Tpel014536.1
Basic Information
- Insect
- Tinea pellionella
- Gene Symbol
- L
- Assembly
- GCA_948150575.1
- Location
- OX411245.1:5527721-5531277[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.54 30 5.3 5.8 1 23 3 25 3 25 0.97 2 16 1.4e-06 8e-05 22.9 3.1 1 23 31 53 31 53 0.99 3 16 2.2e-05 0.0012 19.1 0.1 1 23 59 81 59 81 0.98 4 16 0.0013 0.074 13.5 0.6 2 23 94 116 93 116 0.95 5 16 3.6 2e+02 2.7 0.1 9 23 147 162 143 162 0.93 6 16 0.26 14 6.3 0.0 3 23 224 244 223 244 0.97 7 16 0.066 3.6 8.2 0.1 2 23 259 280 258 280 0.87 8 16 0.00071 0.039 14.4 0.3 1 23 288 311 288 311 0.94 9 16 0.028 1.5 9.4 0.1 1 23 316 339 316 339 0.92 10 16 0.051 2.8 8.6 0.0 1 23 399 424 399 424 0.91 11 16 0.0006 0.033 14.6 0.0 2 23 478 499 477 499 0.96 12 16 0.047 2.6 8.7 0.0 1 23 507 529 507 529 0.98 13 16 1.4 76 4.1 0.8 2 23 537 558 536 559 0.93 14 16 0.75 41 4.9 0.3 1 23 633 655 633 655 0.94 15 16 0.003 0.16 12.4 0.1 1 20 663 682 663 685 0.95 16 16 0.16 8.8 7.0 0.6 1 23 692 714 692 714 0.93
Sequence Information
- Coding Sequence
- ATGCCATTTCGTTGCGAATTCTGTTCACGGCTCTTCAAGCATAAGAGATCCCGAGATCGTCATGTTAAACTGCATACTGGAGATCGCAAGTACCGATGCGCACACTGTGAAGCTGCATTTTCACGCAGTGATCATCTGAAAATCCACATGAAAACGCATGACAATCAGAAACCGTTTCAATGCACAGTATGTAATCGTGGTTACAACACTGCAGCCGCTTTGACATCACATATGCAGGGTCATAAAAAAGATTGTGATCCTGAACGAAGACGATCCATGCGTTGCTTGCGTTGTGGAGATTCTTTTAGGAGACTCGATTTATTGCAAACACATATGACCAGCGTACACGGTGTCGAAGCGCCTACATTAACACCCCCTAGAAGAGTGGCCTCTCATCCTGCCCCTACTTTACTAGCCTGTATATATTGTACCAGGGATACTTTTACTACTATGGAACAATTACAACTCCATGTCAGAGCGGCACATTCAGCACTTCTAAATGGCGAATCAATGTCTGAACCTCCACGTATATCCCCATCTCTACCTCCACCCGAAGCGACACCCACAGATTTAAGTCGTAGAAGTTCTGAAGGACCGCCCGTTAAACGGCCCCGATCGGGCTCTGGCTCCAGAACTCCGCAGAAAACGTTATCTCCGAACACACTTCTTTGTAATCAATGTGATGCTGCTCTTCCTGATTTTGAAGCTTTTCGGGCACATCTAAAAGGTCATCTAGAAGAAAATAATGGAGAAACGGAAAGAGAGAGTCCAACACCATGCCCCCATTGTGGTGCAACATTCGCTGATATAACTGCGAGTGAACGTCACTTGGCTGCACATTATTTGGCAGCATCATGTGAATATACTTGTCACAGTTGTGCTCGCAGTTTTCCTGCTCCTGATGATTTACAGAAACATTTACTAGATCTGCACGCTCATCATCTTTATCGATGTTCACTTTGTAAAGAAATCTTTGATTCTAAAGTAGCTATTCAGGTGCACTTCGCAGTAGCTCACAGTGGAGAAAATAAAGTTTGGATATGTCGTGGCTGCGGAGCTGGTGGAGGTACTTTACGATCAGAAGCTGAAGGGACAGCTCATGTTCGAGCACGTCATGCAGCAAGGCGATGTGCTTGTGGAGCGGTGTTAGCTGGAGAACGAGCTCTCAGAGCTCATACTGCTGCACACGTACACTATAGATGTCCGGCACCGGCATGCGCTGATACATTTGCCGTGCAATATTTACTCGAAAGGCATATGCAATCACAACATTCATTGCCCTTACATCAGGGGTTAAATGGAGAATCTGGACGTGTGAAGCGTTTGGATAACAACAATGTGACAGATGGAGGAGAAGGTGCTTGTTCTCCTTGTACTATTGGTACGGGAGTCGGTGAAGAAAGACGACGTAAGAATGGTGCAGTTGCTCTGCAATGTGCATATTGCGGTGAAAGAGCAAGAACTAGAGCAGAATTAGAAGCCCATACGAGAGCCCATTCTGGCGCCTCCGCGGCAAGGCACAAGTGTCTTATATGTGATGAGGTTCTACCCTCTGCTGGCGTCCTAGCTGAACATAAACTTACGCATTGCAAGGTTGTAGCCGGAGATACTTGTGCCAGATGTCGCGCCCGGTTAGTTTCCGAAGAATCTTTCTTAACACACATGGCTCGTCATCATCCGGCACTTCCCGCGCCGTGTGTCGTCTGTCGTCAGACACTCGCTTCTGAAGCGGAAGCTCGCCTACATGCACGTTTCCACCTTCGGCCCACCGGCGACGAACAACGCTGTGCTATATGCCTTCGCCCCTTAACAGAAGGGGAGGGTGGAGAGGGTGCTCGCGCCTGTAGTGCTTGCTATGCTCGTCATGCAGCGCCGGTACCGCCCCCACCGGCAGAACATGACTGCAGACTGTGTCGACGAGCACTCGGCTCTCCGACTAGATTACAAGCGCATCTAATTGAACACACGTTCGCCGGTATGGGAGCGTTCACATGTTATCTATGCTCGGCGGTGTTCACGAGTGCCGCCGGTCTACAACGTCACCTTCCGGAGCATGCGGCTGCTACGCGACCTTATGACTGCGGACGTTGTGGCCTAAAGTTCTTCTTCCGCGCCGAACTCGATAATCACTCATTTGTGCACCTCGAAGAAGCAGAAATCGCTCAGAGAGCATTTTATGAAGCGTACGCTCGAGGTGCGGCGTGGGCCGCTTTAGCTCCACCAGAAAGTGCATTACCACCTCCTCTTATACCGCCACCGATTACGACAAATGAAGCTGAAACGGATCTAACAGTAAAAACCGAGCCGGAGATCAAGGAGGAACGTGTTAATGATGAGTATATAGAAGTGTCGTCACCGCCACCGCCACAGTCCCCTCCTCCGACGCTGTCTCCTTCGACAGCAGCTCCAGTCGTCAAACAAGAGACGAATGATGATGAGTAG
- Protein Sequence
- MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKKDCDPERRRSMRCLRCGDSFRRLDLLQTHMTSVHGVEAPTLTPPRRVASHPAPTLLACIYCTRDTFTTMEQLQLHVRAAHSALLNGESMSEPPRISPSLPPPEATPTDLSRRSSEGPPVKRPRSGSGSRTPQKTLSPNTLLCNQCDAALPDFEAFRAHLKGHLEENNGETERESPTPCPHCGATFADITASERHLAAHYLAASCEYTCHSCARSFPAPDDLQKHLLDLHAHHLYRCSLCKEIFDSKVAIQVHFAVAHSGENKVWICRGCGAGGGTLRSEAEGTAHVRARHAARRCACGAVLAGERALRAHTAAHVHYRCPAPACADTFAVQYLLERHMQSQHSLPLHQGLNGESGRVKRLDNNNVTDGGEGACSPCTIGTGVGEERRRKNGAVALQCAYCGERARTRAELEAHTRAHSGASAARHKCLICDEVLPSAGVLAEHKLTHCKVVAGDTCARCRARLVSEESFLTHMARHHPALPAPCVVCRQTLASEAEARLHARFHLRPTGDEQRCAICLRPLTEGEGGEGARACSACYARHAAPVPPPPAEHDCRLCRRALGSPTRLQAHLIEHTFAGMGAFTCYLCSAVFTSAAGLQRHLPEHAAATRPYDCGRCGLKFFFRAELDNHSFVHLEEAEIAQRAFYEAYARGAAWAALAPPESALPPPLIPPPITTNEAETDLTVKTEPEIKEERVNDEYIEVSSPPPPQSPPPTLSPSTAAPVVKQETNDDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01545077;
- 90% Identity
- iTF_01453463;
- 80% Identity
- -