Basic Information

Insect: Trichoplusia ni
Gene Symbol: KLHL5
Assembly: GCA_003590095.1
Location: NC:2991608-2998919[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.4e-30 3.2e-28 97.8 0.3 6 109 62 163 58 164 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.4e-30	3.2e-28	97.8	0.3	6	109	62	163	58	164	0.94

Sequence Information

Coding Sequence: ATGTCTGCAAATGATTCTCAGAAAGCTGAGGCTTCTAAAGACAACATATCAAATAATTCGATCGATGAAGGCTTACCAAGAGAGCTAAGTCAGTTAAGTCTTTCAAGTGCTTCAAGTCAAGAAGAATTCTTTTGTGACAAAGGACATTCTGGAATagcattgaaaaatatattcagcTATTATCAATCACAAAAATTATGCGACGTCGCCCTAATCGCCGGAGGATGCAGGATACCCGCACACAAAATACTTCTGGCATCATGCAGCGAGTACTTTGCTGCAATGTTCACAGGATCCCTAAGAGAGGCCCAGTCCAGTGAGATAACACTTGAGAGAGTTGATCCACAAGCACTACAAGACCTTGTGCACTATTGTTACACTGGCACCATAGaaCTGAGAGAGGAGACAGTTGAAGTTCTTCTCTCCACATCCAGCTTGTTGCAGCTTACTTCAGTCACAGAAGCTTGTTGTGCTTTTTTACTGCGGCAGTTGGACCCCTGTAATTGTCTGGGAATAGCTTTATTTGCGGAACAGCAATCCTGTCTGGATTTACACAAAAGCGCTTTGAAATACACATACCAACACTTTATGCAGGTGGTGAAACATCAAGAATTCTTAGCTCTGCAAGCTGACCAGTTGGCCAACTTGCTGAAGTCAGATGATCTTAATGTAGTGACTGAAGAAAATGTGTTCGAGAGTCTCATGACATGGGTACAACATGACAGTGCCAAAAGGGAAAGCCATTTAGCTACACTACTGAAGCTAGTTAAACTGCCACTACTTTCATCAGAGTACTTAATAGACAAAGTGGAGCTGGCTTGTGGTAATGTCCCAGAATGTCAACCCCTTATAATGGAGGCTGTGAAGTGGCATCTCTTACCGGAACGACGATCTCTCCTGTTCTCACATCGCACACGGCCGCGTACGTCTACTATTGGTCGGCTTCTAGCCATCGGTGGCATGGATGGATACAAGGGTGCCAGCAATATGGAGATGTACGACCCCAGAACAAACACATGGACCCCATTTATGAGAATGGGAGCTAGGAGGTTACAGTTTGGAGTGGCAGTGATGCAAAACAAACTTGTTGTAGTTGGTGGCAGAGATGGTCTTAAGACTTTGAATACGGTGGAATGCTTTGATCTCACTTCATTGAGCTGGAGTGTCCTGGCTCCTATGAATACACATAGACATGGCCTTGGTGTGGCCGTACTTGGAGAAGGTCCAAACTCGCCGGTATACGCCGTCGGCGGACACGACGGATGGATATACTTGAATTCTGTAGAAAGATGGGACGCGTGCTCGCGCTCGTGGACGATGGTGTCGCCGATGGCGGGCGCGCGCAGCACGTGCGGCGTGGCGGCGCTGCGCGGGCGCCTGTTCGCGGTGGGCGGCCGCGACGGCGGCGCCTGTCTGCGCTCCGTCGAGTGCTACGACCCCAACACCAACCACTGGACCAACTGCGCGCCCATGACGCGCCGCCGCGGGGGCGTCAGCGTATGCGCTGCAGGAAACTACTTATACGCTCTCGGTGGTCATGAAGCACCTGCCAATACTGTCGGTGGTCGACTGGCGTGCGTCGAGCGGTATGATCCAGTCGCCGATTCCTGGGTCCTGCTAGCCCGCCTCTCGTACGGAAGGGATGCCATAGGATCCTGTCTACTAGGGGATCGGATTGTCGCTGTCGGAGGCTACGATGGAGTTCAATACCTGTGTGTGGTGGAGGTGTACGACTCGGAGTCCAACTGCTGGCGCAAGCTGGCGCCGCTGAGTACAGGCCGCGCGGGCGCCGCCGTGGTCGCCGTGCCTGCGCCCAAAAACTCCTTCTGA
Protein Sequence: MSANDSQKAEASKDNISNNSIDEGLPRELSQLSLSSASSQEEFFCDKGHSGIALKNIFSYYQSQKLCDVALIAGGCRIPAHKILLASCSEYFAAMFTGSLREAQSSEITLERVDPQALQDLVHYCYTGTIELREETVEVLLSTSSLLQLTSVTEACCAFLLRQLDPCNCLGIALFAEQQSCLDLHKSALKYTYQHFMQVVKHQEFLALQADQLANLLKSDDLNVVTEENVFESLMTWVQHDSAKRESHLATLLKLVKLPLLSSEYLIDKVELACGNVPECQPLIMEAVKWHLLPERRSLLFSHRTRPRTSTIGRLLAIGGMDGYKGASNMEMYDPRTNTWTPFMRMGARRLQFGVAVMQNKLVVVGGRDGLKTLNTVECFDLTSLSWSVLAPMNTHRHGLGVAVLGEGPNSPVYAVGGHDGWIYLNSVERWDACSRSWTMVSPMAGARSTCGVAALRGRLFAVGGRDGGACLRSVECYDPNTNHWTNCAPMTRRRGGVSVCAAGNYLYALGGHEAPANTVGGRLACVERYDPVADSWVLLARLSYGRDAIGSCLLGDRIVAVGGYDGVQYLCVVEVYDSESNCWRKLAPLSTGRAGAAVVAVPAPKNSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00425569; iTF_00001282; iTF_00327181; iTF_00622093; iTF_01073713; iTF_01221715