Basic Information

Insect: Tribolium madens
Gene Symbol: L
Assembly: GCA_015345945.1
Location: JADDYM010000002.1:7885370-7895052[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.034 2.3 8.8 0.5 1 23 71 93 71 93 0.97

2 20 0.096 6.5 7.4 4.8 1 23 99 121 99 121 0.97

3 20 9.8e-07 6.6e-05 23.1 3.2 1 23 127 149 127 149 0.99

4 20 0.00015 0.0098 16.3 0.3 1 23 155 177 155 177 0.99

5 20 0.00021 0.014 15.8 0.3 1 23 199 222 199 222 0.97

6 20 0.026 1.8 9.2 0.1 2 23 249 271 248 271 0.95

7 20 0.1 6.9 7.3 0.2 1 23 305 328 305 328 0.95

8 20 0.0077 0.52 10.8 0.0 3 23 427 447 426 447 0.97

9 20 0.0007 0.047 14.1 2.4 3 23 457 478 455 478 0.91

10 20 0.053 3.6 8.2 0.8 1 23 483 506 483 506 0.94

11 20 0.00078 0.052 14.0 4.6 1 23 569 592 569 592 0.97

12 20 2.5 1.7e+02 2.9 2.2 1 23 638 661 638 662 0.79

13 20 0.0002 0.014 15.8 2.7 2 23 673 694 672 694 0.97

14 20 0.003 0.2 12.1 0.9 1 23 703 725 703 725 0.98

15 20 4.3 2.9e+02 2.2 0.6 3 23 734 754 733 754 0.95

16 20 0.12 7.9 7.1 0.3 1 15 800 814 800 816 0.92

17 20 0.1 7 7.3 0.1 2 23 843 864 842 864 0.90

18 20 0.0028 0.18 12.3 0.3 2 23 873 894 872 894 0.95

19 20 0.0083 0.56 10.8 0.0 1 23 902 924 902 924 0.96

20 20 0.028 1.9 9.1 1.6 1 23 931 953 931 953 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.034	2.3	8.8	0.5	1	23	71	93	71	93	0.97
2	20	0.096	6.5	7.4	4.8	1	23	99	121	99	121	0.97
3	20	9.8e-07	6.6e-05	23.1	3.2	1	23	127	149	127	149	0.99
4	20	0.00015	0.0098	16.3	0.3	1	23	155	177	155	177	0.99
5	20	0.00021	0.014	15.8	0.3	1	23	199	222	199	222	0.97
6	20	0.026	1.8	9.2	0.1	2	23	249	271	248	271	0.95
7	20	0.1	6.9	7.3	0.2	1	23	305	328	305	328	0.95
8	20	0.0077	0.52	10.8	0.0	3	23	427	447	426	447	0.97
9	20	0.0007	0.047	14.1	2.4	3	23	457	478	455	478	0.91
10	20	0.053	3.6	8.2	0.8	1	23	483	506	483	506	0.94
11	20	0.00078	0.052	14.0	4.6	1	23	569	592	569	592	0.97
12	20	2.5	1.7e+02	2.9	2.2	1	23	638	661	638	662	0.79
13	20	0.0002	0.014	15.8	2.7	2	23	673	694	672	694	0.97
14	20	0.003	0.2	12.1	0.9	1	23	703	725	703	725	0.98
15	20	4.3	2.9e+02	2.2	0.6	3	23	734	754	733	754	0.95
16	20	0.12	7.9	7.1	0.3	1	15	800	814	800	816	0.92
17	20	0.1	7	7.3	0.1	2	23	843	864	842	864	0.90
18	20	0.0028	0.18	12.3	0.3	2	23	873	894	872	894	0.95
19	20	0.0083	0.56	10.8	0.0	1	23	902	924	902	924	0.96
20	20	0.028	1.9	9.1	1.6	1	23	931	953	931	953	0.97

Sequence Information

Coding Sequence: ATGAAAATGTTATTCAAGGGAAATAGTAGTCGCTTAGAACTACTGATTGAAAAAATACAGTCGACAAAGGAAGGAGAATTTAAAGTGCCAGTAGCCGAAGATGAAACGGCTGCCAGTTCCGCATCCGGTGGTTCTGGATGTGGCGAAACTCAACCTTTTGACGATGAACAAGTACAGGGAGATCAAGATCAAGATACCAAACCAGGACCATACAAATGCACGGTATGTGGAGAAAATTATTTAAAAGAAAAACTGCTCAGGGAGCACGAACAGAGTCATACTGACCATCTGCAATTCACTTGTGCTTACTGTCCTCGACTTTTCAAGCATAAACGATCAAGAGATCGCCACACGAAGCTTCACACTGGGGATAAAAAATATAAATGTCAGCAGTGCGATTCCGCCTTTTCACGGAGTGATCATCTTAAAATTCATATGAAAACACATGATAGTCGTAAACCATATAAATGTGGTACATGCAATAGGGGGTATAACACCGCCGCAGCACTCTCGTCGCATCAACAAAGTCACTTGAAACAAGAATCTAGGTCCGGAAGTCGCACGAGTGGAGGAAGCACCCCTAGCCCCGGACTTTTCCGGTGCACTCATTGTGCTGAAACTTTCGGAAAACCGGATCTGCTACAGAGTCATATCGCAATGGTCCACAGCGACACCGACTCGTCGCTAAGCCAGACCCCTGAGCCGTTATCAGAATATCAAAACCAAATCGAAGATTTGAAAATAGTTTGCATGTACTGCTCGAAAGAATTCCCCAGTTTGGAGTTGATGTACCAGCACACAAATATCGCCCATCGTGACGTCCCCAACGGTGTTACAACTTCGGTTTCCGTCTCATCTCCTGCAATTCAAAACTCCCCAAAACCGGAAATTTGTCAAAACGGAACACCAACATACGCCTGTGATAGATGCACGATGCAATTAGACTCGATACAAAATTTGAAAAATCATATAAATAATGTACATTGGCGTCCGGCTTTATCTCCTAATCCTGTCAATTTTATGGGGATTGAGAAAAGCTTTTCTCCATTTCAAACCCAACCGACTGACTTGAGCAGAAAGAAAAAAAATGAAGACAGTGCAGAAAAATCGGTCAAAAAGAAGAAAGATCAACATTCACCATCGGCGATAAGTCCGTATGACTCTAATGACAAGCCATGTATTTGCTCGTGCTGCTACGCACAACTGCCAAATTTCAAAAGTTTCCTCCACCACATGGAGTCACATGTAATCTCGTCAAATAATTCCTTACTAGGGTTTTGTCCCGTTTGTGGCGAACCTGGACGTGACCCTGTTTCGTTCACCAATCATATTTTTAGCCATGCCATTGCTCAAGTACCTGGACGTTGTTGTTACACTTGCAAGAAGTCTTTTGAAAGACTAGAAGAGTTACAAAAACACTTATTAGAAGTCCACGTCGTCTCAGTCTTCAAGTGTTCAATCTGTAACGACATTTTTGACACTAAAATATCAATGCAGTTGCATCTGACAAACAAACACAGCGACGAATGCAAACATTTTAAGTGTTACTTGTGCACGAATCAGGTATTTCACGACAGACTTTCGGCAGAATTGCACATTTCCATGAAGCACTACCAACAATTCACACCTTGTGTTGGCACTAATCAACTATTACGGTCGCAATACCAGGAGTTGGATACCAGATTTCGCGACTATAATATGATTTTTCAGTGCACTTTCTGTCACAAGACGTTCAAAGACCAATACTCGCAGTACATACACATTTTGAAGGAGCACAATGAAAGCAAAGAGGGTGAAAAATTCATTTTGGATTCAGCAATGAACCCAAATCCGTCCAGATCGCCTAACTTCATGTTTCCCAAAATAGTAACTCCCGACCACGTGGGTATGGAACCTCCTCTGGAATCGGTCTACACTTGTGATATATGCAACCGCAGTGATATAACTTCCGAATCGGACCTAATAAGCCATAAGAAGCTCCACCACAGCAAAAACAAAATTGGTCCTGTGAGTCTACAATGCGCCTACTGCAACGAGTACTGCAAATCCCGTACCGACTTGGAAAACCACATGAAAACCCACCAAGTAACCTGCGGTAAAGGCAAACACAAATGCAACATTTGCGACGAGATCTACTCCTCCACCCTGACTCTTGCGGATCACAAACTCACCCATTGTAAAATCGTCGAGGGGAATAGTTGTGTCCAATGCAAATCGGTCCTTAGTGACGAGCAGTCCTTCTACAGCCATCAGTTGCAACACAGTGCCAATCCGACAAAACCCAACGCTCAGATTTCCCTCCCGGCAAACTGCATCATCTGCTGTCAGACGTTGCAAACCGATGTGGAGATCAAACTTCATGCCAACTTCCACCTTAAGCACCTCACGCAGAAAGAGTATATGTGCGGGGTTTGCAGCAAGGTTTTTGACAGTCAGAGTAGCCAATCGGCGAACGATATTAACATTGTCGTGTGCAAAGACTGTGCGAAAAGTGAAGACGAGGGGAAAAAAGTGCCGAAACAGTTCGCGTGTATCCAGTGCCCCCAGACTTTTGACAGTGAGAGTGACGTGCAAAACCACGCAGCGATGCATATGTTGAACGAAGGGACGAATCTAGAGTGCCGCTTGTGCAAACAAGTTTTTTCGTCCCCTCTCAAGCTGCAGACACACCTAATCGAGCACAATTTCTACGGGATGAACCAATATAGTTGTTACGTGTGTTCCTCAGTTTTTACAGCCGCGAGCGGGTTGCAGAGTCACATTATCGGGCATGGGTTGGATAGTAGACCCTATGAGTGTTCCCAATGCCAGATGAAGTTCTTCTTTCGGGCCGAACTAGATAATCATAGGTTTGTGCACATCCAGAAGAGCTATCCCATTCATAATGGGGGCGACATCTACGAAAATAAGCCAAGTCCACGCTATAAAATCTGTAAATATTGTTCAAACTCGTATTTGGACAACTCATTTTTCTTAGAACATTTGAATCAGTGTCCCTTTAGGATAAGTCCGAAACGTGAGACTTTCGATACTAATGAAGTAGACAATAATATTAAACAAGAAGTAACAGAAATCACGTCGGAGGAAAAAGATGAGCAATAA
Protein Sequence: MKMLFKGNSSRLELLIEKIQSTKEGEFKVPVAEDETAASSASGGSGCGETQPFDDEQVQGDQDQDTKPGPYKCTVCGENYLKEKLLREHEQSHTDHLQFTCAYCPRLFKHKRSRDRHTKLHTGDKKYKCQQCDSAFSRSDHLKIHMKTHDSRKPYKCGTCNRGYNTAAALSSHQQSHLKQESRSGSRTSGGSTPSPGLFRCTHCAETFGKPDLLQSHIAMVHSDTDSSLSQTPEPLSEYQNQIEDLKIVCMYCSKEFPSLELMYQHTNIAHRDVPNGVTTSVSVSSPAIQNSPKPEICQNGTPTYACDRCTMQLDSIQNLKNHINNVHWRPALSPNPVNFMGIEKSFSPFQTQPTDLSRKKKNEDSAEKSVKKKKDQHSPSAISPYDSNDKPCICSCCYAQLPNFKSFLHHMESHVISSNNSLLGFCPVCGEPGRDPVSFTNHIFSHAIAQVPGRCCYTCKKSFERLEELQKHLLEVHVVSVFKCSICNDIFDTKISMQLHLTNKHSDECKHFKCYLCTNQVFHDRLSAELHISMKHYQQFTPCVGTNQLLRSQYQELDTRFRDYNMIFQCTFCHKTFKDQYSQYIHILKEHNESKEGEKFILDSAMNPNPSRSPNFMFPKIVTPDHVGMEPPLESVYTCDICNRSDITSESDLISHKKLHHSKNKIGPVSLQCAYCNEYCKSRTDLENHMKTHQVTCGKGKHKCNICDEIYSSTLTLADHKLTHCKIVEGNSCVQCKSVLSDEQSFYSHQLQHSANPTKPNAQISLPANCIICCQTLQTDVEIKLHANFHLKHLTQKEYMCGVCSKVFDSQSSQSANDINIVVCKDCAKSEDEGKKVPKQFACIQCPQTFDSESDVQNHAAMHMLNEGTNLECRLCKQVFSSPLKLQTHLIEHNFYGMNQYSCYVCSSVFTAASGLQSHIIGHGLDSRPYECSQCQMKFFFRAELDNHRFVHIQKSYPIHNGGDIYENKPSPRYKICKYCSNSYLDNSFFLEHLNQCPFRISPKRETFDTNEVDNNIKQEVTEITSEEKDEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01568303;
90% Identity: iTF_01480361;
80% Identity: -