Basic Information

Insect: Trachelus stipa
Gene Symbol: MBD-R2
Assembly: GCA_036026315.1
Location: JAYRCB010000804.1:40058-47556[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.9e-16 1e-12 48.0 0.3 8 69 538 599 532 607 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.9e-16	1e-12	48.0	0.3	8	69	538	599	532	607	0.92

Sequence Information

Coding Sequence: ATGAAGCAACGATTCGCACGGTCGCGTGGGCCTTGCTACGAGATGCCGCCAACGGGCCCGAGAGGAATGGCGCGCAAATGTTGCGTGCCAAATTGCCAGATCGACGTGCGAGCTGTCCGCGGTAGGGGTATACCATTTCACAAGTTCCCGAAGGACACCATCCTTAGGAGCAAGTGGATTGCTTCTGGTGGTTTCGAACTAAACTTTAAACCCACGCCCGGACAATTTGTCTGCCATAGGCATTTCAAAAAGGCCGACTACGAGACCGCCAAAGGACAGAAGTTCGTATTAAAGAAAGGAGCGGTCCCGTCGGTTTTTGACGATTACGATAATCATCCAGATCCTATGACAATGCCTGTAAAGTCTTCTTCTTATGCTCAGGAAGATTTGGATCTTATTAATTCTGAGATATCTAATTTGGATCATATTGACTCTACAATTTTGACGGATGCACATACACCCAAGTCTGATAGCTGCAGTGAGGCTTACAATTCCAGACCAGCTTCTGCGGCTGATACATTTAATCTGTTTGATACATCGGAGGTGAATGATGGCGaacaaaaattagaaaaggCTGAACTTCCTCTTAAGGACGTTAAGGACAATGTTGATGCAATTGAGAGTAAATTTAATCCTGCTACGAGGCAGCTAGGAATCACTGAACTTGAAGATAAGGCAGAAAGTACAAGGATCGatttgaaaatcatcaaaGAAGAGCCAGAGAAGGTTGCTACGaccgaagagaaaaaaagtgatgaGAATGGAGATTCTAAAGTGAAAGTGATGAGTCGTGGtggcttgaaattttttcctgGTGCTAAGTTAGAGGCTAAAGACTTCAATGAGAAATGGTATTCTGCAAGAGTAGTGGAAACAGACTGGGTGGAGAGGGAAGTGTTGATACATTTCGACAAGTGGAGTTCTAGATTTGATGAGTGGATACCTATGGACAGTTCCAGATTACGAGTACTTCAAATACAGCCAAGcGAGCCTACTTGGACGCTGCCATCTCCGGAAACGAAGATGCGTGAATTCGTCGTCGGCGAGAAGATCCTGGCTACGTGGGCGGATGGCAGAAAGTATCCGGCCAGAGTGAACGCTGTGTTGGGGAACGATAGATACGACGTTCTGTTCGACGATGGATACGCGAAGATCGTCAGGTCCTCGAAGATGACTAAAATCGCTACCACGTCCGAGAAGAAGTCGGTTGAGGGGGATTATATAGGGAGTAAGCAAGAGAGAAGAGACAAGAAGCGGAAGCATACTGTGATGGAGCTGTTTCATACGCATAGCAAGAAACGTCAGAAAGTTGAGGTAGAGCGTCCGATAAAGAAGGAAGAGACTGTGCTCAGTGAGGACGATGGAAAGCTTGATCTGGGCGATTCGGTTCTGGGTACTTCTTATGACTCAGGGTCAGAGGTTCTGCGTGGCTTTGAGAATACCAAACCTAAGATGAAGACGTTCActaagaagaagaggaaggaataCACACGGAACGAAACAGACAACGAAGAAGATGTTGGTCCTGAATGGATCGATGGTGAACCACAAGGCCTTGAGTCTTACATCGTAGATGGCAATGATGGTCCTCGTCGTTCCATCATCGTTCCCGATAAAAGGTTACCACCAGGATGGCAGAAGCATTTTACACAAAGGCGTACAGGCTCCTCAGCTGGCAAATGGGACGTTCTCTTCATACATAAAACAAGTGGAAAGAAGTTCCGGTCGCGAAACGATATCAGAGGCTTCATGGAGCAGCAAGGTCAATTCGACTTTGACCCAGAGAAATTTGACTTTTGCATTCACCGTAAGAAATCAAGCAAGATTAATGTGATGAGATTCAAGCAAGAGACACCTCCGGAAGTTcctaggaaaataaaaactcttcTGCCTAAAACAAAGACTTCTACGCCAGAAAATACATCTTTTCTGTCATTGACTCCAATGACACTTCCGTCAGCTACACCAATGACCCCGGTCGACAGCGGcgCCGTCTTCATAGGTGGCCTTCGCGTGGAAATGGAAGATAGCGCATACAAGTGTCCTAAGGAAGGATGCAACAAGAACTTTCGCAAAGAGAATCTTCTGCAAATGCACATAAAGCATTATCACCCGGAATATTCCAAGTTCCTGGGCTCAACACCGAATGTCGCTGACTTGGCCTACGCCAGGACTATAGGAGAGTCCATCGAGGACATAATACCCAAGAAACCAAACAATTTCCTGGAGAAGATCAACAAATTCGAGAAGAAGAAGGCAGGCCATGAAAAACCTTTGACTCCGGTCGTAGAGTGTGAAACTCCTCGACCAGAAAAGCCTACCATCATTGTCAAGGAGGAGACCAAATTAGAAATCTCGTCGCCTATCTCCACCCAGAGTATCGATATGGATGAGGACAGCAAGAAACGTGAAAGTAATTGCGCCATGTCGCCAGGTACTCTCTTCGACATGAAAGTCAGGGAAGAGAAGACTCAAGTGGGAATTAAAACTCTACTTCCTGTGAGGCCACCATCCACTGTGGAGCCTTTGAAACTTGACAGATCCAAATCTTTGGACGAATCGACTCATTCTGACAAAGGGAAGGTGCAAAAGAAACGACAGCTCTCCGAGTACAGTACCGACTTTCCTGGGAAGTCTAAGAAGAAGCAAGGCATGCAGGAGCTTATGGATGATTATGGGGATTTAGATGACAGTGCTTTGGATGTTGAAGAACCTGCTACTCCAATGTACAGATTCAGTCGCAGAAAATCAGATCCAAAAAGCGACGAGAACAGCCAGAGCAGTCAGCTAAACGATACTCGCCATGAGAAAGGCGATACCCCTAAGGGGGACGCTGCCAAAAgagataatattaatgatgCCGAAgAAGGCGAGGGTgtcatgatgatgatcaaCGGGGAGATGGTGAAAGTTGAACAGCTACGTCGGGAGGAGATAATCAATTGCACCTGTGGATACATGGAGGAAGATGGTCTTATGATACAGTGCGATCTTTGTCTTTGCTGGCAACACGGGCACTGCAACGGCATCGAGAGGGAAAAGGACGTGCCTGAGAAATACGTCTGTTACATATGCAGGCATCCTTACAGGCAGCGACcatcattgaaatattttcatgatcaGGATTGGATCAAGGAAGGAATACTACCAAGTTTACCGAATCGTTCGAAAAATCAAGCCGCCATTAACCAGAGGACCGCTATGTTGAAACGCTCGTACGATTTGGTAGGAGCTCTTTTGCAGATACAGCAGGTTCTCCATAGTCTGCGTGTCAAGATCAACGTGGCACAGAAAAAGGATCATCCAAAATTGTATCTGTGGGCTAAGAACTGGGAGAAGAGCGAGATACCTAAACCGGATACGGATCCGGTGCCTGTAATGGAGATCATAAAGACACCGTTGGATTCAATGGACACAGCTTCCGAAACGTCACACTCTCTGGATCCCAAGGTAGAGTTTAAGGAGACCGTGAAGGAGGATCCGGATAAGAAGTCTATTGCTTCGGATACGGAGCTCATGAAGATCCTTGAAGAAGACAGTACACACTCGGACGAGTCTAAGGTCATCAAGAAGGAAGATACTCAGACGGATGGACACATTCTGTTGGATGCACTCACAAGGACAAGCAGTCCCGAGAAGAAGACGTCCGAGAATCTCAGTGAAAATCCGGATACTCCAAGCGTGGATCTTCCCTCGACGTCTCAGAGTCCACTGGCTGTTTCCACACCGGGAACTGAAAATCTTACACAGGAAACCAGTCCTCTCGCTCAACCTGAGACTGTTCCGCCTATGCAACCTTTTATTCCTGAACCGGAAGCTCCCATAGATCCAGCGGAATGCCGATTAAGATTATTGGAGCACATTGAACACTTTCAGAATCATATCGACTCCCGATTAACCACCATCGAGGCTCAAGTGTGCGCACTGGAAGCCATGGATCCGGATGACCCGACACCCAGTGCGGATGTTCTACCCAGGACCAAGCAAACTGTACAAATGTTACTCAGGGACTTAAATACTGTACGAAAATTAGCTGCACTCTGCTGA
Protein Sequence: MKQRFARSRGPCYEMPPTGPRGMARKCCVPNCQIDVRAVRGRGIPFHKFPKDTILRSKWIASGGFELNFKPTPGQFVCHRHFKKADYETAKGQKFVLKKGAVPSVFDDYDNHPDPMTMPVKSSSYAQEDLDLINSEISNLDHIDSTILTDAHTPKSDSCSEAYNSRPASAADTFNLFDTSEVNDGEQKLEKAELPLKDVKDNVDAIESKFNPATRQLGITELEDKAESTRIDLKIIKEEPEKVATTEEKKSDENGDSKVKVMSRGGLKFFPGAKLEAKDFNEKWYSARVVETDWVEREVLIHFDKWSSRFDEWIPMDSSRLRVLQIQPSEPTWTLPSPETKMREFVVGEKILATWADGRKYPARVNAVLGNDRYDVLFDDGYAKIVRSSKMTKIATTSEKKSVEGDYIGSKQERRDKKRKHTVMELFHTHSKKRQKVEVERPIKKEETVLSEDDGKLDLGDSVLGTSYDSGSEVLRGFENTKPKMKTFTKKKRKEYTRNETDNEEDVGPEWIDGEPQGLESYIVDGNDGPRRSIIVPDKRLPPGWQKHFTQRRTGSSAGKWDVLFIHKTSGKKFRSRNDIRGFMEQQGQFDFDPEKFDFCIHRKKSSKINVMRFKQETPPEVPRKIKTLLPKTKTSTPENTSFLSLTPMTLPSATPMTPVDSGAVFIGGLRVEMEDSAYKCPKEGCNKNFRKENLLQMHIKHYHPEYSKFLGSTPNVADLAYARTIGESIEDIIPKKPNNFLEKINKFEKKKAGHEKPLTPVVECETPRPEKPTIIVKEETKLEISSPISTQSIDMDEDSKKRESNCAMSPGTLFDMKVREEKTQVGIKTLLPVRPPSTVEPLKLDRSKSLDESTHSDKGKVQKKRQLSEYSTDFPGKSKKKQGMQELMDDYGDLDDSALDVEEPATPMYRFSRRKSDPKSDENSQSSQLNDTRHEKGDTPKGDAAKRDNINDAEEGEGVMMMINGEMVKVEQLRREEIINCTCGYMEEDGLMIQCDLCLCWQHGHCNGIEREKDVPEKYVCYICRHPYRQRPSLKYFHDQDWIKEGILPSLPNRSKNQAAINQRTAMLKRSYDLVGALLQIQQVLHSLRVKINVAQKKDHPKLYLWAKNWEKSEIPKPDTDPVPVMEIIKTPLDSMDTASETSHSLDPKVEFKETVKEDPDKKSIASDTELMKILEEDSTHSDESKVIKKEDTQTDGHILLDALTRTSSPEKKTSENLSENPDTPSVDLPSTSQSPLAVSTPGTENLTQETSPLAQPETVPPMQPFIPEPEAPIDPAECRLRLLEHIEHFQNHIDSRLTTIEAQVCALEAMDPDDPTPSADVLPRTKQTVQMLLRDLNTVRKLAALC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00291537;
90% Identity: iTF_00294526;
80% Identity: iTF_01473972;