Basic Information

Insect: Timema monikensis
Gene Symbol: -
Assembly: GCA_902151445.1
Location: CABFVZ010000778.1:177858-192386[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.4e-05 0.0028 20.1 1.0 1 23 206 228 206 228 0.96

2 18 0.01 2.1 11.0 3.3 1 20 234 253 234 256 0.93

3 18 5.4e-06 0.0011 21.3 1.2 1 23 262 284 262 284 0.99

4 18 7.1e-05 0.015 17.8 3.5 1 21 290 310 290 312 0.94

5 18 0.00014 0.029 16.9 4.7 1 23 318 340 318 340 0.99

6 18 2.8e-05 0.0058 19.1 5.3 1 23 346 368 346 368 0.97

7 18 1.4e-06 0.00029 23.2 3.9 1 23 374 396 374 396 0.96

8 18 1e-07 2.2e-05 26.7 2.7 1 23 402 424 402 424 0.98

9 18 7.8e-05 0.016 17.7 6.7 1 23 430 452 430 452 0.97

10 18 7.7e-05 0.016 17.7 5.7 1 23 458 480 458 480 0.97

11 18 6.4e-07 0.00013 24.3 2.9 1 23 486 508 486 508 0.98

12 18 9.5e-06 0.002 20.6 7.8 1 23 514 536 514 536 0.98

13 18 3e-05 0.0062 19.0 9.1 1 23 542 564 542 564 0.98

14 18 9.6e-06 0.002 20.6 7.7 1 23 570 592 570 592 0.98

15 18 0.0042 0.86 12.3 10.6 1 21 598 618 598 620 0.94

16 18 0.00027 0.055 16.0 0.2 1 23 626 648 626 648 0.97

17 18 0.034 7.1 9.4 4.5 1 23 658 680 658 680 0.98

18 18 7.4e-07 0.00015 24.1 0.9 1 23 686 708 686 708 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.4e-05	0.0028	20.1	1.0	1	23	206	228	206	228	0.96
2	18	0.01	2.1	11.0	3.3	1	20	234	253	234	256	0.93
3	18	5.4e-06	0.0011	21.3	1.2	1	23	262	284	262	284	0.99
4	18	7.1e-05	0.015	17.8	3.5	1	21	290	310	290	312	0.94
5	18	0.00014	0.029	16.9	4.7	1	23	318	340	318	340	0.99
6	18	2.8e-05	0.0058	19.1	5.3	1	23	346	368	346	368	0.97
7	18	1.4e-06	0.00029	23.2	3.9	1	23	374	396	374	396	0.96
8	18	1e-07	2.2e-05	26.7	2.7	1	23	402	424	402	424	0.98
9	18	7.8e-05	0.016	17.7	6.7	1	23	430	452	430	452	0.97
10	18	7.7e-05	0.016	17.7	5.7	1	23	458	480	458	480	0.97
11	18	6.4e-07	0.00013	24.3	2.9	1	23	486	508	486	508	0.98
12	18	9.5e-06	0.002	20.6	7.8	1	23	514	536	514	536	0.98
13	18	3e-05	0.0062	19.0	9.1	1	23	542	564	542	564	0.98
14	18	9.6e-06	0.002	20.6	7.7	1	23	570	592	570	592	0.98
15	18	0.0042	0.86	12.3	10.6	1	21	598	618	598	620	0.94
16	18	0.00027	0.055	16.0	0.2	1	23	626	648	626	648	0.97
17	18	0.034	7.1	9.4	4.5	1	23	658	680	658	680	0.98
18	18	7.4e-07	0.00015	24.1	0.9	1	23	686	708	686	708	0.96

