Basic Information

Insect: Wasmannia auropunctata
Gene Symbol: ZFX_2
Assembly: GCA_000956235.1
Location: NW:4862567-4919025[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0058 0.43 10.6 0.6 2 22 516 536 515 539 0.89

2 11 0.00054 0.039 13.9 0.1 2 23 554 576 553 576 0.97

3 11 0.19 14 5.9 0.7 1 23 595 619 595 619 0.92

4 11 0.022 1.6 8.8 0.3 1 21 665 685 665 686 0.95

5 11 0.00016 0.012 15.5 0.6 1 23 748 769 748 769 0.98

6 11 0.00064 0.047 13.6 0.1 1 21 775 795 775 796 0.96

7 11 7.6e-05 0.0055 16.5 4.9 1 23 813 835 813 835 0.98

8 11 0.0034 0.25 11.3 0.1 1 23 840 865 840 865 0.96

9 11 4.4e-05 0.0033 17.3 0.9 1 23 872 894 872 894 0.98

10 11 0.13 9.9 6.3 3.3 1 23 906 930 906 930 0.95

11 11 0.00034 0.025 14.5 1.2 1 21 936 956 936 961 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0058	0.43	10.6	0.6	2	22	516	536	515	539	0.89
2	11	0.00054	0.039	13.9	0.1	2	23	554	576	553	576	0.97
3	11	0.19	14	5.9	0.7	1	23	595	619	595	619	0.92
4	11	0.022	1.6	8.8	0.3	1	21	665	685	665	686	0.95
5	11	0.00016	0.012	15.5	0.6	1	23	748	769	748	769	0.98
6	11	0.00064	0.047	13.6	0.1	1	21	775	795	775	796	0.96
7	11	7.6e-05	0.0055	16.5	4.9	1	23	813	835	813	835	0.98
8	11	0.0034	0.25	11.3	0.1	1	23	840	865	840	865	0.96
9	11	4.4e-05	0.0033	17.3	0.9	1	23	872	894	872	894	0.98
10	11	0.13	9.9	6.3	3.3	1	23	906	930	906	930	0.95
11	11	0.00034	0.025	14.5	1.2	1	21	936	956	936	961	0.94

