCGAGCTACATCAGTACTTACGTTCCATAGACAGCGACCTGCCTGTAGATCTCTTCGATTTCCACTACTCCACGCACTGTCTGGCGGAGTTCGTGTTGAACAAGTGTCTTGTGGGGAAAAAGGACCTGTCCCACGGCAAAGAGAACGTCCCGGTGCCGTGCGTGAACTACTACGACGACTCCCTCCCGGAGTTCTGTTCGTACAACACCGAGCGCACTCCCACCGCCGGGGTGCCGCTCAACTTGGAGCCCGAGTTCCTGTGCGGCTGCGACTGTACCGACGATTGTCAGGATAAATCAAAATGCGCTTGCTGGAAGATGACGCTAGAGGGCGCACGGACCATTGGCCTGGTCGGGAGCAATGTGGGCTATGTCTACAAACGATTGCCCGAACCGTTACCTTCTGGAATATATGAGTGTAATTCTAGGTGTAAATGCAAGCATACGTGTTTAAATCGCGTCGCACAGCATCCACTTCAGTTGAAGTTGCAGGTATTCAAGACTCCGAACCGCGGTTGGGGTATCCGCGCACTGAACGACGTGCCCAAAGGCTCCTTCCTCTGCGTGTACGCAGGTAACCTGCTCACAGATGCTACGGCTAACTTGGACGGGTTGAATGAAGGGGACGAATATTTAGCAGAATTGGATTATATAGAAGTTGTCGAACAAATGAAGGAAGGATATGAAGAGGATATTCCTGAGGCCGATAAGAAATTAGACAAGGTGACACATCACACGGGCTCGAACTCATTGGTGGGCGTGGCCAAAAAGCACGCTGTCTCATCTGGCATCGTGCCCGACAGAGATAGTATCAGTGATGAGCAGTTAGGCGCTAGTCTTCACGCGCGTCTGAAAGAATCAGGTAAGGATGGCGGAGACAGCGATGAGGAGCAATCGTCATCATCTGAGGATGAGGACACCGCCTCCAAGACTGACAAGGAAGATGACGACTTTAGACCTGGGAGCCTTGGGCTGGGACTGGGAGCTGGCGTTGCGGAGTTCAACAAACGCCTCCGTAAACGCGAAAAATCAAAGAAAGATAAAGAAAATGCGGCGGCTGACGATAAAGATTTAACTAAAGATACAACAAAAGATATTAAAGAACAAAAGGAAGAAATGAAGAATGCTGAAGATGATTGTATTACCATTAGTGATGATGAAGAAGTACGAGAACCTTCAAGATTCATGGCACAAACAAAAATGGGAGCTAACGAGTATATATCTAAATACAAATCTGTTCGCACACTTTTCGGTAAGGACGAGGCGTGCTATATTATGGACGCTAAGGTTCAAGGCAACATTGGAAGATATCTCAATCACTCCTGCTGCCCCAACGTGTTCGTACAGAACGTCTTCGTGGACACCCACGACCCTCGCTTCCCCTGGGTGGCGTTCTTCGCGCTATCTCACATAAAGGCGGGCACAGAGCTCACGTGGAACTACAACTATGACGTGGGTTCGGTTCCCGGCAAGATACTGTACTGTTACTGCGGCGCCGTCAATTGTAGGGGGCGACTTTTGTAA
Protein Sequence
MSDKEEKDNKEKEIVRPNQDGGSNNPESLTEGNVLSLDSNKNTENSITENMPRSAATEGSGDNAGRIVQEISELDKIEAELTEMSKELINTDVGIGSGDYTAKTKVSDIDDKIIEDINTVINAKTSKTDVIAEKVRSNNDLLKKCDDIELKKADDLDEFDDEDMQLRWDEDDDASNQLEGDDNANVANKNDGILSEDKLLEDSIDVLTEKDNLESVTLRDTFIESEPSPKVDIQTDEADLEKSLEDELLEETDVHTEAIKKPEMVFSAEEKLDRDFLEDKILEDSEMNSNTEFTAQSKEIIDVENMNEQIKKTKPAEKLINEDELTHSTETLQMTSTNNDVLSKDNLLVEPDPKDECLEIIPVKDAESSDNIAEKEFPMNKELDDDVLLEEKLLEEPETAEVIPEIDLTMEVDDENEAELLKDDGGQNSMDVDSTDPSIEDQAKIEDKITDLPMDDESEVGTKEIAQTNLEKVDINRATDEIKVMNESDAQLQMTEKIIHRPVEDTTKTIEVIKEIPVEEKSATVEFDNEKAIEDQAKIDEQNIDLAISEMEIVNQPMNHEKKIVENSKVQLIVKTNTTEEFIKTPEKSDALTVSNIPNIEIEGQEESIPDKSTLEKEIKSKKEQGQPKLNTETVHAHINFEKSKEIAVLNTSLDKNNVFAEVSPSSSPIFRDSLSPIKSFHGLNKPDVMLEIPTQELIDMDMTDLSMNLDQSEVLDSNDRGPNIKKEFEDDTIDMSIAEDDTVTEKSVDNITKVVGDSTNQNAVDQDTIVTETKADKITSENDTANEKSVDQQTTVTEATVDEIPIESKSGKKEETVVEATIEENMEILFADVEPEVAKEVPDCVGSTSEQPSTSTTQMTLDTSDEVPDAEVSDSLGLLAESTRVMEDDEEHEDEDDGDEDGDDDDFDQDESSNQVSAEQSEDSNPPAIESEPVTETEDKELESPAPKESEFPFLRDSYPQDKAEKVHMEYGTMELQAETINEMSEETTSAVEALLKADKPVIEEAKAPKEKETPEEMDIETVKLSDTSDNETDVEPAVGSTVGKTVAEAESSKEVEEEQKKSPSKSPLQSNASPKGSPSKLKNLAITAQAARSVVNIVDLEESSSSDDDIQETEVQKQPLPEPETKDDKPASPDPDSAVTSVNIPTGIEIIRSVSSGGITSEITTKDGEAVISGVPKPPPHKPARLNTSEVSIKTVSSTEPMVIPETKINEQTPTQSKPNLSLEIFNLDSDEEDSSAKEKSTTKPQHEMTPLELEKARETSKCINYGCTSDNIVPFRVAEAAELAYYDANRKKRAQVCQPCATVVADRTKNLIQGMKDLTPLLDLDMRKSSQELVEISDSDSEDENMNSEEPKETIGKEGAKILEESLSQFLNDTWKKYNMDARLKETQIMLDDEIEKLEQDSKEIDDMLNACQVATDKLRNELYATFECRLQQLPPLVIQDTPEKKFIAQEEHDVTPPVVGESAAVRHAKRRLSSTTNEVPAKRPAIPLGYAPLDSADAKEKAAIPAPESKIDDDKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVFAMKNAFGPFLKGKVLEIQPKNVGGGNPFSLCRVRFDHKAKSNGKVLQARSIAYAEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQYTRLVCESSHHVWDEVHPFSREFVHNYLKAYPERPMVRLHTGQHLKTEWNGKWWPSRVTRVDASLAQVMFVEDGRREWIYRGSTRLAPLYLELQAAERHRPRPLPRGKAPPRLNMPYVEYIRSDEQESSKPTDAQVQAQQEMQKQQLQRDEEIRRQRAVAKKSTSAPPQVYPPAHPVLPPLNTDPVTSRVVYYTPKNAVRPLKMVPHRCTPKCKRGDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKDVMYRAPCGRRIRNMRELHQYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLVGSNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKVTHHTGSNSLVGVAKKHAVSSGIVPDRDSISDEQLGASLHARLKESGKDGGDSDEEQSSSSEDEDTASKTDKEDDDFRPGSLGLGLGAGVAEFNKRLRKREKSKKDKENAAADDKDLTKDTTKDIKEQKEEMKNAEDDCITISDDEEVREPSRFMAQTKMGANEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAVNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01533075;
90% Identity
-
80% Identity
-