Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: -
Assembly: GCA_030247195.1
Location: CM058070.1:422451710-422453362[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00066 0.068 15.7 1.6 1 23 84 106 84 106 0.99

2 13 7.5e-06 0.00076 21.8 0.9 2 23 158 179 157 179 0.97

3 13 0.6 62 6.4 0.3 5 23 220 238 217 238 0.93

4 13 1.9e-07 1.9e-05 26.8 0.3 1 23 244 266 244 266 0.98

5 13 1.4e-07 1.4e-05 27.2 2.4 1 23 272 294 272 294 0.99

6 13 2.3e-07 2.4e-05 26.5 1.2 1 23 300 322 300 322 0.98

7 13 0.058 5.9 9.6 0.2 2 21 325 344 324 345 0.94

8 13 3.6e-06 0.00037 22.8 0.3 3 23 355 375 354 375 0.97

9 13 2.6e-06 0.00026 23.2 5.2 1 23 381 403 381 403 0.98

10 13 0.0096 0.98 12.0 1.4 1 23 409 431 409 431 0.97

11 13 1.2e-07 1.2e-05 27.4 1.2 1 23 437 459 437 459 0.98

12 13 5.1e-06 0.00052 22.3 1.8 1 23 465 487 465 487 0.99

13 13 2.1e-06 0.00022 23.5 1.8 1 23 493 516 493 516 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00066	0.068	15.7	1.6	1	23	84	106	84	106	0.99
2	13	7.5e-06	0.00076	21.8	0.9	2	23	158	179	157	179	0.97
3	13	0.6	62	6.4	0.3	5	23	220	238	217	238	0.93
4	13	1.9e-07	1.9e-05	26.8	0.3	1	23	244	266	244	266	0.98
5	13	1.4e-07	1.4e-05	27.2	2.4	1	23	272	294	272	294	0.99
6	13	2.3e-07	2.4e-05	26.5	1.2	1	23	300	322	300	322	0.98
7	13	0.058	5.9	9.6	0.2	2	21	325	344	324	345	0.94
8	13	3.6e-06	0.00037	22.8	0.3	3	23	355	375	354	375	0.97
9	13	2.6e-06	0.00026	23.2	5.2	1	23	381	403	381	403	0.98
10	13	0.0096	0.98	12.0	1.4	1	23	409	431	409	431	0.97
11	13	1.2e-07	1.2e-05	27.4	1.2	1	23	437	459	437	459	0.98
12	13	5.1e-06	0.00052	22.3	1.8	1	23	465	487	465	487	0.99
13	13	2.1e-06	0.00022	23.5	1.8	1	23	493	516	493	516	0.97

Sequence Information

Coding Sequence: ATGTTGGGAAAATATGGTGAAACACCGGAAAGTGACCGAAACCGAAATCAACCGCTGCCGATGGTACCGCCTCCACTCTATCCGGCACCATCCACAACATCCATAGTGAATAACCGATCAAACGAAACAACAGTAGCTACTGTGGTAAATTCACTGCCAACCATGCTTGGCAAAAGTGTGTCCGCTGGCCCGTCATCGACCGTAGTGGCAAGCAGTTTGGAATCGAGCGTTAAGCAACTTACCCCGCAATATCAGTGTCAGCTTTGTCTCAAGTGTTTCGAGAATGTGTCCGCTCTGTCGTTGCATCTAAATTCACACGAGCAAGAGTATCGCGGTACGATGAACTACAATGGACAGATTACTCCCGCACATACGATCAAAACGGAACCGCAATCGTTTCATCTGGTAGCACCACCGAACTACCCGGGTACCGTGCTGCAGGGTTTTCAGATCGTCACCAGCTCCGGCCAGGTGTGTCAAATTTGTCAGAAGGTTTTTAGTTCCGCTGAACAGTTTCATGCTCATATGAAGATTCATGAAAACGAATCCCGATATCGAGCATGGTATCAGTCTAATTCGGCTGGTGCGGCTCCTGTACAACCACCCAAGGAACCAGAGGTAGTAGAGGAAAACGATGGAAAACCGATCGACTGTATTGTGTGCCATAGCAAATTTCAAACCGCTGCACTATTGGCCGTGCATCTGCGCGAGCATAGCACTCAGAAACCGTACGTTTGTACCATTTGCGGAAAAGGTTTCATTCAATCTAACAATCTTTCTACACACATGAAAGTGCACTCTGGACAGAAACCTTTCAAATGCGATATCTGCAATAAAAACTTCAGCCAGTCCAACAATCTAAAGACACACGTAAGGACCCACACGAACGAACGACCCTACGCGTGTGCCATTTGTGAGAAACGGTTCAACCAGAAAAACAATCTGACCACACATATGCGAACCCACTCGCTCGTTTGTAAAGTCTGTCGGGTTCAGTTTCAGCATCCGACGGAACTATCCAATCACGTACGGATTTGCTATGCAGATCTTAAGCCAAACATTTGTACCGTGTGTAACAAGGTGTTCGTCAACAACGACGAACTGACGGATCACATGAAACAGCACAATCAGGTTAAACCACACAAGTGTCAGATCTGTCTAAAAACTTTCACCCAGTCGAACAATCTGAAAACTCACATGAAAACTCACATCTTCCAAGACCCCTTCAAATGTTCCTTCTGCTCGCGTTCGTTCCAGAATGACGAAGAATTCGCTCGTCATTCACTGGTGCATTCCTCCCCGAAACCGTTCAACTGCCCTTACTGTGGCAAACAATTCATTCAGTCAAACAATCTGAAGACACACGTACGAACCCACACTGGCGAGAAACCGTACAAGTGCTACATATGCGACCGATTGTTTAACCAGAAGAACAACCTCAACACCCACTTGCGCATTCATCAGGGGCTTAAGCCCTATCAGTGTACGGTTTGCGAGAAGCGGTTCAATCAGAGTAACAATTTGAACAAACACATTTATAAGGTTCACTGTCACGAGAAGGCAGACCAGCCCATCGGTACTGCTTCGACAGCTGCTGCTACCATTGGGTCAGCAGCAGACGTTCCGCTGGATGGTGTCGGAACGGCCAGCTGA
Protein Sequence: MLGKYGETPESDRNRNQPLPMVPPPLYPAPSTTSIVNNRSNETTVATVVNSLPTMLGKSVSAGPSSTVVASSLESSVKQLTPQYQCQLCLKCFENVSALSLHLNSHEQEYRGTMNYNGQITPAHTIKTEPQSFHLVAPPNYPGTVLQGFQIVTSSGQVCQICQKVFSSAEQFHAHMKIHENESRYRAWYQSNSAGAAPVQPPKEPEVVEENDGKPIDCIVCHSKFQTAALLAVHLREHSTQKPYVCTICGKGFIQSNNLSTHMKVHSGQKPFKCDICNKNFSQSNNLKTHVRTHTNERPYACAICEKRFNQKNNLTTHMRTHSLVCKVCRVQFQHPTELSNHVRICYADLKPNICTVCNKVFVNNDELTDHMKQHNQVKPHKCQICLKTFTQSNNLKTHMKTHIFQDPFKCSFCSRSFQNDEEFARHSLVHSSPKPFNCPYCGKQFIQSNNLKTHVRTHTGEKPYKCYICDRLFNQKNNLNTHLRIHQGLKPYQCTVCEKRFNQSNNLNKHIYKVHCHEKADQPIGTASTAAATIGSAADVPLDGVGTAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01462921; iTF_00949464; iTF_00949010;
90% Identity: iTF_01462921;
80% Identity: iTF_01462921;