Sequence Information

Coding Sequence: ATGGAGAGCTatgaagaagacgacgacacCCATTTCTGCATCAAGTGTAACTTAACAATCCACGGACTCGACAATTATGTGCGGCACCGTCGATCAGGTTGCCGTCCGTCCGACGTTAAAATCGAGATCGCCCACGAGCCACCGTCGACTCCGACGACGGTGTCCTATCCCGAGATTCTGAACGCGGACGCGTTCTTCAGCTCGTTGGAGTTGCAGAGTAACGCTCGGCGAGCGCCCACTTTACTGGATAACAGAAAATTCAAGAAAGATGACAAGAGAAAGAAGGACCAGAAGGGTCAGGTGGACGGTGACGAGGCCGGCGCGAAGGATAAACTTCACAGCATGTTACCCGCTGTCAGCGATCTCGACGAACCGCCCGATCTGTGCATCCAGTCCCTCAAGCAGAACACCCTCGATCGTAAGAGGCACGAGAATCAGCAGAGTTGGTTGGAGGACGACACCATCCTCGCCGACCTTTCTTTGGGGAATAGCGCGAACAAGGAGCTGGCGAGATACGACTTCGAGTACGATGACTCCGAGGACGACATGCTGGAGGAGGAATTGGGGGAAGATTCCTATTCGGATTCGGATGACGGCGAAAACCGGGAGGGTCCGCCGCGGGATCACACCGGCGGAAAGTGGAAGCCCGGACTCGACGATTTGCCGCAGGACACGCCGCATATGCATGAGGAGGACGCGGAGCCCGACGACGATCATCAGGAACATCCCCCGCCGACGTATACTGGCGGCAAATGGCGACCCACAGAGACGTCACAAAAGGTCGAGGAATACGAAAGCAAGAACACATCCGGACAGCCGCCGCCAGGACACACACGAGGGAAATGGGTACCGGGTGCACGAACGGATATCGAGTCGGGATATTGGTGCAATCCTTGCGGCAGGAAGCTCGCCTCACGATTGGTCTACAACAGGCATCTGCTCTCTGATTTGCACGCCAGGAGGAGCATTAGGGAGCTCGACGGCGAAGCTCTCCATCTACGGCGTGGAATAAATTCGCACGCGAGAGTGTCCAGAAGAGTGTCCACTCGTAAGAAGACGTCACTTGCAATGAGAACGAAAGAGGAGCCCGAACAAAAGAAAGTTAAGAAAGGTCTGCGtcgaagagagaaggagatcCTCCTCTGCGAGATGTGCCGCACGCGCGTGAGGAGGCCTCAAATGGGTAAACATTTGCTCTCCCATTACCATTGCCGTGTGTCAGGTGTCCTCGTGAATCCTCGCAATCCAAGCGTACGCCGTTTCCTTCTGGAGCACATAGCGAACGTGGTCCGACAGAGCCCCTTCCAGTGCGCTCCTTGTCGTTTTTACTGCAACACCGAGGAGACGTTTCTGCTTCATTGGCGTTCCGATCTTCATTCCAAGACCGTAAAACAGATCGGCGGTAGTTGCCGATGCACTCCGTGCAACTTCTGGTGCGCAGACAACGCGACAATGGAGTCTCACCTCCTGAGTACGAGTCATCGTGACGTGGTATCGATGATGAAGGGCTCTGTGCCGGTAGTAATTAGTCGTCAACGTACGTTATCCTGCGGCAGTTGCGATCGGCAATTCCGATACAACTTCCAGCTGCGTTTGCACGCCAGGGAGACCGGTCACACCGCGAGCCACACCGCGTCGGACGTGTATCAGCAGCGTATCAAGTGCGATCTGTGCCCCCAAGTCCTCCGGTCGCTGGTCGCGCTTCAACGTCACCAGCTGACTAATCACGTCACCAAGGACAAGGAGAAGAGCGAGGTCGTGGTGGACGCGCGACCGACGCCGTACTTCTGCTCCTTCTGCTCGATGAACTTCATTACCGCCCAAGAAGCGGTGCTGCATCGAAGAACCTCTAGTCACAAGGAAACCGTGAAGGCGCGCAAGAGCGAGGAAGGTCTGTTGGACACGGAGCGAGATTGCCCTCACTGCGACCAGAAGCAGCCGAATCTTGCGGCGCACAAGAATCATCTGCTTCTTTGCCATTCGGAACTTTGCCACAgATGTCCACGATGTGGCACGCTTTTCGCCTTATCACAAGACGTCACTAGGCACACGCGAGAGGGTAATTGTCTCAAGAACGATAAGTCGGACGCGGGTGAAGCAGAGAGTGAGGAGAAAGAATGGAAATGCAAGGAATGCATCTTCTCCACGGATTCCAAAGCCGAATTCATTTTTCACGAGGCCCTGCATGCCGGTGCCGTTGAAGAAACGAATAAAGGCTCCGGTTCGAGCAAATTGCCGAAATATAAGTGCCCGACTTGTGCGAAGGCTTTCCCGAAAACATCGCTACGTAATCACATCAGGCAACATACCGGGGAGAAGCCCTTTCCCTGCATGAGATGTTCGATCTCATTCGCGAGGAGATCGCTTCTCATCATTCATCAGAGGCTGTGCAGCACTTCGTCGAAATCTCTGGACAAAACTGGCCGTCGGCGCAGCTTCATCTGTTCGCATTGCAAGGAAGGCTTCTACACAAAACATGCCCTTCGACAGCACATGCTGCGACACGCCGGTAAGAAGTACAAGTGCGGTCTTCCGGGTTGTCCAACGATACTTCGTACCGCAACCGAGCTGAAGACGCACCGCAGGTTGGTCCATGACAACATCGAGAAGCAGTATTCGTGTCCTGATTGCTCCTACGCCGCTAAAACGAAGACGCAATTGCGCAGGCACAGAATTCGGCACGAGGATTCCGCGAACGCCGAGAAGGTTCAAATCCATTCCTGCACCTACAAGGGCTGCAACTTCAAGACGAAGCTCGGCTCGAATCTGCGGAGACACGTGCGTCTGCACACGGGTGCCAAACCATACAAGTGTCGACATTGTCCCTACGCCAGTAACACCTTGGAAAATCTTCGGAAACACATACTGTCGACGAATCTGCATCCGGGTAAGACGATCTACGAGTGCGACTTTtgcaagaagaagaaggaaaaagagacgGATCCGTTCTGCACGAATTTCGCCAAGGAACTTCGTGCTCACTTACTGGAAGTTCACGCTGAAGACTTCCCGACACCAAATGATGCGAACAACTACACGAATAACATTTTTAGAccaaattaa
Protein Sequence: MESYEEDDDTHFCIKCNLTIHGLDNYVRHRRSGCRPSDVKIEIAHEPPSTPTTVSYPEILNADAFFSSLELQSNARRAPTLLDNRKFKKDDKRKKDQKGQVDGDEAGAKDKLHSMLPAVSDLDEPPDLCIQSLKQNTLDRKRHENQQSWLEDDTILADLSLGNSANKELARYDFEYDDSEDDMLEEELGEDSYSDSDDGENREGPPRDHTGGKWKPGLDDLPQDTPHMHEEDAEPDDDHQEHPPPTYTGGKWRPTETSQKVEEYESKNTSGQPPPGHTRGKWVPGARTDIESGYWCNPCGRKLASRLVYNRHLLSDLHARRSIRELDGEALHLRRGINSHARVSRRVSTRKKTSLAMRTKEEPEQKKVKKGLRRREKEILLCEMCRTRVRRPQMGKHLLSHYHCRVSGVLVNPRNPSVRRFLLEHIANVVRQSPFQCAPCRFYCNTEETFLLHWRSDLHSKTVKQIGGSCRCTPCNFWCADNATMESHLLSTSHRDVVSMMKGSVPVVISRQRTLSCGSCDRQFRYNFQLRLHARETGHTASHTASDVYQQRIKCDLCPQVLRSLVALQRHQLTNHVTKDKEKSEVVVDARPTPYFCSFCSMNFITAQEAVLHRRTSSHKETVKARKSEEGLLDTERDCPHCDQKQPNLAAHKNHLLLCHSELCHRCPRCGTLFALSQDVTRHTREGNCLKNDKSDAGEAESEEKEWKCKECIFSTDSKAEFIFHEALHAGAVEETNKGSGSSKLPKYKCPTCAKAFPKTSLRNHIRQHTGEKPFPCMRCSISFARRSLLIIHQRLCSTSSKSLDKTGRRRSFICSHCKEGFYTKHALRQHMLRHAGKKYKCGLPGCPTILRTATELKTHRRLVHDNIEKQYSCPDCSYAAKTKTQLRRHRIRHEDSANAEKVQIHSCTYKGCNFKTKLGSNLRRHVRLHTGAKPYKCRHCPYASNTLENLRKHILSTNLHPGKTIYECDFCKKKKEKETDPFCTNFAKELRAHLLEVHAEDFPTPNDANNYTNNIFRPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01423280;
90% Identity: iTF_00016937; iTF_01016111; iTF_01476529; iTF_00182241; iTF_00015665; iTF_00181587; iTF_01477180; iTF_01262072; iTF_00016285; iTF_00014991; iTF_01477915;
80% Identity: -