Taea017302.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Troides aeacus
Gene Symbol
egg
Assembly
GCA_033220335.2
Location
CM067286.1:8414981-8439021[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.7 1.6e+04 -3.8 0.0 29 38 1528 1537 1505 1538 0.85
2 2 4.9e-12 1.7e-08 34.6 0.0 4 74 1569 1632 1566 1635 0.87

Sequence Information

Coding Sequence
ATGGATCCTAAAAACAATTTAGAAGCTGCTACACTAAAACCCATTGGTCAAACTGCTGATGTGCCAGAAGGAAGTGACGATGGAAGCAATTCAAAAATATCTGATATTGTTAATACTTCTGTAGAAGATAATGACAAAAACATAACAAATGCTATAATTAACGTTCCTAAAGAACAATCGTTAGAAACTGCAATAAATGAAACGGAGATCAACATTATTTCAGTGGACAAAAAAGATGATCTAATTGGCAAGGAACCATTTAATTCAGATATAGTTACACCTTCAACAAAAGATGGAAGCTCAGAAAtaactaatgttattatttcatcTGAACAATATTTAGATGGAAAATTAAGTCAAGACAATGATATGAAATTATTTCCAGATGATGAAAGCTGCAGTGATATGCAAGATGAGGAAATACAGTTAAgatgggatgatgatgatatcaatttAGATTGTGTAGATGCAAGTTtatcgaaagaaaaaaaaaacatttccaaAAACATAAACAACATGGCTGTTGAAGATATGTATTTAGAAAACATGCCAGAGAAACTCAATACTACTTCATCAGATATTATGGATCAAATCGACAGGAATGTAATGGATATAAATGAGCAAAATGTCTCTCAATATAAGTgtcaagaaaataattataatacagagTGTGAAAAAATTAATACCGAACAAGATGATAATGACCCCTTACAAGAATATGAACAATGTGTTAACAAAAATAAGTGTAATGAAATTGCAAAACACAATGAATGTCTGACAATATTAATTGACTATGAAAGAGATCAATCCACTGCTCaagttgataatgataaaaacattACTCAAAATAAATGTCAAAATGTTGCACCTCAACAAGAGAATATGAAAAGTGTCATTCAAGAAGTAGGTGAGAAAATTCCAGAAGAAggtaagaaatttttatttgaatatgagAGTAAGCAAATAATAACCAATGTTGAGCAAGACAAAGATACAATCCAACCTGATTATAAAGAAAGTGTCACTGAAAATATAGTTGATAAAATAGAGGTACAAACACAAGAGAAAAATGTCATGGAACATGAGAGTGAGCAAGTCACATCTGAATTAGAAGCTAAGAAAAATCTAAATCAAAATGAATGTAAGGAAATTGTATCTCCTATTGAGGCTGAGAAAACTGTAACCAAATTTGAATGTGATGAAATTAGAGCTATAGTTGGCAATGAAGAAAATTTAACCCAAATTGAGACTAAAACTGATACAACTCCAATTGACAATGACAAAAGTGTGGCTCAACAAGAGCATGAAGAAATTGTAACTCGAATGGATAATGTGAAGAGTGACTCTCAACACAAGTCTGAAGAAATTGTAACCGAagttaacaaagaaaaaaatataaaccaaaATGATCCTGAAGAAATTGTAATGCAAGTTATCAATGAAAAAGATTTAATCCACCAAGTACATGAGGAAATTTCAGTCGAAGTTGATAATGGGAAAAGAGAAATTAAATGTGATAATGATGTTGTTACTCCCCAAGTTGATGAAGAGAAAAGTATAATACTTAGTAAGTGCAAAGAAATTACAACCCAACATGGTTTGAAGAAACCAGATATGATGTTGGAAATACCTACTCAAGAATTAATTGATTTCATGGATGAAGATGAACCAGACTTATTAGGTACTTTAGAAATGTCTTCAGATGAGGCAGCAATTGAATTATCTCATGATACTAATAGTGATGTTGATATGAGTGTTATTAATGATGCAGTAACAGTAATTAACATGGATGTTGAAATGGAAAATATCAAGTCATCAATAGAATGTGAACAAAAGGCACCAAAGGTCAATGAAACAAATCAAAATATCAATGATATTAAGGCTGTAAGCAAAAATCAATCAGAAGTTTGTCCAGAAACAATATCGTTACTTGGTTTTAAGCAATcaattaacaaagaaaaagaACAAAATGTCTCAATGGATGAACCACAACCATCAACTTCAAAAGCTTGTATGATAATGGAAATGAGAAGAGACTCTGATGAAGTTGGTGAAGTTTCTGACAGTCTAGGCCTTTTAGCTGAATCAACAAGAGTGTTAGAAGATGATGAAGAGcaagatgatgaagatgatgctgatgatgattatgattatgaCCAATATGAAGAGAATAGTAATCAAATGGGTGCTGAATATTCAGAAGACTCTAATGCTGTGACTCAAATGGAAATTGATATTGTTGACGAATGTAAAGTAAAAGAACAGACTGAAATGGATTACATATTACAAGAAAATGGATCATGTGGATTCCATATAAGAGATATCAAGACTGAAagtgatgataataaagataaaaatacagATCAATTGGTTCATTCAGGAATTTTAATAGCTGAAGACATTAAACAAGAGGAGGAAATGTCGAAGACTCCAGTTGATAATATTAACGACAATAAGGACAGTGATGCTACAAACATACCACAAGTTGACCAAAAAcaagacgATGACAGCTTGTTCACTGTTATTAAGTCAACCATACCATCATCAAATGAAGCACAGGAATCAAACTTAGATAAAGAAGAGATTGTGCTATTAGAAAGCTCATCGGATGAAGaacTATCCGaggaaattgaaaatattttacccAAAGTTAAAATACTAGGCATATCTAAAGGTGCACCTGATGTATCACAGCCTATCAAATGCCAATCAAATGTGTCACAGCAGACACTGAAACAGAAGAGTGGAAAGTTTGATACAGTTTTGAAAGATGGCTCTGATGGAAATAGTAAACAAAAAGTGACACTTAATCAAAAGTTAAAATCACCAAGAGGATTAGAAGTGTTTAGCATTGATTCAGATGACGATGATATTCTTGTTGAaaACGACGAAGCGAAAAGTAGAGGGGATAGTAGTGAGTTGAGTAAAGTCATCACATGTGTTAACATCGCCTGTCGAAGTTCACAAGAGGTGCAATATTATGCCGCTGATGCTGCAGTGTTAAAGTACTACGAGGCTGACCGGGGGAAGAAGGCAGCTGTATGCGAGCCGTGTGCAGAGGCAGTTTTCAAAAGAAACAAGgaATTGATTGagggtattaaaaataatacaccaCTCTTGGAACTAAACATAGGAAAACAAGTAGTAGAGATATCTGATTCCGATTctgaaaaagaagaagaaaccTTCGAAGAGAACAATGAAAAGATAGGAGAAGCCGGGGCCAAactcGTGGAAGAGAAACTTGCAGAGATTTTCAATACAACATGGCAGAAGTTTAATATGGACTCCAGATTAGACGAAGCCCAAACTGTCATACGTCAGGAAATGACCCGTTTGGATAaggAAAGTCAGGAAATTTATCAAATGTTAAGTGATTGTCAATCGGCTACAGATAAACTCAGAAATGAACTATATGCTACATTTGAACAGGACCGCAAGACTTTGGCTCCCATTGTTATATTTGACACAGATTACAGTatgTTTTGTGAATTTGAGGACGTTTCGCATGAAAAACACTCGaAATCGGAAAAACGTGCGAGTAAGCGGAAGTCTGCTGTTACTGATGTTCCCGCCAAAAAACTAGCAACTCTAACCTCACAAAACACGGATAACGCTAAACATGTACAGAATGTTGACGTGTCCGTGGTGAAGCTGTCCATGGAGTCAGCACCAGCCGATTTACCTCAACCGGGTGAAGTTATAAAGCCGCAATTTCGACCTGGTATGACGGTGTACGCCATGAGAAACAACTTCGGCATTTGGCTTAAAGCTAAGATTATCGAAATTCAGACTAAGAACACCTCGACGTCACCTTTTACAATGTGTCGGTTGAAATTTGAACACAAAGTGATGAGGAACGCGTTCATAACACTGCCAGCGCGCTGCATTGCTTTTGAAGACCCACCCGATGTCCGTCTTACTATAGGTACTAGAGTTATTGCCTCATCCGAAAAGAACGAGTCATTTTATTCAGGGGTTGTCGCTGAAGTTCCTAACCCGGTTAATAATTATAGgTACTTAGTGTTTTTCGACGATGGTCACGCAAAATACGCGAGGCACGCGAACACACGCCTAGTGTGCGAATGCTCGCCGCTGGTGTGGGAAGAGGTGCACCCGAATTCGCGGGACTTCGTTCGTCAGTATCTACTGTCGTATCCCGAGCGGCCAATGGTTCGTCTACATCCGAACCAAAACGTCAAGACTGAGTGGAACGgGAAATGGTGGAATTCGCGCGTGTTAGAAGTGGACGCATCTCTGGCGCTGATACTGCTCGCGGGTGATAGGATGGAATGGATATACCGTGGCTCCACCCGATTAGGTCCCTTGTTCCTGGAGTTCCAGGCTGCAGAGCGGCAGCGGTCTAGACCTATGCCGCGTTCTGGGCCACAAAATCGCACAAATATGCCGTACGTGGAGTACACCCGTTATGACGAGCCGCAGTCTTCTAAGCAGCAAACAGCTTATTCGGTGCAACAAAACGAGGAAATACGTCGTCAGCGTGCAGTAGCCAAAAAGTCAACTGTTTCTACTCAACTGCCCCCACCAGCTCCACCGAATAATGCGGCCAACCTGGACAACGTCACCAGCAGAGTTGTGtacTACACGCCGAAGAATGCAATTCGTCCATACAAGATGGTGCCGCATCAGTGTGGACCTAAATGCAAACGGACGGACGTGTTGGCGCTTAAAGACCTTAGGACCTACAATCCGTTAGCGAAACCGCTGCTTAGCGCTTGGGAGAGgcaAATAGTTCGTTTCAAAGGCCACAAAGAAGTGATGTACCGAGCGCCTTGCGGACGTCGGCTGCGCAACATGGAAGAGCTGCACCGGTACCTGCGCGCCGTCAAGTCGGATATGCCGGTCGACCTGTTCGATTTCGGTCCATCCACCCACTGCTTGGCTGAGTTCGTGCTCAATAAATGCATCGTTGGCAAGAAGGATTTATCGCATGGTAAAGAGAACGTGCCAGTGCCATGCGTCAACTACTATGATGACTCGTTGCCAGAGTTCTGCTCGTATAATACTGAGCGCACCCCCACAGCAGGTGTGCCCCTGAACCTGGACCCGGAGTTCCTGTGCGGCTGTGACTGTGACGACGACTGTAAGGATAAGACTAAATGTGGGTGTTGGAAAATGACGTTAGAGGGCGCACGGACTATTGGTCTGGAGGGTGATGTGGGCTACGTGTACCGAAGGTTACCGGATCCGTTGCCGTCCGGGATATATGAATGTAATTCAAGatgtaaatgtaaaaatacttgtttaaatCGTGTGGCTCAACATCCcttacaattaaaattacaaGTGTTTAAAACTTTGAATCGTGGATGGGGCATACGAGCTCTCAACGATGTACCAAAAGGCGCCTTCCTGTGTGTGTACGCGGGGAATTTACTCACCGACGCCACGGCTAATTTGGACGGGCTTAACGAAGGTGATGAATATCTCGCGGAGTTGGATTACATTGAAGTAGTGGAGCAGATGAAAGAGGGCTACGAGGAGGATATTCCGGAATCTCTGAAGGAGCCCGCTAAGGTGATGAAGAAGAATAGTGATGAGTACTCGGAAgatgatacatcatcatcttcagggGAGGAAGATTTGAGACTGTCGAAGGACGAAAGGGACGACGACTTCCGACCTGGATTCGTCGACGTCGGTCCCATGGAGTTCAACAAGCGCCTGCGCACCCGTGAGAAACGTAGGAAGGAAAAGCCAAACAATATAAATGTAGACAGTGTTGAAAAACAAGATGAGAAATTAGAAGAGAAGCAGGAAGTGGAACCGGAGGAGAAAGAGGAAGAGATACAAACAGAGAAAGATGGGGAGAAAGATAATGTAGATGATGATTTCATAACCATAAGTGATGATGAAGAAGTGCGAGAGCCTTCGCGGTTTACGGCACAAGCTGGAATGGATTCGAAGCATCTCGTCTCTAAGTATAGGTCAGTTCGTTCGTATTTCGGCAAGGATGAGGCGTGCTACATCATGGACGCCAAGGTCCAAGGCAACATCGGTCGATATCTTAATCACTCGTGCTGCCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTGGCGTTCTTCGCGCTGTCGCACATACGCGCCGGCACCGAGCTCACGTGGAACTACAACTACGACGTCGGCTCCGTGCCGGGGAAGGTCCTGTACTGCTACTGCGGCGCGGCCAACTGCAGGGGCAGGCTGCTCTGA
Protein Sequence
