Xdes018899.1
Basic Information
- Insect
- Xanthorhoe designata
- Gene Symbol
- ibtk
- Assembly
- GCA_963582015.1
- Location
- OY757049.1:3301749-3317556[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 5.9e-14 2.2e-11 44.4 0.0 7 79 553 624 547 630 0.88 2 4 2 7.7e+02 0.9 0.1 61 107 700 747 691 749 0.76 3 4 1.1e-11 4.4e-09 37.1 0.0 8 106 739 841 733 845 0.81 4 4 1.2 4.6e+02 1.6 0.2 78 107 845 874 842 877 0.88
Sequence Information
- Coding Sequence
- atgaGTAAACATAAAGCAGAGGTGGATTGCACCAAATGGTGCAGGTCTCGAAGCCATGGACAGGTCCTTACCAGTGCCATCACCAAGAGGTCCATAACAGACAAGGATCTGGCCGGCTATATTAGAGGAACATGCGCTAATTTTATTAAGGCATTTGACTTTGAGGGTCGAACAGCACTGCACATGGCTGCGTCTCGCGGTAGAGTCGAGCTGATGAGCTGGCTGGTGCGCCATTCTTCTGAGGCTTTTGTCAATGCACGCGACCGGGAATCAGGGTACACTCCGTTGCATAGAAGCATATTCTATGGCCAAGTCAATGCGGCCGTTGCTCTTATGAAAAtagGTGTAAAAACAGATATAGTCGACAAAGATGATTACAAAGCGCTAGAACACGCATTGCTAGATCGCGCATACATGTACAAACATGATCTACTGCAACCTTGCGACTCATATGTATGGGGCACCAACACCAACTATACTCTAGGCACGGGATCCAACCAACCCAGAGCAGTGCCTGAAGCGTTGACTACTTTTAATAAGGCGTATACGAGTGTGAAACAGGTATGCATCGGCAAGTTCCACACTATATGGCTATGCGACAGCGGTCCGACCCCCGGCACCGTGTGGTGTTGCGGGCAACTCGCTCGCGCCGGCGCCCCGCACTGCACAGCGCTGCGCCCCGCACCGCTGCGTCTGGCCGAGCCGTGTGTTTGTGCTGCCCTCACTCTCAACTCTACTATACTGCTGCTGGAAAGCGGGACGGTGATCCAATACTCCTTAAACAGCAACGACAACATCAGTCAGTCATGCACAAAAACGCCGTCAAGCATCAAACTCCCGTCAGTTAAGCCGCTCATCAAGCTGTCAAATCCTCTCGGGGTACGCGCGGGAAAATCTCATGCAGTTGTGTGGAATAAGAATGCTGTTTACACTTGGGGCACTAATATTGGTCAGTTGGGCCATTCGCAAGAGGACAAGATTGTTAATGCTCCTAAAAAGGTAACAATATCGATGAACACGAAAGAAGACGCGGGCATACAGCTGGTTGAAGCTGGTGATGCTGCCACTGTCATTACTACCGCGCGAGGAGATGTATATCTACTGCACAAATATATCTGCAAGAAGATCGCTATTAAACAGATAAACCTACGGCAAGTTTGCGTGGAAGGGAAGATGAGCGATCAAGGCGCGTACTCGAGAGTTACAGTACTACTGCTTACTAATGTCGGGCAGCTACATATCTGGCAAGATACTACCAACAAACTTACCAGATGCGTATTCGGCATGGTCCACCAAACTTTAGTAACCCATATGGCGTTAACCCACGATGCACTCTACTTCACAACTAAACAAGGCGAAGCCTACATCGGAACCATATCCCGCAAAACAGCTACGCCATCTCAGCCAATCAGGAAAGAGAAAGAGAAGGACGGAAGATCGGCCCTGGTGAAGTTTTTAGAAAAGGACGACTGTACTTCTGTCAGGATCGTGAAGATTCCGAACGTGCATCGCGCGGTGTCCATCGCTGTTGATTCGGAGGGATTGAACTTTTCCATTTTACAGTCGAAACCAACGTGCGGTCTGACGTCCATCCCCGAACTATCGCCGTCCTGCTTCGCCAAGCACATGGATTCTCTGCGAGAAACGGCCGCCGAAGACGACATCTTACACGATGTTGTCTTTCAGGTCGGTACAAAACGGTATCCGGCGCACATGTTCATAGTAGCCTCTAGCAGTGAGCATCTCTACAAATTGTACCAGGACACCATAACTACGCCGGGGGAGAAGCCAATCATTGCTCTTACGAACGTACTTCCAGATGTATTCGAGAGACTCCTAAAGTTCATGTACACGGGAAGCTGCGACGTAGCTGAGTTGGGGCCGTGCAGTCTGAAGATAAGGAGGGAAGATATCGTGGGGAAGAAAGAGAAGGACGGCGATAACGAAGAGGAGATTGAAAATCCAATGGAAATCTCCGCATTTGAGGTCCAAAAAGACAAGAAACGTAAGAACAAGCGAGCTACAGAGACGCCGCGTCCGATCCATCCGTACTGCGACCCCGTGAAGTTGGTGCAAGCGGCGGCCAAGAGACTGCACATCATGGCTCTACACAAACTGTTGGACCACTTCTATTACAAAGATGGAAAAGTCTGTCTTAAAGACAGCGCAGACTACACAAAGAAAGCGGCGATGCATTGGGAGAGGGAGTCGTTGCACGAGTTAGTGGACACCAACGTTTGTACCAAAGATGGTGCATTGATACCCGCTCACAAGTGTGTACTAGCCGCAAGATTGGAGTACTTTAACGGCATGTTTATGCATTCTTGGACCGAGAGTAAATTATCTACTGTGACATTGCCGATTAACTACGGAATTCTACTACCAGTTATAAATTTCCTATACACAGACTCTTGTCCAGAAATCGAGAATTGCAATGAGAGTATCGATTTTATATGCAACATGCTTATTGTAGCTGACCAGTTGTTCATATCTAGGTTAGGCGAAATGTGTGAGATCGCTCTAGCTAATATGATTACTCTGAAAAACTGTGCTGAGCTGTGTCAGTTCGCACACACCTATAACGCTACCCAGCTCAAACAATGCTGCATGGAATTTATATCAATAAACCTATCTTCAATTCTCGAGAACAGATCGCTAGACCCCATAGAAGATGCTCTACTTGATGACATCACAAAATACTATTGCAAATTCAATCCTATAATGTCTTCTCGAGTTATAACACCATTCTTTAACGCACCAAATGACGATACTATTGAGGAATTTACTAAAAACTATCCCGTAGACTTAGATTTTATTGATGAGGACGTGAAAAGAGATGATAGTATTCTAGAAATCAAAAAGAAAAAGTCTAAGAAAGTTGAATACACGGATAGCGAAAAGGCGAGGATGAGATATGAATCTGTCAGCTCTGTTACATCATTAGATTTGTCCAATGAAGTATCGGGCGATATAACACTATCCTTGACCAAAATAAAGGACGAAAAAGAAAAGAGTTTcgagaaaaaattaaaagaaaaatggACAGAGGTTCCATCATCTCAAAAGCAACAGAAAGTCGTGCAAGCGAGATTAAAAGCTATCAGCACCGCTAAAGACATCCTAAACGAAACTCCAACAGAAACGTTTACAAAACTCGTTAAATCAAGCTCTATAAACATACCAGAAGCTCACATAACTAATTCACGGATGTCGGTATCTCCTAAAGAGTCGCCTACCGCTGATCTAGCAATGAGCCCGGTTTTTATAAGCCATGTCGGTCCGAAGCTGTCTCAGAAGCAGCGTAAGAAACTAGCGTTAGAAGGAACCGAGCAATCTCCGCGGAGCATGACAGATTACTTCAATAAGAGTGTCAGTCCACCTGAGAAAAAGAATCCTTGGAAAGTTATAGAAGCGCCTGTTGCAAGCAGCAGTCCTAAGGCGAAGCCAGTTCAGTTCAATCAGATTTTAACAGATCAGAGGAAACAGAAAGAGGACTTTTCGAGGATTATGACTAAACCTTTGGCTTTGACGCAGCTTGAAGACAAGGCAATCGAACAGCTGGAGAGATTCTACAATGCCCATGAATCTGATGAAGAGTACATCATTGTGCAGCGCATTCAGCTTCAAGTTTCCTCACCGCAGTGGGTGCACACTGCCAATAAGTga
- Protein Sequence
- MSKHKAEVDCTKWCRSRSHGQVLTSAITKRSITDKDLAGYIRGTCANFIKAFDFEGRTALHMAASRGRVELMSWLVRHSSEAFVNARDRESGYTPLHRSIFYGQVNAAVALMKIGVKTDIVDKDDYKALEHALLDRAYMYKHDLLQPCDSYVWGTNTNYTLGTGSNQPRAVPEALTTFNKAYTSVKQVCIGKFHTIWLCDSGPTPGTVWCCGQLARAGAPHCTALRPAPLRLAEPCVCAALTLNSTILLLESGTVIQYSLNSNDNISQSCTKTPSSIKLPSVKPLIKLSNPLGVRAGKSHAVVWNKNAVYTWGTNIGQLGHSQEDKIVNAPKKVTISMNTKEDAGIQLVEAGDAATVITTARGDVYLLHKYICKKIAIKQINLRQVCVEGKMSDQGAYSRVTVLLLTNVGQLHIWQDTTNKLTRCVFGMVHQTLVTHMALTHDALYFTTKQGEAYIGTISRKTATPSQPIRKEKEKDGRSALVKFLEKDDCTSVRIVKIPNVHRAVSIAVDSEGLNFSILQSKPTCGLTSIPELSPSCFAKHMDSLRETAAEDDILHDVVFQVGTKRYPAHMFIVASSSEHLYKLYQDTITTPGEKPIIALTNVLPDVFERLLKFMYTGSCDVAELGPCSLKIRREDIVGKKEKDGDNEEEIENPMEISAFEVQKDKKRKNKRATETPRPIHPYCDPVKLVQAAAKRLHIMALHKLLDHFYYKDGKVCLKDSADYTKKAAMHWERESLHELVDTNVCTKDGALIPAHKCVLAARLEYFNGMFMHSWTESKLSTVTLPINYGILLPVINFLYTDSCPEIENCNESIDFICNMLIVADQLFISRLGEMCEIALANMITLKNCAELCQFAHTYNATQLKQCCMEFISINLSSILENRSLDPIEDALLDDITKYYCKFNPIMSSRVITPFFNAPNDDTIEEFTKNYPVDLDFIDEDVKRDDSILEIKKKKSKKVEYTDSEKARMRYESVSSVTSLDLSNEVSGDITLSLTKIKDEKEKSFEKKLKEKWTEVPSSQKQQKVVQARLKAISTAKDILNETPTETFTKLVKSSSINIPEAHITNSRMSVSPKESPTADLAMSPVFISHVGPKLSQKQRKKLALEGTEQSPRSMTDYFNKSVSPPEKKNPWKVIEAPVASSSPKAKPVQFNQILTDQRKQKEDFSRIMTKPLALTQLEDKAIEQLERFYNAHESDEEYIIVQRIQLQVSSPQWVHTANK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01429170;
- 90% Identity
- iTF_01529329;
- 80% Identity
- -