Vger005040.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Vespula germanica
Gene Symbol
BTBD2
Assembly
GCA_905340365.1
Location
HG996533.1:820246-822331[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.8e-28 7.7e-26 90.1 0.0 4 109 137 243 136 244 0.94
2 2 5.6 1.1e+03 -0.6 0.0 78 106 244 272 241 275 0.84

Sequence Information

Coding Sequence
ATGTCCACGGAAACGTCGTTGGGCGACATGCCGAATGTCGTCTCGAGGATACACAATTTACGATTGGGTCACGAGGATGGCGAGGAAGCCCATAATGGAAATAATGCTGCGGCCGATGAATCCGCGAATTCGGCGCAAAACGCTCAACCGATTGGGACTCTCTCTCGTGCTCGGCGTGCACTTAACTTTGTCTGGGACGAAGAACAGCCTACCACTTCTTCTACCTCGCGAGGCGTTGATATTTCATCGTCGAACGGTGATAAcAGGCCTCCAACTAATGCAGCTAATACAATCCACATCGATGGACATCCTCAGAATAATGTAGCATTGGAGAATAGCCACGGCTCCGCCGTGGCTACGTACAATTGGCAAGGTACGAAGGCTACGATGCGAGAGCGGATAGTTTTTCTATTTAACAACGAGATCCTGTCCGACGTGAGTTTCTTGGTAGGACGAGGAGCTCAACAACAGCGTATACCGGCTCACAAACTAGTCCTGTCTTCTGGAAGTGCCGTATTTTATGCGATGTTTAACGGAACGCTTGCTACAGCTTCTTCGGAAATAGAAGTACCTGATGTAGAACCTGCTGCTTTTTTGGCAgtgcttctttttttatataccgatGAGATACAAATAGATCCTGAAACTGTGATGACGACGTTGTATACTGCTAAGAAGTATGCCGTTTCTGCTTTAGAAAAGCACTGTGTCGATTTTTTGAAGAATAATTTAACCAGTGACAAtgcttttttacttttaacgcAAGCTCGTTTGTTCGATGAACCTCAATTAGCAGCGGTCTGCTTGGATACTATCGATAGATTTACGACAGAGGCCCTAAACGCGGATGGATTTGTAGATATTGATATCGATACGTTGATGGTTGTTCTGGAAAGAGATACGCTTCGAGTCAGGGAATCTAAAATATTTCAGGCTGTGTTAAGATGGTCAGAGGCAGAATGCGTGAGGCAGCAGCTGCCAGTTGTTCCAGAGAATCAACGTTTGGTTCTAGGCAATGCTCTTTCTTTAGTTCGTTTTCCTCTTATGTCCAAAGAGGAATTCACCGCGGGCCCGGCACAATCTGGATTACTAAATCATTCTGAGGTTCTatctttgttttgttatttcatACTGAACCCGAAACCAATGGTAAGCTTTCAAACGATGCCACGTTGTTGTATGACTGGCAAAGAACAGACCGTCTGTAGATTTCAGCATACCAAAAGTAAATGGGGTTACAATGGAACAAGTGATCGTATCAGATTTAGCGTGGATCGACGGATATTCCTTATCGGTTATGGAGTTTATGGCAGCATGCATGTACCCGCGATATACGAGGTATTAGTGGAGCTAATACATACGGCATCAGGGAAAGTAATCGCTTCGAATTCAACGACATTCAGTTGTGACGGTTCAAAGTATACTTATATTCTAATGTTTAAAGATTTAGCCGAAATTTTACCAAACACTATTTATACGGCATCTGCAACATTTAAGGGTCCCTATTCTCATTACGGAACGAAAGGTGTAAAAACAGTATTGGTCGATTGCGATTCCGGAAATGGAAaagtaaaatttgattttaatatcgaatctGGTGATAATAATGGAACTTCCGTCGAGGAAGGACAAATTCCTGAGCTTATCTTTTACACTTAA
Protein Sequence
MSTETSLGDMPNVVSRIHNLRLGHEDGEEAHNGNNAAADESANSAQNAQPIGTLSRARRALNFVWDEEQPTTSSTSRGVDISSSNGDNRPPTNAANTIHIDGHPQNNVALENSHGSAVATYNWQGTKATMRERIVFLFNNEILSDVSFLVGRGAQQQRIPAHKLVLSSGSAVFYAMFNGTLATASSEIEVPDVEPAAFLAVLLFLYTDEIQIDPETVMTTLYTAKKYAVSALEKHCVDFLKNNLTSDNAFLLLTQARLFDEPQLAAVCLDTIDRFTTEALNADGFVDIDIDTLMVVLERDTLRVRESKIFQAVLRWSEAECVRQQLPVVPENQRLVLGNALSLVRFPLMSKEEFTAGPAQSGLLNHSEVLSLFCYFILNPKPMVSFQTMPRCCMTGKEQTVCRFQHTKSKWGYNGTSDRIRFSVDRRIFLIGYGVYGSMHVPAIYEVLVELIHTASGKVIASNSTTFSCDGSKYTYILMFKDLAEILPNTIYTASATFKGPYSHYGTKGVKTVLVDCDSGNGKVKFDFNIESGDNNGTSVEEGQIPELIFYT*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01235107; iTF_01512262; iTF_01512906; iTF_01233742; iTF_01514903; iTF_01232472; iTF_01233084; iTF_01234428; iTF_01090078; iTF_01514240; iTF_01454280; iTF_00738468; iTF_00754865; iTF_00393687; iTF_01255786; iTF_00873879; iTF_00024705; iTF_00224641; iTF_00864065; iTF_01068385; iTF_00227362; iTF_00140675; iTF_00306371; iTF_00761059; iTF_00216485; iTF_00219205; iTF_00233317; iTF_00866789; iTF_00982373; iTF_00221990; iTF_00230118; iTF_00088135; iTF_00221351; iTF_00232071; iTF_00962599; iTF_01419079; iTF_00215112; iTF_00734024; iTF_01069064; iTF_00183369; iTF_00860489; iTF_00983049; iTF_01419721; iTF_00086410; iTF_00217162; iTF_00217834; iTF_00862667; iTF_01122539; iTF_01123147; iTF_00219884; iTF_01066348; iTF_00231405; iTF_00084654; iTF_00214478; iTF_00225326; iTF_00232686; iTF_00861262; iTF_00865422; iTF_00118095; iTF_00142543; iTF_01539695; iTF_01424464; iTF_00141297; iTF_00230769; iTF_00963282; iTF_01067698; iTF_00215795; iTF_00218515; iTF_00223283; iTF_00762643; iTF_01070451; iTF_00226004; iTF_00684244; iTF_01071092; iTF_01421012; iTF_00222613; iTF_00964565; iTF_01067029; iTF_00141911; iTF_00866103; iTF_00966104; iTF_00087289; iTF_00184025; iTF_00228057; iTF_00963929; iTF_00228762; iTF_01065659; iTF_00864732; iTF_00961916; iTF_00085501; iTF_00226685; iTF_01069757; iTF_00229438; iTF_01417790; iTF_01420350; iTF_01498302; iTF_00088927; iTF_00220671; iTF_00223967; iTF_00863359; iTF_01418431; iTF_00861984; iTF_00763330; iTF_00360305; iTF_00360995; iTF_00625589; iTF_00676118; iTF_00773912;
90% Identity
iTF_01090078;
80% Identity
iTF_01514240;