MDPKNNLEAATLKPIGQTADVPEGSDDGSNSKISDIVNTSVEDNDKNITNAIINVPKEQSLETAINETEINIISVDKKDDLIGKEPFNSDIVTPSTKDGSSEITNVIISSEQYLDGKLSQDNDMKLFPDDESCSDMQDEEIQLRWDDDDINLDCVDASLSKEKKNISKNINNMAVEDMYLENMPEKLNTTSSDIMDQIDRNVMDINEQNVSQYKCQENNYNTECEKINTEQDDNDPLQEYEQCVNKNKCNEIAKHNECLTILIDYERDQSTAQVDNDKNITQNKCQNVAPQQENMKSVIQEVGEKIPEEGKKFLFEYESKQIITNVEQDKDTIQPDYKESVTENIVDKIEVQTQEKNVMEHESEQVTSELEAKKNLNQNECKEIVSPIEAEKTVTKFECDEIRAIVGNEENLTQIETKTDTTPIDNDKSVAQQEHEEIVTRMDNVKSDSQHKSEEIVTEVNKEKNINQNDPEEIVMQVINEKDLIHQVHEEISVEVDNGKREIKCDNDVVTPQVDEEKSIILSKCKEITTQHGLKKPDMMLEIPTQELIDFMDEDEPDLLGTLEMSSDEAAIELSHDTNSDVDMSVINDAVTVINMDVEMENIKSSIECEQKAPKVNETNQNINDIKAVSKNQSEVCPETISLLGFKQSINKEKEQNVSMDEPQPSTSKACMIMEMRRDSDEVGEVSDSLGLLAESTRVLEDDEEQDDEDDADDDYDYDQYEENSNQMGAEYSEDSNAVTQMEIDIVDECKVKEQTEMDYILQENGSCGFHIRDIKTESDDNKDKNTDQLVHSGILIAEDIKQEEEMSKTPVDNINDNKDSDATNIPQVDQKQDDDSLFTVIKSTIPSSNEAQESNLDKEEIVLLESSSDEELSEEIENILPKVKILGISKGAPDVSQPIKCQSNVSQQTLKQKSGKFDTVLKDGSDGNSKQKVTLNQKLKSPRGLEVFSIDSDDDDILVENDEAKSRGDSSELSKVITCVNIACRSSQEVQYYAADAAVLKYYEADRGKKAAVCEPCAEAVFKRNKELIEGIKNNTPLLELNIGKQVVEISDSDSEKEEETFEENNEKIGEAGAKLVEEKLAEIFNTTWQKFNMDSRLDEAQTVIRQEMTRLDKESQEIYQMLSDCQSATDKLRNELYATFEQDRKTLAPIVIFDTDYSMFCEFEDVSHEKHSKSEKRASKRKSAVTDVPAKKLATLTSQNTDNAKHVQNVDVSVVKLSMESAPADLPQPGEVIKPQFRPGMTVYAMRNNFGIWLKAKIIEIQTKNTSTSPFTMCRLKFEHKVMRNAFITLPARCIAFEDPPDVRLTIGTRVIASSEKNESFYSGVVAEVPNPVNNYRYLVFFDDGHAKYARHANTRLVCECSPLVWEEVHPNSRDFVRQYLLSYPERPMVRLHPNQNVKTEWNGKWWNSRVLEVDASLALILLAGDRMEWIYRGSTRLGPLFLEFQAAERQRSRPMPRSGPQNRTNMPYVEYTRYDEPQSSKQQTAYSVQQNEEIRRQRAVAKKSTVSTQLPPPAPPNNAANLDNVTSRVVYYTPKNAIRPYKMVPHQCGPKCKRTDVLALKDLRTYNPLAKPLLSAWERQIVRFKGHKEVMYRAPCGRRLRNMEELHRYLRAVKSDMPVDLFDFGPSTHCLAEFVLNKCIVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCDDDCKDKTKCGCWKMTLEGARTIGLEGDVGYVYRRLPDPLPSGIYECNSRCKCKNTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPESLKEPAKVMKKNSDEYSEDDTSSSSGEEDLRLSKDERDDDFRPGFVDVGPMEFNKRLRTREKRRKEKPNNINVDSVEKQDEKLEEKQEVEPEEKEEEIQTEKDGEKDNVDDDFITISDDEEVREPSRFTAQAGMDSKHLVSKYRSVRSYFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIRAGTELTWNYNYDVGSVPGKVLYCYCGAANCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01115722; iTF_01495796; iTF_01495066;
90% Identity
iTF_01495796; iTF_01495066;
80% Identity
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