Basic Information

Gene Symbol
ZNF236
Assembly
GCA_014083535.1
Location
JACHAV010000010.1:5494112-5508512[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 5.8e-05 0.0041 17.0 1.0 2 23 168 189 167 189 0.96
2 26 0.00029 0.021 14.8 1.1 1 23 195 217 195 217 0.98
3 26 5.7e-06 0.00041 20.1 0.3 2 23 223 244 223 244 0.97
4 26 0.018 1.3 9.1 0.1 3 23 252 272 250 272 0.96
5 26 0.00012 0.0088 16.0 0.6 2 23 283 304 283 304 0.98
6 26 0.015 1.1 9.4 0.3 8 23 306 321 305 321 0.96
7 26 1e-05 0.00072 19.4 0.6 1 20 327 346 327 349 0.96
8 26 1.7e-05 0.0012 18.7 0.6 1 23 355 378 355 378 0.95
9 26 3.2 2.3e+02 2.1 0.9 3 17 389 403 387 404 0.91
10 26 1.6e-06 0.00011 21.9 1.9 1 23 506 528 506 528 0.98
11 26 0.00011 0.0079 16.1 1.7 1 23 534 556 534 556 0.99
12 26 0.02 1.4 9.0 4.2 1 23 562 584 562 584 0.97
13 26 1.9e-06 0.00014 21.6 2.6 1 23 588 610 588 610 0.98
14 26 0.0052 0.37 10.8 9.0 1 23 665 687 665 687 0.98
15 26 7.6e-06 0.00055 19.8 4.0 1 23 693 715 693 715 0.99
16 26 7.5e-06 0.00054 19.8 2.2 1 23 721 743 721 743 0.98
17 26 8.2e-05 0.0059 16.5 7.2 1 23 749 771 749 771 0.98
18 26 0.028 2 8.5 1.0 2 23 1147 1168 1146 1168 0.96
19 26 0.00017 0.012 15.5 2.8 1 23 1174 1196 1174 1196 0.98
20 26 6.8e-05 0.0049 16.8 0.6 2 23 1203 1224 1202 1224 0.96
21 26 2.4e-08 1.8e-06 27.6 1.4 2 23 1322 1343 1321 1343 0.98
22 26 0.0002 0.014 15.3 5.0 1 23 1349 1371 1349 1371 0.99
23 26 0.00028 0.02 14.8 3.2 1 23 1394 1416 1394 1416 0.98
24 26 3e-05 0.0022 17.9 0.3 3 23 1637 1657 1636 1657 0.98
25 26 2.8e-05 0.0021 18.0 3.6 1 23 1663 1685 1663 1685 0.98
26 26 0.0018 0.13 12.3 3.8 1 23 1691 1714 1691 1714 0.94

Sequence Information

Coding Sequence
ATGTTGACAGAACAAATTGTAGTTTCTGAATCATCTACTGGCGATACATTACCATTAGGATTTATAACTGCTGAAGATGGTCGAACTCTTTTAGCAGTAGCAgAACACGAAGATGGTATCGTAGCAATTATGTCAGCACCTGTAGCATTTATGCAgcagaataatataatttcaccATCATTAGTTAAGACTATAGATGGAAATATGATCGTGCATCCTcctatttttcaaataagtaTAGAAGGGATTGCTGGAATTCAACAAGGTGCTATATTACCAATACAAACATTAGAAGCAGTTCCTACTGTTATGGAAGATGTATCAAGTTGTGTACAGTCTATAGTTCCTACGTCAACAGATTTAGcaataaataacaaagaacaaaaattttcttccgaGTTCCATATAACACAACTTCCTGTtcagaaaaataatactaaacgTAATCCCGGCAGACctaggaaaaatgaaatcatctCATCTCACAGTATAGAtgatatgaaatgcaatatctGTGGGCAAGACTTTGATAAACAATCTCTATATCGGAAACATATGGATCAACATGCAGAGGAGAAACCGCATCGTTGTCCAAAGTGTTCTGCATCCTTTAATATTCCgACGAATTTCACGCTTCACATGGCAACGCATAATACTGGTGAACCAAAATGTCCCGAATGTGGTAGAAAATTTGCTAGAATGGCCAGTTTAAAATCTCACATGTTGTTGCatgttaaagaagaaaatcttttttgtaCGGAGTGCGAAGATGCCTTTCCAACGAAAgcCCAATTGGACGCACACTTGAAGTTACATGGTGAAAAATCATTAACGGAGGAAGTGCGAAAGTGTAAGCTTTgcaataaacaatttgttcaGCCTGCTTTATATAGACTTCATATTCGTGAACATTATAAGTCGTTTCAAAAACCTAGTCAGCTAATGCGTCATATTAGAGTTCATACAGGAGAGAAGCCTTTTAAAtGTACCGTATGTAATCGCGCATTTACTCAGAAAGGTTCTTTACAAATTCATATGTGGCAACATGATGGTATCAGACCTCATATTTGTACTCTTTGCAATGCTAGATTCAGTCAGAaaggaAATCTAAATGCCCACATTTTAAGGGTACACAGTGCTCCAGAAGGAGAATCCATTTATGGATGTAGTTATTGTCcttgtatttttaaaaagcttGGCAGTCTTAATGAGGCTGATATGCGAGCTACAGTTGATAGTGTCATATCACAGCTAGCATCCTTGGAATCTGGAATTGCTAATGTAGCAAATTCTACTCAATCTGAAACTACGactgaaaatagaaatgatattttacaGGAAGCATTAAATAATAGTGGATTGCctagtaaagagaaaaatctttctaatgAAACAATGGACTCGAAAAAAGTAGAAGCAAAAACAACATATGTTACGTTGTTGGATAGAGCCCCTGACGGCACAATGagaaaatatttaacaataaagcAGCGATGTATAGGAAATATACGATGGTATGCATGTTCTTTCTGTCacaaagaatttaaaaaaccATCGGATTTAATACGTCATTTAAGAGTACATACTCAAGAAAAACCATTTAAGtgTTCTTATTGCTTTCGCTCGTTTGCATTAAAATCAACGATGATTGCACACGAACGTACTCACACTGGTACAAAGAAGTATGCCTGTGGTTCGTGCGATAAAACGTTCGCGTGTCATAGTAGTCTTACCACTCATACGAGATTACATACAAAACCGCACAAATGCACTGTATGTGATAAATCATTTAGTTCTAGCGCTGTTTTAAAAAGTCACATGAAAAGTCATTCAAAAGGAAAATCAAATATCTCGCCAGAAGCAGAAAGTTTAGTTCCACAAATCATTTTACAGGAACCATTAGTTATTAGCGATGCGGGTAATAAGATCAGCGTGGCGCATGTACaatcaaaacaaaaacatGTTTATGACAGTGCAGATGTTGCAAGACCACACAAATGTTGGATATGTCATGCAGCATTTAGGAAAATTAGTCATTTAAAGCAACACCATCGTCGGCATACTGGAGAACGTCCTTTTAAATGTCCTAAGTGCGATAGAAGATTTACGTCTAATAGCGTTCTCAAGTCACATTTGCATACACACGATGATGCAAGACCATACAGTTGTACTGTATGTAACACTAAGTTTTCTACACAAAGCAGTATGAAGAGACATTTGGTTACTCATAGTAACAAAAGACCATTCATGTGTCCTTATTGTCATAAAACATTCAAAACTTCTGTTAATTGTAGAAAACATATGAAGATACATAAACATGAACTTGCACAAAGACAATTAGAACAacagaaaaaacaacaacaaattaAGGATGTACCAAAGACATTAAATAAGGATAAGGGAACTATTTTACCAGAGAATATAGCACTGTCAGAGGAAATGGAAGTATCATTCCAACCGCAAATGGCACCCGATTTTGCATTAGCTTTTTCTGatcaatttcaaaatataacggaaaaagaaaaaacatttttaacaaCAGACAGAACACAACCGGttattaattcaaatttatctaCAAATTTACCTAcaatagaaacaaataatttaccAACATCACAAACTTTAAATACCGACGAAACAGCCACTATTACAATTCCTAATTATACAGGGGATCAATCACTTACGCCTGAAAGTATACGTGAGATAGAAGAAACTTTCAATCAACAATTGTTTAATATTGGAATGAATCTTGGTTTGGGAAATAATCTCCCAAGACCTATAGATGATACAAACACAAATACTCTTGAACAAAGGGAACAAcctgtattaaatattatttatgataataataaaaatttagagTCATCCGCAAATACAATGTTCACATCACAATTTGACTCATTTGATATTAGTCAGATTACATTACAACCTGATACTGAAATAGACATTGGACTCAATACAGAAAATTCTGAAAATATGGCAAATATTTTAACTAGATCTATACAAGAGAGACAAGAAATAAATACTATcactattgaaaataatacaaatgacAATCATATTAAAACACCAAAACAATTAATGATATTAGGACCCAAACAAACTGGATCTGAAACTGCTGTAAAACTGCCACAGTCTTGTCCAAGGTATCCAAAAGTTATAGCTAAAGCAGATACAACAGATACAACAGATATCGAAATCATGAATTTAACAAATAGTACAGaaatacaaatgataaatgatagtaataaaaaacatCAAGAAAACATCGTATGTCACGAACATGGAAATAATACTTTACATTTAAAatGTGATTTAAACAacgaaaattttcaagataCACTACAATTAAATGCTCATTCAAAGTTACATTCCCCGTCAAACATCATTTATACAGATATTAATGGATGTAGCAGTCAATGTGATTCTTTACTTCAGTGTCATATATGCAGTGAACAAGGCTTTACTACAGAAGAATTAAagGAACATTTGCAAACTCACCGCGGAATAAAGGGCTTCCAATGTACAGAATGTTCTCTTAAGTTCTGTACTAGTGGTGGACTTAGTAGAcatttaaaattacataaaagtAAAGAacAATGGAAGTGTACAATCTGTCAACAAGTTTTTATTAGCAAAGcccaattgaaatctcataaCAAAATACATGATAATAGCCTTAATGCAAGCTCGTTAGAATCAGATAAGTtgcagaaagaaaatatttctattaataaaactaTGTCTATTGATTCTacttcaaataataaaatttcttttgatagTAAAACTCTATCAAATAAATCTGTCAAATTAGATGACAAGATttctttaaatgataaaatgggTAATGATTCGTCAGTGTCAGAAAAAGTTCTTTTAGATACAGTAgcagaaaaaaagatcatggATCAAATAGATGGTAgtgcagaaaaaaaagaaacaaaacagtatatcaataaatgtaaatactgTCCGAAAACATTTCGCAAACCAAGCGATCTTATAAGACATATTCGGACGCATACTGGCGAACGACCGTACAAGTGCGATCATTGCAGTAAAAGCTTTGCAGTGAAATGTACATTGGATTCTCATATGAAAGTTCATAGCGGCAAGAAGACGTTTTGTTGTCATGTTTGCAATAGTCTATTTGCTACAAAGGGTTCTAAACCATTTAGATGTTCGATTTGTGATTTAAGATTTCGAACTTCTGGTCACAGGAAAGTACATTTATTGAAACATGTGAGACAGCACAAAGGTACTActaaacgaaaacaaaagcaCATGAAAGTTTCAGCTGTAACTGAGGCAACCCTTGATTTAGAAAAGTCGATTGAAGGTGTAGTCCATTTAGTAACAACTGATAATGATGTATCTACATCATCAAATGTTGATTACTCAAACCTTGACACAATTAGCATTGAAACTAATAACTTAGTCAATcagattaatttgaataacgATGCAAtgatattgaataataattcaattgtgTCATTAAATGAGAATAATCAATTAGTAGCAAATTTGCATTTCTTATTAGCAAATGGATTTGTTACCATTCAAACGGATGATACTTCACCATCACCAACAACAGCTACggcagcaccaccaccactagtACCTATTTCTGATGCAAATATTATTCAGAATGAGACTAAATTACCAGAATTTGTTAATACTGCACCTATACAGGAATCTTATATTGACACAGGTACTAAACACGTTGTTATTACAAATGAAACATCAACAAGAGGAGCCCTTCCAACTACTCATGTTTCAACAGATTCAAATAATGATATGAGTATAACACAGTTAGAATATACAAATGCTACAACAAATAAAACACAAGAAACAATAAAGAAGCAAACAAATAAGAGCAATTCATCAAAACAGAGAGCATGTGATATTTGTGGAAAAACATTTATGAAGCCATATCAAGTAGAGAGACACAAACGAATTCACACAGGTGAACGTCCATTTAAGTGCGAATTATGTACAAAATCATTTGCTCAAAAGGCAACATTACAAATGCATCAAAAACATCATACAGGTGATCGACCACATGCTTGCCCATGCTGCGAATTTACTTTTTCACAAAGAGGAAATTTACGAACACATTTAAGACGTGTTCATCGATTGGATCTTATCAGTGCTAAAAAGTTGAAAACAAGTCAACAAGTTTTAAGTGCTAAactaatacaaaataatataggTGAAACAAAGATTCTAAGTTTAGATGATATTGCCTTTGTCCAGTTtgtaaaataa
