Basic Information

Insect: Xestia ashworthii
Gene Symbol: Zfa
Assembly: GCA_950022955.1
Location: OX465553.1:8203586-8212046[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0077 1.1 11.4 1.1 3 23 650 671 649 671 0.96

2 23 0.25 35 6.7 0.3 1 22 1056 1077 1056 1077 0.95

3 23 8.9 1.2e+03 1.8 0.4 1 22 1119 1140 1119 1142 0.82

4 23 0.02 2.7 10.1 4.8 2 22 1152 1172 1151 1172 0.93

5 23 3.1 4.3e+02 3.2 0.1 3 23 1181 1202 1180 1202 0.89

6 23 0.021 2.9 10.0 0.2 3 23 1223 1244 1221 1244 0.96

7 23 0.0039 0.55 12.3 2.5 1 23 1250 1273 1250 1273 0.95

8 23 0.15 21 7.4 0.0 1 23 1299 1322 1299 1322 0.90

9 23 0.022 3.1 9.9 3.4 1 23 1327 1349 1327 1349 0.97

10 23 0.01 1.4 11.0 0.2 1 23 1355 1378 1355 1378 0.95

11 23 0.0048 0.67 12.1 0.8 1 23 1391 1413 1391 1413 0.97

12 23 0.00021 0.03 16.3 1.8 1 23 1463 1486 1463 1486 0.97

13 23 0.0022 0.3 13.1 1.4 1 23 1546 1569 1546 1569 0.96

14 23 0.0028 0.39 12.8 2.1 2 23 1596 1618 1595 1618 0.95

15 23 0.047 6.6 8.9 0.1 2 23 1624 1646 1623 1646 0.94

16 23 0.012 1.6 10.8 0.2 1 21 1690 1710 1690 1711 0.95

17 23 0.0005 0.07 15.1 1.0 1 23 1721 1743 1721 1743 0.93

18 23 0.00013 0.018 17.0 0.4 2 23 1836 1858 1835 1858 0.93

19 23 4.7e-07 6.6e-05 24.7 1.4 3 23 1865 1885 1864 1885 0.98

20 23 0.0068 0.94 11.6 0.3 1 23 1903 1925 1903 1926 0.95

21 23 0.22 31 6.8 0.0 1 23 1949 1971 1949 1971 0.97

22 23 0.033 4.6 9.4 0.6 1 23 1977 2000 1977 2000 0.95

23 23 0.0003 0.042 15.8 0.4 1 23 2008 2031 2008 2031 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0077	1.1	11.4	1.1	3	23	650	671	649	671	0.96
2	23	0.25	35	6.7	0.3	1	22	1056	1077	1056	1077	0.95
3	23	8.9	1.2e+03	1.8	0.4	1	22	1119	1140	1119	1142	0.82
4	23	0.02	2.7	10.1	4.8	2	22	1152	1172	1151	1172	0.93
5	23	3.1	4.3e+02	3.2	0.1	3	23	1181	1202	1180	1202	0.89
6	23	0.021	2.9	10.0	0.2	3	23	1223	1244	1221	1244	0.96
7	23	0.0039	0.55	12.3	2.5	1	23	1250	1273	1250	1273	0.95
8	23	0.15	21	7.4	0.0	1	23	1299	1322	1299	1322	0.90
9	23	0.022	3.1	9.9	3.4	1	23	1327	1349	1327	1349	0.97
10	23	0.01	1.4	11.0	0.2	1	23	1355	1378	1355	1378	0.95
11	23	0.0048	0.67	12.1	0.8	1	23	1391	1413	1391	1413	0.97
12	23	0.00021	0.03	16.3	1.8	1	23	1463	1486	1463	1486	0.97
13	23	0.0022	0.3	13.1	1.4	1	23	1546	1569	1546	1569	0.96
14	23	0.0028	0.39	12.8	2.1	2	23	1596	1618	1595	1618	0.95
15	23	0.047	6.6	8.9	0.1	2	23	1624	1646	1623	1646	0.94
16	23	0.012	1.6	10.8	0.2	1	21	1690	1710	1690	1711	0.95
17	23	0.0005	0.07	15.1	1.0	1	23	1721	1743	1721	1743	0.93
18	23	0.00013	0.018	17.0	0.4	2	23	1836	1858	1835	1858	0.93
19	23	4.7e-07	6.6e-05	24.7	1.4	3	23	1865	1885	1864	1885	0.98
20	23	0.0068	0.94	11.6	0.3	1	23	1903	1925	1903	1926	0.95
21	23	0.22	31	6.8	0.0	1	23	1949	1971	1949	1971	0.97
22	23	0.033	4.6	9.4	0.6	1	23	1977	2000	1977	2000	0.95
23	23	0.0003	0.042	15.8	0.4	1	23	2008	2031	2008	2031	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCCACCAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGgcatgtttttaaaaatgtatgTGAAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAACCAACTAGAAGAGGTGAAAATAAAAAGTGAACCACTGTCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTACTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCGCGAACGGATTGGCACCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTGCAGACAAGGGAAGAGTGCGATGTTTTGCAGCATTCTGACCATGACTCAGATACTGAAGCCGAACTCCAAACAGAAATTGATGACAGTTATGTTAATAGCAAAAGCGGATACATAtgcaaaaataaacaagttaTATCAAAAGTTCCAAAACTATCAACTTCTGTAAATAATGCTAGAGTGAAAGAAGCTTTCAAACTCAGGAAACGTAAATCAGAAGTTCGTAAACATTATCCACAACCTAAAAATGCGTGGCAGTTGTTATTCACTGATGACCTACTAGAGTTGATTGTTGCTTCTACTAATGACAATATTGTGACAAATGGGAAAAGTTTCACGGAGTCAACGAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCACGGCATAATGCGGCCGACACATCAGAATTGTAGTGACCTTTGGAACAGTGAATGTGGTGTTCCTTGCGTCAGAAATATCATGAAATACGAAAGGTTCAAATTCCTGCTTCAAAACATGAGCTTCGATAAAGAGGACGAGAACAGCATTATACAGTTCGACATAATGAAGCGTATGCGTAAAGTGTTCGAGATCTTCGCTATGAATTGCAGAACATCTCATGAGATAGAGAATGTCGCAGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATACGATATTGATAATAAGCCGCTGAAGCGGGGCTTAAAGATGGTATTGCTAGTTGATTCATCTACATTCTACATGAGCAACTTAGACGTCATCACTGACCCTTACTTTGGCCCCAAGGAGATAACGAAGAAGTTGGTTCAGCATTTGGCTGGAACTGGCAGGTCTATTGTTATGGACAGTTGGTTCACTTCTTCCTCTCTGATGGATATCCTTAAAAATGAGTACCAGTTGTATTCTATTGCAGCCCTGAACCCAAACAGTGATTTGATTCCACCGCTGTTCTTATCTCAATACAGGAAATGCCGAACATTCATGTCTGGATTTATTGATCATGAAGTATCATTGACATCGTATGTCAATACTGAGGGGAAATCCATAAATGTATTGACTAATGAACCTAGATATTACAGGAAAGGTCATATAAATCACACCACTGTTGTTTCTGTGTATAAGAAGAATCATTCTGCAGTAGAAGTTGTAGATGTTCTCATGAATTACTATACTACAATGCAACACACAAATGACTGGACGTTGTCCTTATTCTTCACTTTGCTAAACATTGCTTCTGTTAACGCTCAAGGTGCGGAGAGTGAAAACAATGAAGAAGACGAGGAAGAAATGAATGAGCCCGCACAAAATTTCCCAAAAATGCCTCACATGCCCGAGGTGTCCATCACGGTCATGAGGCCTACTGGCGAGACCCTGCACGCTCGTCAAGGTATTCACCAACTCGCTTCCAAACTGTGCCTCGTCTGCGGCCGCTCCTACAGGTATTCTCACAACGCACGCAGACATGAGCTTACCGCTCACAGCTTCGACAGGTATACAAACAAAATTACTCCTAAAAAAACCCTCAATCATCTACAACCCAAACTGAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATGCCAACAAAAATAATGCCCATAAACAAAGTTATAACGCCACAGAAACCCATTCCAATAAAAACGTCGTCAAAGACACAAAATAATTTGCCTTATCCTTTACGCATTAAAGCactcaaagatttacaaattaaGAAGAAGGAGCCTCAGATTCTGAAGACTTTGTTAACCTCTAAACCTGAAGTTCTGGTCTCAGAACCAGAAATTCTAAATTCTGGGCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCATCTTTTCAAGTTGAAGCTATTCTTACTGAACCCGATGCCGATGCATACGATGATCCACAGCAAGGCGACGAAGAAATAGATGAAGAAATGCAgaacaatcaaaatcaaaactatgACACTGTAGATATGGACTCTGAGAACGAAATAGAGATAGCTCGTCAGCAAAGTGTTGAACATGATGGCGAGGAAAATGCTGATGGGGAAGAGAATATGGACCATGATGACGACAATAACATGGAAGGTGGTCCGAGCGATAACGAGAAAGATGCCAATGACGATACAGCTGATAGTCAAGAAAacatggaagaagaagatagtGTTGATATTAAACCTGAAGAGCAAATGAAGGAAGATGATGGCCAAGAGGAGGGAGAACACGAAGAAGTAGAAATGAATCATAATGAAAACGaggaagaagatgatgatgatttgccAATCTCTCTAGCTCCCGTCGTGGAAATAAGTGAGGGATTGCAAGGTGACTCGTTCAACAGCGAAGTCATTGAGGAAGAGGAAGAGCTCGATGAAACTGTCGATCCCAATGACACCATCGAAGAGGAAGAGCAGGTTAAAGAACTTGACCCTGACAAAACATATGTTACGAAAACCCAAAGAGACTTCATCCAGAAATACCGCGATATCATTCAGCAAATCAATACGAAGCGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAGCACTTGCAGAAGAACGGACACAAGGTACCAAAACACACATGCTACAATTGTGTCATCACGTTCGGACATATTGGCGCACTTCTGAGCCATATGAGATCGAATTCTTGCACCAATCTGTGGAAGATAATTTACAATGAAAATGGCATTACTGACGACTTGGTTCTCGAAGATGAGCCGAAAGAGGTCAAGGTTGCTTACAAAGATATTTTCAATGCCAGGTCGTACGCATGCAAACTCTGCCCAGCTAAATTCCAATTGAAACAGTTTATAATGAAGCATGTTTTGGATACCCATGAGGATGGACAATCAAGGGTACCACTCTGTTGTGTACACTGCCGTTCTAGATTCAAAGATAAGAGTTTACTAAAGAAACATATTCGTAAAGGTGATTGTACAGTATATGTTGCTTGCGATTTGTGCTCAGAAAAGTTCGGGAACATGCAGGACTTCAACGACCATGCGCTAGCCATCCACGCCGGCAGTTTCGATCAGTCGGATAATCAGAGCAAATGTGTTGACGGTCGACCAACAGATTGTCCTTTGTGTGGAAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATTATACATGCTGAAGAAAAACCTCATTACTGCCAGCATTGTGACGCGAAATACGAACAAGCTACTGATCTAAACAAACACATCTACATGGAGCATTCTGACAGAACACTAGGCATGCCGCCTGCTGAGCCGGATATGTCCATAGTGAAGGAGGAAGCTGAGGAGTACCATTACTCCTGTACGGAATGTAATGCTATATTCGAAACTGTTGATGCGTGGACGGATCACCAAGTCGCTGAACATAACCAGGTGGCCCACCACTGTGACCAGTGTGAGAAGAAGTTCCTTCGCCCTTCGGAGCTGGCAGAGCACAAGAACACCCACTTGAGGGTAAAGTTTTACCCTTGTAGTGTGTGTCCTAACTCTTACAGTACTCCACAGAAACTGTCTGAGCATGTGCAACAGTCGCATCCAGGAATCGGCGCGGTCGCGGCAGCCGAGTCGGAATTCTTCTGCGACATCTGCATAAGAGCATTCAAGAGTCGCCAAGCTTACTCAAATCATATGCGTATTCACGCTAAAGTACCTACTACTAACAGGAAACCAACTCCAATCAAAGAGGGATTCGCGCCTCAAATTATTGGGAAACCCATCAAGCAGTATCCTATGGTTCAACCGGGTTTTGTATCTTTTAAACCTAATTACAATATCCCTAACGCTCCATATTCTTGTGATATTTGTGGTAAAGGAttcatgcataagaaaaatatatgGAAACACAAGAAAGTGTTGCATGCTGATATTTTAGTCGATAGGCATGATAGTGAAGAGAACACTATGCAAGCTTCAACGGAAGAAGAGGAATTCAATCCTGATGAGAACGGTGCTGTTCTCTCAACGCCACAATTTAATAGTTTTAACTTTACAAACTTCCCAAACAATGCTCAACAATCAACACCCGAACCAATGCCATATTCGTGTGACTTATGTAGCAAACGGTTCCCGCTTAGGACCAGTTTATGGAAGCACAAGCGCGCTAAACACGGAATTGTAAACCCCAGCACTAGTGGTAACAACGAAACATCCACGCCGTCCGCTAGCGGGGAAAGCAGTAGTCGATCTAGCTGCACTATATGCAGAATCACATTTTCAGATAAGAAATCTTACTATCGCCATCGAAAGAATGTCCACAAATCTACCGTTCAAATGTGCAAAATATGTGGCAAACCGCTAAGTTCAACTTTGGAATTATACGAGCACTTGAAAGCCGCTCATGCAAGGGAATTACTGGGATATAACGCTAACCAAGGCTCCAGTAAATCACAAGATATGTCACAAGAGATGGAGCCCGATTATGAAAATGATCAGGAGTCTATCGACCCCAGCGTTGATTACCAAGCGCGGTACCCGTGCGATACATGTGGCAAACAATTTGTTGGTTTGCTAGCTTTGCAAAACCACCAGTGCATCAATCAGATAGCATCACAACCACAGACATTTGACTGCGAGATTTGTCACAAGAGTTATACTTCAATATCTGCGCTAAAAAGCCATCGTGGGTGGCATTTACGTTCGCCTGACGGAAAAGCAGCCGCCAACAATTCTGGCCTGTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGCAAACATGAGGTCGTGGACGCGTCCCAACTGGCTAAGGTCACACACACCCCCACTCCCCCACCTGTCTCTGCAACCGCAGCGAAAAGAAGACTACCACCAGAGGTCGAAGTGACAGTCGTAAATCCGAATAAGAAACTGCGCTCAGACGACTCTGTCGACTTAGATATGCAAAGTTCTGGTGCCATCGAGGATAAGTACTGTACGATTTGCGATAAGGAATTTACGAAACGAGCGGCGTACCAACGTCACATGGACGAGGTACACCAACCGAACTCTGTGTTTTGCCCGGTCTGTGACAAGAGTTTTACAAGGAAGTCCACATTGCTCATTCACATGAAGAAACATTACGAGAGCGGTGAGGGCAGTTCCTCTGCTACAGGTCAAGGAGACGATGATTACTCCTGTGATTTGTGTGGAGCTCAGTATGACAATGAACAGGCATTGAGGGCGCACCGAGCGCGGCACCACGGAGAAGATGAAGAGTCAGCCGAAGAGAGTGACGATGGAAATGTTCCTATTGCTCCTCCCGGTGAATTCACATGTGCGCAATGCGGCGATGGCGTCGCTACTCCCAGGGACCTCATCGCCCATCGCACAATGCACGCAACTCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCGTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTTCCGTGTGCCATGTGCGACAGGTTTTACATGAACAAGAAGAGCTTACAGCGGCACATTGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGNQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGYSNKVQPEGPPILASLGLTPRSDKKCVDPRTDWHRVHAILDMVQDNEVIDSLQTREECDVLQHSDHDSDTEAELQTEIDDSYVNSKSGYICKNKQVISKVPKLSTSVNNARVKEAFKLRKRKSEVRKHYPQPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQNCSDLWNSECGVPCVRNIMKYERFKFLLQNMSFDKEDENSIIQFDIMKRMRKVFEIFAMNCRTSHEIENVAVIDEIIVPVYGPCPFRYDIDNKPLKRGLKMVLLVDSSTFYMSNLDVITDPYFGPKEITKKLVQHLAGTGRSIVMDSWFTSSSLMDILKNEYQLYSIAALNPNSDLIPPLFLSQYRKCRTFMSGFIDHEVSLTSYVNTEGKSINVLTNEPRYYRKGHINHTTVVSVYKKNHSAVEVVDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQGAESENNEEDEEEMNEPAQNFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMPTKIMPINKVITPQKPIPIKTSSKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDPQQGDEEIDEEMQNNQNQNYDTVDMDSENEIEIARQQSVEHDGEENADGEENMDHDDDNNMEGGPSDNEKDANDDTADSQENMEEEDSVDIKPEEQMKEDDGQEEGEHEEVEMNHNENEEEDDDDLPISLAPVVEISEGLQGDSFNSEVIEEEEELDETVDPNDTIEEEEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYVACDLCSEKFGNMQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDAKYEQATDLNKHIYMEHSDRTLGMPPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAAAESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPTPIKEGFAPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFTNFPNNAQQSTPEPMPYSCDLCSKRFPLRTSLWKHKRAKHGIVNPSTSGNNETSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSQEMEPDYENDQESIDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIASQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDASQLAKVTHTPTPPPVSATAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQSSGAIEDKYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNEQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -