Basic Information

Insect: Volucella bombylans
Gene Symbol: rfx7.L
Assembly: GCA_949129095.1
Location: OX422140.1:318743678-318790738[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 7.9e-32 3.9e-27 97.0 0.0 3 78 274 349 272 350 0.97

2 3 2 9.8e+04 -3.8 0.1 23 37 681 695 678 700 0.77

3 3 2 9.8e+04 -3.7 0.0 21 41 1153 1173 1146 1176 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	7.9e-32	3.9e-27	97.0	0.0	3	78	274	349	272	350	0.97
2	3	2	9.8e+04	-3.8	0.1	23	37	681	695	678	700	0.77
3	3	2	9.8e+04	-3.7	0.0	21	41	1153	1173	1146	1176	0.79

Sequence Information

Coding Sequence: ATGTCCGAGAAAAATGTACACCAATTACAATGGAAACAAAAGAATCAGGATCAATCGATGTACGCCTCTCGAAGTGCTGGTATACAATCAACAACAGCGATTTCCAATCAATCAGCAGCATCTGCAGTTACCACCATATCAAATCATCCATCACATTCAGGAGCATTACTTGGAACACCTTCTAATGGTCGTTATCCGATAATTGTATCTGGTGGTAATCCACAGTCATCGGGGCCTCCTCCAGGTACATCGGGCACACCAGGTACACCAACATCATCATCTGCTTCGATTGgtcttcaacattttcatcatatgCATCAActtcagcaacaacagcagcatcaactatcacaacagcaacaacaacaccagcatcAACATCAGAGTCATCATCCTCCTCCACCACCTACTACTCATCAAACGAATGCACATTTTGAACTATCTAAAATGATGGCCAATTCGGGAGCTTTAACCAGAATGGAACTACCTCCGAGTTTGGGTAACCATCCCGTGTCGAGTGCGATAACAGAGAATGTCTTAAGTCTGATTGGAATGTCACCGTCCAGTGCAGGCAGTTCAAATAGAACTGGTGACAGTATTAAGATTCCAGATGAGGAAAAACTGcgaaaagttcaaaaatttgtGGAGTCTAATATCGGTGATCATGCGAGGCAGCAGATTTTACAAATCATTGACAGAATTTCAACATTAAAACCAGTTGAGCGATTACTTTTGTACCTACGGATGCCGGGAGAAACTCCGGAATCAGATCCTCTTAGACAGCCACAAAATCCTCTAGGAGCTCGATCTGAAATAAATCACACAATCAACTGGGTTCGCTCGCATTTGGAACATGATCCAAAGGTTTCCATCCCAAAGCAAGATGTTTACAACGATTACCTtttATATTGTGAGCGCTTGGATATAAAACCTTTGTCGAcagcagattttggaaaagtCATGAAGCAAGTGTTTCCTGAAATTCGCCCAAGACGTTTGGGAACACGTGGTCATTCAAGATATTGCTACGCGGCCATGCGAAAAACAACAAAGCTTACACCACCACAATTACCAATGCTAGGAGGGAAAAATGTAGATGTTGCCAATAGTGAAATAGAATGTGTCTCAGATGCAGAATCGTGGAACACTGTTCGGACATGGGCTGAAGGATTGTTGAATGCGAAATTTGATAGCATCAAAGATTTAGCTGAGCACATTGGTAAGAGTGATTATGTTGGTAGCGGAGCTGGTAGTTCTAGAGTTCTATTGCAGAAGAAACTTTTGCAAAGAGATGCGAAAGAAAAGCGAGTTTATGCTGATTCCGGACCGCTAAAGAAACGACGGAAGAAAAAACGTAAAGGTTCTACTTCCTCCGAATCAAGCACTACGCAGCAGACATCATCTGTGGGTTCACTAAATGACCCCTCACGATCATGTGATGACATTCTTATCGCCCCACACACAATtaaacaagaagttttagactcACCAAATTCACAGCCTCAAATACCAGTGGTAGCTCAAATGCATTTGCAGCATGCTACGGCGTCTTATGATGGGCAAATGCATAGCCATCAATTGCTTCCAATGAATTTAGCAACAGAGAACGAACGCACCAAGTCCTTAGGTCAACTACCAACAAACAGTCCAGTGGCAAAAAATCTTACAAAAGCAATTTCTGACCTTGCGCCGTTAGTAAACCTGTTGCCTATTGAACAGCAAACAGCACAACTAGCCTCTGTAAAAGAAGAGATAATTAACGATGAATACAATCCACAAAATGTGATATGCAAAAAGGTACGAAGGGCACATTTGACGAAAGGTATTTTAGCTACAAGCAACTCTTCTTCTTCAACAATCACCACATCAAGAGGGACTGCAATTGAAACTCCAACTGCGCCACCATCACTTACGCTATCACCTGCAGCTGTAAGCCACTACTCAATGGGACCTCCTGCACAGACAACAACCACAGCAATGGAAACAGCGAAAGTAGCCTCACAATTACGCGCCAAAAAATTGCGTTATTTACAGGCTCATTCTGAGATGTACCAAACCTATGATcagcaacaaaatcaacatcaaTCGCCTTTAGTGGATAATGTTGAGATAACAGAGGACAAAGATGTAGTGCCTGAAAACCTAGGTTTGCCGCGTGAGCGCGTTATAAGTATTTGTAATATGGACAAACATGAGTTAGATGATTATTTGAACGCAAACGACGAAGAGAACTCCCAAGATCAAGACGCTGAAttacttcaatattttcagaCGGGAGACGCTgagaacaacaataacaacaataaagaaacgcagctgcaacagcaacaacaacagcaccagcagcagcCAAATATAGATGCACCAAACCCAACGTTGACAGAGATGAACTCCAATTCGGCATTTGAAATACGAAATAAGAAGAAATCCATTGGTACAACAGGTAGCGGCTGTATTACGAAAGATCGTGATGACATAACACAGCTTCGTAATTATCTTCATCAAAATTTGGAGACAATTGGAGCATTAGCAGCAGGAGCTACAGTTCATCAAAAAGGAAATGTCCAGGTGGAGAAATGTCCGTCAAATGGAAACCATTATATCATGCCGGGCATATACAACGAAGGGTCAGCCTCAGCGTCTCTAACAATCATGTCTCAAAAGCATCTTAAACAAGCAGCATCGCCATCAGTTGCCATGGGTACTGCTGTAGTTGGAGCAGCATCTGTTACACATACAGTGGGACCACCCTCTACAACTAATATTGGCATTACTACttcaacagtagatccatcGGTTATAACACCTGATGAATATACAGCTGTTCCAAATAATGTGCGCGCAACACAGAAAAGAAAGATAAATCTTAATGCAATGGTACCTGCTTCAAATACAACACAACGGCGAAAGAACTGCACTTTCTTTCCAATATCGCCAAATATAAATCTTACCAATACTACTATAAACAGCACATTGACTTCATCTAGCACTACTTCCATGTCAGCTGCACCCAATATAAACCTTTTTGCTAGTCCAAGGCCGACAACTTTTTCAGTGCGAAATAAGCCAGTGCTACACAAACAACAATCGTTGCCAGCAGCAGACAAGAATGTTATTACATCCGCTAATGATCCAATGATTGGAGCTACTCGCAACAATAGAAACTACAATTCCATAACTTCGGCATCAGCACCACCCAGTCCCTCAATATTACAAGACACGATGATGCTTAGCAAAAGTTACGTCACTGTACCCGGCAATCCTATGGGTGGATACAATTCACTTCTATTGAATCACGACTACCAACATGAATTTGCAAACTCATGTGGAACAAACAAAATGCTGCCAAACGACCAAAATTCTTTAGAGTGTGTCTTAGACGAGCCTCCTTCACATTTGATGGCAGAATCGCGTTCAAGAAGTGTTCCACTTCAGTATTGCAATAGCCCTTCGTTTAATCAGACTACAAACTATCCTGGTTTCTTATCGACTTGCAGTTCAGCTGCACAAACTCCAGTGCCACCACATTTTGCCGATTTCAATGACACATCATCAATTTTAGATATTTTCAGTGATACCAGTCAAACGCATGGAACATCAATAAAACTGGAGGAATCTACTGGAAGTCTACTTTGCGGTTCAGTTGCTGATATTCTACCTCCAGAGAATGTAATTCCAGAATATGGTAGAATTCCGACTAATTTTGGTGGAATTGTCTCTAGATCAGTACCATCAACGCCTTTACCGCTGCAGAATGCTATTGATCCGTTTTTCGGTAGCAAAAATCATGAACAGAAACAAGACATCACCTCCAgtgcacaaaataaatattcaacgaAAATGTACGATATTTCCAAGTCAATGCCAACAACACCGATAACGTCAAACACAGCTACGCCATCGTTCCGCTACAGTCCGGAATTCAATCGTGATTTTCTAATCAACGGTAATACTGTGGAAAGCACCCCCGCCTATAGTCGAGCTCCATCTGTTGCAGCGGGCACAGCACCCAGTCTGACTGATTCATTACTTGACGATGGCAGAGAAGGTGAATCCAATTCACTAACCGATGGCATGGATGACTTAGGCAGCTTCGGTGAGGTATCCGAGGCAGACATTCTAAACATGAATAATCTTTGA
Protein Sequence: MSEKNVHQLQWKQKNQDQSMYASRSAGIQSTTAISNQSAASAVTTISNHPSHSGALLGTPSNGRYPIIVSGGNPQSSGPPPGTSGTPGTPTSSSASIGLQHFHHMHQLQQQQQHQLSQQQQQHQHQHQSHHPPPPPTTHQTNAHFELSKMMANSGALTRMELPPSLGNHPVSSAITENVLSLIGMSPSSAGSSNRTGDSIKIPDEEKLRKVQKFVESNIGDHARQQILQIIDRISTLKPVERLLLYLRMPGETPESDPLRQPQNPLGARSEINHTINWVRSHLEHDPKVSIPKQDVYNDYLLYCERLDIKPLSTADFGKVMKQVFPEIRPRRLGTRGHSRYCYAAMRKTTKLTPPQLPMLGGKNVDVANSEIECVSDAESWNTVRTWAEGLLNAKFDSIKDLAEHIGKSDYVGSGAGSSRVLLQKKLLQRDAKEKRVYADSGPLKKRRKKKRKGSTSSESSTTQQTSSVGSLNDPSRSCDDILIAPHTIKQEVLDSPNSQPQIPVVAQMHLQHATASYDGQMHSHQLLPMNLATENERTKSLGQLPTNSPVAKNLTKAISDLAPLVNLLPIEQQTAQLASVKEEIINDEYNPQNVICKKVRRAHLTKGILATSNSSSSTITTSRGTAIETPTAPPSLTLSPAAVSHYSMGPPAQTTTTAMETAKVASQLRAKKLRYLQAHSEMYQTYDQQQNQHQSPLVDNVEITEDKDVVPENLGLPRERVISICNMDKHELDDYLNANDEENSQDQDAELLQYFQTGDAENNNNNNKETQLQQQQQQHQQQPNIDAPNPTLTEMNSNSAFEIRNKKKSIGTTGSGCITKDRDDITQLRNYLHQNLETIGALAAGATVHQKGNVQVEKCPSNGNHYIMPGIYNEGSASASLTIMSQKHLKQAASPSVAMGTAVVGAASVTHTVGPPSTTNIGITTSTVDPSVITPDEYTAVPNNVRATQKRKINLNAMVPASNTTQRRKNCTFFPISPNINLTNTTINSTLTSSSTTSMSAAPNINLFASPRPTTFSVRNKPVLHKQQSLPAADKNVITSANDPMIGATRNNRNYNSITSASAPPSPSILQDTMMLSKSYVTVPGNPMGGYNSLLLNHDYQHEFANSCGTNKMLPNDQNSLECVLDEPPSHLMAESRSRSVPLQYCNSPSFNQTTNYPGFLSTCSSAAQTPVPPHFADFNDTSSILDIFSDTSQTHGTSIKLEESTGSLLCGSVADILPPENVIPEYGRIPTNFGGIVSRSVPSTPLPLQNAIDPFFGSKNHEQKQDITSSAQNKYSTKMYDISKSMPTTPITSNTATPSFRYSPEFNRDFLINGNTVESTPAYSRAPSVAAGTAPSLTDSLLDDGREGESNSLTDGMDDLGSFGEVSEADILNMNNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01522310; iTF_01521622;
90% Identity: iTF_01522310; iTF_01521622;
80% Identity: -