Tcon014695.2
Basic Information
- Insect
- Tipula confusa
- Gene Symbol
- Rfx2_1
- Assembly
- GCA_963556175.1
- Location
- OY744475.1:201789625-201799376[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 3.9e-37 4.5e-33 115.0 0.1 3 78 160 235 158 236 0.97 2 2 2.6 3e+04 -3.0 0.0 24 37 583 596 567 604 0.65
Sequence Information
- Coding Sequence
- ATGGTGCATCTTCCTGCATTGGTGGCAACGTTTCTTCGATGTTCATTCGAACGCACTATGTTCTTCAGCCAAGCAATTGAAACACCTGGAATTGTCGtgtccTCTCAGGACTCAGTGCCGCCACATTCATATCACGTACAATATGTTGATTCCGATTTATATTCAGCAACAGGACAATCACAAACACAAATGGCATATCCTGTATACACTGTGGGTGACTATTCAACAAATGGCCAGCAATATTATGCATCAACTGGTAATTATGGTAGCTCATCGTCAAATAATAGTTCGAGTACGTATAGCATTGTACCTGTAGATGATACAATATTAACGTCACAACCGCATGACTCGCCGCAAAGTATTTCGGCGgagGTAGGTTATATCCAAGGTCCACACTCGGGGTCTAATGCTAACAATATTTCCGCTCCTGAAACTGAATCAACTCCTAATTTATCGCATGCGACACGAGTTTCCCCGGCTACGgttGCATGGCTTTTGGATAATTACGAAACAGCCGAGGGTGTTAGTTTACCCCGATCCACCCTTTACAATCATTATATGCGACActgcaatgaaaataaattagacgCTGTGAATGCGGCTAGTTTTGGTAAATTAATACGATCTGTATTTACGGGATTGCGAACTCGTCGTCTTGGTACTCGGGGTAATTCAAAATATCATTATTATGGCATACGTGTTAAACCTGGATCACATTTAATGTCGGCACTCGATGAAAAACAACCACAAAATGGTGCCGCCACATCCAATTCCAATATAAACCATACCACGGTAACAAGAAATAATCGAAAATCAGGTTCTAAACCAGAAACGTATGAAGCATGTTCACAGTATTTAGGCGATGGGTCACGAGCCATTCCTTTGTTTCCTTCCATTGATATAACGCAACCATTCCCGGATGAAATTACACTCGAGGATGTTGATACATTGCGTTCAATATATCGTGAACATTGTGAAGCATTTCTCGATGccatattaaatttagaatttagtacGGTTGAATCGTTGTGGCGCGAATTTTGGCGCGCTCAGGATAATATAAATGGAGACGAGTGTGaagaggaaaaatatttaagcaaatcaAAACTCTATGTACTATGCCAATGCGAtgccattcaaaattttatacgGCAAGTTGATTTGGCATTCTATCAAAATGTGGTCGAAGTTCTAATACCAGACGTGTTACGACCAATTCCAAGTTCATTGACCCAGGCGATAcgaaacttttcgaaaaatttagaaaattggcTAACGACTGCAATGGCTGGATGCccgaataaaataatacaaataaaactatCGTCGGTCCAGGCTTTTGGTCAAACTTTGCGACGATACACATCACTTAATCATTTGGCACAGGCGGCCCGAGCCGTGCTACAAAATAGTTCACAAATTACTCAAAtgttgaacgatttaaatcgaGTCGATTTTCACAATGTACATGAACAGGCATCGTGGGTATGCCAATGTGATACAAATACGGTACAAAGATTAGTGAATGATTTTAAAGCAGCACTTCAGCAACAAAACACATTAGAACAATGGGCGTCATGGTTGCGACTTGTTGTAGATACTGCGCTCGAAGAGTATCAAGGTAAACCGAGTTATGCGACTGCTGCACGACAATTTCTGCTTAAATGGAGTTTCTACTCGTCAATGGTTATACGTGATTTAACGCTAAGATCAGCCGCTAGTTTTGGCAGCTTTCATTTGATACGGCTGCTCTACGACGAATACATGTTTTTCATTGTCGAACATAAGGTAGCTCAAGCAACGGATACAAAACCAATTGCTGTTATGGGAGAATTCAACAAGATTTCGTTTCCATTTCAGCATTTAAACGATATGCATCAACAGGATAATCTTATGTTCCCAAatgatatacatttaaaaattgaaccaGAAACAAAACGGATGCGTAGTTAG
- Protein Sequence
- MVHLPALVATFLRCSFERTMFFSQAIETPGIVVSSQDSVPPHSYHVQYVDSDLYSATGQSQTQMAYPVYTVGDYSTNGQQYYASTGNYGSSSSNNSSSTYSIVPVDDTILTSQPHDSPQSISAEVGYIQGPHSGSNANNISAPETESTPNLSHATRVSPATVAWLLDNYETAEGVSLPRSTLYNHYMRHCNENKLDAVNAASFGKLIRSVFTGLRTRRLGTRGNSKYHYYGIRVKPGSHLMSALDEKQPQNGAATSNSNINHTTVTRNNRKSGSKPETYEACSQYLGDGSRAIPLFPSIDITQPFPDEITLEDVDTLRSIYREHCEAFLDAILNLEFSTVESLWREFWRAQDNINGDECEEEKYLSKSKLYVLCQCDAIQNFIRQVDLAFYQNVVEVLIPDVLRPIPSSLTQAIRNFSKNLENWLTTAMAGCPNKIIQIKLSSVQAFGQTLRRYTSLNHLAQAARAVLQNSSQITQMLNDLNRVDFHNVHEQASWVCQCDTNTVQRLVNDFKAALQQQNTLEQWASWLRLVVDTALEEYQGKPSYATAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFFIVEHKVAQATDTKPIAVMGEFNKISFPFQHLNDMHQQDNLMFPNDIHLKIEPETKRMRS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01457076;
- 90% Identity
- iTF_01458084;
- 80% Identity
- -