Tmon042401.1
Basic Information
- Insect
- Timema monikensis
- Gene Symbol
- -
- Assembly
- GCA_902151445.1
- Location
- CABFVZ010002805.1:49755-60728[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 4.3e-05 0.009 18.5 0.5 2 23 84 105 83 105 0.94 2 17 1.9 4e+02 3.9 3.0 1 23 111 134 111 134 0.96 3 17 0.0049 1 12.0 1.2 2 23 139 160 138 160 0.96 4 17 0.00061 0.13 14.9 0.1 1 20 168 187 168 189 0.94 5 17 0.00011 0.022 17.2 0.4 1 23 197 219 197 219 0.94 6 17 0.0014 0.29 13.7 1.7 1 23 225 247 225 247 0.95 7 17 0.00011 0.023 17.2 0.9 1 19 253 271 253 275 0.96 8 17 0.027 5.6 9.7 1.4 1 23 281 303 281 303 0.98 9 17 0.0012 0.25 14.0 2.8 1 23 694 716 694 716 0.95 10 17 0.091 19 8.0 4.5 3 23 726 746 725 746 0.95 11 17 0.00036 0.075 15.6 2.2 1 23 752 775 752 775 0.97 12 17 1.4e-05 0.003 20.0 4.3 1 23 779 802 779 802 0.96 13 17 2.2e-05 0.0045 19.5 0.2 1 20 810 829 810 831 0.94 14 17 0.005 1 12.0 0.4 1 23 839 861 839 861 0.93 15 17 0.0025 0.51 13.0 1.8 1 23 867 889 867 889 0.95 16 17 2.3e-05 0.0048 19.3 0.4 1 23 895 917 895 917 0.95 17 17 0.019 3.9 10.2 1.8 1 23 923 945 923 945 0.98
Sequence Information
- Coding Sequence
- aTGTACAAgctaaaaacacacacactaatAAAAAGGCGGCGCAACAGCAGAAACGCAAGTTTCCGGCCAAAAGACGGAAAACGCAAAGGTTCTGTCTTCAAACCACCCAAGATCCTGCCCATTTCCCGTGCAAACACTGCGATGAATACTTTACACAAGAACAATTACTCCGGCGTCATACCAAACTCCACAATATTGCAACACCACCTGGAAAGCCACACAGACAAGACTGACGCCAAAAATGCTTTAATGTGTAATATTTGCGGTAAGAAATACAAGAAAAGCGGTAGTTTGACTAAACACGCCCTGGAACACGAAGGTAAGGGGCGGTTCAAATGCAGGCTATGCAGGGAGATTTTTCCTACGGATTGTGAGCGCACCAAACACCGGGAAAAGGTCCACGAAAAACCGTGGAAATGCGACTTGTGCCCTCACACGTTCATGTCCAAGGATAAACTGGATCAGCATGTCAAATGGCATGTAAATAAGGAGAGTGAAGTGTTTGTCTGCAATGTATGCTCGAAAGAATTCAAGCTCAAAGTCAACCTTAAGATCCACGTGGAAAGTCGCTGTGGCACAGACCCTCAGCACGCATGCAAGGATTGTGGGAAAGCGTTCATGACACGTGGTACTCTCATTACCCACGCTCTCCTTCACACGGGAGAGAAAACGTTCCTATGTCGGTTCTGTGGGAAGAGCTATCGTCTCAAGGTGGAGATGCAACGCCACGAGCGCTCACACACAGGCGAGAAACCGTTTGTCTGCAAAGTGTGCGGTAAGGCGTTCTCTCATCGGGAGAGTCTCGTCACCCATGATACATTGCACACAGGTATTCGGCCGTACATGTGCGAAGCTTGTGGCTCTACCTTCTCCTGTATCGGTAACCTCATCAAACACAGGAAGACCCACCGTAACAAGTGCGGCCAGAATGCTGTGACTGGCGTTAACAAGACGGATAAAGAAAGGGCGTCTGTTGCCTCCACCTCAAAGTTGCATCTACCCGAGAAACCCAAGGTCTCTCTCGAGAAGGTCTTTCAAAAATCTACCCCAACACCTGCTACGCTCCAGAGATCTAGCGAGCTGCCCGCACCTCCGGTTGTTGGTTACTACAACAGCTACAAGCAGCCGCCTTACGAGGAGAACCACCATTGGGTCAATCCACTGCCGATGTGCAACGAGGCGGCAAATGAAAGACTTCATCCTTCCACGGAGCTACAGGGGGTCACAGAGTTAAGTAGGAAGAGttCACATCTCTATTGGGGTGGCAGCAACAGTATTATTGGTACCCACCAAGAGTCGGCGCAGACCTCCTATGCACCATACAATAAGGACATGTGCTATGATACGGTCCAAGCCCGTATTTTCTACCCGGCTGCCTCAGAAGTCCACAAACCAGCAGGGAACTTTTTCCAAAACTTGGACGCAGACAAACCTCCATACTGTCACAGGTTTCATGACCCTGAGAGAGATAAACTGCCTTACAGTTACAAAATCCACAACATGGACAATGAAGATTACAATGAAGACACTAAAACCAAAGGTGTAGACAGTACTGaaagtgatgatgataatgataactTTGATAAGACTGATGTTGACtcttataaaaacaattctgATTTCAATCTAAATGATGAGCTTTATGAGGaaacaaatttgtattcaaaagACCAAGAAGTTGGGAATGATGATACAAGCTCGGTGAAGAAACCTATCCGTGAACGGAAACAAAAATTTCCGGTGAAATGTAATGTACTTAAATCGGAGAATATTGAGGAGTTATCTCAGGGAAATTTAAATGCTTTACCTTGCAAACAAAATGATTCCTTAAAACCACATAAAAGTAATTTGTGTAAATTAGAGGAAACAATACTAGACAGTTTTTCTAGTTGCCAATTTGATAGAAAGTTTGATTCTAAACCAGATGTACAAGAACATGTGTTGGTTCACACTACTTCAAGTGGCACGACAAACAACATTCAGCAAGTTAACTCGGTTTCCGAAGATGACGAATCTTTAGACAAGAGGTTGAGTCGGTATTTATTAAAGACTGGTGGAGATTCAGTCCCAAATAAAAAGTTCCTTTGTCAGTACTGCAACAAAGAATTCAGTTTTATATCGCGGCTAAACCGCCACCGGAAACTACACGTTGAAGAAGAAAAGGAAACTCCTTTGTGCCGGTTCTGtggtaaaaaatactttaacaaaGCGTGTCTTAGGAAACACGAATCTCAACATAAAGGTGCCGGAGTTTATCAATGTCGAGAGTGCAAAGAAGGATTCGAAAGTAAATCAGATTATCGGCAGCACAGATTAAAACGGCATGGGAGGGAACACGTTTGCTCGAGCTGCCATCGCACATTCTCCAATGCCAGTAATTTGAGGATCCATATGAACAACAAACACACATATCACACACCCGAATCCTACGCATGCCAGCTATGCggtaaacaatttaaacaaaagggTAATTTAAAAGTCCACGTGGACAGCCGTTGCGGTTCTGAGCCGCGCCACGCTTGCTCTGTCTGCGGTAAGGCCTTCATGAGCGTCGGATCGCTCAGCACGCACTTCCTCCTCCACACGGGTGAGAAAACGTTCCTGTGCCGGTTCTGCGGGAAGAATTACCGTCTCAAGGTGGAGATGCAGCGCCACGAGCGTACTCACACGGGAGAGAAACCGTTTGTCTGTAAAGTGTGCGGTAAAGCGTTCGCGCATCGAGAGAGTCTAATCACCCACGCCACACTTCATACAGGTTTAAGACCGTACATGTGCGAGTCTTGCGGGTCTACTTTCTCATGTATAGGTAATTTGATAAAACACCGACAGACCCATAATAGACGTTGCCAAATAGCTGCAAGATGA
- Protein Sequence
- MYKLKTHTLIKRRRNSRNASFRPKDGKRKGSVFKPPKILPISRANTAMNTLHKNNYSGVIPNSTILQHHLESHTDKTDAKNALMCNICGKKYKKSGSLTKHALEHEGKGRFKCRLCREIFPTDCERTKHREKVHEKPWKCDLCPHTFMSKDKLDQHVKWHVNKESEVFVCNVCSKEFKLKVNLKIHVESRCGTDPQHACKDCGKAFMTRGTLITHALLHTGEKTFLCRFCGKSYRLKVEMQRHERSHTGEKPFVCKVCGKAFSHRESLVTHDTLHTGIRPYMCEACGSTFSCIGNLIKHRKTHRNKCGQNAVTGVNKTDKERASVASTSKLHLPEKPKVSLEKVFQKSTPTPATLQRSSELPAPPVVGYYNSYKQPPYEENHHWVNPLPMCNEAANERLHPSTELQGVTELSRKSSHLYWGGSNSIIGTHQESAQTSYAPYNKDMCYDTVQARIFYPAASEVHKPAGNFFQNLDADKPPYCHRFHDPERDKLPYSYKIHNMDNEDYNEDTKTKGVDSTESDDDNDNFDKTDVDSYKNNSDFNLNDELYEETNLYSKDQEVGNDDTSSVKKPIRERKQKFPVKCNVLKSENIEELSQGNLNALPCKQNDSLKPHKSNLCKLEETILDSFSSCQFDRKFDSKPDVQEHVLVHTTSSGTTNNIQQVNSVSEDDESLDKRLSRYLLKTGGDSVPNKKFLCQYCNKEFSFISRLNRHRKLHVEEEKETPLCRFCGKKYFNKACLRKHESQHKGAGVYQCRECKEGFESKSDYRQHRLKRHGREHVCSSCHRTFSNASNLRIHMNNKHTYHTPESYACQLCGKQFKQKGNLKVHVDSRCGSEPRHACSVCGKAFMSVGSLSTHFLLHTGEKTFLCRFCGKNYRLKVEMQRHERTHTGEKPFVCKVCGKAFAHRESLITHATLHTGLRPYMCESCGSTFSCIGNLIKHRQTHNRRCQIAAR*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445031;
- 90% Identity
- iTF_01447784;
- 80% Identity
- -