Oale003988.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ornithoptera alexandrae
Gene Symbol
egg
Assembly
GCA_029030555.1
Location
JARDVY010000018.1:2372261-2396244[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 5.8 1.4e+04 -3.7 0.0 29 38 1464 1473 1438 1474 0.83
2 2 6.7e-12 1.6e-08 34.6 0.0 4 74 1505 1568 1502 1571 0.87

Sequence Information

Coding Sequence
ATGGATTCTAAAAACAATTCAGAAGCTGCTACACTAGAACCCATCAATCAAACGGCTGATGTGCAAGAAGGAGGTAACAATAGAagccatttaaaaatatctgatATTGTTAATACTTCTGTAGAAGATAATgacaaaaacataataaacgCTGTAATTAACCTTCCTAAAGAACAATCGCTACAAACTGCAATAAATGAAACGGAGATCAACATTATTTCAGTAGACAAAAGAGATGATCTAATTGGCAAGGAACCATTTAATTCAGAAGATATAGTTACACCTTCAACAAAAGATGGAAGCTCAGAAATAACTAGTGTTATTATTTCACCTGAACAATATTTAGATGGAAAATTAAGTCAAGACAATGACATGAAATTATTTCCAGACGATGAAAGCTGTAGTGATATGCAAGATGAGGAAATACAGTTAAGatgggatgatgatgatatcaacTTAGATTGTGTAGATGTAGCTTTatcagaagaaaaaaaaaacatttctaaagACATTAACAACTTGGCTGTTGAAGATATGTATTTAGAAAACATACCAGAAAAACTCAATACTACTTCATCAGATATTGCGGATCAAATTGACAGAAATATAATGGATATAAACGAGAAAAATGTTTCTCAATATAAGTGTCAAGAAGATAGTTATGACACAGAgtgtgaaaaaattaatacccAACAAGATGATAAGCACCCCTTACAAGAATATGAACaatgtgttaataaaaataagtgtaATGAAGTTGCAAAACAAGATGAATGTCTGACAATATTAATTGACCAATCCACTGCTCAAGTTGAGAATGATAAAAACATACCTCACCATAAATGCGAAAATATTGCACCTCAACAAGAGAATATGAAAAGTCAACCTGATTGTAAAGAAAGTGTCactgaaaatataattgataaaatagaGCAACAAACACAAGAGAAAAATGTCAAGGAACATGAGAGTGAGCAAGTCACATCTGAATTAGAGGCTAAGAAAAATCTAAACCAAAATGAACATAAGGAAATTGTATCCCCTATTGATGCTGAGAAAAGTGTAACCAAAAATAAATGTGTAGAAATTACAGCTATAGTTGGCAATGAAGAAAATTTAACTCAATTTGAGACTAAAACTAATGCAATGCCAATTGACAATGACAAAAGTGTGGCTCAAAAAGAGCATGAAGAAATTGTAACTCTAATAGACAATGTGACAAGTGACTCTCAACACGCATCTGATGAAATTGTAACCAAAggtaacaaagaaaaaaatataaaccaaAATGATTGcgaaaaaattgtaatgcaAGATATCaatgaaaaagatttaatCCAACAAGTACACGAGGAAATTTCAGTCGAAGTTGATAATgggaaaaaagaaattaaaaatgaaaatgatgtTATGCCCCAAGTTGATGAAGAGACAAGTATAATACTTAGCAGGTGTAAAGAAATTACAACCCAACATGGTTTGAAGAAACCGGATATGATGTTGGAAATACCTACTCAAGAATTAATTGATTTcatggatgatgatgaaccagaCTTATTAGGTACTTTAGAAATGTCTTCAGATGAGACAGCAATTGAAATATCACATGATAATAATAGTGATGTTGATATGAGTGTTATTAATGATGAGGTAACAGTAATTAACATGGATGTTGAAATGGAAAATATCAAATCATCAATAGAATGTGAACAAAAGGCACCAAAggacaatgaaaaaaatcaaattatcaATGATATTAAGGCTGTAAGCAAAAATCAGTTAGAAGTTTGTCCAGAAACAATATCACTACTaggttttaaacaattaattaacaaagaaagagaacaaaatatctttatgGATGAACCACAACCATCAACTTCAAAAGCTTGTATGATAATGGAAATGAGAAGAGACTCTGATGAAGTTGGTGAAGTTTCTGACAGTCTAGGCCTTTTAGCTGAATCAACAAGAGTGTTAGAAGATGATGAAGAGcaagatgatgaagatgatgctgatgatgattttgatTATGACCAATATGAAGAGAGTAGTAATCAAATGGGAGCTGAATTTTCAGAAGATTCTAATGCTGTGAACTCAGAGACAGATATTGTAAGAGTTACTCAAATGGAAATTGCTGATGTTgacaaatgtaaagaaaaagaacAGACTGAAATAGATTACATAGTACAAGAAAATGAATCATGTGGATTCCATATAAGTGATATCAAGACTCAAagtgatgataataaagataatagtACAGACCAATCGGTTCATTCAGAAATTTTAATAGCTGAAGACAACAAACTAAAGACAGAGGAAATGTCTAAGACTCTAGTTGATAACATTAACGACAATAAGGACACTGATGCTACAAATATACCGCAAGTTGACCAAAAACaagACAATGAAAGCTTGTTCACCATTGTTGATTCTACCTTACCATCATCAAATGATGCACAGGAATCAAATTTAGATAAAGAAGAGATTGTGCTATTAGAAAGCTCCTCAGATGAAGGCATATCTAAAAGTGTGCCTGATGTATCACAGCCAAATGCATTACAGCAGACACTGGAACAGAATAGTGGAGAGTTTGATACAGTTTTGAAGAACTACTCTGATGAATGTAGTAAACAAAAGTTAAAATCACCAAGAGGGTTAGAAGTGTTTAGTATAGATTcagatgacgatgataatcttgctaaaaaGGATAGTAGTGTGTTGTGTAAAGCCATCATATGTGTTAACATCGCCTGTCGAAGTTCACAAGAAGTGCAATATTACGTCGCTGATGCTGCAGTGTTAAAGTACTATGAGGCGGACCGGGGGAAGAAGGCAGCTGTATGCGAGCCTTGCGCAGAAGCAGTTTTCAAAAGAAACAAGgaATTGATCGagggtattaaaaataatacaccaCTCTTGGAACTAAACATCGGAAAACAAATAGTAGAGATATCTGATTCCGATTctgaaaaagaagaagaaaccgTTGAAGAGAACAATGAAAAGATAGGCGAAGCCGGAGCCAAactcATGGAAGAGAAACTTGCAGAAATTTTCAATACAACATGGCAGAAGTTTAATATGGACTCCAGACTAGACGAGGCCCAAACTGTGATACGACAAGAAATGAGCCGCTTGGAAAgGGAAAGTCAGGACATTAATCAAATGTTAAATGAGTGTCAATCGGCAACAGATAAACTCAGAAATGAACTATACGCTACATTTGAACAGGAACGCAAGACTTTGGCacccattattatatttgacacTGATTACAGTATGTTTTGTGACTTTGAAGATGTTACGCATGAAAAACACTCGAAAACAGAAAAACGCGCGAGTAAGCGGAAGTCTGTCGTTAATGAGTTTCCCACCAAAAAGCCATTAATTCTATCCATACAAAACATGGATAACGCTAAACATGTACAGAATGTTGACGTGTCCGTGGTGAAACTGTCCGTGGAGTCAGCACCATCCGATTTACCTCAACCGGGTGAAGTTATCAAGCAGCAATTGCGAAGCGGCATGACGGTGTACGCCATGAGAAACAACTTCGGTATTTGGCTTAAAGCTAAGATTATCGAAATTCAGAATAAGAACGCCgCGTCGGCACCTTTTACAATGTGTCGCTTGAAGTTTGAACACAAAGTGATGAGAAATGCGTTCATAACACTGCCCGCGCGCTGCATTGCTTTTGAAGACCCGCCCGACGTCCGTCTTACTATAGGTACTAGAGTTATCGCATCATCCGAAAAGAACGAGTCATTTTATTCAGGGGTTGTCGCTGAAGTTCCTAACCCGGTTAATAATTATAGGTACTTAGTGTTTTTCGACGATGGTCACGCAAAATACGCGAGGCACGCGAACACCCGCCTGGTGTGCGAATGCTCGCCGCTGGTGTGGGAGGAAGTGCACCCAAATTCGCGGGACTTCGTTCGTCAGTATCTACTGTCGTATCCCGAGCGGCCCATGGTTCGTCTACATCCGAACCAAAACGTCAAGACCGAGTGGAACGGGAAATGGTGGAACTCGCGCGTGTTAGAAGTGGACGCATCTCTGGCGCTGATACTGCTCGCGGGTGATAGGATGGAATGGATATACCGTGGCTCCACTCGCTTAGGTCCCTTGTACTTGGAATTCCAGGCTGCAGAGCGGCAGAGGTCTAGACCTATGCCGCGGTCTGGGCCACAAAATCGGACAAATATGCCGTACGTGGAGTACACCCGTTACGACGAGCCGCACCCTTCTAAACAGCAAACAGCTTATTCAGTGCAACAAAACGAgGAAATACGTCGTCAGCGTGCCGTAGCCAAAAAGTCGACAGTTTCTTCTCAGCTGCCACTACCAGCTCCACCGAGTAATGCGGCCAACCTGGACAACGTCACCAGCAGAGTTGTGtACTACACGCCGAAGAATGCGATTCGTCCATACAAGATGGTGCCGCATCAGTGTGGACCTAAATGCAAACGTACCGACGTGTTGGCGCTTAAAGACCTTAGGACCTACAATCCGTTAGCGAAGCCGCTGCTTAGCGCTTGGGAGAGgcaAATAGTCCGTTTCAAAGGCCACAAAGAAGTGATGTACCGAGCACCTTGCGGCCGTCGGCTGCGCAACATGGAAGAGCTGCACCGGTACCTGCGCGCCGTCAAGTCGGATATGCCGGTCGACCTGTTCGATTTCGGTCCATCCACCCACTGCTTAGCAGAGTTTGTACTTAATAAATGCATTGTTGGCAAGAAGGATTTATCGCATGGTAAAGAGAACGTGCCGGTGCCGTGCGTCAACTACTATGATGACTCGTTGCCAGAGTTCTGCTCGTATAATACTGAGCGCACCCCCACAGCAGGTGTGCCGCTGAACCTGGACACGGAGTTCCTGTGCGGCTGCGACTGTGACGACGACTGTAAGGATAAGACTAAATGTGGATGTTGGAAAATGACGTTAGAGGGCGCTCGGACTATTGGCCTGGAAGGTGATGTGGGCTACGTGTACCGAAGGTTACCGGACCCGTTGCCGTCCGGGATATATGAATGTAATTCAAgatgtaaatgtaaaaatacctGTTTAAATCGTGTGGCCCAGCATCCcctacaattaaaattacaaGTGTTTAAAACTCTGAATCGTGGATGGGGCATACGAGCTCTCAACGATGTACCAAAAGGCGCCTTCCTGTGTGTATACGCGGGGAACTTGCTCACCGACGCTACGGCTAATTTGGACGGGCTGAACGAAGGGGATGAATATCTCGCGGAGTTGGATTACATTGAAGTAGTGGAGCAGATGAAAGAGGGCTACGAGGAGGATATCCCGGAATCTCTGCGGGAGCTTGCTGGGGATAGGAAGTCTACAGATGAGTACTCTGAAGATGAGACATCATCTTCAGAGGAGGAAGATTTGAGACTGTCGAAGGACGAGAGGGACGACGACTTCCGACCTGGATTCATCGACGTCGGTCCCATGGAGTTCAACAAGCGCCTGCGCACTCGTGAGAAACGCAAGAAGGAAAAACCAAACAATGCAAATGATGATAGTATTGAAAAACAAGATGAGAAATTAGAAGAGAAGCCGGATGTGGAACCAGAAGAGAAAGaggaagagaaagagaaagacaAAGAGAAAGAGGAAGAGAAAGaggaagagaaagagaaagaggaAGAGAAAGAGGAAGAGAAAGAGGAAGAGAAAGAGGAAGAGAAAGAGGAAGAGAAAGAGGAAGAGAAAGAGGAAGAGATACAAACAGAGAAATATGGGGAGAAGGATAATGTAGATGATGATTTCATAACCATaagtgatgatgaagaagTGAGAGAGCCTTCGCGGTTTACGGCACAAACTGGAATGGATTCGAAGCATCTGGTCTCGAAGTATAGGTCAGTTCGTTCGTATTTCGGCAAGGATGAGGCGTGCTACATCATGGACGCCAAGGTCCAAGGCAACATCGGTCGATATCTTAATCACTCGTGCTGCCCGAATGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTGGCGTTCTTCGCGCTGTCGCACATACGCGCCGGCACCGAGCTCACGTGGAACTACAACTACGACGTCGGCTCCGTGCCGGGGAAGGTCCTGTACTGCTACTGCGGCGCAGCCAACTGCAGGGGCAGGCTGCTCTGA
