Hves020133.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyles vespertilio
Gene Symbol
KLHL5
Assembly
None
Location
HLhylVes1:10153361-10176139[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.8e-32 3.5e-29 101.6 0.4 6 109 62 163 58 164 0.96

Sequence Information

Coding Sequence
ATGTCTGGCTGTGATACTCAGAAAGCGGAGACTTCTAAAGATAATATATCTACTAACTCCATCGATGAAGGTCTGCCTCGCGAACTAAGTCAGTTAAGTCTGTCGAGTGCTTCAAGTCAAGATGAATCTTTTTGTGACAAAGGACATTCAGAAACGACACTGAAAAAAATATACGGTTATTACCAGTCCCAACAACTGTGCGATGTGGCACTTATAGCTGGAGGATGCAGGATTCCAGCACACAAAGTACTATTAGCATCATGCAGTGAATATTTTGCTGCTATGTTCACTGGCTCATTGAGAGAGGCTCAGCTGACAGAGATAACACTTGAGCGTGTTGACTCACAGGCACTCCAAGCGCTTGTACACTACTGCTACACAGGCACTATTGAATTAAGAGAGGAAACTGTAGAAGTGTTGCTTTCAACAGCAAGTCTTTTACAATTGCACTCGGTGACTAATGCATGTTGTGCATTCCTGAAAAAACAGTTGGATCCATGTAACTGTTTGGGAATAGCTTTATTTGCAGAACAACAATCTTGTTTGGATTTACACAAGAGTGCTTTAAAATACACTTACCAACATTTTATGCAGGTAGTGAAACATCAAGAATTTTTAGCATTACAAGCAGACCAGTTAGCAAGCTTGCTGAAGTCAGATGATCTCAATGTAGTTACCGAAGAGAATGTATTTGAGAGTCTAATGGCATGGGTACAACATGATAGTACTACTAGAGAGGAACATTTGCCAACATTACTGAAACTCATCAAATTACCTTTATTATCATCAGAGTATTTGATTGATAAAGTAGAGTTAGCATGTGGCAATGTGCCTGAATGCCAACCACTTATCATGGAGGCTGTGAAATGGCATCTTTTACCTGAAAGGCGGTCTTTATTATTCTCACATAGGACCAGACCTAGAACTTCAACTATTGGCCGTCTTCTAGCTATAGGAGGGATGGATGGATATAAGGGCGCCAGTAACATGGAAATGTACGATCCACGGACAAATACTTGGACACCATTTATGAGAATGGGCGCAAAGAGATTACAATTTGGAGTAGCTGTGATGCAGAATAAACTTATTGTTGTTGGTGGCAGGGATGGACTAAAGACCTTAAATACGGTGGAGTGTTTCGATTTGACGTCATTGAGCTGGAGCACACTGGCGCCGATGAATACACACAGGCATGGTCTAGGCGTCGCAGTGCTGGGCGATGGACCAAACTCGCCCGTATATGCAGTTGGTGGTCACGACGGATGGATATATTTAAACTCAGTTGAACGTTGGGACGCGTGCTCGCGCACGTGGACGATAGTGGCGCCGATGGCGGGCGCGCGCAGCACGTGCGGCGTGGCGGCGCTGCGCGGCCGCCTGTACGCGGTGGGCGGGCGCGACGGCGGCGCGTGTCTGCGCTCCGTCGAGTGCTACGACCCCGCCACCAACCACTGGACAAACTGCGCGCCCATGACGCGTCGCCGGGGTGGTGTTAGTGTGTGCGCTGCCGGCAGCTACCTGTACGCTCTGGGCGGGCACGAGGCGCCCGCCAACACGGTGGGCGGCCGCCTCGCATGCGTCGAGCGGTACGACCCCGTGGCAGACACCTGGCTGCTACTGGCACGCCTGTCATATGGCAGGGACGCCATCGGATCCTGTCTGCTTGGTGACAGAATTGTTGCTGTTGGCGGGTACGACGGCGTGCAGTACCTGTGCGTGGTGGAGGTGTACGACTCCGGTTCCAACGTGTGGCGCAAGCTGGCGCCGCTGAGCACGGgccgcgcgggcgccgccgtggtggccgtgccgccgccgcGCAACCTCTTCTGA
Protein Sequence
MSGCDTQKAETSKDNISTNSIDEGLPRELSQLSLSSASSQDESFCDKGHSETTLKKIYGYYQSQQLCDVALIAGGCRIPAHKVLLASCSEYFAAMFTGSLREAQLTEITLERVDSQALQALVHYCYTGTIELREETVEVLLSTASLLQLHSVTNACCAFLKKQLDPCNCLGIALFAEQQSCLDLHKSALKYTYQHFMQVVKHQEFLALQADQLASLLKSDDLNVVTEENVFESLMAWVQHDSTTREEHLPTLLKLIKLPLLSSEYLIDKVELACGNVPECQPLIMEAVKWHLLPERRSLLFSHRTRPRTSTIGRLLAIGGMDGYKGASNMEMYDPRTNTWTPFMRMGAKRLQFGVAVMQNKLIVVGGRDGLKTLNTVECFDLTSLSWSTLAPMNTHRHGLGVAVLGDGPNSPVYAVGGHDGWIYLNSVERWDACSRTWTIVAPMAGARSTCGVAALRGRLYAVGGRDGGACLRSVECYDPATNHWTNCAPMTRRRGGVSVCAAGSYLYALGGHEAPANTVGGRLACVERYDPVADTWLLLARLSYGRDAIGSCLLGDRIVAVGGYDGVQYLCVVEVYDSGSNVWRKLAPLSTGRAGAAVVAVPPPRNLF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01487820;
90% Identity
iTF_00341442; iTF_00819287; iTF_01430042; iTF_00429147; iTF_00428256; iTF_00113412; iTF_01317412; iTF_00114191; iTF_00112602; iTF_00120645; iTF_00666629; iTF_00044614; iTF_00634606; iTF_00207092; iTF_00143158; iTF_00033020; iTF_00635520; iTF_00795813; iTF_01439143; iTF_00970510; iTF_00971470; iTF_01082576; iTF_00288151; iTF_01438138; iTF_00167004; iTF_00673597; iTF_00008134; iTF_00736713; iTF_00833190; iTF_00406855; iTF_00407689; iTF_01444015; iTF_00171958; iTF_01342326; iTF_00382783; iTF_00948007; iTF_00006377; iTF_00187273; iTF_01081707; iTF_00681755; iTF_01501260; iTF_01336987; iTF_00674396; iTF_01118447; iTF_00111781; iTF_00300363; iTF_00433264; iTF_00432356; iTF_00968144; iTF_01173393; iTF_00622093; iTF_01073713; iTF_01180404; iTF_01179582; iTF_00235957; iTF_01490249; iTF_00236735; iTF_01090901; iTF_00356406; iTF_00835704; iTF_00836685; iTF_00859608; iTF_00150745; iTF_00844487; iTF_01010505; iTF_00027882; iTF_01125578; iTF_00787787; iTF_01220748; iTF_00365038; iTF_00994448; iTF_00806833; iTF_01503089; iTF_00408562; iTF_01341426; iTF_00752181; iTF_00012120; iTF_00942937; iTF_01281465; iTF_00178331; iTF_00290812; iTF_01503996; iTF_00063709; iTF_00026974; iTF_01124703; iTF_00640526; iTF_01302502; iTF_00720464; iTF_00013186; iTF_00072938; iTF_00146544; iTF_00659539; iTF_00412628; iTF_00680693; iTF_01133894; iTF_01463404; iTF_01246039; iTF_00148569; iTF_00772988; iTF_01279388; iTF_00074653; iTF_00411582; iTF_00204442; iTF_01159523; iTF_01157955; iTF_01494403; iTF_01154212; iTF_01176263; iTF_00197453; iTF_01115792; iTF_01402802; iTF_00958035; iTF_01495125; iTF_00195254; iTF_01155478; iTF_01495862; iTF_00840376; iTF_00249791; iTF_01363228; iTF_01361766; iTF_00818429; iTF_01230797; iTF_00250582; iTF_00284660; iTF_00035840; iTF_01416957; iTF_01416004; iTF_00761800; iTF_01437198; iTF_00724047; iTF_01251952; iTF_01083475; iTF_00858687; iTF_01076650; iTF_00648232; iTF_00658525; iTF_01358975; iTF_00834752; iTF_00837681;
80% Identity
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