Tcas008893.1
Basic Information
- Insect
- Tribolium castaneum
- Gene Symbol
- zfh1
- Assembly
- GCA_000002335.3
- Location
- NC:9064589-9067440[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.00077 3.2 7.4 0.1 21 48 331 358 314 362 0.86 2 4 0.12 4.9e+02 0.5 0.1 16 43 383 410 368 419 0.79 3 4 0.0016 6.7 6.4 0.1 18 43 441 466 437 471 0.90 4 4 2.8e-05 0.12 12.1 0.0 21 48 472 499 469 501 0.91
Sequence Information
- Coding Sequence
- ATGGAAAATAAGACGCTGCAGATCGCTTCCGACTTAGGCATCGAATCAGAAGAAATCGAAATTGTGAGCATAAATACGATCTGCCGGTTGTGTGGCACTCACAACGAGCGTTTGATCGGAATATTCAGCGATGAGGGAGTTGCAAATGATCTCTCGAATAAAATCAATCTGTATCTGCCAGTGAAAGTAGCAGCTTCAGACGAACTGCCTCTGCAATGCTGCTGGAACTGTGCCTCAACGTTGCTGGCCTGGCACGAGTTGGTTGTAACGAGTGTTGAGACAGACCGCAGGTTTAGGAACTTGCAGCTTATTACAGAAAAACACATCGGCGAAGATGCGGCGTTTGATAGCCCCGTCAACCCCCCCAGTGATGACAATGCAGACAATGATGGGATGGAGCCCAAGACCATCGGCACAAGTCTGGATGATTTCAACCAAACTTCGCCAAACCAGGGATCGAAAAGTGCACAAAAATCGCCCAAGAAGAAGAAAAAAGACTCAATCACGTGTTTTCCTCTCCAAGAAACCGAAACACCTCTCGAAACCTACATTACCGACATCGAACAAGAACTAATGGACCCCGAATTGGTCGACGTTCCTGACTACAAAGTAGAAATTGAAACCGATCATCTCCTAACACAGGAAGACGACAAATGTAACGAAATAAAAACGCCAGAGATTAAGCCGGACGAGGAGGAAGAGCGGCCCTATTTCGGGTGCCAATACTGCCCTGCGATTTTCTTCGTTCAGAAAGCGATAGCCGACCACGTGAGAGAAGAACACGGCAAGGAATACAAGAATTGTAAAGTGCATGTGCCAAAGCAAGCGCCGCCGGTAAAGCGGGGAGAGGAGGACCCACATAAGATCGATGAAGAATTAATAAAGGAAGCAAAGGTGGTTGTAGACGGCCGTATTTACTACAACTGCAAGGAGTGCGGAAAAAATCTGCACTCGCCGTACACCTACGTCTGGCATATAAGAATACACACCGGTGAGCGCCCCTTCGTGTGCGACTTGTGTGGGAAACAATTCCGGGTGTCCCAAGGCTTGGTCAGACATTTGCGTGAGACTCACCAAGGTATTAAAAAGTTCCCCTGCGACCTGTGTGGGCGCATGTTCGCCACTCGACGTAACGTGGAAGAACACAGGAGGATTCACACAAACGAAAGACCGTACGTTTGCGACCTCTGTGGCAAGTCTTTCAAGCAGAAGGCGTCACTTTTCGTGCACAAGAGGTCGCACAAGAACCACTTCCCGTTCAAGTGTAGTTACTGCAATCAAGGGTTTCGAACCAAACCGCCTTTACTGGTGCATATCACGAGACATACAGGCGAAAAACCGTACAAGTGTGATATTTGCGGCAGGTGTTTCCGAATTAAGTACGAATTGAAGCGACATAAACTTATACATTCGGATGAGAAGCCGTGGGTGTGCAATGTGTGTGGATTCAGTTTTAGACAGAAGCGGTATTTGAGGAACCACATGAAGTCGAACCATACGCTGGTGGCTTAG
- Protein Sequence
- MENKTLQIASDLGIESEEIEIVSINTICRLCGTHNERLIGIFSDEGVANDLSNKINLYLPVKVAASDELPLQCCWNCASTLLAWHELVVTSVETDRRFRNLQLITEKHIGEDAAFDSPVNPPSDDNADNDGMEPKTIGTSLDDFNQTSPNQGSKSAQKSPKKKKKDSITCFPLQETETPLETYITDIEQELMDPELVDVPDYKVEIETDHLLTQEDDKCNEIKTPEIKPDEEEERPYFGCQYCPAIFFVQKAIADHVREEHGKEYKNCKVHVPKQAPPVKRGEEDPHKIDEELIKEAKVVVDGRIYYNCKECGKNLHSPYTYVWHIRIHTGERPFVCDLCGKQFRVSQGLVRHLRETHQGIKKFPCDLCGRMFATRRNVEEHRRIHTNERPYVCDLCGKSFKQKASLFVHKRSHKNHFPFKCSYCNQGFRTKPPLLVHITRHTGEKPYKCDICGRCFRIKYELKRHKLIHSDEKPWVCNVCGFSFRQKRYLRNHMKSNHTLVA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01480356; iTF_01481146; iTF_01481348;
- 90% Identity
- iTF_01480356;
- 80% Identity
- iTF_01480356;