Protein Sequence
MDSKNNSEAATLEPINQTADVQEGGNNRSHLKISDIVNTSVEDNDKNIINAVINLPKEQSLQTAINETEINIISVDKRDDLIGKEPFNSEDIVTPSTKDGSSEITSVIISPEQYLDGKLSQDNDMKLFPDDESCSDMQDEEIQLRWDDDDINLDCVDVALSEEKKNISKDINNLAVEDMYLENIPEKLNTTSSDIADQIDRNIMDINEKNVSQYKCQEDSYDTECEKINTQQDDKHPLQEYEQCVNKNKCNEVAKQDECLTILIDQSTAQVENDKNIPHHKCENIAPQQENMKSQPDCKESVTENIIDKIEQQTQEKNVKEHESEQVTSELEAKKNLNQNEHKEIVSPIDAEKSVTKNKCVEITAIVGNEENLTQFETKTNAMPIDNDKSVAQKEHEEIVTLIDNVTSDSQHASDEIVTKGNKEKNINQNDCEKIVMQDINEKDLIQQVHEEISVEVDNGKKEIKNENDVMPQVDEETSIILSRCKEITTQHGLKKPDMMLEIPTQELIDFMDDDEPDLLGTLEMSSDETAIEISHDNNSDVDMSVINDEVTVINMDVEMENIKSSIECEQKAPKDNEKNQIINDIKAVSKNQLEVCPETISLLGFKQLINKEREQNIFMDEPQPSTSKACMIMEMRRDSDEVGEVSDSLGLLAESTRVLEDDEEQDDEDDADDDFDYDQYEESSNQMGAEFSEDSNAVNSETDIVRVTQMEIADVDKCKEKEQTEIDYIVQENESCGFHISDIKTQSDDNKDNSTDQSVHSEILIAEDNKLKTEEMSKTLVDNINDNKDTDATNIPQVDQKQDNESLFTIVDSTLPSSNDAQESNLDKEEIVLLESSSDEGISKSVPDVSQPNALQQTLEQNSGEFDTVLKNYSDECSKQKLKSPRGLEVFSIDSDDDDNLAKKDSSVLCKAIICVNIACRSSQEVQYYVADAAVLKYYEADRGKKAAVCEPCAEAVFKRNKELIEGIKNNTPLLELNIGKQIVEISDSDSEKEEETVEENNEKIGEAGAKLMEEKLAEIFNTTWQKFNMDSRLDEAQTVIRQEMSRLERESQDINQMLNECQSATDKLRNELYATFEQERKTLAPIIIFDTDYSMFCDFEDVTHEKHSKTEKRASKRKSVVNEFPTKKPLILSIQNMDNAKHVQNVDVSVVKLSVESAPSDLPQPGEVIKQQLRSGMTVYAMRNNFGIWLKAKIIEIQNKNAASAPFTMCRLKFEHKVMRNAFITLPARCIAFEDPPDVRLTIGTRVIASSEKNESFYSGVVAEVPNPVNNYRYLVFFDDGHAKYARHANTRLVCECSPLVWEEVHPNSRDFVRQYLLSYPERPMVRLHPNQNVKTEWNGKWWNSRVLEVDASLALILLAGDRMEWIYRGSTRLGPLYLEFQAAERQRSRPMPRSGPQNRTNMPYVEYTRYDEPHPSKQQTAYSVQQNEEIRRQRAVAKKSTVSSQLPLPAPPSNAANLDNVTSRVVYYTPKNAIRPYKMVPHQCGPKCKRTDVLALKDLRTYNPLAKPLLSAWERQIVRFKGHKEVMYRAPCGRRLRNMEELHRYLRAVKSDMPVDLFDFGPSTHCLAEFVLNKCIVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDTEFLCGCDCDDDCKDKTKCGCWKMTLEGARTIGLEGDVGYVYRRLPDPLPSGIYECNSRCKCKNTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPESLRELAGDRKSTDEYSEDETSSSEEEDLRLSKDERDDDFRPGFIDVGPMEFNKRLRTREKRKKEKPNNANDDSIEKQDEKLEEKPDVEPEEKEEEKEKDKEKEEEKEEEKEKEEEKEEEKEEEKEEEKEEEKEEEKEEEIQTEKYGEKDNVDDDFITISDDEEVREPSRFTAQTGMDSKHLVSKYRSVRSYFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIRAGTELTWNYNYDVGSVPGKVLYCYCGAANCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01494329;
90% Identity
-
80% Identity
-