Basic Information

Insect: Tyria jacobaeae
Gene Symbol: baz-2
Assembly: GCA_947561695.1
Location: OX387234.1:3236018-3254928[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.5e-11 1.1e-07 31.9 0.0 2 75 624 700 623 702 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.5e-11	1.1e-07	31.9	0.0	2	75	624	700	623	702	0.85

Sequence Information

Coding Sequence: ATGACTCACCACTACAGTGGGGCTACGGTCTATACGGTCTACGCGTACTGGGGTCGCGATGGAGGCGCCGGCGGCGGAGGCGGCAGTGCGGCGGCGGCGGCGCAAGCGCAGGCGGCGCTCTTCGGCTTCGGGAGCCGGTACCCTCCGCCCACCACGCTGGGCGTCGCTGCCAACCAAGCAGCGTCACTTGGCTTGCACCCTGCTGCCAGTGCTGCCTGGTGGTCAATGGCGTCTCACCTGGCCGCTCAAGACTACTTAGCCCGTCTCCAAGCGTCAGGTCTAAACTTCCCACCGCTAGCAGACCCGTATGCTGCATTATCAGCCCTGTCAGGAGCTGGGTTGAAGCAGCCTTCAAAACCTGGGAAAATGTCTTCGTCTAGGAATGAGAGGTCAGGTAGAAGCAGTACGTCATCCAGCGCATCGGCCAAGGATAAGAGTCCATCAACCAGCTCCAATTCTCAAAATATGAGAGCGCAATACGGTCTTCCAAAGACGTCATCACCATCGGCAATGCATTCACATTCCCAGTCGCTGTCAAGCCTCGCCTCTCTCAACAGTCTGGTGTCTGGTCCACATCAAAGCAAACCTAGCAAACCCAATGCACCCCCACCTTCAAAAAAGCCATCTTCATCCGGTATCGGAAGCTCTAAAGGCAAGGAGCGAGAGTTGGCGCTGCTACGCGGCGATCTGATGCTGGCGCAGGCCGCAGCACACGGCGCCTACCACGCTGCTGTCGCTGCAGCTGCTAAGGGGAAGAATATGTCACCCCTGTACCCGTTCGGCATGCCTGGTTCCGATAAGGATCGACACACCGGTATTGACTCACTCACAGGGCTCCCCCACACTATTCTAAGTGCTGCATTAGAAGGAGGTGACCCGTCGTCAGTGCTCGGTGGAGTTCGTTTACCTCCGGACACAGAAATTATAAAGTATACGTCATCATTAGCGGGACCCAAGGGAGGAGCAGGTGGCACGACCCGAGGTCGCAAGAAAACAATATCTCTGGACCCCCCGCACGTCAGCCTGCACCCCGCCGCAGAGAGACCTGACCGGACAACACCTTTGCCTAGCAAACGACCTAAACTGGACGAGTACGGCAATTCCCGGTCGTCAGTGGAAGTGATCCGCCTCCCGAACAAACCTGACCGCACCGGGACCAACTCGTTGTCCGGCACGCCGCCACCTAATCTATCTGATTATGCAGGTATATCTCGCGAACTGCTACAAACGATAGCGAGTCAGAGCGGCGTGAGTTTAGCCGCGCTCGAGCGACAGCTGGCGGGCTCCAGCACCTCTGGAGACTACAGGACTGCAGCAGATTCAGGTCTCAACCTAAGCACAAAGATAGGCTCCGAATCTCCTATGGGCCTGGGCATGAAGATGGGAGCTGATGATGATGCGCCCCTCAACCTCTCACTCAAGCCTACCCCGGCAAGTTCACAAGCATCAGATGCTTTGTCCCGATTAACATCGTTGAGCAGTTCCCTCAACGCCTCCTCAAGTCATGACAGAATATCCCGTCGTAAGCCGGGCGTGCGGCCGCGCCGGGCCGGCCCCGAGGCGGGCGAGTCGCCGCGCCCCAAGTCCAGCGGTAGTGAGGACAGTGAATCTGTGGCTGGTTGGGCAGGTCGTGAAGGCAGACCCCGAAACCTCGGCCGGGGGGTAAGCAAGCCCAAGAAGAACACCGTCGCCTCCCTCCTGGCCCAAAGTCGGGCTCTAGGTCTTCGACCTGCTCTAGCTCACCAACTACTGGCTGAAACTGATTTGGAAAAACTCAAAGCTCTGTTAGGAGAGACAGCGAGTACCGACTCCGAGTGTCCATCTGATAGTTGTCCGTCCGATTCTGATGCGAGCGACACCAGTCGACGGACCAACGACGCTCAATTGAGACTGCCATTGGCGTTAGGTTGGAAGCGAGTTACAGTAATTAAAGGTCTATCCCGTAACTGTAGTATCAAGGGTGACGTCACATACTCGCCGCCCGAACCTCACGCCGCCGTTAGCGTTCGTTCGATGCAAGAACTACAAAATTTCCTGGACTTAAACCCATCGCCTCCGTTGTCTACGGATAACTTCAGCTTCAGCGCTCGCACGGTGCTCGGCGAATACGTACAGCCCGCCTCTGATGTTGGCGAGCCGCTCATATACAACGAAAATGAAATTAATAAGAGGTTGGAGGAGGCCCGCGCCCTGTCGGGCGGGCGGCCGACGCCTCCGCCGCTGGACAGGCGCATGGAGCTGGCGCGGCTGCAGCAGGCCGCCCGAGACGCCAGGAGAGACGCCAGCGCCAGGTCTCGAGACCAGGCACGTCTAGAACGTTCAGAAAAAGCAGAACTGGCCAAGCGTGAGAAGGAAGTGCGCAGTCAACAACTTCTAGAGCATATCAACAAGAACCGTACGCAGTTGACCATCGAGCCGCTGCCCACGATTCCCAAAAGTGTAATCGACGAGTGGAAAACACCTGAGATAGTAATGGGACCTGCCACTAAGAGTAACAAGGATCGCATTATGCCTCCTATAAGCCTCTCTCTCATACCAGTTTCAGGCCCAAAAGATTCTCAACATTCTCCTATAAAGACAATAAAATATGATCAATCTGGTTGGAAAGAGGAAATCGAAGAATATAATGCTTTAGACAAAATGAAAGACTTTGCTGAAAAAGCAGCATTTGATTTACCCAAACGAAAAGACAAACAGTACGATTTCTCGATAAAAACAGTTGAAAAACGATTAAAACCACCAGAGAAAGAGAACAATCTAGAAAAATTAATCGAATCGTATTCTAGAATAACAGAATTCATAAATGGCTGTGATTGGTCGAAGTTACAAGCTGATAAAAAGACTGAAGATCCAAAGTCTTTAGAACAGAAATATTTAGATGCTAAAAACGAATTTATGTCTCAAAATCTGATGCTGATGCCGAACGATAGTCCAAAATCCGTCTTGAAAGAGGTCATCGACTTGAGTGAAGACGATGATAATATATTAACGGATATAATATCTAAAAAAATTAGCAAAGGAACATTTAATGTTGGTAAAGACGGTGCCTTATCAATATCGGTCCATCCACTTGGCAGTAAGGATATGACACTGGTACGTGAATATAGAGAACTAAAAGAAACTAACTTTCGGAATATTGTAACACTAACAGCACATACGCTTGGCCTACAAATCTAA
Protein Sequence: MTHHYSGATVYTVYAYWGRDGGAGGGGGSAAAAAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGAGLKQPSKPGKMSSSRNERSGRSSTSSSASAKDKSPSTSSNSQNMRAQYGLPKTSSPSAMHSHSQSLSSLASLNSLVSGPHQSKPSKPNAPPPSKKPSSSGIGSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDRHTGIDSLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKGGAGGTTRGRKKTISLDPPHVSLHPAAERPDRTTPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRTGTNSLSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSSTSGDYRTAADSGLNLSTKIGSESPMGLGMKMGADDDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGVRPRRAGPEAGESPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRTNDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYSPPEPHAAVSVRSMQELQNFLDLNPSPPLSTDNFSFSARTVLGEYVQPASDVGEPLIYNENEINKRLEEARALSGGRPTPPPLDRRMELARLQQAARDARRDASARSRDQARLERSEKAELAKREKEVRSQQLLEHINKNRTQLTIEPLPTIPKSVIDEWKTPEIVMGPATKSNKDRIMPPISLSLIPVSGPKDSQHSPIKTIKYDQSGWKEEIEEYNALDKMKDFAEKAAFDLPKRKDKQYDFSIKTVEKRLKPPEKENNLEKLIESYSRITEFINGCDWSKLQADKKTEDPKSLEQKYLDAKNEFMSQNLMLMPNDSPKSVLKEVIDLSEDDDNILTDIISKKISKGTFNVGKDGALSISVHPLGSKDMTLVREYRELKETNFRNIVTLTAHTLGLQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01094944;
90% Identity: iTF_01166719;
80% Identity: -