Protein Sequence
MLTEQIVVSESSTGDTLPLGFITAEDGRTLLAVAEHEDGIVAIMSAPVAFMQQNNIISPSLVKTIDGNMIVHPPIFQISIEGIAGIQQGAILPIQTLEAVPTVMEDVSSCVQSIVPTSTDLAINNKEQKFSSEFHITQLPVQKNNTKRNPGRPRKNEIISSHSIDDMKCNICGQDFDKQSLYRKHMDQHAEEKPHRCPKCSASFNIPTNFTLHMATHNTGEPKCPECGRKFARMASLKSHMLLHVKEENLFCTECEDAFPTKAQLDAHLKLHGEKSLTEEVRKCKLCNKQFVQPALYRLHIREHYKSFQKPSQLMRHIRVHTGEKPFKCTVCNRAFTQKGSLQIHMWQHDGIRPHICTLCNARFSQKGNLNAHILRVHSAPEGESIYGCSYCPCIFKKLGSLNEADMRATVDSVISQLASLESGIANVANSTQSETTTENRNDILQEALNNSGLPSKEKNLSNETMDSKKVEAKTTYVTLLDRAPDGTMRKYLTIKQRCIGNIRWYACSFCHKEFKKPSDLIRHLRVHTQEKPFKCSYCFRSFALKSTMIAHERTHTGTKKYACGSCDKTFACHSSLTTHTRLHTKPHKCTVCDKSFSSSAVLKSHMKSHSKGKSNISPEAESLVPQIILQEPLVISDAGNKISVAHVQSKQKHVYDSADVARPHKCWICHAAFRKISHLKQHHRRHTGERPFKCPKCDRRFTSNSVLKSHLHTHDDARPYSCTVCNTKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTSVNCRKHMKIHKHELAQRQLEQQKKQQQIKDVPKTLNKDKGTILPENIALSEEMEVSFQPQMAPDFALAFSDQFQNITEKEKTFLTTDRTQPVINSNLSTNLPTIETNNLPTSQTLNTDETATITIPNYTGDQSLTPESIREIEETFNQQLFNIGMNLGLGNNLPRPIDDTNTNTLEQREQPVLNIIYDNNKNLESSANTMFTSQFDSFDISQITLQPDTEIDIGLNTENSENMANILTRSIQERQEINTITIENNTNDNHIKTPKQLMILGPKQTGSETAVKLPQSCPRYPKVIAKADTTDTTDIEIMNLTNSTEIQMINDSNKKHQENIVCHEHGNNTLHLKCDLNNENFQDTLQLNAHSKLHSPSNIIYTDINGCSSQCDSLLQCHICSEQGFTTEELKEHLQTHRGIKGFQCTECSLKFCTSGGLSRHLKLHKSKEQWKCTICQQVFISKAQLKSHNKIHDNSLNASSLESDKLQKENISINKTMSIDSTSNNKISFDSKTLSNKSVKLDDKISLNDKMGNDSSVSEKVLLDTVAEKKIMDQIDGSAEKKETKQYINKCKYCPKTFRKPSDLIRHIRTHTGERPYKCDHCSKSFAVKCTLDSHMKVHSGKKTFCCHVCNSLFATKGSKPFRCSICDLRFRTSGHRKVHLLKHVRQHKGTTKRKQKHMKVSAVTEATLDLEKSIEGVVHLVTTDNDVSTSSNVDYSNLDTISIETNNLVNQINLNNDAMILNNNSIVSLNENNQLVANLHFLLANGFVTIQTDDTSPSPTTATAAPPPLVPISDANIIQNETKLPEFVNTAPIQESYIDTGTKHVVITNETSTRGALPTTHVSTDSNNDMSITQLEYTNATTNKTQETIKKQTNKSNSSKQRACDICGKTFMKPYQVERHKRIHTGERPFKCELCTKSFAQKATLQMHQKHHTGDRPHACPCCEFTFSQRGNLRTHLRRVHRLDLISAKKLKTSQQVLSAKLIQNNIGETKILSLDDIAFVQFVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01513614;
80% Identity
-