; iTF_00185431; iTF_00186391; iTF_00878947; iTF_01494403; iTF_01176263; iTF_00790411; iTF_01141771; iTF_00197453; iTF_01115792; iTF_01402802; iTF_00958035; iTF_01139667; iTF_00855957; iTF_01495125; iTF_00195254; iTF_01495862; iTF_00840376; iTF_01143193; iTF_00204442; iTF_00249791; iTF_00275428; iTF_01403561; iTF_00163082; iTF_00161671; iTF_00796622; iTF_01090901; iTF_00288151; iTF_00650141; iTF_00256057; iTF_00642472; iTF_00144758; iTF_00257049; iTF_00786916; iTF_00406018; iTF_00933954; iTF_01217606; iTF_00164489; iTF_01248307; iTF_01178745; iTF_00288955; iTF_00403934; iTF_00925854; iTF_00111781; iTF_01118447; iTF_01117468; iTF_00924897; iTF_01535046; iTF_01533187; iTF_00274533; iTF_00301318; iTF_00736713; iTF_01534070; iTF_00018279; iTF_00383819; iTF_00017454; iTF_00171958; iTF_00449292; iTF_00685576; iTF_01031244; iTF_01029385; iTF_00447373; iTF_01440205; iTF_00445327; iTF_01026448; iTF_00177297; iTF_00810226; iTF_00809284; iTF_01340340; iTF_00831353; iTF_01063868; iTF_01062944; iTF_00273728; iTF_00115045; iTF_01092167; iTF_00771177; iTF_01202570; iTF_00985263; iTF_01203343; iTF_01205007; iTF_01205808; iTF_01204179; iTF_01206675; iTF_00954677; iTF_00896983; iTF_00689475; iTF_01220748; iTF_00640526; iTF_00077615; iTF_00114191; iTF_01172498; iTF_00649237; iTF_01155478; iTF_00012120; iTF_00411582; iTF_00923814; iTF_00025321; iTF_00120645; iTF_01153111; iTF_00720464; iTF_00013186; iTF_00146544; iTF_00044614; iTF_00033922; iTF_00948007; iTF_00674396; iTF_00156359; iTF_00960264; iTF_00871425; iTF_00419074; iTF_01017829; iTF_00648232; iTF_00461677; iTF_00959504; iTF_00289746; iTF_01034706; iTF_01033843; iTF_00752181; iTF_00421463; iTF_00420637; iTF_00842782; iTF_01388607; iTF_00006377; iTF_01081707; iTF_01061994; iTF_00353261; iTF_00354276; iTF_00778094; iTF_00781928; iTF_00621322; iTF_00457325; iTF_00458157; iTF_00213648; iTF_00723249; iTF_00247314; iTF_00782738; iTF_00159955; iTF_00212659; iTF_00248215; iTF_00780343; iTF_01181975; iTF_00775356; iTF_00781120; iTF_00261967; iTF_00783697; iTF_00695794; iTF_00687965; iTF_00155408; iTF_00968144; iTF_00710321; iTF_00010258; iTF_00009175; iTF_01141010; iTF_00205300; iTF_01021411; iTF_01151311; iTF_01018678; iTF_00953657; iTF_01222580; iTF_01142477; iTF_01140291; iTF_01147465; iTF_01547963; iTF_01562100; iTF_00430762; iTF_00318187; iTF_00357751; iTF_00358743; iTF_00235957; iTF_00876297; iTF_01490249; iTF_00875435; iTF_01401400; iTF_00236735; iTF_00356406; iTF_00818429; iTF_00325527; iTF_00835704; iTF_00836685; iTF_01360807; iTF_00822083; iTF_00405124; iTF_00823142; iTF_00282539; iTF_00636619; iTF_01197899; iTF_00157325; iTF_00677774; iTF_00908976; iTF_00869778; iTF_01166836; iTF_00823990; iTF_00707096; iTF_00441663; iTF_01152287; iTF_01332928; iTF_01502208; iTF_00148569; iTF_00709370; iTF_01492126; iTF_01080826; iTF_01080001; iTF_01079158; iTF_00700222; iTF_01157955; iTF_01159523; iTF_01302502; iTF_00683464; iTF_01335113; iTF_00682546; iTF_00828104; iTF_00345930; iTF_00638750; iTF_01076650; iTF_01173393; iTF_01339050; iTF_01538892; iTF_00342318; iTF_00302255; iTF_01192835; iTF_01464272; iTF_00323601; iTF_00276562; iTF_00113412; iTF_00008134; iTF_00027882; iTF_00806833; iTF_00178331; iTF_01336987; iTF_00026974; iTF_00889362; iTF_00931576; iTF_00794780; iTF_00696564; iTF_00851937; iTF_01095073; iTF_00686466; iTF_01208386; iTF_01336035; iTF_00432356; iTF_00908036; iTF_01264804; iTF_01317412; iTF_01528420; iTF_01532228; iTF_00122533; iTF_00666629; iTF_00850917; iTF_01084389; iTF_01429157; iTF_00043686; iTF_00121574; iTF_00446342; iTF_00703046; iTF_00772134; iTF_00888390; iTF_01170694; iTF_01361766; iTF_00040007; iTF_00406855; iTF_00811143; iTF_00844487; iTF_01209415; iTF_01425223; iTF_00699336; iTF_01085512; iTF_01509704; iTF_00123497; iTF_00187273; iTF_00407689; iTF_01285673; iTF_00072938; iTF_01183018; iTF_00300363; iTF_00622955; iTF_00632875; iTF_00050060; iTF_01171564; iTF_01501260; iTF_00712045; iTF_00909805; iTF_00952813; iTF_01526189; iTF_00361742; iTF_00365038; iTF_00791310; iTF_01064782; iTF_01260238; iTF_00704111; iTF_00951951; iTF_01444015; iTF_00433264; iTF_00994448; iTF_00037937; iTF_00726577; iTF_00837681; iTF_01503089; iTF_00124402; iTF_00408562; iTF_00705138; iTF_00906290; iTF_01341426; iTF_00267315; iTF_00702099; iTF_00706131; iTF_00758387; iTF_00036948; iTF_00207092; iTF_00284660; iTF_00412628; iTF_00698420; iTF_00907156; iTF_01180404; iTF_01280500; iTF_00038965; iTF_00041013; iTF_00119701; iTF_00143158; iTF_00147638; iTF_00250582; iTF_00737590; iTF_01342326; iTF_00819287; iTF_01030359; iTF_00663192; iTF_00913720; iTF_00042777; iTF_00377209; iTF_00942937; iTF_01094169; iTF_01281465; iTF_00041914; iTF_00112602; iTF_00374330; iTF_00661434; iTF_00961050; iTF_00745915; iTF_00033020; iTF_00701180; iTF_01279388; iTF_01363228; iTF_01503996; iTF_00074653; iTF_00697469; iTF_01527453; iTF_01529309; iTF_00206206; iTF_00321694; iTF_00364158; iTF_00662334; iTF_00785310; iTF_01179582; iTF_00382783; iTF_00784511; iTF_00035840; iTF_00834752; iTF_01219872; iTF_00680693; iTF_00833190; iTF_01247254; iTF_00681755; iTF_00448252; iTF_00319028; iTF_00772988; iTF_00824863; iTF_00858687; iTF_00341442; iTF_01010505; iTF_00973898; iTF_01125578; iTF_00787787; iTF_00820203; iTF_01230797; iTF_01544049; iTF_00859608; iTF_01544984; iTF_01543065; iTF_01430042; iTF_00000443; iTF_00429147; iTF_01545851; iTF_00290812; iTF_00063709; iTF_01368221; iTF_01124703; iTF_01358975; iTF_00428256; iTF_01546752; iTF_01416957; iTF_01416004; iTF_00467495; iTF_00761800; iTF_00468265; iTF_01437198; iTF_00724047; iTF_01251952; iTF_01083475; iTF_01561215; iTF_01507327; iTF_00843641; iTF_00635520; iTF_01134914; iTF_01154212; iTF_00802021; iTF_00660423; iTF_01072649; iTF_00462508; iTF_01463404; iTF_00634606; iTF_00986350; iTF_01135886; iTF_00659539; iTF_00656245; iTF_00658525; iTF_00208014; iTF_00208980; iTF_01506464; iTF_01508173;
90% Identity: iTF_01332928;
80% Identity: -