Mgen003085.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megalopta genalis
Gene Symbol
BTBD2
Assembly
GCA_011865705.1
Location
NW:337613-340128[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.1e-27 1.1e-24 85.8 0.0 4 109 159 265 158 266 0.94
2 2 6.3 1.1e+03 -1.1 0.0 79 106 267 294 264 297 0.83

Sequence Information

Coding Sequence
ATGAAACGGGGCAGTACGTCGAGAAATATTACGTCATGCTTGAAAATGTCCTCAGAGACTTCCCGGAATGATGTGCCAAATGTCGTATCGAGACTGCATAATTTGCGCTTAAGTCAGGAAGATGGAGATGATCCCCAACCAAATGCAAGTGTAAATCATGTTGCATCTGGAGACTCGTCTCCAGAGACTATTCGAAATACCCAACCGATTGGTAATGTCACACTCTCACGGGCTAGACGTGCACTTAATTTTGTTTACGATGAAGATCAACCAACAACCTCTATGGCTAGAAGCGGGGAATCTTCATTTTCTAATGGAGATAATAGACCTCCGACAAATGCAGCAAATACATTGCATTTAGAGGGACGACCTCAGAGTAATGTTGCCTTGGAAAATGCATCCACGAATAGTCAAACTACTGTTGCATATAATTGGCAGGGTACAAAAGCTACAATGCGTGAAAGGATTGTCTTTCtgtttaataatgaaatattgtcTGATGTGAGCTTCATAGTGGGGAGAGGAGCACAAAAACAGCGTATACCAGCTCATAAACTAGTCCTATCTTCTGGAAGTGCTGTTTTTGATGCAATGTTCAATGGAACACTTGCTACAACTTCTTCAGAAATAGAAGTACCTGATGTAGAACCAGTTGCTTTTTTAGCAgtgcttctttttttatacactgataaaatagaaatagatcctGAGAGTGTGATGATGACGTTATATACAGCTAAGAAGTATGCAGTATCAGCTTTAGAGAAGCACTGTGTTGAATATCTAAAGAGTAATTTAACCAGTGATAATGCTTTCTTACTCTTAACGCAAGCTCGTTTATTCGATGAGCCTCAACTGGCTGCAGTCTGTTTGAATACCATAGATAGATTTACTACCGAAGCATTAAATGCAGATGGTTTTACAGATATAGATATTGATACACTGAAGATTGTTTTGGAGAGAGATACTCTTCGTGTTAGAgaatctaaaatatttcaagCAGTTCTAAGATGGTCAGAGGCGGAATGTGTAAGACACCAGCTACCCCTAACTCCAGAAAATCAACGTTTTGTGTTGGGTAGTGCTTTCTCATTGATTCGTTTTCCTCTAATGTctaaagaagaatttactgctgGTGCAGCACAATCTGGACTTTTGAATTATGCAGAGGTTCTTTccttattttcatattttatactaaatccAAAACCAGTAGTTGGATTTCAAACAATGCCTCGTTGTTGTATGACTGGTAAGGAACAAACTGTATGTAGGTTTCAACATACTAAAAGCAGATGGGGATATTATGGAACAAGCGATCGCATTAGatttagcGTTGATAGACGAATATTTCTTATTGGCTATGGAGTTTATGGTAGTACGCATGGCCCTGCAATATATGAagtattaatagaattaatacaTACTGCTTCTGGGAAAGTAATTGCTACAAATTCATCAAGTTTTAGCTGTGATGGTTCAACATACACTTATCGCCTAATGTTCAAAGAATTAGCAGAGATTTTACCAGATACAATTTATACAGCATCAGCAACATTTCAGGGTCCTTGTTCTCATTATGGAACTAAGGGTTTAGAAACTGTTATGGTAGATAGTGATACAGGAAATGGAAAAGTCAAGTTTGAATTTAGTATTGAGACAGGTGATAATAATGGAACGTCTACAGAGGAAGGACAAATTCCTGAGCTTATATTTTACACTTAA
Protein Sequence
MKRGSTSRNITSCLKMSSETSRNDVPNVVSRLHNLRLSQEDGDDPQPNASVNHVASGDSSPETIRNTQPIGNVTLSRARRALNFVYDEDQPTTSMARSGESSFSNGDNRPPTNAANTLHLEGRPQSNVALENASTNSQTTVAYNWQGTKATMRERIVFLFNNEILSDVSFIVGRGAQKQRIPAHKLVLSSGSAVFDAMFNGTLATTSSEIEVPDVEPVAFLAVLLFLYTDKIEIDPESVMMTLYTAKKYAVSALEKHCVEYLKSNLTSDNAFLLLTQARLFDEPQLAAVCLNTIDRFTTEALNADGFTDIDIDTLKIVLERDTLRVRESKIFQAVLRWSEAECVRHQLPLTPENQRFVLGSAFSLIRFPLMSKEEFTAGAAQSGLLNYAEVLSLFSYFILNPKPVVGFQTMPRCCMTGKEQTVCRFQHTKSRWGYYGTSDRIRFSVDRRIFLIGYGVYGSTHGPAIYEVLIELIHTASGKVIATNSSSFSCDGSTYTYRLMFKELAEILPDTIYTASATFQGPCSHYGTKGLETVMVDSDTGNGKVKFEFSIETGDNNGTSTEEGQIPELIFYT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01513562;
90% Identity
iTF_00024705; iTF_00864065; iTF_00866789; iTF_00183369; iTF_00860489; iTF_00862667; iTF_00861262; iTF_00865422; iTF_00762643; iTF_00866103; iTF_00184025; iTF_00863359; iTF_00861984; iTF_00763330; iTF_00625589;
80% Identity
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