Sequence Information

Coding Sequence: ATGCTTAAGACTGTCCTCATTGAGGCACTATATCAAATTGTGCAGCTTGCTCAACAGCAACAACAGCAGCCTCATCAGCACCAACAACAGCCTCATCAACACCAGCAAGGTCAAACTGAGGCGAATAGAGAACTCCAACAATCCCAAGAGGTGGGTACACAAATGGACTCAGCAGGTGCCTCTGAGGTGAAGGATGAGAAAACTTCAAGCAGTGGGCCATGTGCAAAGGAACTGCGTAGCTTGCCCTGCACAGCTGGATTCCCTGTGCAAGATATGAAAGGTCACATGATGGACATCAGGACTCCAGATGGTAGCATTGTTAAAATCAGTGCTCCTGGCAATGGCGACCAGGAGTTGAGCAAGACCCTTGGTGTGGAGATGGTTCAGAACATGTATAAGGTCAATGTTGAAGATATCAACCAACTCCTTGCCTATCATGAGGTTTTCGGAAAGCTCCAGAATGAGATGGCAGCTGCTGGCGTCCCTGCACAGACTACCCCAACCACCTCAAGTACAAGTGGGACTGGGGTTAATAAATCATGTACTGGCGAACCGTGCTCTACCAATAGCAGTGTGACCACCTTACCAACTGCAGTCATCACCACTCCAGGCACGCATATCTGCGACATCTGTGGCAAGATTTTCCCTTTCCGGTACCAACTGATAGTCCATCGCCGCTACCACACTGAGAGGAAGCCATTTACTTGTCAGgTATGTGGGAAAGCCTTCACATGTGCTGCAGAACTCACACGACATGGGAAATGCCACCTTGGTGGCAGCATGTACACATGTTCTGTTTGTTTCCACGTGTTTGCCAACGCAGCTAGCCTGGAGCGTCATATGAAAAGACATGCAACAGACAAACCATATGCGTGCTCGGTGTGCGGGAAATCATTTGCTCGCAAAGAGCATTTGGACAATCATACAAGGTGCCACACAGGTGAGACGCCCTATCGTTGTCAGTTCTGTGCCAAGACATTCACACGCAAAGAACACATGGTTAATCATGTACGCAAGCACACAGGCGAGACCCCCCATCGCTGTGATATCTGCAAAAAATCATTCACTCGCAAGGAGCATTTCATGAACCATGTAATGTGGCACACAGGTGAGACACCCCATGCCTGTCAGGTTTGCGGCAAAAAGTACACAAGAAAAGAACACTTGGCCAATCACATGCGCTCCCACACCAATGACACACCCTTTCGCTGCGAGATCTGTGGCAAATCATTCACACGGAAGGAGCATTTCACGAACCACATCATGTGGCACACAGGCGAGACGCCGCATCGCTGTGACTTCTGCTCCAAGACTTTCACACGCAAGGAGCACCTGCTGAATCATGTCCGGCAGCATACGGGTGAGTCCCCCCATCGCTGCGGCTTCTGCTCCAAGTCTTTCACTCGCAAGGAGCACTTGGTGAATCATGTGCGCCAACATACTGGTGAGACCCCTTTCCGGTGCCAGTACTGCCCAAAGGCGTTCACACGCAAAGACCATCTGGTGAATCACGTTCGCCAGCACACAGGTGAGTCCCCCCACAAGTGTCAGTATTGCACCAAGTCGTTCACGCGCAAAGAGCACCTGACAAACCACGTGCGTCAGCACACGGGCGAGTCCCCCCATCGCTGCCACTTCTGTTCGAAATCCTTTACTCGCAAAGAGCATCTGACCAACCATGTGCGCATCCACACAGGTGAGTCGCCGCACCGCTGTGAGTTCTGCAACAAGACGTTCACACGCAAGGAACATCTGACCAACCACTTGCGCCAGCACACAGGAGAGACACCTCATTGCTGCCACGTCTGCTCCAAACCCTTCACACGTAAAGAGCACCTTGTCAACCACATGCGTTGTCACACGGGTGAGCGCCCCTTCGCTTGCCAGGAATGTGGCAAGGCATTCCCACTCAAGGGAAACTTGCTCTTCCATCAGCGCTCCCACAACAAGGGTGCCGCTGCTGAGCGACCTTTTCGCTGTGACCTTTGTCCCAAGGACTTCATGTGTAAGGGCCACCTAGTTTCTCATCGACGAAGTCACTCCGGAGACCGGCCCCATGCCTGTCCAGACTGTGGCAAAACATTTGTGGAGAAGGGCAACATGCTACGGCACCTTCGCAAGCACTCTGCAGATGGCCAGAGCCTTCATAACCCACCAGGAGGTGTGGTGGTGCCACCCTCACATCACCTGCAGCAGCACCATCCCGTGCCCCCACATGGACCTGTGGTTGTTCCCACGCCTAACGCTGCTGTGCTTTCTACCTACTGA
Protein Sequence: MLKTVLIEALYQIVQLAQQQQQQPHQHQQQPHQHQQGQTEANRELQQSQEVGTQMDSAGASEVKDEKTSSSGPCAKELRSLPCTAGFPVQDMKGHMMDIRTPDGSIVKISAPGNGDQELSKTLGVEMVQNMYKVNVEDINQLLAYHEVFGKLQNEMAAAGVPAQTTPTTSSTSGTGVNKSCTGEPCSTNSSVTTLPTAVITTPGTHICDICGKIFPFRYQLIVHRRYHTERKPFTCQVCGKAFTCAAELTRHGKCHLGGSMYTCSVCFHVFANAASLERHMKRHATDKPYACSVCGKSFARKEHLDNHTRCHTGETPYRCQFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHACQVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCGFCSKSFTRKEHLVNHVRQHTGETPFRCQYCPKAFTRKDHLVNHVRQHTGESPHKCQYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCNKTFTRKEHLTNHLRQHTGETPHCCHVCSKPFTRKEHLVNHMRCHTGERPFACQECGKAFPLKGNLLFHQRSHNKGAAAERPFRCDLCPKDFMCKGHLVSHRRSHSGDRPHACPDCGKTFVEKGNMLRHLRKHSADGQSLHNPPGGVVVPPSHHLQQHHPVPPHGPVVVPTPNAAVLSTY*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01446810;
90% Identity: iTF_01446810;
80% Identity: iTF_01450793;